OqxA is a transport protein of the Resistance-Nodulation-Cel...

created [InstanceEdit:9913677] Stephan, Ralf, 2024-06-17
dbId 9913667
displayName OqxA is a transport protein of the Resistance-Nodulation-Cel...
modified [InstanceEdit:9915279] Stephan, Ralf, 2024-07-04
schemaClass Summation
text OqxA is a transport protein of the Resistance-Nodulation-Cell Division (RND) superfamily which localizes to the plasma membrane. Members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism, utilizing the proton-motive force (reviewed in Nikaido, 2018). The oqxA gene has been found on plasmids of fluoroquinolone-resistant E.coli, and the protein exports a wide variety of antimicrobials (Hansen et al., 2004; Hansen et al., 2007; reviewed in Ruiz et al., 2012; Shariati et al., 2022).
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