Reactome | 84 on 2023-03-29

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84 on 2023-03-29 Show undefined attributes

dbId	9846594
displayName	84 on 2023-03-29
modified	[InstanceEdit:9982963] Weiser, Joel, 2026-02-20
releaseDate	2023-03-29
releaseNumber	84
schemaClass	Release

Referrals

(release)

[UpdateTracker:9904744] Update Tracker - [Complex:5617473] HOXD1 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904698] Update Tracker - [EntityWithAccessionedSequence:450619] p-T243-TNFSF13 [cytosol] - v84:[modifyName]
[UpdateTracker:9846637] Update Tracker - [Pathway:5663205] Infectious disease - v84:[add_removeHasEvent, modifyText]
[UpdateTracker:9904770] Update Tracker - [Complex:8980063] alpha beta dimer:Ii trimer [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846731] Update Tracker - [Pathway:9009391] Extra-nuclear estrogen signaling - v84:[updateIndirectRLE]
[UpdateTracker:9846755] Update Tracker - [Pathway:389513] CTLA4 inhibitory signaling - v84:[updateContainedRLE]
[UpdateTracker:9846607] Update Tracker - [Pathway:202403] TCR signaling - v84:[updateIndirectRLE]
[UpdateTracker:9905066] Update Tracker - [Complex:2130491] Nonameric complex [trans-Golgi network membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846617] Update Tracker - [Pathway:9660821] ADORA2B mediated anti-inflammatory cytokines production - v84:[updateContainedRLE]
[UpdateTracker:9904796] Update Tracker - [Complex:8983180] p-Y-STAT3:p-STAT5A,p-STAT5B [cytosol] - v84:[updateContainedComponent]
[UpdateTracker:9846600] Update Tracker - [Pathway:68884] Mitotic Telophase/Cytokinesis - v84:[updateContainedRLE]
[UpdateTracker:9846716] Update Tracker - [Reaction:1247841] PLCG1 binds to ligand-responsive p-6Y-EGFR mutants - v84:[modifyText]
[UpdateTracker:9904481] Update Tracker - [EntityWithAccessionedSequence:6783031] Ub-105-UBC(77-152) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904730] Update Tracker - [EntityWithAccessionedSequence:2768996] NICD1 P2514Rfs*4 [cytosol] - v84:[add_removeHasModifiedResidue]
[UpdateTracker:9905038] Update Tracker - [Complex:210244] HLA-C1:KIR2DS2:DAP12 dimer:KIR2DS2:HLA-C1 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904615] Update Tracker - [Complex:8987026] IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1,p-STAT3 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846599] Update Tracker - [Reaction:8871373] BMX phosphorylates RUFY1 - v84:[modifyText]
[UpdateTracker:9904700] Update Tracker - [EntityWithAccessionedSequence:5215951] p-Y389,400-RUFY1 [early endosome membrane] - v84:[modifyName]
[UpdateTracker:9904640] Update Tracker - [Complex:1236922] Class I MHC HC:B2M:Erp57 [phagocytic vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905058] Update Tracker - [Complex:5693590] RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846669] Update Tracker - [Pathway:881907] Gastrin-CREB signalling pathway via PKC and MAPK - v84:[updateContainedRLE]
[UpdateTracker:9904905] Update Tracker - [EntityWithAccessionedSequence:6782591] Ub-109-UBB(77-152) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904970] Update Tracker - [EntityWithAccessionedSequence:450229] p-S218,T222-MAP2K3 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904576] Update Tracker - [Complex:3211736] Chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904501] Update Tracker - [EntityWithAccessionedSequence:206040] p-T481,S486,S493-AXIN1 [cytosol] - v84:[modifyName]
[UpdateTracker:9904748] Update Tracker - [EntityWithAccessionedSequence:2471748] RDH12 Ala269Glyfs*2 [photoreceptor inner segment membrane] - v84:[addHasModifiedResidue, modifyName]
[UpdateTracker:9904583] Update Tracker - [Complex:5617645] HOXA3 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904451] Update Tracker - [Complex:8987053] IL24:IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904890] Update Tracker - [Complex:5621001] HOXB1:PBX1:PKNOX1 at active HOXA2 chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904504] Update Tracker - [EntityWithAccessionedSequence:6782603] Ub-179-UBC(153-228) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846695] Update Tracker - [Pathway:72172] mRNA Splicing - v84:[updateContainedPathway]
[UpdateTracker:9846757] Update Tracker - [Reaction:3928595] N-WASP binds ARP2/3 and G-actin - v84:[modifyText]
[UpdateTracker:9904816] Update Tracker - [DefinedSet:8867603] CLASP proteins:cargo [plasma membrane] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904521] Update Tracker - [Complex:2685711] DAG:p-5Y-PKC-theta:p-S559,S652-CARMA1 [plasma membrane] - v84:[modifyName]
[UpdateTracker:9846739] Update Tracker - [Reaction:71660] 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O - v84:[addLiteratureReference, modifyText]
[UpdateTracker:9904830] Update Tracker - [Complex:9021924] MECP2:p-S133-CREB1:SST gene [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905077] Update Tracker - [Complex:199592] LILR-interacting MHC Class I molecules [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904613] Update Tracker - [Complex:5625863] p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904694] Update Tracker - [Complex:8865497] SPI1 gene:H4K3me3-Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904528] Update Tracker - [DefinedSet:2130690] HLA II beta chain [clathrin-coated endocytic vesicle membrane] - v84:[removeHasMember]
[UpdateTracker:9904717] Update Tracker - [EntityWithAccessionedSequence:217297] p-S91-BAD [cytosol] - v84:[modifyName]
[UpdateTracker:9904872] Update Tracker - [Complex:2294607] Phosphorylated Condensin II:Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904985] Update Tracker - [Complex:8936988] RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904839] Update Tracker - [Complex:5617482] HOXB2 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905100] Update Tracker - [Complex:1214200] Nucleosome with H3K4me2 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905056] Update Tracker - [Complex:3364023] MYC gene: H2B K121ub nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846728] Update Tracker - [Pathway:418594] G alpha (i) signalling events - v84:[updateContainedRLE]
[UpdateTracker:9904591] Update Tracker - [Complex:2272718] KIR2DS2:HLA-C1 (Cw3) [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904780] Update Tracker - [EntityWithAccessionedSequence:5689145] Ub-559-UBC(533-608) [cytosol] - v84:[modifyName]
[UpdateTracker:9904636] Update Tracker - [Complex:3451132] Acetyl H4- Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904464] Update Tracker - [EntityWithAccessionedSequence:5688015] SFTPB Q45Kfs*8 [endoplasmic reticulum membrane] - v84:[addLiteratureReference, addName, modifyEndCoordinate]
[UpdateTracker:9905039] Update Tracker - [EntityWithAccessionedSequence:5689183] Ub-105-UBC(77-152) [cytosol] - v84:[modifyName]
[UpdateTracker:9905105] Update Tracker - [EntityWithAccessionedSequence:6782599] Ub-489-UBC(457-532) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904537] Update Tracker - [Complex:5625860] Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904533] Update Tracker - [DefinedSet:5357488] VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K/VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y772,Y814-AXL:PI3K [plasma membrane] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904480] Update Tracker - [Complex:2213211] Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904648] Update Tracker - [EntityWithAccessionedSequence:5689176] Ub-485-UBC(457-532) [cytosol] - v84:[modifyName]
[UpdateTracker:9904623] Update Tracker - [EntityWithAccessionedSequence:6782652] Ub-105-UBB(77-152) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904768] Update Tracker - [Complex:983119] MHC class I HC:Calnexin/BiP:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904688] Update Tracker - [EntityWithAccessionedSequence:143488] p-S124-CDC25A [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904973] Update Tracker - [EntityWithAccessionedSequence:8871352] p-Y389,400-RUFY1 [cytosol] - v84:[modifyName]
[UpdateTracker:9904809] Update Tracker - [EntityWithAccessionedSequence:391102] p-Y429,Y453,Y470,Y496-SIRPA [plasma membrane] - v84:[modifyName]
[UpdateTracker:9905080] Update Tracker - [EntityWithAccessionedSequence:6782640] Ub-261-UBC(229-304) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846612] Update Tracker - [Reaction:140761] sequestered tissue factor -> tissue factor - v84:[modifyText]
[UpdateTracker:9904535] Update Tracker - [Complex:8987258] IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904654] Update Tracker - [Complex:5683605] DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904439] Update Tracker - [Complex:2213227] peptide free MHC II:HLA-DM [lysosomal membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846614] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v84:[updateContainedRLE]
[UpdateTracker:9846754] Update Tracker - [BlackBoxEvent:9708466] p-Y483 BACH1 translocates from the nucleoplasm to the cytosol - v84:[modifyText]
[UpdateTracker:9904977] Update Tracker - [Complex:9011926] GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904560] Update Tracker - [Complex:606328] CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904549] Update Tracker - [EntityWithAccessionedSequence:9014875] p-S182,T184,T186-RUNX2-P2 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846685] Update Tracker - [Pathway:202424] Downstream TCR signaling - v84:[updateContainedRLE]
[UpdateTracker:9904952] Update Tracker - [Complex:2130680] MHC II:lip22 nonamer [lysosomal membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904574] Update Tracker - [Complex:5685162] ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846717] Update Tracker - [Reaction:1248655] Trans-autophosphorylation of EGFRvIII mutant dimers - v84:[modifyText]
[UpdateTracker:9846621] Update Tracker - [Pathway:9634638] Estrogen-dependent nuclear events downstream of ESR-membrane signaling - v84:[updateContainedRLE]
[UpdateTracker:9846782] Update Tracker - [Pathway:9679191] Potential therapeutics for SARS - v84:[updateContainedRLE]
[UpdateTracker:9904665] Update Tracker - [DefinedSet:2130476] HLA II beta chain [plasma membrane] - v84:[removeHasMember]
[UpdateTracker:9904536] Update Tracker - [EntityWithAccessionedSequence:5601997] CYP24A1 E151* [mitochondrial inner membrane] - v84:[addHasModifiedResidue]
[UpdateTracker:9846661] Update Tracker - [Pathway:73887] Death Receptor Signaling - v84:[updateContainedPathway]
[UpdateTracker:9905043] Update Tracker - [EntityWithAccessionedSequence:111910] p-S133-CREB1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905094] Update Tracker - [EntityWithAccessionedSequence:450603] p-T243-TNFSF13 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904834] Update Tracker - [Complex:606295] Centromeric Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905041] Update Tracker - [Complex:5334149] Chromatin with hemimethylC [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904638] Update Tracker - [Complex:5334119] DNMT3A:DNMT3L:Chromatin with 5mC [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904854] Update Tracker - [Complex:2130531] Nonameric complex [endocytic vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904826] Update Tracker - [Complex:8936485] H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904711] Update Tracker - [Complex:8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904916] Update Tracker - [CandidateSet:199591] LILR-binding HLA Class I [plasma membrane] - v84:[removeHasCandidate, removeHasMember, updateContainedMemberOrCandidate]
[UpdateTracker:9904540] Update Tracker - [Complex:202154] Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904753] Update Tracker - [EntityWithAccessionedSequence:9627087] p-T412-CASP9(1-416) [cytosol] - v84:[modifyName]
[UpdateTracker:9846752] Update Tracker - [Pathway:429914] Deadenylation-dependent mRNA decay - v84:[updateIndirectRLE]
[UpdateTracker:9904445] Update Tracker - [EntityWithAccessionedSequence:6783114] Ub-179-UBB(153-228) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904784] Update Tracker - [Complex:983136] MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846745] Update Tracker - [Pathway:434136] Viral dsRNA:TLR3:TICAM1 Complex Activates TBK1 - v84:[updateContainedRLE]
[UpdateTracker:9846779] Update Tracker - [Pathway:163685] Integration of energy metabolism - v84:[updateIndirectRLE]
[UpdateTracker:9904932] Update Tracker - [Complex:8866261] EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905018] Update Tracker - [EntityWithAccessionedSequence:6782597] Ub-635-UBC(609-684) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846733] Update Tracker - [Pathway:9772573] Late SARS-CoV-2 Infection Events - v84:[updateIndirectRLE]
[UpdateTracker:9904486] Update Tracker - [Complex:2288093] Condensin II:Nucleosome with H4K20me1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846687] Update Tracker - [Reaction:140686] factor Va + factor Xa -> Va:Xa complex (prothrombinase) - v84:[modifyText]
[UpdateTracker:9846630] Update Tracker - [Reaction:164113] Dephosphorylation of prChREBP (Ser 196) by rPP2A - v84:[modifyText]
[UpdateTracker:9904444] Update Tracker - [EntityWithAccessionedSequence:5689203] Ub-109-UBB(77-152) [cytosol] - v84:[modifyName]
[UpdateTracker:9905048] Update Tracker - [Complex:2130723] MHC II:lip10 nonamer [lysosomal membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846692] Update Tracker - [Pathway:111458] Formation of apoptosome - v84:[updateIndirectRLE]
[UpdateTracker:9846708] Update Tracker - [Pathway:68875] Mitotic Prophase - v84:[updateContainedPathway]
[UpdateTracker:9904881] Update Tracker - [EntityWithAccessionedSequence:6783008] Ub-109-UBB(77-152) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9846807] Update Tracker - [Reaction:5692779] p-T182 MAPKAPK5 phosphorylates FOXO1 - v84:[modifyText]
[UpdateTracker:9904532] Update Tracker - [EntityWithAccessionedSequence:9707290] K6PolyUb,p-S1387,S1423,S1457,S1524-BRCA1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904813] Update Tracker - [EntityWithAccessionedSequence:2454229] p-Y397-LYN [plasma membrane] - v84:[modifyName]
[UpdateTracker:9904472] Update Tracker - [Complex:199565] HLA Bw4 interacting with KIR3DL1 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904653] Update Tracker - [Complex:140751] factor VIIa [extracellular region] - v84:[addName]
[UpdateTracker:9904814] Update Tracker - [Complex:167755] Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904838] Update Tracker - [Complex:5685161] p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904793] Update Tracker - [Complex:9629401] Sp-Telomeric DNA:Shelterin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904719] Update Tracker - [Complex:5685826] D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904810] Update Tracker - [EntityWithAccessionedSequence:5262978] IKBKG *420Wext*447 [cytosol] - v84:[modifyEndCoordinate, modifyName]
[UpdateTracker:9846673] Update Tracker - [Reaction:8964242] G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC - v84:[modifyText]
[UpdateTracker:9846802] Update Tracker - [Pathway:166166] MyD88-independent TLR4 cascade - v84:[updateContainedPathway]
[UpdateTracker:9904818] Update Tracker - [Complex:2245194] Nucleosome with H3K4me2/3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904994] Update Tracker - [EntityWithAccessionedSequence:6783077] Ub-409-UBC(381-456) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904888] Update Tracker - [Complex:9011913] KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904835] Update Tracker - [EntityWithAccessionedSequence:8943073] K48polyUb-HLA-A A-2 [endoplasmic reticulum membrane] - v84:[add_removeReferenceEntity]
[UpdateTracker:9904958] Update Tracker - [EntityWithAccessionedSequence:6810226] p-S5,S7(CTD)-POLR2A [nucleoplasm] - v84:[addHasModifiedResidue, modifyName]
[UpdateTracker:9905017] Update Tracker - [Complex:1236916] IRAP in complex with MHC class I [early endosome membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846725] Update Tracker - [Reaction:2028589] Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) - v84:[modifyText]
[UpdateTracker:9904579] Update Tracker - [EntityWithAccessionedSequence:5692651] p-S218-FOXO1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846732] Update Tracker - [Pathway:1236382] Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants - v84:[updateContainedRLE]
[UpdateTracker:9904515] Update Tracker - [EntityWithAccessionedSequence:6783188] Ub-637-UBC(609-684) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9846619] Update Tracker - [Reaction:9612501] SGK phosphorylates CREB1 - v84:[modifyText]
[UpdateTracker:9904594] Update Tracker - [EntityWithAccessionedSequence:164365] p-T653-MLXIPL [cytosol] - v84:[modifyName]
[UpdateTracker:9846766] Update Tracker - [Reaction:1225949] Binding of CBL to ligand-responsive p-6Y-EGFR mutants - v84:[modifyText]
[UpdateTracker:9904668] Update Tracker - [EntityWithAccessionedSequence:5578664] MSH3 K383Rfs*32 [nucleoplasm] - v84:[modifyEndCoordinate, modifyName]
[UpdateTracker:9904887] Update Tracker - [Complex:9756725] p-2S-Smad2,3:Trim33:p-2S-Smad2,3:Smad4:Foxh1Mixl1 gene [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904732] Update Tracker - [Complex:391116] p-Y429,Y453,Y470,Y496y-SIRPA:CD47:SKAP2:FYB [plasma membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9846611] Update Tracker - [Pathway:5637810] Constitutive Signaling by EGFRvIII - v84:[modifyText, updateContainedRLE]
[UpdateTracker:9904512] Update Tracker - [Complex:8936607] RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904616] Update Tracker - [EntityWithAccessionedSequence:6782636] Ub-413-UBC(381-456) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904846] Update Tracker - [Complex:9652116] MAP2K1 L42_K57del dimer [cytosol] - v84:[modifyName]
[UpdateTracker:9846718] Update Tracker - [Pathway:9727281] Translation of Accessory Proteins - v84:[updateContainedRLE]
[UpdateTracker:9904678] Update Tracker - [EntityWithAccessionedSequence:9669444] KIT K550I;P551_V555del [plasma membrane] - v84:[modifyName]
[UpdateTracker:9905062] Update Tracker - [EntityWithAccessionedSequence:6783078] Ub-489-UBC(457-532) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9846640] Update Tracker - [Reaction:163670] Nuclear transport of pChREBP (Thr 666) protein - v84:[modifyText]
[UpdateTracker:9846736] Update Tracker - [Pathway:70171] Glycolysis - v84:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9846702] Update Tracker - [Pathway:9759194] Nuclear events mediated by NFE2L2 - v84:[updateIndirectRLE]
[UpdateTracker:9846664] Update Tracker - [Pathway:168164] Toll Like Receptor 3 (TLR3) Cascade - v84:[updateContainedPathway]
[UpdateTracker:9846815] Update Tracker - [Pathway:437987] Toll-like receptors (TLR) cascades - v84:[updateContainedPathway]
[UpdateTracker:9904849] Update Tracker - [DefinedSet:8943116] HLA A-2,A-3,B-60 [endoplasmic reticulum membrane] - v84:[removeHasMember]
[UpdateTracker:9904523] Update Tracker - [EntityWithAccessionedSequence:9707298] K6PolyUb,p-S988,S1387,S1423,S1457,S1524-BRCA1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905070] Update Tracker - [Complex:983114] Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846806] Update Tracker - [Reaction:111916] Dimerization of p-S119-CREB1 - v84:[modifyText]
[UpdateTracker:9846620] Update Tracker - [Reaction:8871376] p-Y389,400-RUFY1 binds PI3P - v84:[modifyText]
[UpdateTracker:9904607] Update Tracker - [Complex:427405] Nucleosome (H4K5ac, H4K8ac, H4K12ac, H4K16ac) [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905074] Update Tracker - [EntityWithAccessionedSequence:180287] p-4Y-EGFR [plasma membrane] - v84:[modifyName]
[UpdateTracker:9904669] Update Tracker - [Complex:427343] Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904827] Update Tracker - [Complex:918199] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2xTBK1,IKBKE:IRF3,IRF7 [mitochondrial outer membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904752] Update Tracker - [EntityWithAccessionedSequence:9762048] p-S344, S347,T-NFE2L2 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846799] Update Tracker - [Pathway:9754678] SARS-CoV-2 modulates host translation machinery - v84:[updateContainedRLE]
[UpdateTracker:9904769] Update Tracker - [EntityWithAccessionedSequence:6782655] Ub-185-UBB(153-228) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904895] Update Tracker - [Complex:5685317] 3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846776] Update Tracker - [Pathway:198725] Nuclear Events (kinase and transcription factor activation) - v84:[updateIndirectRLE]
[UpdateTracker:9904909] Update Tracker - [Complex:182254] Nef:class I MHC complex:AP-1:PACS-1 Complex [early endosome membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904491] Update Tracker - [Complex:983132] Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904682] Update Tracker - [Complex:9604905] SIRT6:Nucleosome:NOTCH4 gene [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904511] Update Tracker - [Complex:428494] Sos:PAK:Dock:Robo:Slit [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904962] Update Tracker - [Complex:3222592] CDKN2A Gene:Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904641] Update Tracker - [Complex:427331] Nucleosome with H3K9me2 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905103] Update Tracker - [Complex:8983137] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-STAT3,p-STAT5,(p-Y-STAT3:p-STAT5) [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904671] Update Tracker - [EntityWithAccessionedSequence:5689146] Ub-185-UBB(153-228) [cytosol] - v84:[modifyName]
[UpdateTracker:9846646] Update Tracker - [Pathway:111933] Calmodulin induced events - v84:[updateIndirectRLE]
[UpdateTracker:9904989] Update Tracker - [Complex:2130331] Clathrin coated MHC class II alpha/beta/Ii nonamer [clathrin-coated endocytic vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904632] Update Tracker - [Complex:5617876] RARA,B:RXRA at HOXA4 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904918] Update Tracker - [Complex:3451116] TCF4 gene:nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905006] Update Tracker - [EntityWithAccessionedSequence:4754224] KDM6A [nucleoplasm] - v84:[addName]
[UpdateTracker:9904869] Update Tracker - [Complex:912372] Telomere Attachment Plate [nuclear envelope] - v84:[updateContainedComponent]
[UpdateTracker:9904841] Update Tracker - [CandidateSet:181899] Histone H2A [nucleoplasm] - v84:[removeHasCandidate]
[UpdateTracker:9904625] Update Tracker - [EntityWithAccessionedSequence:6782620] Ub-337-UBC(305-380) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846680] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v84:[updateContainedRLE]
[UpdateTracker:9904507] Update Tracker - [Complex:5625795] p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846763] Update Tracker - [Reaction:158118] factor VIII + von Willebrand factor multimer -> factor VIII:von Willibrand factor multimer - v84:[modifyText]
[UpdateTracker:9846820] Update Tracker - [Reaction:9615367] Prkaca phosphorylates Creb1 - v84:[modifyText]
[UpdateTracker:9905102] Update Tracker - [EntityWithAccessionedSequence:9673205] F9(29-461) R43L [extracellular region] - v84:[modifyName]
[UpdateTracker:9904725] Update Tracker - [Complex:8987239] IL20RA:p-Y1034,Y1035-JAK1 [plasma membrane] - v84:[modifyName]
[UpdateTracker:9904889] Update Tracker - [EntityWithAccessionedSequence:5689144] Ub-635-UBC(609-684) [cytosol] - v84:[modifyName]
[UpdateTracker:9846746] Update Tracker - [Reaction:199895] RSK1/2/3 phosphorylates CREB at Serine 119 - v84:[modifyText]
[UpdateTracker:9904570] Update Tracker - [Complex:182928] EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] - v84:[addName]
[UpdateTracker:9904743] Update Tracker - [Complex:3364035] Nucleosome with H2BK121ub and H3K4me3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904624] Update Tracker - [EntityWithAccessionedSequence:9628869] UNC93B1 L230Afs*188 [endoplasmic reticulum membrane] - v84:[modifyName]
[UpdateTracker:9904747] Update Tracker - [EntityWithAccessionedSequence:6782621] Ub-257-UBC(229-304) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904633] Update Tracker - [Complex:5617663] HOXD3 active chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904782] Update Tracker - [EntityWithAccessionedSequence:5689205] Ub-565-UBC(533-608) [cytosol] - v84:[modifyName]
[UpdateTracker:9904763] Update Tracker - [Complex:9022198] MECP2:p-S133-CREB1:SLC2A3 gene [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904804] Update Tracker - [EntityWithAccessionedSequence:9762206] p-Y483 BACH1 [cytosol] - v84:[modifyName]
[UpdateTracker:9904606] Update Tracker - [EntityWithAccessionedSequence:9662489] RB1 Q504* [cytosol] - v84:[add_removeHasModifiedResidue]
[UpdateTracker:9904666] Update Tracker - [DefinedSet:6806534] Secretory granule membrane proteins [plasma membrane] - v84:[removeHasMember]
[UpdateTracker:9904520] Update Tracker - [EntityWithAccessionedSequence:9005335] p-Y1034,Y1035-JAK1 [cytosol] - v84:[modifyName]
[UpdateTracker:9846792] Update Tracker - [Pathway:9708530] Regulation of BACH1 activity - v84:[updateContainedRLE]
[UpdateTracker:9904913] Update Tracker - [Complex:5685178] ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904840] Update Tracker - [DefinedSet:9604903] SIRT6:Nucleosome:NOTCH1,NOTCH4 gene [nucleoplasm] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904720] Update Tracker - [Complex:8951496] Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904981] Update Tracker - [Complex:9755340] 8:antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904619] Update Tracker - [Complex:182939] EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] - v84:[addName, updateContainedComponent]
[UpdateTracker:9904858] Update Tracker - [Complex:9629187] Gh-Telomeric DNA:Shelterin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904514] Update Tracker - [EntityWithAccessionedSequence:3828056] GYS1 R462* [cytosol] - v84:[addHasModifiedResidue]
[UpdateTracker:9846797] Update Tracker - [Reaction:9627089] CASP9 is phosphorylated at T412 - v84:[modifyText]
[UpdateTracker:9904699] Update Tracker - [Complex:2294604] Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846635] Update Tracker - [Reaction:8878050] HIPK2 phosphorylates RUNX1 and EP300 - v84:[modifyText]
[UpdateTracker:9904886] Update Tracker - [Complex:9011915] KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904978] Update Tracker - [Complex:5685989] 3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904927] Update Tracker - [Complex:2976561] NOTCH2 coactivator complex:p-S133-CREB1:EP300:GZMB Gene [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904842] Update Tracker - [EntityWithAccessionedSequence:448838] p-T293,T300,S387-MEF2C [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904762] Update Tracker - [EntityWithAccessionedSequence:6783128] Ub-635-UBC(609-684) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9846618] Update Tracker - [Pathway:9013973] TICAM1-dependent activation of IRF3/IRF7 - v84:[modifyText]
[UpdateTracker:9904482] Update Tracker - [DefinedSet:9707299] p-5S-BRCA1:p-2T-BARD1 [nucleoplasm] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904526] Update Tracker - [Complex:983416] Antigen peptide bound class I MHC [Golgi membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904637] Update Tracker - [Complex:8937013] H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904761] Update Tracker - [EntityWithAccessionedSequence:8878063] p-S249,S273,S276-RUNX1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904819] Update Tracker - [Complex:3788743] IL8 gene:Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846710] Update Tracker - [Pathway:9627069] Regulation of the apoptosome activity - v84:[updateContainedRLE]
[UpdateTracker:9904911] Update Tracker - [EntityWithAccessionedSequence:199081] Cdh1(157-884) [plasma membrane] - v84:[modifyName]
[UpdateTracker:9846689] Update Tracker - [Pathway:3928665] EPH-ephrin mediated repulsion of cells - v84:[updateContainedRLE]
[UpdateTracker:9846771] Update Tracker - [Reaction:1169421] Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers - v84:[modifyText]
[UpdateTracker:9846603] Update Tracker - [Reaction:164423] PhosphoChREBP (Thr 653) is exported to cytosol - v84:[modifyText]
[UpdateTracker:9904995] Update Tracker - [EntityWithAccessionedSequence:388754] p-Y201,Y218-CTLA4 [plasma membrane] - v84:[modifyName]
[UpdateTracker:9904518] Update Tracker - [Complex:5334140] UHRF1:Chromatin with hemimethylC [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904713] Update Tracker - [Complex:9011919] KDM4B gene:nucleoplasm:ESR1:ESTG [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904471] Update Tracker - [Complex:111911] p-S133-CREB1 homodimer [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846690] Update Tracker - [Pathway:8878171] Transcriptional regulation by RUNX1 - v84:[updateIndirectRLE]
[UpdateTracker:9904812] Update Tracker - [EntityWithAccessionedSequence:9704738] PALB2 C77Vfs*100 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904785] Update Tracker - [Complex:5625876] Nucleosome with p-T12-H3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904561] Update Tracker - [Complex:5684883] ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905049] Update Tracker - [EntityWithAccessionedSequence:5689214] Ub-181-UBB(153-228) [cytosol] - v84:[modifyName]
[UpdateTracker:9904714] Update Tracker - [DefinedSet:9009214] p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4,p-STAT5 [cytosol] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9846793] Update Tracker - [Pathway:163767] PP2A-mediated dephosphorylation of key metabolic factors - v84:[updateContainedRLE]
[UpdateTracker:9904873] Update Tracker - [Complex:5683806] p-5S,2T-BRCA1-A Complex [nucleoplasm] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9846678] Update Tracker - [Reaction:379842] Dimerization of p-S119-Creb1 - v84:[modifyText]
[UpdateTracker:9846735] Update Tracker - [Pathway:1483255] PI Metabolism - v84:[updateIndirectRLE]
[UpdateTracker:9904737] Update Tracker - [Complex:9009369] CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3:ESTG:ESR1 dimer:JUN:ATF2:POUF21:ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904880] Update Tracker - [Complex:5617662] HOXD3 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904944] Update Tracker - [EntityWithAccessionedSequence:9606455] MUTYH-3 A368fs*26 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904704] Update Tracker - [EntityWithAccessionedSequence:2769013] NICD1 P2514Rfs*4 [nucleoplasm] - v84:[add_removeHasModifiedResidue]
[UpdateTracker:9904800] Update Tracker - [Complex:2272705] HLA-Bw4:KIR3DS1:DAP12 dimer:KIR3DS1:HLA-Bw4 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904923] Update Tracker - [Complex:202345] phospho tyrosine ZAP-70 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846720] Update Tracker - [Pathway:1266738] Developmental Biology - v84:[updateContainedPathway]
[UpdateTracker:9904806] Update Tracker - [EntityWithAccessionedSequence:8941307] TUT4 [cytosol] - v84:[addName]
[UpdateTracker:9904950] Update Tracker - [Complex:8863933] Class I MHC HC:B2M:Erp57 [recycling endosome membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904592] Update Tracker - [Complex:5357453] VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL:PI3K [plasma membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9846767] Update Tracker - [Reaction:8941312] TUT4,TUT7 oligouridylate mRNA - v84:[addOutput, add_removeInput, modifyText]
[UpdateTracker:9904484] Update Tracker - [EntityWithAccessionedSequence:6783166] Ub-565-UBC(533-608) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904495] Update Tracker - [Complex:5625850] p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904984] Update Tracker - [EntityWithAccessionedSequence:75234] p-S1387,S1423,S1457,S1524-BRCA1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904660] Update Tracker - [Complex:5693552] RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904755] Update Tracker - [Complex:8936620] H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904567] Update Tracker - [EntityWithAccessionedSequence:8867028] p-Y849 EPS15 [cytosol] - v84:[modifyName]
[UpdateTracker:9904467] Update Tracker - [Complex:391113] p-Y428,Y452,Y469,Y495-SIRPA:CD47:PTK2B [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904441] Update Tracker - [EntityWithAccessionedSequence:2902208] NICD1 P2474Afs*4 [nucleoplasm] - v84:[addLiteratureReference, add_removeHasModifiedResidue]
[UpdateTracker:9846791] Update Tracker - [Pathway:2028269] Signaling by Hippo - v84:[updateContainedRLE]
[UpdateTracker:9904635] Update Tracker - [Complex:5617644] HOXB3 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904875] Update Tracker - [Complex:5617873] atRA:RARA,B:RXRA at active HOXA4 chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904706] Update Tracker - [Complex:8863840] EGF:p-Y992,Y1045,Y1068,Y1086,Y1173-EGFR:p-Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904976] Update Tracker - [Complex:5693638] HOXB1:PBX1:PKNOX1 and MEIS1 at active HOXB1 chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904823] Update Tracker - [DefinedSet:8863982] Class I MHC heavy chain (MHC HC) [recycling endosome membrane] - v84:[removeHasMember]
[UpdateTracker:9846808] Update Tracker - [Pathway:5683057] MAPK family signaling cascades - v84:[updateIndirectRLE]
[UpdateTracker:9904599] Update Tracker - [Complex:9612517] EGR1 gene:p-S133 CREB:p-S103 SRF [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904789] Update Tracker - [Complex:8987027] IL20RA:p-Y1034,Y1035-JAK1:IL20RB [plasma membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904777] Update Tracker - [DefinedSet:2214376] HLA II beta chain [Golgi membrane] - v84:[removeHasMember]
[UpdateTracker:9904479] Update Tracker - [Complex:6810168] HOXB3 active chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904772] Update Tracker - [Complex:5683737] DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex:CHEK2 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846772] Update Tracker - [Reaction:165766] Phosphorylation and activation of eIF4G by activated S6K1 - v84:[addLiteratureReference, modifyText]
[UpdateTracker:9904837] Update Tracker - [Complex:5683808] DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-5S,2T-BRCA1-A complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904934] Update Tracker - [Complex:5625783] KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904600] Update Tracker - [Complex:3321855] NSL (PHF20) [nucleoplasm] - v84:[addName]
[UpdateTracker:9904557] Update Tracker - [EntityWithAccessionedSequence:164349] p-T653-MLXIPL [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904593] Update Tracker - [Complex:3211709] PRC2:Chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904831] Update Tracker - [EntityWithAccessionedSequence:6782651] Ub-103-UBC(77-152) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904874] Update Tracker - [Complex:5625764] KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904551] Update Tracker - [Complex:5686228] Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846700] Update Tracker - [Reaction:2730862] Autophosphorylation of LYN kinase - v84:[modifyText]
[UpdateTracker:9904919] Update Tracker - [Complex:182256] Nef:class I MHC complex [Golgi membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904485] Update Tracker - [Complex:983413] Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846609] Update Tracker - [Pathway:163680] AMPK inhibits chREBP transcriptional activation activity - v84:[updateContainedRLE]
[UpdateTracker:9846783] Update Tracker - [Pathway:168898] Toll-like Receptor Cascades - v84:[updateContainedPathway]
[UpdateTracker:9846658] Update Tracker - [Reaction:70494] Enolase dimers (ENO1,2,3) convert PEP to 2PG - v84:[modifyText]
[UpdateTracker:9904898] Update Tracker - [Complex:198897] TCR interacting with antigen-bearing MHC Class I [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905051] Update Tracker - [EntityWithAccessionedSequence:6782641] Ub-255-UBC(229-304) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904853] Update Tracker - [Complex:8985918] p-Y407-IL9R:JAK1 [plasma membrane] - v84:[modifyName]
[UpdateTracker:9904907] Update Tracker - [EntityWithAccessionedSequence:8964276] p-Y419-SRC [cytosol] - v84:[modifyName]
[UpdateTracker:9904617] Update Tracker - [EntityWithAccessionedSequence:5689153] Ub-489-UBC(457-532) [cytosol] - v84:[modifyName]
[UpdateTracker:9905076] Update Tracker - [EntityWithAccessionedSequence:9629974] NTHL1 Q90* [nucleoplasm] - v84:[addHasModifiedResidue]
[UpdateTracker:9846691] Update Tracker - [Pathway:450282] MAPK targets/ Nuclear events mediated by MAP kinases - v84:[updateIndirectRLE]
[UpdateTracker:9905016] Update Tracker - [Complex:2130431] MHC class II alpha/beta/Ii nonamer [transport vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904685] Update Tracker - [EntityWithAccessionedSequence:9762050] p-S40, S344, S347- NFE2L2 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904864] Update Tracker - [Complex:5617447] Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846722] Update Tracker - [Pathway:1643713] Signaling by EGFR in Cancer - v84:[updateContainedPathway]
[UpdateTracker:9904987] Update Tracker - [Complex:5625776] p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904971] Update Tracker - [Complex:9009057] CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846604] Update Tracker - [Pathway:433819] Viral dsRNA:TLR3:TICAM1 Complex Activates IKBKE_CHICK - v84:[updateContainedRLE]
[UpdateTracker:9904555] Update Tracker - [Complex:6810160] HOXA3 active chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905057] Update Tracker - [EntityWithAccessionedSequence:9673193] F9(29-461) R46S [extracellular region] - v84:[modifyName]
[UpdateTracker:9904954] Update Tracker - [Complex:8985893] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904487] Update Tracker - [Complex:8871354] p-Y389,400-RUFY1:PI3P [early endosome membrane] - v84:[modifyName]
[UpdateTracker:9904920] Update Tracker - [Complex:9670098] Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904824] Update Tracker - [EntityWithAccessionedSequence:5654109] SLC39A4 Q323Qfs*25 [plasma membrane] - v84:[addLiteratureReference, modifyEndCoordinate, modifyName]
[UpdateTracker:9904566] Update Tracker - [Complex:2130532] Nonameric complex [lysosomal membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905026] Update Tracker - [EntityWithAccessionedSequence:5623707] SLC11A2 L104_P142del [plasma membrane] - v84:[addLiteratureReference, addName]
[UpdateTracker:9905096] Update Tracker - [Complex:5625748] Nucleosome with H3K9me3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904550] Update Tracker - [EntityWithAccessionedSequence:164351] p-S196,T653-MLXIPL [cytosol] - v84:[modifyName]
[UpdateTracker:9904901] Update Tracker - [Complex:182936] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] - v84:[addName]
[UpdateTracker:9904997] Update Tracker - [Complex:9604908] SIRT6:Nucleosome:NOTCH1 gene [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904548] Update Tracker - [EntityWithAccessionedSequence:5689151] Ub-561-UBC(533-608) [cytosol] - v84:[modifyName]
[UpdateTracker:9904741] Update Tracker - [EntityWithAccessionedSequence:9647476] NF1 A131Vfs*19 [cytosol] - v84:[modifyName]
[UpdateTracker:9904595] Update Tracker - [EntityWithAccessionedSequence:2028565] p-S872,T1041-LATS2 [cytosol] - v84:[modifyName]
[UpdateTracker:9846756] Update Tracker - [Reaction:9717136] p-Smad2,3:Smad4:Foxh1 binds Activin Response Element - v84:[add_removeInput]
[UpdateTracker:9846768] Update Tracker - [Reaction:5357776] TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG - v84:[modifyText]
[UpdateTracker:9904993] Update Tracker - [EntityWithAccessionedSequence:6782674] Ub-641-UBC(609-684) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846682] Update Tracker - [Pathway:73857] RNA Polymerase II Transcription - v84:[updateIndirectRLE]
[UpdateTracker:9905022] Update Tracker - [Complex:176703] Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846652] Update Tracker - [Reaction:442724] Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) - v84:[modifyText]
[UpdateTracker:9846789] Update Tracker - [Pathway:418555] G alpha (s) signalling events - v84:[updateContainedRLE]
[UpdateTracker:9904843] Update Tracker - [Complex:8931947] p-S133-CREB1:CRTC1,2,3:PPARGC1A gene [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904773] Update Tracker - [EntityWithAccessionedSequence:6783103] Ub-105-UBB(77-152) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9905063] Update Tracker - [Complex:8868234] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904693] Update Tracker - [EntityWithAccessionedSequence:163687] p-S556-MLXIPL [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904505] Update Tracker - [Complex:9709609] 3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:BRCA2 mutants (PALB2 binding):SEM1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846773] Update Tracker - [Reaction:5218850] VAV exchanges GTP for GDP on RAC1, activating it - v84:[modifyText]
[UpdateTracker:9904877] Update Tracker - [Complex:9710999] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2x(TBK1/IKBKE) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904453] Update Tracker - [Complex:2130477] Nonameric complex [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904531] Update Tracker - [Complex:9793411] Rbpj:Nicd:Tbx6 gene [nucleoplasm] - v84:[add_removeHasComponent, modifyName]
[UpdateTracker:9904914] Update Tracker - [Complex:8868051] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904674] Update Tracker - [EntityWithAccessionedSequence:2894873] NOTCH1 P2474Afs*4 Transmembrane Fragment [plasma membrane] - v84:[addLiteratureReference, add_removeHasModifiedResidue]
[UpdateTracker:9904808] Update Tracker - [Complex:427402] Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904629] Update Tracker - [Complex:5617870] HOXC4 active chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904611] Update Tracker - [EntityWithAccessionedSequence:2902193] NICD1 P2474Afs*4 [cytosol] - v84:[addLiteratureReference, add_removeHasModifiedResidue]
[UpdateTracker:9904951] Update Tracker - [Complex:199588] HLA-C group 1 interacting with KIR2DS2 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846721] Update Tracker - [Pathway:6807505] RNA polymerase II transcribes snRNA genes - v84:[updateContainedRLE]
[UpdateTracker:9904443] Update Tracker - [Complex:5617895] RARA,B:RXRA at HOXD4 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904605] Update Tracker - [Complex:391110] p-Y429,Y453,Y470,Y496-SIRPA:PTPN6,PTPN11 [plasma membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904883] Update Tracker - [Complex:5686615] p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904686] Update Tracker - [Complex:2213178] MHC class II alpha/beta dimer [clathrin-coated endocytic vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846693] Update Tracker - [BlackBoxEvent:8985973] IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 - v84:[modifyText]
[UpdateTracker:9846674] Update Tracker - [Reaction:183055] Binding of CBL to EGFR - v84:[modifyText]
[UpdateTracker:9904586] Update Tracker - [EntityWithAccessionedSequence:163473] p-S959,S960-Lipe [lipid droplet] - v84:[modifyName]
[UpdateTracker:9904562] Update Tracker - [EntityWithAccessionedSequence:8876892] Btn-p-S222-ACACB [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904938] Update Tracker - [DefinedSet:2130696] HLA II beta chain [endocytic vesicle membrane] - v84:[removeHasMember]
[UpdateTracker:9846813] Update Tracker - [Reaction:5607058] Activated protein C:PROCR binds F2R - v84:[modifyText]
[UpdateTracker:9904709] Update Tracker - [Complex:182294] class I MHC complex [early endosome membrane] - v84:[add_removeHasComponent]
[UpdateTracker:9904524] Update Tracker - [CandidateSet:8863989] Heterodimers of p-ERBB2 dephosphorylated at Y1248 [plasma membrane] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904517] Update Tracker - [EntityWithAccessionedSequence:2159809] p-NICD1 P2514Rfs*4 [nucleoplasm] - v84:[add_removeHasModifiedResidue]
[UpdateTracker:9846598] Update Tracker - [Pathway:182971] EGFR downregulation - v84:[updateContainedRLE]
[UpdateTracker:9905104] Update Tracker - [Complex:3788741] IL6 gene:Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904614] Update Tracker - [Complex:8876901] Btn-p-S222-ACACB:2Mn2+ [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9846804] Update Tracker - [Pathway:162582] Signal Transduction - v84:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904575] Update Tracker - [EntityWithAccessionedSequence:6783046] Ub-185-UBB(153-228) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9846596] Update Tracker - [Reaction:9729849] SARS-CoV-2 nsp1 binds to 40S ribosomal complex - v84:[addLiteratureReference, modifyText]
[UpdateTracker:9904947] Update Tracker - [Complex:8864028] EGF:p-EGFR dimer dephosphorylated at Y1172 (Y1148) [plasma membrane] - v84:[addName, updateContainedComponent]
[UpdateTracker:9904750] Update Tracker - [Complex:9623342] CCND1 gene:p-S133 CREB1 dimer [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905024] Update Tracker - [Complex:212288] DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904680] Update Tracker - [EntityWithAccessionedSequence:5621873] HK1 H577_C672del [cytosol] - v84:[modifyName]
[UpdateTracker:9904856] Update Tracker - [Complex:202181] Activated ZAP-70 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846719] Update Tracker - [Pathway:9705683] SARS-CoV-2-host interactions - v84:[updateIndirectRLE]
[UpdateTracker:9904778] Update Tracker - [Complex:9011878] MYC gene:nucleoplasm:ESR1:ESTG [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846764] Update Tracker - [Reaction:9709663] SARS-CoV-2 9b binds TOMM70 - v84:[addLiteratureReference, modifyText]
[UpdateTracker:9846602] Update Tracker - [Pathway:438064] Post NMDA receptor activation events - v84:[updateIndirectRLE]
[UpdateTracker:9904912] Update Tracker - [EntityWithAccessionedSequence:947562] PXLP-K198-NFS1-2 [cytosol] - v84:[modifyName]
[UpdateTracker:9846790] Update Tracker - [Reaction:5693551] Phosphorylation of BRCA1-A complex at multiple sites by ATM - v84:[modifyText]
[UpdateTracker:9904956] Update Tracker - [Complex:5617477] EGR2 at active HOXA2 chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904740] Update Tracker - [EntityWithAccessionedSequence:418427] p-S676,S689-MRVI1 [platelet dense tubular network membrane] - v84:[modifyName]
[UpdateTracker:9846679] Update Tracker - [Reaction:8985929] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B - v84:[modifyText]
[UpdateTracker:9904435] Update Tracker - [EntityWithAccessionedSequence:5689166] Ub-333-UBC(305-380) [cytosol] - v84:[modifyName]
[UpdateTracker:9904935] Update Tracker - [EntityWithAccessionedSequence:6783138] Ub-331-UBC(305-380) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9846608] Update Tracker - [Pathway:179812] GRB2 events in EGFR signaling - v84:[updateContainedRLE]
[UpdateTracker:9905089] Update Tracker - [DefinedSet:2130392] HLA II beta chain [lysosomal membrane] - v84:[removeHasMember]
[UpdateTracker:9846670] Update Tracker - [Pathway:5357786] TNFR1-induced proapoptotic signaling - v84:[updateContainedRLE]
[UpdateTracker:9846729] Update Tracker - [Reaction:388833] Phosphorylation of CTLA-4 - v84:[addLiteratureReference, modifyText]
[UpdateTracker:9904845] Update Tracker - [Complex:8936586] RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904896] Update Tracker - [Complex:5578688] AGO1,2:miRNA:chromatin:RNA pol II [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846751] Update Tracker - [Reaction:5357429] AXL autophosphorylates on Y779 and Y821 - v84:[modifyText]
[UpdateTracker:9846677] Update Tracker - [Pathway:2514859] Inactivation, recovery and regulation of the phototransduction cascade - v84:[updateContainedRLE]
[UpdateTracker:9904667] Update Tracker - [Complex:9664324] p-S133-CREB1:IL10 gene [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905023] Update Tracker - [Complex:182751] Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846632] Update Tracker - [Reaction:200555] acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate - v84:[modifyText]
[UpdateTracker:9846665] Update Tracker - [Pathway:4420097] VEGFA-VEGFR2 Pathway - v84:[updateContainedRLE]
[UpdateTracker:9905036] Update Tracker - [EntityWithAccessionedSequence:6783174] Ub-559-UBC(533-608) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904945] Update Tracker - [Complex:5686227] Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904811] Update Tracker - [Complex:1214169] Nucleosome with H3K4me3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904946] Update Tracker - [Complex:2272751] KIR3DS1:HLA-Bw4 [plasma membrane] - v84:[add_removeHasComponent]
[UpdateTracker:9904488] Update Tracker - [EntityWithAccessionedSequence:156695] p-S911,S912-KIF23 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846743] Update Tracker - [Pathway:5637812] Signaling by EGFRvIII in Cancer - v84:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904790] Update Tracker - [Complex:182948] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] - v84:[addName]
[UpdateTracker:9846730] Update Tracker - [BlackBoxEvent:8871370] p-Y389,400-RUFY1 translocates from cytosol to early endosome membrane - v84:[modifyText]
[UpdateTracker:9904860] Update Tracker - [Complex:9762081] BTRC:SKP1:CUL1:RBX1:p-S344, S347 NFE2L2 [nucleoplasm] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904983] Update Tracker - [Complex:180343] EGF-like ligands:Phospho-EGFR (-Y1016) dimer [plasma membrane] - v84:[addName, updateContainedComponent]
[UpdateTracker:9904677] Update Tracker - [Complex:8936615] H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904627] Update Tracker - [EntityWithAccessionedSequence:5689169] Ub-181-UBC(153-228) [cytosol] - v84:[modifyName]
[UpdateTracker:9904991] Update Tracker - [Complex:5084071] PRC2 Core:Chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905053] Update Tracker - [Complex:9009060] CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846649] Update Tracker - [Pathway:9679506] SARS-CoV Infections - v84:[updateIndirectRLE]
[UpdateTracker:9905002] Update Tracker - [DefinedSet:8863830] Phosphorylated p-Y877,Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 heterodimers [plasma membrane] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904582] Update Tracker - [EntityWithAccessionedSequence:2768982] NOTCH1 P2514Rfs*4 Transmembrane Fragment [plasma membrane] - v84:[add_removeHasModifiedResidue]
[UpdateTracker:9846601] Update Tracker - [Pathway:433835] IKK related kinases bound to dsRNA:TLR3:TICAM1 activate IRF3 - v84:[modifyText, updateIndirectRLE]
[UpdateTracker:9904587] Update Tracker - [Complex:5685039] ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904980] Update Tracker - [Complex:983418] COPII vesicle with MHC class I [ER to Golgi transport vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904852] Update Tracker - [EntityWithAccessionedSequence:5693124] p-S342-BCKDHB [mitochondrial matrix] - v84:[modifyName]
[UpdateTracker:9846660] Update Tracker - [Reaction:183072] EGFR non-clathrin mediated endocytosis - v84:[modifyText]
[UpdateTracker:9904803] Update Tracker - [Complex:3211727] Chromatin with acetylated H3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904749] Update Tracker - [Complex:3788746] IL8 gene:Nucleosome-H3K9Me2 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904577] Update Tracker - [EntityWithAccessionedSequence:5689185] Ub-409-UBC(381-456) [cytosol] - v84:[modifyName]
[UpdateTracker:9846814] Update Tracker - [Reaction:9759850] Foxf1 binds the Gata4 gene - v84:[modifyText]
[UpdateTracker:9904949] Update Tracker - [EntityWithAccessionedSequence:5689211] Ub-331-UBC(305-380) [cytosol] - v84:[modifyName]
[UpdateTracker:9846650] Update Tracker - [Pathway:388841] Costimulation by the CD28 family - v84:[updateIndirectRLE]
[UpdateTracker:9904687] Update Tracker - [EntityWithAccessionedSequence:5625150] SLC20A2 V195Lfs*61 [plasma membrane] - v84:[modifyName]
[UpdateTracker:9905059] Update Tracker - [Complex:9707288] K6PolyUb,p-5S-BRCA1:K6PolyUb,p-2T-BARD1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905013] Update Tracker - [EntityWithAccessionedSequence:5689182] Ub-407-UBC(381-456) [cytosol] - v84:[add_removeHasModifiedResidue, modifyName]
[UpdateTracker:9846769] Update Tracker - [Pathway:180024] DARPP-32 events - v84:[updateContainedRLE]
[UpdateTracker:9904554] Update Tracker - [EntityWithAccessionedSequence:9673609] PDGFRA Y375_K455del [endoplasmic reticulum membrane] - v84:[modifyName]
[UpdateTracker:9846801] Update Tracker - [Pathway:9675132] Diseases of cellular response to stress - v84:[updateContainedPathway]
[UpdateTracker:9846616] Update Tracker - [Reaction:111919] PKA phosphorylates CREB1 - v84:[modifyText]
[UpdateTracker:9904597] Update Tracker - [Complex:9604881] SIRT6:Nucleosome(H3K9ac):NOTCH1 gene [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904553] Update Tracker - [EntityWithAccessionedSequence:5334040] TCF7L2 K485fs*25 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846643] Update Tracker - [Reaction:2028673] Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N - v84:[modifyText]
[UpdateTracker:9904742] Update Tracker - [Complex:2272757] HLA-C Cw4/Cw3:KIR2DS4:DAP12 dimer:KIR2DS4:HLA-C Cw3/Cw4 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846714] Update Tracker - [BlackBoxEvent:9793928] Expression of Mesp2 in presomitic mesoderm - v84:[addLiteratureReference, modifyText]
[UpdateTracker:9904922] Update Tracker - [EntityWithAccessionedSequence:2902194] NEXT1 P2474Afs*4 [plasma membrane] - v84:[addLiteratureReference, add_removeHasModifiedResidue]
[UpdateTracker:9846785] Update Tracker - [BlackBoxEvent:9727305] mRNA8 is translated to protein 8 - v84:[add_removeInput]
[UpdateTracker:9846633] Update Tracker - [BlackBoxEvent:9793901] Expression of DLL3 in paraxial mesoderm - v84:[modifyText]
[UpdateTracker:9904764] Update Tracker - [EntityWithAccessionedSequence:9762202] p-Y483 BACH1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904513] Update Tracker - [Complex:203463] MHC Class II bearing antigen peptide [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905067] Update Tracker - [Complex:8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - v84:[addName]
[UpdateTracker:9905095] Update Tracker - [EntityWithAccessionedSequence:9687995] RB1 N854* [cytosol] - v84:[addName, modifyEndCoordinate]
[UpdateTracker:9904675] Update Tracker - [DefinedSet:2272698] HLA-C Cw3/HLA-C Cw4 [plasma membrane] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904442] Update Tracker - [Complex:9628212] APAF1:ATP:CYCS heptamer:p-T412-CASP9 [cytosol] - v84:[modifyName]
[UpdateTracker:9904447] Update Tracker - [EntityWithAccessionedSequence:376414] NCOA6 [nucleoplasm] - v84:[addName]
[UpdateTracker:9904509] Update Tracker - [Complex:202330] ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904974] Update Tracker - [EntityWithAccessionedSequence:9673228] F9(29-461) R43Q [extracellular region] - v84:[modifyName]
[UpdateTracker:9846750] Update Tracker - [Reaction:164124] Dephosphorylation of PF2K-Pase by rPP2A complex - v84:[modifyText]
[UpdateTracker:9904657] Update Tracker - [Complex:5625782] p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904448] Update Tracker - [EntityWithAccessionedSequence:5661066] SLC9A6 E255_S256del [early endosome membrane] - v84:[modifyName]
[UpdateTracker:9904573] Update Tracker - [EntityWithAccessionedSequence:190064] p-5Y-NTRK1-1 [endosome membrane] - v84:[add_removeHasModifiedResidue]
[UpdateTracker:9846696] Update Tracker - [BlackBoxEvent:6814554] Dephosphorylation and dissociation of RNA polymerase II at 3' end of snRNA gene - v84:[addOutput]
[UpdateTracker:9904969] Update Tracker - [Complex:5686226] Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904999] Update Tracker - [EntityWithAccessionedSequence:9630213] NTHL1 Q287* [nucleoplasm] - v84:[addHasModifiedResidue]
[UpdateTracker:9846778] Update Tracker - [Pathway:111931] PKA-mediated phosphorylation of CREB - v84:[updateContainedRLE]
[UpdateTracker:9904975] Update Tracker - [Complex:5617885] HOXC4 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904943] Update Tracker - [Complex:5686613] RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904716] Update Tracker - [Complex:2213234] TGN-lysosome vesicle with nonameric complex [trans-Golgi network membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904707] Update Tracker - [EntityWithAccessionedSequence:169869] p-Y1095-KIDINS220 [cytosol] - v84:[modifyName]
[UpdateTracker:9905050] Update Tracker - [EntityWithAccessionedSequence:71868] PXLP-p-S15-PYGB [cytosol] - v84:[modifyName]
[UpdateTracker:9904828] Update Tracker - [Complex:5617880] RARA,B:RXRA at HOXB4 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846727] Update Tracker - [Reaction:5357479] p-AXL binds PI3K - v84:[modifyText]
[UpdateTracker:9846627] Update Tracker - [Pathway:451927] Interleukin-2 family signaling - v84:[updateIndirectRLE]
[UpdateTracker:9904929] Update Tracker - [Complex:8936600] RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904546] Update Tracker - [Complex:9604879] SIRT6:Nucleosome(H3K9ac):NOTCH4 gene [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904739] Update Tracker - [Complex:5684128] 3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905033] Update Tracker - [Complex:3451134] TCF4 gene:acetyl H4 nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904930] Update Tracker - [Complex:2214375] MHC II alpha/beta dimer [Golgi membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904462] Update Tracker - [EntityWithAccessionedSequence:1369081] p-Y542-PTPN11 [cytosol] - v84:[modifyName]
[UpdateTracker:9904433] Update Tracker - [EntityWithAccessionedSequence:6783154] Ub-185-UBC(153-228) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9905078] Update Tracker - [Complex:8867035] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904867] Update Tracker - [EntityWithAccessionedSequence:167955] p-S218,T222-MAP2K3 [cytosol] - v84:[modifyName]
[UpdateTracker:9904766] Update Tracker - [Complex:5357462] VEGFA:p-6Y-VEGFR2:SH2D2A:p-Y418-SRC-1:p-Y779,Y821-AXL [plasma membrane] - v84:[modifyName]
[UpdateTracker:9904821] Update Tracker - [Complex:8865496] RUNX1:CBFB:KMT2A:SPI1 gene:H3K4me3-Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905091] Update Tracker - [Complex:937333] TAX1BP1:TNFAIP3:TBK1/IKBKE [cytosol] - v84:[addName]
[UpdateTracker:9904942] Update Tracker - [Complex:2130425] MHC class II alpha/beta/Ii nonamer [clathrin-coated endocytic vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846713] Update Tracker - [FailedReaction:9673223] FIX(29-461) variant is not activated (factor XIa catalyst) - v84:[modifyText]
[UpdateTracker:9905010] Update Tracker - [Complex:8985941] p-STAT5A,p-STAT5B dimer [cytosol] - v84:[updateContainedComponent]
[UpdateTracker:9846698] Update Tracker - [Reaction:163672] Phosphorylation of ChREBP at Thr(653) by PKA - v84:[modifyText]
[UpdateTracker:9904972] Update Tracker - [Complex:391112] p-Y428,Y452,Y469,Y495-SIRPA:CD47:GRB2-1 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846593] Update Tracker - [Pathway:388396] GPCR downstream signalling - v84:[updateIndirectRLE]
[UpdateTracker:9905014] Update Tracker - [Complex:5685983] 3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904904] Update Tracker - [DefinedSet:8866252] ubiquitinated cargo [plasma membrane] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904902] Update Tracker - [Complex:8986971] IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904689] Update Tracker - [DefinedSet:8943141] K48polyUb-HLA A-2,A-3,B-60 [endoplasmic reticulum membrane] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9846724] Update Tracker - [Pathway:5357956] TNFR1-induced NF-kappa-B signaling pathway - v84:[updateContainedRLE]
[UpdateTracker:9904820] Update Tracker - [EntityWithAccessionedSequence:5357460] p-Y779,Y821-AXL [plasma membrane] - v84:[modifyName]
[UpdateTracker:9904832] Update Tracker - [Complex:8937048] H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904457] Update Tracker - [Complex:427510] eNoSC [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904966] Update Tracker - [Complex:9011905] MYC gene, BCL2 gene: H3K9me2 nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846753] Update Tracker - [Reaction:1225960] Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants - v84:[modifyText]
[UpdateTracker:9904708] Update Tracker - [EntityWithAccessionedSequence:6782637] Ub-559-UBC(533-608) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904530] Update Tracker - [Complex:5617671] MAFB:JUN and EGR2 at active HOXB3 chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904691] Update Tracker - [EntityWithAccessionedSequence:5689136] Ub-637-UBC(609-684) [cytosol] - v84:[modifyName]
[UpdateTracker:9846613] Update Tracker - [Reaction:6786205] KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 - v84:[modifyText]
[UpdateTracker:9904948] Update Tracker - [Complex:3364034] MYC gene:H2B K121ub H3K4me3 nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905020] Update Tracker - [Complex:983419] monoglucosylated MHC class I HC [ER to Golgi transport vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904754] Update Tracker - [EntityWithAccessionedSequence:198721] p-T218,Y221-MAPK7 [cytosol] - v84:[modifyName]
[UpdateTracker:9905047] Update Tracker - [DefinedSet:983117] Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[removeHasMember]
[UpdateTracker:9905046] Update Tracker - [Complex:182960] EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane] - v84:[addName]
[UpdateTracker:9904477] Update Tracker - [Complex:9018569] EGF:p-6Y-EGFR dimer:NICD3 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904683] Update Tracker - [EntityWithAccessionedSequence:5689152] Ub-337-UBC(305-380) [cytosol] - v84:[modifyName]
[UpdateTracker:9846747] Update Tracker - [Reaction:9793837] TBX6 binds the MESP2 gene - v84:[modifyText]
[UpdateTracker:9904939] Update Tracker - [EntityWithAccessionedSequence:162472] p-S950,S951-LIPE [cytosol] - v84:[modifyName]
[UpdateTracker:9904795] Update Tracker - [Complex:8864018] EGF:p-Y1016,Y1069,Y1092,Y1110,Y1197-EGFR [plasma membrane] - v84:[addName]
[UpdateTracker:9846749] Update Tracker - [Pathway:5693565] Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks - v84:[updateContainedRLE]
[UpdateTracker:9846672] Update Tracker - [Pathway:194138] Signaling by VEGF - v84:[updateIndirectRLE]
[UpdateTracker:9904776] Update Tracker - [Complex:8865490] RUNX1:CBFB:KMT2A:SPI1 gene:Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904602] Update Tracker - [Complex:8868634] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846671] Update Tracker - [Reaction:164056] Dephosphorylation of pChREBP (Ser 556) by PP2A - v84:[modifyText]
[UpdateTracker:9904833] Update Tracker - [Complex:181921] Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904781] Update Tracker - [EntityWithAccessionedSequence:6783172] Ub-561-UBC(533-608) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904936] Update Tracker - [Complex:8964231] G protein alpha (i):GTP:p-Y419-SRC [plasma membrane] - v84:[modifyName]
[UpdateTracker:9904681] Update Tracker - [Complex:9011925] GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905035] Update Tracker - [Complex:5334159] DNMT3A:DNMT3L:Chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904857] Update Tracker - [EntityWithAccessionedSequence:6783032] Ub-103-UBC(77-152) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904859] Update Tracker - [Complex:5625791] Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846770] Update Tracker - [Reaction:9685830] TUBB binds colchicine - v84:[modifyText]
[UpdateTracker:9846742] Update Tracker - [Reaction:8964252] G alpha (s):GTP:SRC catalyzes SRC to p-Y419-SRC - v84:[modifyText]
[UpdateTracker:9904876] Update Tracker - [Complex:9662709] p-S133-CREB1:IL6 gene [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846760] Update Tracker - [Polymerisation:2160851] HAS1,2,3 mediate the polymerization of HA - v84:[modifyText]
[UpdateTracker:9905000] Update Tracker - [Complex:182932] EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] - v84:[addName, updateContainedComponent]
[UpdateTracker:9846628] Update Tracker - [FailedReaction:5637794] EGFRvIII does not bind CBL - v84:[modifyText]
[UpdateTracker:9904483] Update Tracker - [Complex:8937112] RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904721] Update Tracker - [Complex:5684874] ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904432] Update Tracker - [Complex:199585] HLA-C group 2 interacting with KIR2DS1 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904786] Update Tracker - [Complex:2272727] DAP12:KIR2DS1:HLA-Cw4 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905021] Update Tracker - [CandidateSet:9762061] p-S344, 347 NFE2L2 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904603] Update Tracker - [Complex:8951502] 2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904865] Update Tracker - [CandidateSet:9007110] p-Y-STAT3,p-STAT5,(p-Y-STAT3:p-STAT5) [cytosol] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904609] Update Tracker - [Complex:5617465] RARA,G:RXRA at HOXA1 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904496] Update Tracker - [EntityWithAccessionedSequence:2685625] p-S559,S652-CARD11 [cytosol] - v84:[modifyName]
[UpdateTracker:9904684] Update Tracker - [EntityWithAccessionedSequence:5689140] Ub-185-UBC(153-228) [cytosol] - v84:[modifyName]
[UpdateTracker:9904988] Update Tracker - [EntityWithAccessionedSequence:6782638] Ub-333-UBC(305-380) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905101] Update Tracker - [EntityWithAccessionedSequence:9647492] NF1 I1009Ffs*3 [cytosol] - v84:[addHasModifiedResidue, modifyEndCoordinate, modifyName]
[UpdateTracker:9904450] Update Tracker - [Complex:388795] p-Y201,Y218-CTLA-4 dimer:SFKs [plasma membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904545] Update Tracker - [EntityWithAccessionedSequence:6783028] Ub-261-UBC(229-304) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904760] Update Tracker - [Complex:2213223] peptide loaded MHC class II [lysosomal membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846805] Update Tracker - [Reaction:8876889] Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA - v84:[modifyText]
[UpdateTracker:9904733] Update Tracker - [DefinedSet:202282] ZAP-70 and ITK tyrosine kinases [plasma membrane] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904862] Update Tracker - [EntityWithAccessionedSequence:9687335] p-T252-RB1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904955] Update Tracker - [Complex:2213189] MHC class II alpha/beta dimer [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905055] Update Tracker - [Complex:202266] Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905065] Update Tracker - [Complex:8867751] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904538] Update Tracker - [DefinedSet:9707287] p-S1387,S1423,S1457,S1524-BRCA1:p-T714,T734-BARD1 [nucleoplasm] - v84:[modifyName, updateContainedMemberOrCandidate]
[UpdateTracker:9904908] Update Tracker - [Complex:983420] monoglucosylated MHC class I HC [Golgi membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904968] Update Tracker - [Complex:8878069] p-S249,S273,S276-RUNX1:CBFB [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846654] Update Tracker - [Pathway:9755511] KEAP1-NFE2L2 pathway - v84:[updateIndirectRLE]
[UpdateTracker:9846701] Update Tracker - [Pathway:9662851] Anti-inflammatory response favouring Leishmania parasite infection - v84:[updateIndirectRLE]
[UpdateTracker:9846798] Update Tracker - [Pathway:9006934] Signaling by Receptor Tyrosine Kinases - v84:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904931] Update Tracker - [EntityWithAccessionedSequence:9699812] EML4(1-496)-ALK(1058-1620) fusion [cytosol] - v84:[modifyName]
[UpdateTracker:9904475] Update Tracker - [Complex:5686432] Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904885] Update Tracker - [Complex:8856203] LAG3:MHC II [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905081] Update Tracker - [Complex:9031611] p-S133-CREB1:MEF2D:SRF:ARC gene [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904473] Update Tracker - [Complex:9629403] NEIL3:Sp-Telomeric DNA:Shelterin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904644] Update Tracker - [EntityWithAccessionedSequence:2902204] p-NICD1 P2474Afs*4 [nucleoplasm] - v84:[addLiteratureReference, add_removeHasModifiedResidue]
[UpdateTracker:9904723] Update Tracker - [Complex:3211699] DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904662] Update Tracker - [EntityWithAccessionedSequence:9647519] NF1 R304Q [cytosol] - v84:[addHasModifiedResidue, modifyEndCoordinate]
[UpdateTracker:9904878] Update Tracker - [Complex:9709610] 3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:BRCA2 mutants (PALB2 binding):SEM1:BCDX2 complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904541] Update Tracker - [EntityWithAccessionedSequence:5689139] Ub-103-UBB(77-152) [cytosol] - v84:[modifyName]
[UpdateTracker:9904437] Update Tracker - [EntityWithAccessionedSequence:5689220] Ub-483-UBC(457-532) [cytosol] - v84:[modifyName]
[UpdateTracker:9904712] Update Tracker - [Complex:5685655] BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904664] Update Tracker - [Complex:5617489] EGR2 at active HOXB2 chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905068] Update Tracker - [EntityWithAccessionedSequence:535610] CXXC1 [nucleoplasm] - v84:[addName]
[UpdateTracker:9846761] Update Tracker - [Pathway:75105] Fatty acyl-CoA biosynthesis - v84:[updateContainedRLE]
[UpdateTracker:9904690] Update Tracker - [Complex:1236928] Class I MHC HC:B2M [phagocytic vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904802] Update Tracker - [Complex:9749196] H4K20Me2-nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904670] Update Tracker - [EntityWithAccessionedSequence:6782630] Ub-331-UBC(305-380) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904463] Update Tracker - [EntityWithAccessionedSequence:6783156] Ub-483-UBC(457-532) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9905085] Update Tracker - [Complex:8985997] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904572] Update Tracker - [EntityWithAccessionedSequence:6783149] Ub-103-UBB(77-152) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9846812] Update Tracker - [Pathway:1643685] Disease - v84:[updateContainedPathway]
[UpdateTracker:9846645] Update Tracker - [Reaction:163689] Dephosphorylation of pChREBP (Ser 196) by PP2A - v84:[modifyText]
[UpdateTracker:9905087] Update Tracker - [Complex:8865492] SPI1 gene:Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904559] Update Tracker - [Complex:6810166] HOXB2 active chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904499] Update Tracker - [EntityWithAccessionedSequence:162487] p-S959,S960-Lipe [cytosol] - v84:[modifyName]
[UpdateTracker:9905075] Update Tracker - [Complex:9013981] activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904428] Update Tracker - [Complex:198904] Antigen peptide bound class I MHC [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904729] Update Tracker - [EntityWithAccessionedSequence:6783107] Ub-179-UBC(153-228) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9846686] Update Tracker - [Pathway:74160] Gene expression (Transcription) - v84:[updateContainedPathway]
[UpdateTracker:9846758] Update Tracker - [Pathway:200425] Carnitine metabolism - v84:[updateContainedRLE]
[UpdateTracker:9904552] Update Tracker - [Complex:5686493] Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904446] Update Tracker - [Complex:5617453] HOXD1 active chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904626] Update Tracker - [Complex:3211676] Chromatin with hemimethylC, H3K27me3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846777] Update Tracker - [Pathway:68886] M Phase - v84:[updateIndirectRLE]
[UpdateTracker:9904659] Update Tracker - [Complex:9613448] ID1,ID3 genes:p-S133-CREB1:LYL1:EP300 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904571] Update Tracker - [EntityWithAccessionedSequence:6783158] Ub-109-UBC(77-152) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9846765] Update Tracker - [BlackBoxEvent:9727292] mRNA6 is translated to protein 6 - v84:[add_removeInput]
[UpdateTracker:9846787] Update Tracker - [Pathway:9705671] SARS-CoV-2 activates/modulates innate and adaptive immune responses - v84:[updateContainedRLE]
[UpdateTracker:9904656] Update Tracker - [Complex:9615489] p-S133-CREB1:MIR132 gene [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846684] Update Tracker - [Pathway:9634600] Regulation of glycolysis by fructose 2,6-bisphosphate metabolism - v84:[updateContainedRLE]
[UpdateTracker:9905030] Update Tracker - [Complex:5226877] Chromatin with H3K9me2, 5mC [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846644] Update Tracker - [Pathway:5693606] DNA Double Strand Break Response - v84:[updateIndirectRLE]
[UpdateTracker:9846817] Update Tracker - [Pathway:212165] Epigenetic regulation of gene expression - v84:[addHasEvent, addLiteratureReference, modifyText]
[UpdateTracker:9904465] Update Tracker - [SimpleEntity:77502] AdoHcy [nucleoplasm] - v84:[add_removeReferenceEntity]
[UpdateTracker:9904663] Update Tracker - [CandidateSet:8857936] Activated SRC,LCK,EGFR,INSR [plasma membrane] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904727] Update Tracker - [Complex:9021896] MECP2:p-S133-CREB1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904957] Update Tracker - [Complex:5625789] p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846639] Update Tracker - [Reaction:177943] GRB2:SOS1 complex binds to EGF:EGFR complex - v84:[modifyText]
[UpdateTracker:9904564] Update Tracker - [EntityWithAccessionedSequence:5685740] p-S738,T744 SEC23A [cytosol] - v84:[modifyName]
[UpdateTracker:9904510] Update Tracker - [EntityWithAccessionedSequence:6783160] Ub-181-UBB(153-228) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9846605] Update Tracker - [Pathway:9758941] Gastrulation - v84:[addHasEvent, updateIndirectRLE]
[UpdateTracker:9904547] Update Tracker - [Complex:8936977] H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904917] Update Tracker - [EntityWithAccessionedSequence:6783097] Ub-181-UBC(153-228) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904903] Update Tracker - [Complex:2272773] KIR2DS1 oligomer:HLA-C (Cw4) [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904493] Update Tracker - [Complex:5659852] p-S1387,S1423,S1457,S1524-BRCA1:p-T714,T734-BARD1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905069] Update Tracker - [Complex:9629206] NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905032] Update Tracker - [Complex:9707296] K6PolyUb,p-5S-BRCA1:K6PolyUb,p-2T-BARD1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846667] Update Tracker - [Pathway:8978868] Fatty acid metabolism - v84:[updateIndirectRLE]
[UpdateTracker:9904925] Update Tracker - [Complex:182931] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:SPRY1/2:Endophilin:Epsin:Eps15L1:EPS15 [plasma membrane] - v84:[addName, updateContainedComponent]
[UpdateTracker:9904468] Update Tracker - [Complex:2213179] MHC II alpha/beta dimer [lysosomal membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904982] Update Tracker - [Complex:9015116] Va:Xa:Factor Xa inhibitors [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846748] Update Tracker - [Pathway:9673221] Defective F9 activation - v84:[updateContainedRLE]
[UpdateTracker:9904933] Update Tracker - [EntityWithAccessionedSequence:5689218] Ub-641-UBC(609-684) [cytosol] - v84:[modifyName]
[UpdateTracker:9904924] Update Tracker - [EntityWithAccessionedSequence:6782642] Ub-409-UBC(381-456) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905071] Update Tracker - [EntityWithAccessionedSequence:5689196] Ub-109-UBC(77-152) [cytosol] - v84:[modifyName]
[UpdateTracker:9905003] Update Tracker - [CandidateSet:5218310] Me2sR4-histone H2A [nucleoplasm] - v84:[removeHasCandidate]
[UpdateTracker:9846668] Update Tracker - [Reaction:9793680] OPTN binds polyUb-RIPK1 within the TNFR1 complex - v84:[addLiteratureReference, add_removeSummation]
[UpdateTracker:9904745] Update Tracker - [Complex:182961] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] - v84:[addName, updateContainedComponent]
[UpdateTracker:9904598] Update Tracker - [Complex:5621009] HOXB1:PBX1:MEIS1,PKNOX1 at active HOXB2 chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846803] Update Tracker - [Pathway:9762114] GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 - v84:[updateContainedRLE]
[UpdateTracker:9846699] Update Tracker - [Pathway:5687128] MAPK6/MAPK4 signaling - v84:[updateContainedRLE]
[UpdateTracker:9846809] Update Tracker - [Pathway:9031628] NGF-stimulated transcription - v84:[updateContainedRLE]
[UpdateTracker:9904539] Update Tracker - [Complex:5334110] DNMT3B:DNMT3L:Chromatin with 5mC [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904767] Update Tracker - [Complex:2272706] KIR2DS4:HLA-C Cw4/HLA-C Cw3 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904722] Update Tracker - [EntityWithAccessionedSequence:6782672] Ub-561-UBC(533-608) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904639] Update Tracker - [Complex:140662] FVa:FXa [plasma membrane] - v84:[addName]
[UpdateTracker:9904926] Update Tracker - [EntityWithAccessionedSequence:6782650] Ub-483-UBC(457-532) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904788] Update Tracker - [Complex:388794] p-Y201,Y218-CTLA-4 dimer [plasma membrane] - v84:[modifyName]
[UpdateTracker:9846597] Update Tracker - [Pathway:8985947] Interleukin-9 signaling - v84:[updateContainedRLE]
[UpdateTracker:9905073] Update Tracker - [Complex:8943093] US11:HLA:TMEM129:DERL1:VIMP:VCP:Ub:UBE2J2 [endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846656] Update Tracker - [Pathway:163358] PKA-mediated phosphorylation of key metabolic factors - v84:[updateContainedRLE]
[UpdateTracker:9904650] Update Tracker - [Complex:5686104] Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904882] Update Tracker - [EntityWithAccessionedSequence:6783199] Ub-333-UBC(305-380) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904519] Update Tracker - [Complex:198896] MHC Class I interacting with LILRs [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846810] Update Tracker - [Reaction:163691] Phosphorylation of ChREBP at Serine 556 by AMPK - v84:[modifyText]
[UpdateTracker:9846762] Update Tracker - [Pathway:5357905] Regulation of TNFR1 signaling - v84:[addHasEvent, updateContainedRLE]
[UpdateTracker:9904436] Update Tracker - [Complex:8937114] RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904986] Update Tracker - [Complex:2130309] Clathrin coated MHC class II alpha/beta/Ii nonamer [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846781] Update Tracker - [Pathway:72163] mRNA Splicing - Major Pathway - v84:[modifyText]
[UpdateTracker:9904736] Update Tracker - [Complex:2130574] MHC II:CLIP [lysosomal membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846705] Update Tracker - [Pathway:5686938] Regulation of TLR by endogenous ligand - v84:[modifyText]
[UpdateTracker:9846788] Update Tracker - [BlackBoxEvent:8985900] p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 - v84:[modifyText]
[UpdateTracker:9904589] Update Tracker - [Complex:9670122] Telomere:Shelterin:Nucleosome (H3F3A):ATRX:DAXX [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904921] Update Tracker - [Complex:5617861] atRA:RARA,B:RXRA at active HOXD4 chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904961] Update Tracker - [Complex:199562] HLA-C Cw3 (group 1) [plasma membrane] - v84:[add_removeHasComponent]
[UpdateTracker:9846715] Update Tracker - [Reaction:202437] Phosphorylation of CARMA1 - v84:[addLiteratureReference, modifyText]
[UpdateTracker:9904652] Update Tracker - [Complex:5686617] p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904759] Update Tracker - [Complex:199567] HLA-Bw4 [plasma membrane] - v84:[add_removeHasComponent]
[UpdateTracker:9904718] Update Tracker - [Complex:199560] HLA-C group 2 interacting with KIR2DL1 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904578] Update Tracker - [Complex:8943114] US11:HLA [endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904967] Update Tracker - [Complex:182945] EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane] - v84:[addName]
[UpdateTracker:9904476] Update Tracker - [Complex:390339] Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904807] Update Tracker - [Complex:8868232] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905044] Update Tracker - [Complex:2172686] PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846636] Update Tracker - [Reaction:8864029] PTPN12 dephosphorylates EGFR at Y1172 (Y1148) - v84:[modifyText]
[UpdateTracker:9905099] Update Tracker - [Complex:9674551] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:p-Y-STAT1,3,5 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905028] Update Tracker - [CandidateSet:8983121] p-Y694-STAT5A, p-STAT5B [cytosol] - v84:[modifyName]
[UpdateTracker:9846784] Update Tracker - [Pathway:442720] CREB1 phosphorylation through the activation of Adenylate Cyclase - v84:[updateContainedRLE]
[UpdateTracker:9904525] Update Tracker - [Complex:8863834] EGF:p-Y992,Y1045,Y1068,Y1086,Y1173-EGFR:p-Y877,Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904844] Update Tracker - [Complex:3229098] CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904474] Update Tracker - [EntityWithAccessionedSequence:198738] p-T218,Y221-MAPK7 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905054] Update Tracker - [EntityWithAccessionedSequence:9673213] F9(29-461) R43W [extracellular region] - v84:[modifyName]
[UpdateTracker:9904726] Update Tracker - [Complex:6810133] HOXA2 active chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904836] Update Tracker - [Complex:8987029] IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1, p-Y-STAT2, p-STAT3 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904604] Update Tracker - [EntityWithAccessionedSequence:5689221] Ub-179-UBC(153-228) [cytosol] - v84:[modifyName]
[UpdateTracker:9904492] Update Tracker - [Complex:5625874] p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846775] Update Tracker - [Reaction:434030] TBK1 is recruited to the Viral dsRNA:TLR3:TICAM1 complex - v84:[modifyText]
[UpdateTracker:9904661] Update Tracker - [EntityWithAccessionedSequence:163467] p-S950,S951-LIPE [lipid droplet] - v84:[modifyName]
[UpdateTracker:9846706] Update Tracker - [Pathway:166208] mTORC1-mediated signalling - v84:[updateContainedRLE]
[UpdateTracker:9904455] Update Tracker - [EntityWithAccessionedSequence:6783004] Ub-255-UBC(229-304) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9846681] Update Tracker - [Pathway:450728] Inhibition of actin polymerization - v84:[updateContainedRLE]
[UpdateTracker:9904937] Update Tracker - [Complex:983127] Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904756] Update Tracker - [DefinedSet:1236901] Class I MHC heavy chain (MHC HC) [early endosome membrane] - v84:[removeHasMember]
[UpdateTracker:9846655] Update Tracker - [Reaction:163750] Dephosphorylation of phosphoPFKFB1 by PP2A complex - v84:[modifyText]
[UpdateTracker:9904646] Update Tracker - [Complex:983414] COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904585] Update Tracker - [Complex:5625760] Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905086] Update Tracker - [DefinedSet:983408] Class I MHC heavy chain (MHC HC) [ER to Golgi transport vesicle membrane] - v84:[removeHasMember]
[UpdateTracker:9904774] Update Tracker - [EntityWithAccessionedSequence:5689189] Ub-103-UBC(77-152) [cytosol] - v84:[modifyName]
[UpdateTracker:9846622] Update Tracker - [Reaction:433804] IKK epsilon is recruited to the Viral dsRNA:TLR3:TICAM1 complex - v84:[modifyText]
[UpdateTracker:9904829] Update Tracker - [EntityWithAccessionedSequence:5689150] Ub-261-UBC(229-304) [cytosol] - v84:[modifyName]
[UpdateTracker:9905019] Update Tracker - [EntityWithAccessionedSequence:2028551] p-S909,T1079-LATS1 [cytosol] - v84:[modifyName]
[UpdateTracker:9904798] Update Tracker - [CandidateSet:189046] alpha-amylase [extracellular region] - v84:[add_removeHasCandidate]
[UpdateTracker:9846629] Update Tracker - [Pathway:70326] Glucose metabolism - v84:[updateIndirectRLE]
[UpdateTracker:9904738] Update Tracker - [Complex:5617470] atRA:RARA,G:RXRA at active HOXB1 chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904861] Update Tracker - [Complex:391118] p-Y429,Y453,Y470,Y496-SIRPA:CD47:SKAP2 [plasma membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9846651] Update Tracker - [Pathway:2514856] The phototransduction cascade - v84:[updateIndirectRLE]
[UpdateTracker:9904775] Update Tracker - [EntityWithAccessionedSequence:6783016] Ub-257-UBC(229-304) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904928] Update Tracker - [EntityWithAccessionedSequence:9647532] NF1 R2517* [cytosol] - v84:[addHasModifiedResidue]
[UpdateTracker:9904622] Update Tracker - [Complex:2130467] MHC class II alpha/beta/Ii nonamer [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904498] Update Tracker - [Complex:3211702] PRC2:Chromatin (5-methylcytosine, H3K27me3) [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904822] Update Tracker - [EntityWithAccessionedSequence:9656288] OGG1 P266fs*139 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904494] Update Tracker - [EntityWithAccessionedSequence:428468] Pak [cytosol] - v84:[add_removeReferenceEntity]
[UpdateTracker:9904787] Update Tracker - [Complex:198909] HLA-C group 1 interacting with KIR2DL2/3 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904655] Update Tracker - [Complex:5685343] 3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846738] Update Tracker - [Pathway:199920] CREB phosphorylation - v84:[updateContainedRLE]
[UpdateTracker:9904910] Update Tracker - [Complex:9011911] KDM4B-regulated genes:nucleosome:ESR1:ESTG [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846818] Update Tracker - [BlackBoxEvent:9793933] Expression of MESP2 in presomitic mesoderm - v84:[modifyText]
[UpdateTracker:9904940] Update Tracker - [DefinedSet:6800420] Secretory granule membrane proteins [secretory granule membrane] - v84:[removeHasMember]
[UpdateTracker:9904728] Update Tracker - [EntityWithAccessionedSequence:9818793] K63,Met1polyUb-p-S25-RIPK1 [cytosol] - v84:[modifyName]
[UpdateTracker:9904673] Update Tracker - [EntityWithAccessionedSequence:6814543] p-S2,S7(CTD)-POLR2A [nucleoplasm] - v84:[addHasModifiedResidue, modifyName]
[UpdateTracker:9904454] Update Tracker - [EntityWithAccessionedSequence:6782678] Ub-181-UBC(153-228) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905008] Update Tracker - [Complex:8951497] AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904558] Update Tracker - [DefinedSet:2130672] HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[removeHasMember]
[UpdateTracker:9904879] Update Tracker - [DefinedSet:1236902] Class I MHC heavy chain (MHC HC) [phagocytic vesicle membrane] - v84:[removeHasMember]
[UpdateTracker:9904868] Update Tracker - [Complex:5685656] BRCA1-C complex [nucleoplasm] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904715] Update Tracker - [Complex:5684053] DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:SUMO2:K1840,p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-5S,2T-BRCA1-A complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904701] Update Tracker - [Complex:9629451] NEIL3:Tg-Telomeric DNA:Shelterin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846712] Update Tracker - [Reaction:9762093] BTRC binds p-S344, 347 NFE2L2 - v84:[modifyText]
[UpdateTracker:9905012] Update Tracker - [Complex:5617888] atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905079] Update Tracker - [Complex:9749192] ORC1:H4K20Me2-nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904848] Update Tracker - [Complex:3211683] Chromatin (H3K9me2) [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904529] Update Tracker - [Complex:182275] class I MHC complex [Golgi membrane] - v84:[add_removeHasComponent]
[UpdateTracker:9904434] Update Tracker - [EntityWithAccessionedSequence:162573] p-Y542,Y580-PTPN11 [cytosol] - v84:[modifyName]
[UpdateTracker:9904569] Update Tracker - [EntityWithAccessionedSequence:3928368] p-Y606,Y612-EPHA6 [plasma membrane] - v84:[modifyName]
[UpdateTracker:9846641] Update Tracker - [Pathway:2682334] EPH-Ephrin signaling - v84:[updateIndirectRLE]
[UpdateTracker:9905064] Update Tracker - [Complex:2294591] p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904998] Update Tracker - [CandidateSet:199614] MHC Class I molecules interacting with CD160 [plasma membrane] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904915] Update Tracker - [Complex:937070] activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904894] Update Tracker - [Complex:3211710] Chromatin with trimethylated H3K27 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904618] Update Tracker - [Complex:179882] EGF:p-6Y-EGFR dimer [plasma membrane] - v84:[addName]
[UpdateTracker:9904631] Update Tracker - [EntityWithAccessionedSequence:5689191] Ub-105-UBB(77-152) [cytosol] - v84:[modifyName]
[UpdateTracker:9846615] Update Tracker - [Pathway:9630747] Diseases of Cellular Senescence - v84:[addLiteratureReference, modifyText]
[UpdateTracker:9904647] Update Tracker - [Complex:8867753] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904522] Update Tracker - [Complex:3364032] Nucleosome with H2BK121ub [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904724] Update Tracker - [Complex:9670121] Nucleosome (H3F3A) [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904643] Update Tracker - [EntityWithAccessionedSequence:5689167] Ub-257-UBC(229-304) [cytosol] - v84:[modifyName]
[UpdateTracker:9904734] Update Tracker - [DefinedSet:8941311] TUT4,TUT7 [cytosol] - v84:[modifyName]
[UpdateTracker:9846683] Update Tracker - [Pathway:429947] Deadenylation of mRNA - v84:[updateContainedRLE]
[UpdateTracker:9905052] Update Tracker - [Complex:8868632] PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904588] Update Tracker - [EntityWithAccessionedSequence:9723870] ALK H224_G318del [plasma membrane] - v84:[modifyName]
[UpdateTracker:9904630] Update Tracker - [Complex:9617243] CEBPB gene:p-S133-CREB1 dimer [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904692] Update Tracker - [EntityWithAccessionedSequence:6782627] Ub-103-UBB(77-152) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846703] Update Tracker - [Pathway:9664323] FCGR3A-mediated IL10 synthesis - v84:[updateContainedRLE]
[UpdateTracker:9904996] Update Tracker - [EntityWithAccessionedSequence:6782681] Ub-407-UBC(381-456) [nucleoplasm] - v84:[add_removeHasModifiedResidue, modifyName]
[UpdateTracker:9904628] Update Tracker - [EntityWithAccessionedSequence:113420] p-S2,S5(CTD)-POLR2A [nucleoplasm] - v84:[addHasModifiedResidue, modifyName]
[UpdateTracker:9904965] Update Tracker - [Complex:983116] monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846642] Update Tracker - [Reaction:450770] MWH binds to RHO1:GTP and is activated - v84:[modifyText]
[UpdateTracker:9904590] Update Tracker - [Complex:2213181] MHC II alpha/beta dimer [ER to Golgi transport vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904892] Update Tracker - [DefinedSet:2130321] HLA II beta chain [transport vesicle membrane] - v84:[removeHasMember]
[UpdateTracker:9904735] Update Tracker - [Complex:5617651] MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904610] Update Tracker - [DefinedSet:167984] p-S218,T222-MAP2K3, p-S207,T211-MAP2K6 [cytosol] - v84:[modifyName]
[UpdateTracker:9904791] Update Tracker - [EntityWithAccessionedSequence:6782665] Ub-181-UBB(153-228) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904642] Update Tracker - [Complex:9817389] TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] - v84:[add_removeHasComponent]
[UpdateTracker:9905090] Update Tracker - [EntityWithAccessionedSequence:6782661] Ub-485-UBC(457-532) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905072] Update Tracker - [Complex:8868629] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905004] Update Tracker - [Complex:433760] Nucleosome (H3K9ac, H3K14ac) [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904469] Update Tracker - [EntityWithAccessionedSequence:9016706] Me3K116-CALM1 [cytosol] - v84:[modifyName]
[UpdateTracker:9904596] Update Tracker - [DefinedSet:198889] MHC Class I [plasma membrane] - v84:[removeHasMember]
[UpdateTracker:9904645] Update Tracker - [Complex:606323] CCAN:DNA:CASC5:Centromeric nucleosome:RSF complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904503] Update Tracker - [Complex:182930] EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL [plasma membrane] - v84:[addName]
[UpdateTracker:9846623] Update Tracker - [Reaction:166271] IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 - v84:[modifyText]
[UpdateTracker:9846774] Update Tracker - [Pathway:3928662] EPHB-mediated forward signaling - v84:[updateContainedRLE]
[UpdateTracker:9846659] Update Tracker - [Pathway:450799] RHO1 signalling - v84:[updateIndirectRLE]
[UpdateTracker:9905097] Update Tracker - [EntityWithAccessionedSequence:8864019] p-Y1016,Y1069,Y1092,Y1110,Y1197-EGFR [plasma membrane] - v84:[addName]
[UpdateTracker:9904703] Update Tracker - [EntityWithAccessionedSequence:6782680] Ub-637-UBC(609-684) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904941] Update Tracker - [EntityWithAccessionedSequence:379806] p-S133-Creb1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905083] Update Tracker - [EntityWithAccessionedSequence:6783182] Ub-641-UBC(609-684) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9905027] Update Tracker - [EntityWithAccessionedSequence:6782617] Ub-185-UBC(153-228) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904431] Update Tracker - [DefinedSet:9604877] SIRT6:Nucleosome(H3K9ac):NOTCH1,NOTCH4 gene [nucleoplasm] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904979] Update Tracker - [EntityWithAccessionedSequence:165714] p-T412-RPS6KB1 [cytosol] - v84:[modifyName, removeHasModifiedResidue]
[UpdateTracker:9905005] Update Tracker - [Complex:8867034] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905106] Update Tracker - [Complex:9629210] NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846726] Update Tracker - [Pathway:937061] TRIF(TICAM1)-mediated TLR4 signaling - v84:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904608] Update Tracker - [EntityWithAccessionedSequence:5689135] Ub-255-UBC(229-304) [cytosol] - v84:[modifyName]
[UpdateTracker:9904502] Update Tracker - [Complex:1236930] Class I MHC:B2M [early endosome membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904871] Update Tracker - [Complex:5617448] atRA:RARA,G:RXRA at active HOXA1 chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846697] Update Tracker - [Pathway:8939243] RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known - v84:[updateContainedRLE]
[UpdateTracker:9905082] Update Tracker - [EntityWithAccessionedSequence:9619871] p-S221,T459,S363,S380,T573,S732-RPS6KA1 [cytosol] - v84:[modifyName]
[UpdateTracker:9904612] Update Tracker - [EntityWithAccessionedSequence:6783121] Ub-337-UBC(305-380) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904556] Update Tracker - [EntityWithAccessionedSequence:6783194] Ub-485-UBC(457-532) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9905060] Update Tracker - [Complex:427344] Chromatin (H3K9me2):CBX3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904825] Update Tracker - [Complex:8987110] IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:p-STAT1, p-STAT3 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905093] Update Tracker - [DefinedSet:983410] Class I MHC heavy chain (MHC HC) [Golgi membrane] - v84:[removeHasMember]
[UpdateTracker:9846780] Update Tracker - [Reaction:2028555] Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) - v84:[modifyText]
[UpdateTracker:9904452] Update Tracker - [Complex:5226874] Chromatin (H4K5ac, H4K8ac, H4K16ac) [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846675] Update Tracker - [Pathway:5637815] Signaling by Ligand-Responsive EGFR Variants in Cancer - v84:[updateIndirectRLE]
[UpdateTracker:9846662] Update Tracker - [Pathway:75893] TNF signaling - v84:[modifyText, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904897] Update Tracker - [Complex:8980062] 2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846786] Update Tracker - [Pathway:2454202] Fc epsilon receptor (FCERI) signaling - v84:[updateContainedRLE]
[UpdateTracker:9905025] Update Tracker - [Complex:9817409] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] - v84:[add_removeHasComponent]
[UpdateTracker:9904963] Update Tracker - [Complex:2172681] PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904964] Update Tracker - [Complex:8987211] IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904992] Update Tracker - [SimpleEntity:3296430] Aristolochic acid [extracellular region] - v84:[addName]
[UpdateTracker:9905015] Update Tracker - [Complex:9755322] 8:class I MHC:BECN1 complex [endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905034] Update Tracker - [Complex:983121] MHC:B2M peptide loading complex [endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904797] Update Tracker - [Complex:433757] Nucleosome with H3K27me3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904563] Update Tracker - [Complex:3222570] CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904863] Update Tracker - [EntityWithAccessionedSequence:165762] p-S1108,S1148,S1192-EIF4G1 [cytosol] - v84:[addLiteratureReference, addSummation]
[UpdateTracker:9904847] Update Tracker - [DefinedSet:8863991] Phosphorylated p-Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 heterodimers [plasma membrane] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9904758] Update Tracker - [Complex:8866253] EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904580] Update Tracker - [Complex:182373] Nef:class I MHC complex:Ap-1:PACS-1 Complex [Golgi membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904783] Update Tracker - [Complex:3211731] PRC2:Chromatin (H3K27me3) [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904506] Update Tracker - [Complex:3788744] IL6 gene:Nucleosome-H3K9Me2 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904679] Update Tracker - [EntityWithAccessionedSequence:6781855] Ub,p-S2,S5(CTD)-POLR2A [nucleoplasm] - v84:[addHasModifiedResidue, modifyName]
[UpdateTracker:9904672] Update Tracker - [Complex:5685658] D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846796] Update Tracker - [Pathway:180336] SHC1 events in EGFR signaling - v84:[updateContainedRLE]
[UpdateTracker:9905084] Update Tracker - [EntityWithAccessionedSequence:6783061] Ub-413-UBC(381-456) [mitochondrial outer membrane] - v84:[modifyName]
[UpdateTracker:9904565] Update Tracker - [EntityWithAccessionedSequence:9704820] PALB2 A995Cfs*16 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904460] Update Tracker - [Complex:182953] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL [plasma membrane] - v84:[addName]
[UpdateTracker:9904792] Update Tracker - [Complex:2130552] AP-1 Clathrin coated nonameric complex [trans-Golgi network membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904440] Update Tracker - [Complex:182946] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] - v84:[addName]
[UpdateTracker:9846709] Update Tracker - [Pathway:4419969] Depolymerization of the Nuclear Lamina - v84:[modifyText]
[UpdateTracker:9846744] Update Tracker - [Pathway:168249] Innate Immune System - v84:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904799] Update Tracker - [EntityWithAccessionedSequence:9693774] Vimar [mitochondrial outer membrane] - v84:[add_removeReferenceEntity]
[UpdateTracker:9904990] Update Tracker - [Polymer:8876893] Btn-p-S222-ACACB:2Mn2+ polymer [mitochondrial outer membrane] - v84:[modifyName, updateContainedRepeatedUnit]
[UpdateTracker:9905088] Update Tracker - [Complex:5686428] Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904676] Update Tracker - [EntityWithAccessionedSequence:9652026] MAP2K1 L42_K57del [cytosol] - v84:[modifyName]
[UpdateTracker:9905098] Update Tracker - [Complex:198906] MHC Class I interacting with CD160 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904801] Update Tracker - [EntityWithAccessionedSequence:6782604] Ub-179-UBB(153-228) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905040] Update Tracker - [DefinedSet:9010175] p-Y701-STAT1,p-Y705-STAT3,p-Y694-STAT5A,p-STAT5B [cytosol] - v84:[modifyName, updateContainedMemberOrCandidate]
[UpdateTracker:9905011] Update Tracker - [EntityWithAccessionedSequence:8985904] p-Y407-IL9R [plasma membrane] - v84:[modifyName]
[UpdateTracker:9846634] Update Tracker - [Pathway:416476] G alpha (q) signalling events - v84:[updateIndirectRLE]
[UpdateTracker:9904634] Update Tracker - [EntityWithAccessionedSequence:9619993] p-T359,S363,S380.T573,S732-RPS6KA1 [cytosol] - v84:[modifyName]
[UpdateTracker:9846723] Update Tracker - [Reaction:75851] Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA - v84:[modifyText]
[UpdateTracker:9904534] Update Tracker - [Complex:5250919] Nucleosome (H3K9ac) [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904456] Update Tracker - [Complex:9629214] AP-Telomeric DNA:Shelterin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904893] Update Tracker - [DefinedSet:2130388] HLA II beta chain [trans-Golgi network membrane] - v84:[removeHasMember]
[UpdateTracker:9904779] Update Tracker - [SimpleEntity:77087] AdoMet [nucleoplasm] - v84:[add_removeReferenceEntity]
[UpdateTracker:9904899] Update Tracker - [EntityWithAccessionedSequence:2768989] NEXT1 P2514Rfs*4 [plasma membrane] - v84:[add_removeHasModifiedResidue]
[UpdateTracker:9904542] Update Tracker - [Complex:5683809] p-5S-BRCA1:p-2T-BARD1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905092] Update Tracker - [EntityWithAccessionedSequence:5683800] p-S988,S1387,S1423,S1457,S1524-BRCA1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9904543] Update Tracker - [Complex:8871353] p-Y389,400-RUFY1:p-Y389,400-RUFY1:RAB4A:GTP:RAB5:GTP:RAB14:GTP [early endosome membrane] - v84:[modifyName]
[UpdateTracker:9846653] Update Tracker - [Reaction:3928628] VAV exchanges GTP for GDP on RAC1, activating it - v84:[modifyText]
[UpdateTracker:9904870] Update Tracker - [CandidateSet:9652114] MAP2K1 and MAP2K2 mutants [cytosol] - v84:[updateContainedMemberOrCandidate]
[UpdateTracker:9905042] Update Tracker - [Complex:388793] pCTLA-4:Src kinases:SHP2 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904855] Update Tracker - [Complex:5617474] RARA,G:RXRA at HOXB1 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904658] Update Tracker - [Complex:9629442] Tg-Telomeric DNA:Shelterin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904489] Update Tracker - [Complex:5686619] ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904601] Update Tracker - [Complex:5334142] DNMT1:UHRF1:Chromatin with symmetric methylC [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846816] Update Tracker - [Pathway:177929] Signaling by EGFR - v84:[modifyText, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9904765] Update Tracker - [EntityWithAccessionedSequence:77100] p-S5(CTD)-POLR2A [nucleoplasm] - v84:[addHasModifiedResidue, modifyName]
[UpdateTracker:9904757] Update Tracker - [Complex:1236931] Ag peptide bound class I MHC [phagocytic vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904649] Update Tracker - [Complex:203494] Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846800] Update Tracker - [Pathway:165159] MTOR signalling - v84:[updateIndirectRLE]
[UpdateTracker:9905007] Update Tracker - [EntityWithAccessionedSequence:5689157] Ub-413-UBC(381-456) [cytosol] - v84:[modifyName]
[UpdateTracker:9904866] Update Tracker - [Complex:5334113] DNMT1:UHRF1:Chromatin with hemimethylC [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904751] Update Tracker - [Complex:9013982] activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] - v84:[add_removeHasComponent, modifyName]
[UpdateTracker:9904696] Update Tracker - [Complex:8937024] RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904805] Update Tracker - [Complex:2213184] MHC II alpha/beta dimer [trans-Golgi network membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904695] Update Tracker - [EntityWithAccessionedSequence:444292] p-S221,T359,S363,S380,T573,S732-RPS6KA1 [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9905001] Update Tracker - [Complex:391115] p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] - v84:[modifyName]
[UpdateTracker:9846610] Update Tracker - [Reaction:70420] HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P - v84:[addLiteratureReference, modifyText]
[UpdateTracker:9905045] Update Tracker - [Complex:388796] p-Y201,Y218-CTLA4 dimer:B7-1/B7-2 [plasma membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9846688] Update Tracker - [Pathway:9668250] Defective factor IX causes hemophilia B - v84:[updateIndirectRLE]
[UpdateTracker:9904960] Update Tracker - [EntityWithAccessionedSequence:6782590] Ub-109-UBC(77-152) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846663] Update Tracker - [Pathway:8876725] Protein methylation - v84:[updateContainedRLE]
[UpdateTracker:9904731] Update Tracker - [Complex:5617490] HOXA2 bivalent chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904794] Update Tracker - [Complex:5334137] Chromatin with 5mC [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904621] Update Tracker - [Complex:983120] monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904544] Update Tracker - [Complex:8935737] H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905031] Update Tracker - [Complex:5686487] Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9905061] Update Tracker - [Complex:1236934] Antigen peptide bound class I MHC [early endosome membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904508] Update Tracker - [Complex:2213212] alpha beta dimer:Ii trimer:calnexin [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846606] Update Tracker - [Pathway:936964] Activation of IRF3, IRF7 mediated by TBK1, IKBKE - v84:[modifyText, updateContainedRLE]
[UpdateTracker:9904906] Update Tracker - [Complex:2213186] MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904851] Update Tracker - [Complex:5334124] DNMT3B:DNMT3L:Chromatin [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846625] Update Tracker - [Pathway:2142845] Hyaluronan metabolism - v84:[updateIndirectRLE]
[UpdateTracker:9904490] Update Tracker - [Complex:8936581] Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846626] Update Tracker - [Pathway:111885] Opioid Signalling - v84:[updateIndirectRLE]
[UpdateTracker:9904710] Update Tracker - [Complex:5683606] p-4S,2T-BRCA1-A Complex [nucleoplasm] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904459] Update Tracker - [Complex:2213187] MHC class II alpha/beta dimer [endocytic vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846694] Update Tracker - [Reaction:3928644] EPHB binds ITSN1 - v84:[modifyText]
[UpdateTracker:9905029] Update Tracker - [Complex:180277] EGF-like ligands:Phospho-EGFR (- Y992) [plasma membrane] - v84:[addName]
[UpdateTracker:9904702] Update Tracker - [Complex:983412] Antigen peptide bound class I MHC [ER to Golgi transport vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846737] Update Tracker - [Pathway:1660499] Synthesis of PIPs at the plasma membrane - v84:[updateContainedRLE]
[UpdateTracker:9904817] Update Tracker - [Complex:182935] EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904746] Update Tracker - [Complex:5625864] p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846704] Update Tracker - [Reaction:9793836] Tbx6 binds the Mesp2 gene - v84:[modifyText]
[UpdateTracker:9904470] Update Tracker - [Complex:2214394] Nonameric complex [Golgi membrane] - v84:[updateContainedComponent]
[UpdateTracker:9905009] Update Tracker - [Complex:8951489] EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9846707] Update Tracker - [Reaction:177934] EGFR autophosphorylation - v84:[modifyText]
[UpdateTracker:9904584] Update Tracker - [Complex:947509] PXLP-K198-NFS1-2 dimer [cytosol] - v84:[modifyName]
[UpdateTracker:9846631] Update Tracker - [Pathway:70263] Gluconeogenesis - v84:[updateContainedRLE]
[UpdateTracker:9904900] Update Tracker - [EntityWithAccessionedSequence:5689138] Ub-179-UBB(153-228) [cytosol] - v84:[modifyName]
[UpdateTracker:9846811] Update Tracker - [Reaction:177925] SHC1 binds to the phosphorylated EGF receptor:ligand complex - v84:[modifyText]
[UpdateTracker:9904651] Update Tracker - [Complex:8935719] RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904461] Update Tracker - [Complex:8878073] p-S249,S273,S276-RUNX1:CBFB:p-S,T-EP300 [nucleoplasm] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9904438] Update Tracker - [Complex:5686616] ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904449] Update Tracker - [Complex:9670115] Telomere:Shelterin:Nucleosome (H3F3A) [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904516] Update Tracker - [Complex:2245190] Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846638] Update Tracker - [Pathway:9793380] Formation of paraxial mesoderm - v84:[updateContainedRLE]
[UpdateTracker:9905037] Update Tracker - [Complex:198911] HLA-C Cw4 (group 2) [plasma membrane] - v84:[add_removeHasComponent]
[UpdateTracker:9904953] Update Tracker - [Complex:8964279] G alpha (s):GTP:p-Y419-SRC [plasma membrane] - v84:[modifyName]
[UpdateTracker:9846657] Update Tracker - [Reaction:156673] Regulation of KIF23 (MKLP1) by phosphorylation - v84:[modifyText]
[UpdateTracker:9904568] Update Tracker - [Complex:8985982] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y649-STAT5 [plasma membrane] - v84:[modifyName, updateContainedComponent]
[UpdateTracker:9846647] Update Tracker - [Reaction:8866941] MID1IP1 binds THRSP - v84:[modifyText]
[UpdateTracker:9904959] Update Tracker - [EntityWithAccessionedSequence:873798] p-Y457-IFNGR1 [plasma membrane] - v84:[modifyName]
[UpdateTracker:9846711] Update Tracker - [Pathway:434048] TLR3 cascade - v84:[updateContainedPathway]
[UpdateTracker:9846819] Update Tracker - [Pathway:72203] Processing of Capped Intron-Containing Pre-mRNA - v84:[updateContainedPathway]
[UpdateTracker:9904705] Update Tracker - [Complex:428490] Pak:Dock:Robo:Slit [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904891] Update Tracker - [Complex:202157] Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904466] Update Tracker - [Complex:180326] EGF-like ligands:p-5Y-EGFR:GRB2:p-5Y-GAB1:SHP2 [plasma membrane] - v84:[addName, updateContainedComponent]
[UpdateTracker:9904815] Update Tracker - [Complex:2130379] Nonameric complex [ER to Golgi transport vesicle membrane] - v84:[updateContainedComponent]
[UpdateTracker:9904850] Update Tracker - [EntityWithAccessionedSequence:6782646] Ub-565-UBC(533-608) [nucleoplasm] - v84:[modifyName]
[UpdateTracker:9846759] Update Tracker - [Reaction:75240] TRADD:TRAF2:RIP1:FADD complex binds Pro-Caspase 8 - v84:[addRegulator, modifyText]
[UpdateTracker:9846676] Update Tracker - [Pathway:597592] Post-translational protein modification - v84:[updateIndirectRLE]
[UpdateTracker:9846734] Update Tracker - [Reaction:177284] PKA phosphorylates PDE4B - v84:[add_removeInput, add_removeOutput]
[UpdateTracker:9904771] Update Tracker - [Complex:5684107] DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-BRCA1-C complex [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9846624] Update Tracker - [Pathway:2980766] Nuclear Envelope Breakdown - v84:[updateContainedPathway]
[UpdateTracker:9904581] Update Tracker - [EntityWithAccessionedSequence:9628866] UNC93B1 P345Pfs*103 [endoplasmic reticulum membrane] - v84:[modifyEndCoordinate, modifyName]
[UpdateTracker:9904500] Update Tracker - [DefinedSet:2130380] HLA II beta chain [ER to Golgi transport vesicle membrane] - v84:[removeHasMember]
[UpdateTracker:9904620] Update Tracker - [EntityWithAccessionedSequence:9629915] NEIL1 Q282* [cytosol] - v84:[addHasModifiedResidue, addName]
[UpdateTracker:9904697] Update Tracker - [EntityWithAccessionedSequence:2976671] p-S69-BCL2L11 [cytosol] - v84:[modifyName]
[UpdateTracker:9904497] Update Tracker - [Complex:5693547] p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] - v84:[updateContainedComponent]
[UpdateTracker:9904478] Update Tracker - [EntityWithAccessionedSequence:6782602] Ub-105-UBC(77-152) [nucleoplasm] - v84:[modifyName]

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