Reactome | POU3F1 (OCT6) binds the OTX2 gene and activates expression (...

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created	[InstanceEdit:9833271] May, Bruce, 2023-04-18
dbId	9833261
displayName	POU3F1 (OCT6) binds the OTX2 gene and activates expression (...
literatureReference	[LiteratureReference:9832825] The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways [LiteratureReference:9833077] Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors
schemaClass	Summation
text	POU3F1 (OCT6) binds the OTX2 gene and activates expression (inferred from mouse embryonic stem cells in Zhu et al. 2014 and anterior neural progenitors differentiated from mouse embryonal carcinoma cells in Inoue et al. 2012).

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