Reactome | 35 on 2010-12-31

Schema > Release > Entries

35 on 2010-12-31 Show undefined attributes

dbId	9790014
displayName	35 on 2010-12-31
modified	[InstanceEdit:9982963] Weiser, Joel, 2026-02-20
releaseDate	2010-12-31
releaseNumber	35
schemaClass	Release

Referrals

(release)

[UpdateTracker:9790143] Update Tracker - [Pathway:196071] Metabolism of steroid hormones - v35:[addHasEvent, updateContainedPathway]
[UpdateTracker:9790019] Update Tracker - [Pathway:196849] Metabolism of water-soluble vitamins and cofactors - v35:[add_removeHasEvent, updateContainedPathway]
[UpdateTracker:9790105] Update Tracker - [Reaction:173740] Factor B binds to C3(H2O) - v35:[modifyText]
[UpdateTracker:9790184] Update Tracker - [Pathway:429914] Deadenylation-dependent mRNA decay - v35:[updateIndirectRLE]
[UpdateTracker:9869837] Update Tracker - [DefinedSet:166763] C4 activators [plasma membrane] - v35:[updateContainedMemberOrCandidate]
[UpdateTracker:9790134] Update Tracker - [Pathway:500792] GPCR ligand binding - v35:[updateContainedPathway]
[UpdateTracker:9790084] Update Tracker - [BlackBoxEvent:450187] TAK1 is activated within the TAK1 complex - v35:[modifyText]
[UpdateTracker:9869866] Update Tracker - [Complex:182629] IgG [extracellular region] - v35:[updateContainedComponent]
[UpdateTracker:9869863] Update Tracker - [Complex:187565] Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] - v35:[updateContainedComponent]
[UpdateTracker:9790151] Update Tracker - [Reaction:189423] PPO oxidises PPGEN9 to PRIN9 - v35:[add_removeOutput]
[UpdateTracker:9869873] Update Tracker - [Complex:170661] G alpha-olf:GTP [plasma membrane] - v35:[modifyName]
[UpdateTracker:9790081] Update Tracker - [Pathway:211000] Gene Silencing by RNA - v35:[removeHasEvent]
[UpdateTracker:9869887] Update Tracker - [Complex:879365] AGER ligands:AGER [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9790071] Update Tracker - [Reaction:450337] Activated TAK1 phosphorylates MKK4/MKK7 - v35:[modifyText]
[UpdateTracker:9869912] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v35:[addHasMember]
[UpdateTracker:9790041] Update Tracker - [Pathway:445989] TAK1-dependent IKK and NF-kappa-B activation - v35:[modifyText, updateContainedRLE]
[UpdateTracker:9869841] Update Tracker - [EntityWithAccessionedSequence:166780] C2a [extracellular region] - v35:[modifyName]
[UpdateTracker:9790127] Update Tracker - [Reaction:173636] Formation of classic pathway C5 convertase - v35:[addSummation, add_removeInput]
[UpdateTracker:9790150] Update Tracker - [Pathway:446728] Cell junction organization - v35:[updateIndirectRLE]
[UpdateTracker:9869923] Update Tracker - [Complex:173582] Antigen:IgG:C1Q:2xC1R:2xC1S [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9869842] Update Tracker - [Complex:173749] Cell surface:C3b:Bb [plasma membrane] - v35:[addHasComponent, modifyName, updateContainedComponent]
[UpdateTracker:9869825] Update Tracker - [Complex:847073] K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] - v35:[add_removeHasComponent, modifyName]
[UpdateTracker:9869922] Update Tracker - [EntityWithAccessionedSequence:156709] KIF23 [nucleoplasm] - v35:[modifyName]
[UpdateTracker:9790066] Update Tracker - [Pathway:196854] Metabolism of vitamins and cofactors - v35:[updateContainedPathway]
[UpdateTracker:9790142] Update Tracker - [Pathway:389661] Glyoxylate metabolism and glycine degradation - v35:[addHasEvent]
[UpdateTracker:9790098] Update Tracker - [Reaction:166753] Conversion of C4 into C4a and C4b - v35:[add_removeInput, add_removeOutput, modifyText]
[UpdateTracker:9869894] Update Tracker - [EntityWithAccessionedSequence:166736] S-(L-isoglutamyl)-L-cysteine-C4A(757-1446) [extracellular region] - v35:[modifyName]
[UpdateTracker:9790187] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v35:[removeHasEvent]
[UpdateTracker:9790102] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v35:[modifyText]
[UpdateTracker:9790129] Update Tracker - [Pathway:193648] NRAGE signals death through JNK - v35:[updateContainedRLE]
[UpdateTracker:9869901] Update Tracker - [Complex:189443] ALAS2 homodimer (pyridoxal phosphate cofactor) [mitochondrial matrix] - v35:[add_removeHasComponent]
[UpdateTracker:9790141] Update Tracker - [Reaction:879930] STAT5 is recruited by JAK2 - v35:[modifyText]
[UpdateTracker:9869818] Update Tracker - [EntityWithAccessionedSequence:62725] NRAS [plasma membrane] - v35:[modifyEndCoordinate]
[UpdateTracker:9869891] Update Tracker - [DefinedSet:209933] TPH [cytosol] - v35:[add_removeHasMember, modifyName]
[UpdateTracker:9790027] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v35:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9790092] Update Tracker - [Pathway:76005] Response to elevated platelet cytosolic Ca2+ - v35:[updateIndirectRLE]
[UpdateTracker:9790048] Update Tracker - [Reaction:451561] NEMO binds polyubiquitinated IRAK1 - v35:[modifyText]
[UpdateTracker:9869860] Update Tracker - [Complex:177691] viral dsRNA:TLR3:TRIF:pUb-TRAF6:TAB1:TAB2,TAB3:free polyUb: p-TAK1 [endosome membrane] - v35:[add_removeHasComponent, modifyName]
[UpdateTracker:9790108] Update Tracker - [Reaction:74213] APRT catalyzes the conversion of adenine to AMP - v35:[modifyText]
[UpdateTracker:9869865] Update Tracker - [Complex:446066] CD151:BP230:BP180:Plectin:Integrin alpha 6 beta 4: Laminin [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9790140] Update Tracker - [Pathway:382551] Transport of small molecules - v35:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9790155] Update Tracker - [Reaction:450257] Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 - v35:[modifyText]
[UpdateTracker:9790094] Update Tracker - [Pathway:166663] Initial triggering of complement - v35:[addHasEvent, updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9869911] Update Tracker - [EntityWithAccessionedSequence:195122] RACGAP1 [cytosol] - v35:[addName]
[UpdateTracker:9869918] Update Tracker - [Complex:173635] C4b:C2a:C3b [plasma membrane] - v35:[addCompartment, add_removeHasComponent, modifyName, updateContainedComponent]
[UpdateTracker:9790156] Update Tracker - [Pathway:111885] Opioid Signalling - v35:[updateContainedPathway]
[UpdateTracker:9869900] Update Tracker - [Complex:187547] CUL1:SKP1:SKP2:CKS1B [nucleoplasm] - v35:[updateContainedComponent]
[UpdateTracker:9790125] Update Tracker - [Reaction:77591] Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex - v35:[removeInput]
[UpdateTracker:9790022] Update Tracker - [Pathway:512988] Interleukin-3, Interleukin-5 and GM-CSF signaling - v35:[modifyText, removeHasEvent, updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9869883] Update Tracker - [EntityWithAccessionedSequence:450264] TAB3 [cytosol] - v35:[add_removeReferenceEntity]
[UpdateTracker:9790172] Update Tracker - [Pathway:209931] Serotonin and melatonin biosynthesis - v35:[updateContainedRLE]
[UpdateTracker:9869850] Update Tracker - [EntityWithAccessionedSequence:140585] FGG [extracellular region] - v35:[modifyName]
[UpdateTracker:9869885] Update Tracker - [EntityWithAccessionedSequence:265181] KIF5B [cytosol] - v35:[modifyName]
[UpdateTracker:9869859] Update Tracker - [DefinedSet:772536] Activated TAK complexes [cytosol] - v35:[updateContainedMemberOrCandidate]
[UpdateTracker:9790074] Update Tracker - [Pathway:450302] activated TAK1 mediates p38 MAPK activation - v35:[modifyText, updateContainedRLE]
[UpdateTracker:9869917] Update Tracker - [Complex:68819] 26S proteasome [cytosol] - v35:[addHasComponent]
[UpdateTracker:9790173] Update Tracker - [Pathway:71064] Lysine catabolism - v35:[updateContainedRLE]
[UpdateTracker:9869886] Update Tracker - [Complex:173752] Cell surface:C3b:Bb:Properdin [plasma membrane] - v35:[addHasComponent, modifyName, updateContainedComponent]
[UpdateTracker:9869826] Update Tracker - [Complex:170656] (Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] - v35:[add_removeHasComponent, modifyName]
[UpdateTracker:9790031] Update Tracker - [Pathway:426048] Arachidonate production from DAG - v35:[updateContainedRLE]
[UpdateTracker:9790178] Update Tracker - [Pathway:168138] Toll Like Receptor 9 (TLR9) Cascade - v35:[addHasEvent]
[UpdateTracker:9869920] Update Tracker - [Complex:189446] ALAS1 homodimer (pyridoxal phosphate cofactor) [mitochondrial matrix] - v35:[add_removeHasComponent]
[UpdateTracker:9790160] Update Tracker - [Pathway:597592] Post-translational protein modification - v35:[updateContainedPathway]
[UpdateTracker:9790040] Update Tracker - [Reaction:70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - v35:[addInput]
[UpdateTracker:9869869] Update Tracker - [Complex:182451] C3(H2O):Bb [extracellular region] - v35:[addName, updateContainedComponent]
[UpdateTracker:9790065] Update Tracker - [Pathway:168181] Toll Like Receptor 7/8 (TLR7/8) Cascade - v35:[addHasEvent]
[UpdateTracker:9869899] Update Tracker - [Complex:170683] (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] - v35:[add_removeHasComponent, modifyName, updateContainedComponent]
[UpdateTracker:9790136] Update Tracker - [Reaction:382613] PEX-19 docks ABCD1/D2/D3 to peroximal membrane - v35:[removeCatalystActivity]
[UpdateTracker:9790128] Update Tracker - [Reaction:110144] ADP + ADP <=> AMP + ATP [AK2] - v35:[modifyText]
[UpdateTracker:9790107] Update Tracker - [Pathway:168256] Immune System - v35:[addHasEvent, updateContainedPathway]
[UpdateTracker:9869856] Update Tracker - [EntityWithAccessionedSequence:449189] Abl1 [cytosol] - v35:[modifyName]
[UpdateTracker:9790110] Update Tracker - [Pathway:112040] G-protein mediated events - v35:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9790109] Update Tracker - [Reaction:166015] Association of LBP with LPS - v35:[modifyText]
[UpdateTracker:9790058] Update Tracker - [Pathway:193144] Estrogen biosynthesis - v35:[addHasEvent]
[UpdateTracker:9869827] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9790182] Update Tracker - [Reaction:216757] 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane - v35:[addInput]
[UpdateTracker:9869864] Update Tracker - [Complex:749455] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9790033] Update Tracker - [Reaction:166792] Conversion of C2 into C2a and C2b - v35:[modifyText]
[UpdateTracker:9869878] Update Tracker - [Complex:181410] TLR6:TLR2:ligand:CD14:CD36 [plasma membrane] - v35:[addCompartment]
[UpdateTracker:9790046] Update Tracker - [Reaction:847070] Phosphorylated TAK1 dissociates from the TLR3 receptor complex - v35:[modifyText]
[UpdateTracker:9790194] Update Tracker - [Pathway:912526] Interleukin receptor SHC signaling - v35:[modifyText, updateContainedRLE]
[UpdateTracker:9869913] Update Tracker - [Complex:173619] Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9790043] Update Tracker - [Pathway:901042] Calnexin/calreticulin cycle - v35:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9790112] Update Tracker - [Pathway:168164] Toll Like Receptor 3 (TLR3) Cascade - v35:[updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9790168] Update Tracker - [Reaction:442724] Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) - v35:[removeOutput]
[UpdateTracker:9790180] Update Tracker - [Reaction:452102] p-STAT5 dimerizes - v35:[modifyText]
[UpdateTracker:9869867] Update Tracker - [Complex:187541] CUL1:SKP1:SKP2 [nucleoplasm] - v35:[add_removeHasComponent]
[UpdateTracker:9790073] Update Tracker - [Pathway:438064] Post NMDA receptor activation events - v35:[updateIndirectRLE]
[UpdateTracker:9790089] Update Tracker - [Pathway:173623] Classical antibody-mediated complement activation - v35:[updateContainedRLE]
[UpdateTracker:9869902] Update Tracker - [DefinedSet:879487] AGE adducts [extracellular region] - v35:[removeSpecies]
[UpdateTracker:9790154] Update Tracker - [Pathway:71291] Metabolism of amino acids and derivatives - v35:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9869871] Update Tracker - [Complex:166034] LPS:GPI-anchored CD14 [plasma membrane] - v35:[add_removeHasComponent]
[UpdateTracker:9869875] Update Tracker - [Complex:198877] Antigen-bound antibody bound to lymphoid Fc gamma receptors [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9869830] Update Tracker - [DefinedSet:173750] C3 convertases [plasma membrane] - v35:[addHasMember, modifyName, updateContainedMemberOrCandidate]
[UpdateTracker:9869892] Update Tracker - [Complex:445022] AP2 clathrin:L1:KIF4:microtubule [cytosol] - v35:[updateContainedComponent]
[UpdateTracker:9869921] Update Tracker - [Complex:446010] BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] - v35:[addHasComponent, updateContainedComponent]
[UpdateTracker:9790068] Update Tracker - [Pathway:15869] Metabolism of nucleotides - v35:[updateIndirectRLE]
[UpdateTracker:9790055] Update Tracker - [Pathway:181438] Toll Like Receptor 2 (TLR2) Cascade - v35:[updateContainedPathway]
[UpdateTracker:9790165] Update Tracker - [Pathway:450321] JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 - v35:[modifyText, updateContainedRLE]
[UpdateTracker:9790018] Update Tracker - [Pathway:194068] Bile acid and bile salt metabolism - v35:[updateIndirectRLE]
[UpdateTracker:9790026] Update Tracker - [Reaction:450333] Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 - v35:[modifyText]
[UpdateTracker:9790044] Update Tracker - [Pathway:192456] Digestion of dietary lipid - v35:[addHasEvent]
[UpdateTracker:9790119] Update Tracker - [Pathway:166786] Creation of C4 and C2 activators - v35:[updateIndirectRLE]
[UpdateTracker:9790039] Update Tracker - [Reaction:375384] Bombesin-like receptors bind bombesin homologues - v35:[modifyText]
[UpdateTracker:9790103] Update Tracker - [Reaction:71676] GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O - v35:[modifyText]
[UpdateTracker:9790021] Update Tracker - [BlackBoxEvent:879942] The receptor is activated - v35:[modifyText]
[UpdateTracker:9869811] Update Tracker - [DefinedSet:428003] Histidine/di-peptides [cytosol] - v35:[updateContainedMemberOrCandidate]
[UpdateTracker:9869879] Update Tracker - [Complex:174554] C3b:Bb:C3b:Properdin [plasma membrane] - v35:[modifyName, removeCompartment, updateContainedComponent]
[UpdateTracker:9790086] Update Tracker - [Pathway:109582] Hemostasis - v35:[addHasEvent]
[UpdateTracker:9869835] Update Tracker - [DefinedSet:791492] Ligands of GPCRs that activate Gq/11 [extracellular region] - v35:[addHasMember]
[UpdateTracker:9790115] Update Tracker - [Reaction:173626] Activation of C1r - v35:[addRegulator]
[UpdateTracker:9869855] Update Tracker - [EntityWithAccessionedSequence:186631] IAPP(1-89) [cytosol] - v35:[addName]
[UpdateTracker:9790179] Update Tracker - [Pathway:382556] ABC-family proteins mediated transport - v35:[modifyText, updateContainedRLE]
[UpdateTracker:9790015] Update Tracker - [Pathway:446203] Asparagine N-linked glycosylation - v35:[addHasEvent, updateContainedPathway]
[UpdateTracker:9869851] Update Tracker - [Complex:181226] TLR1:TLR2:TLR1/2 ligand:CD14 [plasma membrane] - v35:[addCompartment]
[UpdateTracker:9790131] Update Tracker - [Pathway:450294] MAP kinase activation - v35:[modifyText, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9790052] Update Tracker - [Reaction:170671] G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex - v35:[add_removeInput]
[UpdateTracker:9790183] Update Tracker - [Pathway:611105] Respiratory electron transport - v35:[updateContainedRLE]
[UpdateTracker:9869852] Update Tracker - [Complex:173618] Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9869848] Update Tracker - [Complex:198904] Antigen peptide bound class I MHC [plasma membrane] - v35:[modifyName]
[UpdateTracker:9790063] Update Tracker - [Reaction:442739] PDPK1 phosphorylates RSKs - v35:[removeOutput]
[UpdateTracker:9790148] Update Tracker - [Reaction:450031] Interleukin-3 receptor alpha: Interleukin-3 binds IL3RB:JAK2 - v35:[modifyText]
[UpdateTracker:9790020] Update Tracker - [Pathway:173736] Alternative complement activation - v35:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9790161] Update Tracker - [Pathway:556833] Metabolism of lipids - v35:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9869820] Update Tracker - [Complex:188132] C-ter TLR7 dimer:TLR7, TLR8 ligands [endosome membrane] - v35:[add_removeCompartment]
[UpdateTracker:9790042] Update Tracker - [Reaction:74376] (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) - v35:[addLiteratureReference, modifyText]
[UpdateTracker:9790061] Update Tracker - [Reaction:913374] Phosphorylated SHC1 recruits SHIP - v35:[modifyText]
[UpdateTracker:9790082] Update Tracker - [Pathway:375276] Peptide ligand-binding receptors - v35:[addHasEvent, updateContainedRLE]
[UpdateTracker:9790186] Update Tracker - [Pathway:72203] Processing of Capped Intron-Containing Pre-mRNA - v35:[modifyText]
[UpdateTracker:9869895] Update Tracker - [Complex:114618] Fibrinogen [extracellular region] - v35:[modifyName]
[UpdateTracker:9790145] Update Tracker - [Pathway:71240] Tryptophan catabolism - v35:[addHasEvent]
[UpdateTracker:9790137] Update Tracker - [Reaction:266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - v35:[addInput]
[UpdateTracker:9869832] Update Tracker - [Complex:389671] AGXT dimer [peroxisomal matrix] - v35:[addLiteratureReference, add_removeHasComponent]
[UpdateTracker:9790079] Update Tracker - [Pathway:75067] Processing of Capped Intronless Pre-mRNA - v35:[modifyText, updateIndirectRLE]
[UpdateTracker:9869877] Update Tracker - [DefinedSet:428026] Di-peptides/tri-peptides [cytosol] - v35:[updateContainedMemberOrCandidate]
[UpdateTracker:9790023] Update Tracker - [Pathway:168188] Toll Like Receptor TLR6:TLR2 Cascade - v35:[addHasEvent]
[UpdateTracker:9869836] Update Tracker - [Complex:450277] TAB1:TAB2,TAB3:TAK1 [cytosol] - v35:[add_removeHasComponent, modifyName]
[UpdateTracker:9790106] Update Tracker - [Pathway:191273] Cholesterol biosynthesis - v35:[updateContainedRLE]
[UpdateTracker:9790139] Update Tracker - [Reaction:183130] C3(H2O):Factor Bb cleaves C3 to C3b and C3a - v35:[add_removeOutput, modifyText]
[UpdateTracker:9790166] Update Tracker - [Reaction:163214] Electron transfer from reduced cytochrome c to molecular oxygen - v35:[modifyText]
[UpdateTracker:9869824] Update Tracker - [Complex:264969] Translocon:TRAP [endoplasmic reticulum membrane] - v35:[addHasComponent]
[UpdateTracker:9790132] Update Tracker - [Reaction:168910] RIP1 facilitates IKK complex phosphorylation - v35:[addRegulator, addSummation, add_removeCatalystActivity, modifyText]
[UpdateTracker:9790149] Update Tracker - [Reaction:110145] AMP + ATP <=> ADP + ADP [AK2] - v35:[modifyText]
[UpdateTracker:9790130] Update Tracker - [Pathway:373080] Class B/2 (Secretin family receptors) - v35:[addHasEvent]
[UpdateTracker:9790159] Update Tracker - [Pathway:444257] RSK activation - v35:[updateContainedRLE]
[UpdateTracker:9869840] Update Tracker - [EntityWithAccessionedSequence:381083] EDEM1 [endoplasmic reticulum quality control compartment] - v35:[add_removeCompartment]
[UpdateTracker:9869905] Update Tracker - [Complex:177689] viral dsRNA:TLR3:TRIF:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [endosome membrane] - v35:[add_removeHasComponent, modifyName]
[UpdateTracker:9790157] Update Tracker - [Reaction:111285] Formation of phosphoribosyl pyrophosphate amidotransferase tetramer - v35:[modifyText]
[UpdateTracker:9790060] Update Tracker - [Pathway:168898] Toll-like Receptor Cascades - v35:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9790171] Update Tracker - [Pathway:532668] N-glycan trimming in the ER and Calnexin/Calreticulin cycle - v35:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9790177] Update Tracker - [Reaction:193362] ABCB11 transports bile salts from cytosol to extracellular region - v35:[addInput]
[UpdateTracker:9790126] Update Tracker - [Pathway:162906] HIV Infection - v35:[removeHasEvent]
[UpdateTracker:9790120] Update Tracker - [Polymerisation:450358] Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation - v35:[modifyText]
[UpdateTracker:9790088] Update Tracker - [Reaction:426043] 2-AG hydrolysis to arachidonate by MAGL - v35:[addInput, addOutput]
[UpdateTracker:9869903] Update Tracker - [EntityWithAccessionedSequence:422070] GH1 [extracellular region] - v35:[addName, addSummation]
[UpdateTracker:9790030] Update Tracker - [Pathway:196819] Vitamin B1 (thiamin) metabolism - v35:[addHasEvent]
[UpdateTracker:9790133] Update Tracker - [Pathway:114508] Effects of PIP2 hydrolysis - v35:[updateIndirectRLE]
[UpdateTracker:9869915] Update Tracker - [Complex:446086] Type II hemidesmosome [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9869829] Update Tracker - [Complex:442735] Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] - v35:[modifyName]
[UpdateTracker:9790083] Update Tracker - [BlackBoxEvent:186583] Hnf6-dependent synthesis of Ngn3 protein during morphogenesis - v35:[addLiteratureReference, addRegulator, modifyText]
[UpdateTracker:9790191] Update Tracker - [Reaction:170674] Dissociation of the Gi alpha:G olf complex - v35:[add_removeOutput]
[UpdateTracker:9869816] Update Tracker - [DefinedSet:380110] Ligand:GPCR complexes that activate Gq/11 [plasma membrane] - v35:[addHasMember]
[UpdateTracker:9869844] Update Tracker - [DefinedSet:791493] GPCRs that activate Gq/11 [plasma membrane] - v35:[addHasMember]
[UpdateTracker:9869858] Update Tracker - [EntityWithAccessionedSequence:166729] C4 alpha [extracellular region] - v35:[modifyName]
[UpdateTracker:9790080] Update Tracker - [Pathway:446652] Interleukin-1 family signaling - v35:[updateContainedRLE]
[UpdateTracker:9790122] Update Tracker - [Pathway:112315] Transmission across Chemical Synapses - v35:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9790045] Update Tracker - [Reaction:173745] Factor D cleaves C3(H2O)-bound Factor B - v35:[modifyText, removeInput, removeOutput]
[UpdateTracker:9869839] Update Tracker - [Complex:182450] C3(H2O) [extracellular region] - v35:[addName]
[UpdateTracker:9790049] Update Tracker - [Reaction:177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - v35:[modifyText]
[UpdateTracker:9790147] Update Tracker - [Pathway:168249] Innate Immune System - v35:[addHasEvent, updateContainedPathway]
[UpdateTracker:9790193] Update Tracker - [Reaction:73618] 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate - v35:[modifyText]
[UpdateTracker:9790118] Update Tracker - [Pathway:73621] Pyrimidine catabolism - v35:[addHasEvent, modifyText, updateContainedRLE]
[UpdateTracker:9869868] Update Tracker - [Complex:199174] Antigen-bound Ig G Antibody [extracellular region] - v35:[updateContainedComponent]
[UpdateTracker:9790077] Update Tracker - [Pathway:193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol - v35:[updateContainedRLE]
[UpdateTracker:9869897] Update Tracker - [Complex:445013] KIF4 dimer [cytosol] - v35:[modifyName]
[UpdateTracker:9790038] Update Tracker - [Pathway:446107] Type I hemidesmosome assembly - v35:[updateContainedRLE]
[UpdateTracker:9790093] Update Tracker - [Reaction:168184] Activated TAK1 mediates phosphorylation of the IKK Complex - v35:[modifyText]
[UpdateTracker:9869831] Update Tracker - [DefinedSet:879455] AGER ligands [extracellular region] - v35:[updateContainedMemberOrCandidate]
[UpdateTracker:9790050] Update Tracker - [Pathway:159418] Recycling of bile acids and salts - v35:[updateContainedRLE]
[UpdateTracker:9790024] Update Tracker - [Reaction:430028] Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion - v35:[addLiteratureReference]
[UpdateTracker:9790167] Update Tracker - [Pathway:199991] Membrane Trafficking - v35:[updateContainedPathway]
[UpdateTracker:9869880] Update Tracker - [Complex:166850] TLR4:LY96:LPS:CD14 [plasma membrane] - v35:[add_removeHasComponent]
[UpdateTracker:9790076] Update Tracker - [Reaction:168929] Viral dsRNA:TLR3 recruits TRIF (TICAM1) - v35:[modifyText]
[UpdateTracker:9790070] Update Tracker - [Pathway:112316] Neuronal System - v35:[updateContainedPathway]
[UpdateTracker:9869914] Update Tracker - [Complex:173737] Cell surface:C3b:CFB [plasma membrane] - v35:[add_removeHasComponent, modifyName]
[UpdateTracker:9790047] Update Tracker - [Reaction:183122] Factor D cleaves C3b-bound Factor B - v35:[modifyText]
[UpdateTracker:9790059] Update Tracker - [Pathway:209776] Metabolism of amine-derived hormones - v35:[updateIndirectRLE]
[UpdateTracker:9790121] Update Tracker - [Pathway:204998] Cell death signalling via NRAGE, NRIF and NADE - v35:[updateIndirectRLE]
[UpdateTracker:9790100] Update Tracker - [Pathway:189445] Metabolism of porphyrins - v35:[updateIndirectRLE]
[UpdateTracker:9790175] Update Tracker - [Pathway:189451] Heme biosynthesis - v35:[updateContainedRLE]
[UpdateTracker:9790016] Update Tracker - [Pathway:166020] Transfer of LPS from LBP carrier to CD14 - v35:[modifyText]
[UpdateTracker:9869854] Update Tracker - [Complex:170655] G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9869845] Update Tracker - [EntityWithAccessionedSequence:195067] ARHGEF9 [cytosol] - v35:[addName]
[UpdateTracker:9790116] Update Tracker - [Reaction:912291] Incorrectly folded glycoproteins translocate to the ERQC - v35:[modifyText]
[UpdateTracker:9790181] Update Tracker - [Reaction:174551] Formation of alternative pathway C5 convertase - v35:[modifyText]
[UpdateTracker:9790123] Update Tracker - [Reaction:166795] Formation of Classical C3 convertase (C4b:C2a complex) - v35:[add_removeInput]
[UpdateTracker:9869815] Update Tracker - [Complex:182529] C3(H2O):CFB [extracellular region] - v35:[addName, updateContainedComponent]
[UpdateTracker:9790034] Update Tracker - [Pathway:114608] Platelet degranulation - v35:[updateContainedRLE]
[UpdateTracker:9790153] Update Tracker - [Pathway:77595] Processing of Intronless Pre-mRNAs - v35:[updateContainedRLE]
[UpdateTracker:9790117] Update Tracker - [Reaction:173739] Spontaneous hydrolysis of C3 thioester - v35:[modifyText]
[UpdateTracker:9869828] Update Tracker - [Complex:187568] Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] - v35:[updateContainedComponent]
[UpdateTracker:9869817] Update Tracker - [EntityWithAccessionedSequence:140841] FGA(20-866) [extracellular region] - v35:[modifyName]
[UpdateTracker:9790162] Update Tracker - [Reaction:216723] 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane - v35:[addInput]
[UpdateTracker:9869904] Update Tracker - [Complex:166732] Complement factor 4A [extracellular region] - v35:[modifyName]
[UpdateTracker:9790029] Update Tracker - [Reaction:265783] ABCG5:ABCG8 transports sterols from cytosol to extracellular region - v35:[addInput]
[UpdateTracker:9869919] Update Tracker - [EntityWithAccessionedSequence:174100] UBE2E1 [cytosol] - v35:[addName]
[UpdateTracker:9790174] Update Tracker - [Reaction:191303] FDPS dimer transfers IPPP to GPP - v35:[addLiteratureReference, add_removeCatalystActivity, modifyText]
[UpdateTracker:9869849] Update Tracker - [Complex:170659] (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] - v35:[add_removeHasComponent, modifyName]
[UpdateTracker:9790017] Update Tracker - [Pathway:174577] Activation of C3 and C5 - v35:[updateContainedRLE]
[UpdateTracker:9790056] Update Tracker - [Pathway:392499] Metabolism of proteins - v35:[updateContainedPathway]
[UpdateTracker:9790152] Update Tracker - [Pathway:199977] ER to Golgi Anterograde Transport - v35:[updateContainedPathway]
[UpdateTracker:9790025] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v35:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9869857] Update Tracker - [EntityWithAccessionedSequence:188000] ZFYVE20 [endosome membrane] - v35:[modifyName]
[UpdateTracker:9869853] Update Tracker - [Complex:198897] TCR interacting with antigen-bearing MHC Class I [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9790078] Update Tracker - [Reaction:73589] 5,6-dihydrouracil + H2O => beta-ureidopropionate - v35:[modifyText]
[UpdateTracker:9790111] Update Tracker - [Reaction:168930] Viral dsRNA:TLR3:TRIF complex recruits RIP1 - v35:[modifyText]
[UpdateTracker:9790158] Update Tracker - [Pathway:166658] Complement cascade - v35:[addSummation, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9869823] Update Tracker - [Polymer:182548] Properdin oligomer [extracellular region] - v35:[modifyName]
[UpdateTracker:9869893] Update Tracker - [Complex:188192] PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] - v35:[add_removeHasComponent]
[UpdateTracker:9790189] Update Tracker - [Reaction:73591] beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 - v35:[modifyText]
[UpdateTracker:9790095] Update Tracker - [Reaction:166817] Cleavage of C3 by C3 convertases - v35:[addSummation]
[UpdateTracker:9790144] Update Tracker - [Pathway:168927] TICAM1, RIP1-mediated IKK complex recruitment - v35:[updateContainedRLE]
[UpdateTracker:9869910] Update Tracker - [DefinedSet:197037] Ig Kappa Light Chain V Region [extracellular region] - v35:[add_removeHasMember, modifyName]
[UpdateTracker:9869861] Update Tracker - [Complex:445997] Integrin alpha 6:beta 4:Plectin:BP180:Laminin-322 complex [plasma membrane] - v35:[add_removeHasComponent]
[UpdateTracker:9869843] Update Tracker - [Complex:879479] AGE adducts:Peptide [extracellular region] - v35:[updateContainedComponent]
[UpdateTracker:9790037] Update Tracker - [Reaction:74372] uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] - v35:[addLiteratureReference, modifyText]
[UpdateTracker:9869908] Update Tracker - [DefinedSet:197042] Ig Heavy Chain V Region [extracellular region] - v35:[addHasMember, modifyName]
[UpdateTracker:9790035] Update Tracker - [Pathway:74217] Purine salvage - v35:[updateContainedRLE]
[UpdateTracker:9869847] Update Tracker - [DefinedSet:428037] Di-peptides/tri-peptides [extracellular region] - v35:[updateContainedMemberOrCandidate]
[UpdateTracker:9790087] Update Tracker - [Pathway:192105] Synthesis of bile acids and bile salts - v35:[updateIndirectRLE]
[UpdateTracker:9790169] Update Tracker - [Reaction:382575] ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix - v35:[add_removeInput, add_removeOutput]
[UpdateTracker:9790067] Update Tracker - [Reaction:183126] Factor B binds to surface-associated C3b - v35:[add_removeInput]
[UpdateTracker:9790072] Update Tracker - [Pathway:112308] Presynaptic depolarization and calcium channel opening - v35:[updateContainedRLE]
[UpdateTracker:9869846] Update Tracker - [DefinedSet:173759] C5 convertases [plasma membrane] - v35:[modifyName, updateContainedMemberOrCandidate]
[UpdateTracker:9790176] Update Tracker - [Reaction:191322] FDPS dimer transfers IPPP to DMAPP - v35:[addLiteratureReference, add_removeCatalystActivity, modifyText]
[UpdateTracker:9790190] Update Tracker - [Reaction:210420] Ca2+ influx through voltage gated Ca2+ channels - v35:[addRegulator, modifyText]
[UpdateTracker:9869889] Update Tracker - [EntityWithAccessionedSequence:450247] TAB3 [endosome membrane] - v35:[add_removeReferenceEntity]
[UpdateTracker:9790075] Update Tracker - [Reaction:71825] G6PC hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (liver) - v35:[addLiteratureReference, modifyText]
[UpdateTracker:9790054] Update Tracker - [Pathway:74259] Purine catabolism - v35:[updateContainedRLE]
[UpdateTracker:9869822] Update Tracker - [Complex:182956] CBL:Beta-Pix:CDC42:GTP [cytosol] - v35:[add_removeHasComponent]
[UpdateTracker:9869819] Update Tracker - [EntityWithAccessionedSequence:166737] C4A-derived C4a [extracellular region] - v35:[modifyName]
[UpdateTracker:9790114] Update Tracker - [Pathway:372790] Signaling by GPCR - v35:[updateContainedPathway]
[UpdateTracker:9790124] Update Tracker - [Reaction:209828] Tryptophan is hydroxylated - v35:[addLiteratureReference, modifyText]
[UpdateTracker:9869874] Update Tracker - [Complex:749447] Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9869876] Update Tracker - [DefinedSet:189429] ALAS1,2 [mitochondrial matrix] - v35:[updateContainedMemberOrCandidate]
[UpdateTracker:9790096] Update Tracker - [Reaction:450346] activated human TAK1 phosphorylates MKK3/MKK6 - v35:[modifyText]
[UpdateTracker:9869907] Update Tracker - [EntityWithAccessionedSequence:166731] C4A(1454-1744) [extracellular region] - v35:[modifyName]
[UpdateTracker:9790053] Update Tracker - [Reaction:481044] Surface deployment of platelet alpha granule membrane components - v35:[add_removeInput, add_removeOutput]
[UpdateTracker:9790138] Update Tracker - [Pathway:168179] Toll Like Receptor TLR1:TLR2 Cascade - v35:[addHasEvent]
[UpdateTracker:9790013] Update Tracker - [Reaction:173754] Properdin stabilizes C3b:Bb bound to cell surfaces - v35:[modifyText]
[UpdateTracker:9790064] Update Tracker - [Reaction:432956] BP230 is recruited to the hemidesmosome - v35:[addInput]
[UpdateTracker:9790051] Update Tracker - [Pathway:170670] Adenylate cyclase inhibitory pathway - v35:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9790091] Update Tracker - [Pathway:449147] Signaling by Interleukins - v35:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9869821] Update Tracker - [DefinedSet:197028] Ig Lamda Light Chain V Region [extracellular region] - v35:[addHasMember, modifyName]
[UpdateTracker:9790085] Update Tracker - [Reaction:442749] CaMKK autophosphorylates in the nucleus - v35:[removeOutput]
[UpdateTracker:9790097] Update Tracker - [Pathway:166016] Toll Like Receptor 4 (TLR4) Cascade - v35:[updateContainedPathway, updateContainedRLE]
[UpdateTracker:9869862] Update Tracker - [EntityWithAccessionedSequence:166734] C4A(20-675) [extracellular region] - v35:[modifyName]
[UpdateTracker:9869909] Update Tracker - [DefinedSet:427984] Histidine/di-peptides [lysosomal lumen] - v35:[updateContainedMemberOrCandidate]
[UpdateTracker:9790113] Update Tracker - [BlackBoxEvent:912527] SHC1 mediates cytokine-induced phosphorylation of GAB2 - v35:[modifyText, removeCatalystActivity]
[UpdateTracker:9790104] Update Tracker - [Reaction:205136] GTP-bound RAC contributes to JNK activation - v35:[addRegulator, removeCatalystActivity]
[UpdateTracker:9869916] Update Tracker - [Complex:173552] Antigen:IgG [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9790032] Update Tracker - [Reaction:451418] Pellino ubiquitinates IRAK1 - v35:[modifyText]
[UpdateTracker:9869896] Update Tracker - [Complex:749451] Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] - v35:[updateContainedComponent]
[UpdateTracker:9790135] Update Tracker - [Pathway:499943] Interconversion of nucleotide di- and triphosphates - v35:[updateContainedRLE]
[UpdateTracker:9869870] Update Tracker - [Complex:166784] Cell surface:C4b:C2a [plasma membrane] - v35:[addCompartment, add_removeHasComponent, modifyName]
[UpdateTracker:9869881] Update Tracker - [EntityWithAccessionedSequence:389669] PXLP-AGXT [peroxisomal matrix] - v35:[addLiteratureReference]
[UpdateTracker:9790185] Update Tracker - [Reaction:111289] Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer - v35:[modifyText]
[UpdateTracker:9790101] Update Tracker - [Reaction:168166] NF-kappa-B complex is transported from cytosol to nucleus - v35:[modifyText]
[UpdateTracker:9790146] Update Tracker - [Pathway:112314] Neurotransmitter receptors and postsynaptic signal transmission - v35:[addHasEvent]
[UpdateTracker:9790090] Update Tracker - [Pathway:73614] Pyrimidine salvage - v35:[updateContainedRLE]
[UpdateTracker:9869814] Update Tracker - [DefinedSet:197021] Ig Antibody Light Chain [extracellular region] - v35:[add_removeHasMember]
[UpdateTracker:9869884] Update Tracker - [EntityWithAccessionedSequence:174244] UBE2C [cytosol] - v35:[addName]
[UpdateTracker:9869872] Update Tracker - [DefinedSet:481033] Platelet alpha granule contents [extracellular region] - v35:[updateContainedMemberOrCandidate]
[UpdateTracker:9790170] Update Tracker - [Pathway:429958] mRNA decay by 3' to 5' exoribonuclease - v35:[updateContainedRLE]
[UpdateTracker:9790036] Update Tracker - [Reaction:450348] Activated human JNKs migrate to nucleoplasm - v35:[modifyText]
[UpdateTracker:9790062] Update Tracker - [Pathway:73817] Purine ribonucleoside monophosphate biosynthesis - v35:[updateContainedRLE]
[UpdateTracker:9869834] Update Tracker - [EntityWithAccessionedSequence:156721] KIF20A [nucleoplasm] - v35:[modifyName]
[UpdateTracker:9869838] Update Tracker - [EntityWithAccessionedSequence:166781] C2b [extracellular region] - v35:[modifyName]
[UpdateTracker:9790099] Update Tracker - [BlackBoxEvent:915148] Correctly folded glycoproteins translocate to the Golgi - v35:[addLiteratureReference, modifyText]
[UpdateTracker:9869890] Update Tracker - [EntityWithAccessionedSequence:140846] FGB(31-491) [extracellular region] - v35:[modifyName]
[UpdateTracker:9790192] Update Tracker - [Reaction:450222] Active p38 MAPK phosphorylates MAPKAPK2 or 3 - v35:[modifyText]
[UpdateTracker:9790069] Update Tracker - [Reaction:446870] Polyubiquitinated TRAF6 binds the TAK1 complex - v35:[modifyText]

Cite Us!