Reactome | 58 on 2016-10-05

Schema > Release > Entries

58 on 2016-10-05 Show undefined attributes

dbId	9782699
displayName	58 on 2016-10-05
modified	[InstanceEdit:9982963] Weiser, Joel, 2026-02-20
releaseDate	2016-10-05
releaseNumber	58
schemaClass	Release

Referrals

(release)

[UpdateTracker:9894936] Update Tracker - [Complex:1181140] p-ACVR1B:ACVR2:EGF-CFC [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782792] Update Tracker - [Reaction:5686475] SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) - v58:[add_removeInput, modifyText]
[UpdateTracker:9782719] Update Tracker - [Pathway:5668541] TNFR2 non-canonical NF-kB pathway - v58:[updateContainedPathway]
[UpdateTracker:9782760] Update Tracker - [Reaction:6793685] Ubiquitinated TP53 translocates to the cytosol - v58:[modifyText]
[UpdateTracker:9894915] Update Tracker - [Complex:427410] NoRC:pRNA:HDAC:DNMT [nucleoplasm] - v58:[updateContainedComponent]
[UpdateTracker:9895011] Update Tracker - [Complex:169142] NS1 Homodimer:PKR Complex [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9782831] Update Tracker - [Reaction:163213] Transfer of electrons through the succinate dehydrogenase complex - v58:[addLiteratureReference, addRegulator, modifyText]
[UpdateTracker:9782819] Update Tracker - [Reaction:378978] CGA and CGB3 bind to form Human chorionic gonadotropin (hCG) - v58:[addLiteratureReference, add_removeInput, modifyText]
[UpdateTracker:9894893] Update Tracker - [Complex:8869200] EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] - v58:[updateContainedComponent]
[UpdateTracker:9895025] Update Tracker - [EntityWithAccessionedSequence:1614383] FGFR1c P252S [plasma membrane] - v58:[removeInferredFrom]
[UpdateTracker:9894968] Update Tracker - [EntityWithAccessionedSequence:5362778] IHH [extracellular region] - v58:[addEndCoordinate, modifyStartCoordinate, removeName]
[UpdateTracker:9782841] Update Tracker - [Pathway:1660662] Glycosphingolipid metabolism - v58:[addHasEvent]
[UpdateTracker:9782946] Update Tracker - [Pathway:5654712] FRS-mediated FGFR4 signaling - v58:[removeHasEvent]
[UpdateTracker:9782974] Update Tracker - [Pathway:1660661] Sphingolipid de novo biosynthesis - v58:[updateContainedRLE]
[UpdateTracker:9782850] Update Tracker - [Pathway:5674135] MAP2K and MAPK activation - v58:[updateContainedRLE]
[UpdateTracker:9782825] Update Tracker - [Reaction:114548] G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) - v58:[addLiteratureReference, modifyText]
[UpdateTracker:9894925] Update Tracker - [DefinedSet:377600] RAP1 [plasma membrane] - v58:[modifyName]
[UpdateTracker:9782725] Update Tracker - [Reaction:2993780] Transfer of SUMO1 from E1 to UBE2I (UBC9) - v58:[addRegulator]
[UpdateTracker:9782959] Update Tracker - [Reaction:430076] GP1b-IX-V binds 14-3-3-zeta - v58:[add_removeInput]
[UpdateTracker:9894784] Update Tracker - [Complex:5389843] 55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9895020] Update Tracker - [Complex:191891] Spliceosomal m3G capped snRNAs with SMN:SM protein complex bound [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9782903] Update Tracker - [Pathway:8864260] Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors - v58:[addLiteratureReference, modifyText, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9894876] Update Tracker - [Complex:5419262] 55S ribosome:mRNA:tRNA [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894833] Update Tracker - [Complex:8868051] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894924] Update Tracker - [EntityWithAccessionedSequence:1614386] FGFR1c P252T [plasma membrane] - v58:[removeInferredFrom]
[UpdateTracker:9782829] Update Tracker - [Reaction:2201341] Endocytosis of TRAM (TICAM2) - v58:[addLiteratureReference, addRegulator, modifyText]
[UpdateTracker:9894786] Update Tracker - [Complex:983126] Ag-substrate:E3:E2:Ub [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9782814] Update Tracker - [Pathway:975957] Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) - v58:[updateContainedRLE]
[UpdateTracker:9894896] Update Tracker - [SimpleEntity:163579] CHEST [lipid droplet] - v58:[addName]
[UpdateTracker:9782907] Update Tracker - [Reaction:5672980] Dissociation of RAS:RAF complex - v58:[modifyText]
[UpdateTracker:9782889] Update Tracker - [Pathway:381183] ATF6 (ATF6-alpha) activates chaperone genes - v58:[addLiteratureReference]
[UpdateTracker:9782701] Update Tracker - [Pathway:112382] Formation of RNA Pol II elongation complex - v58:[updateContainedRLE]
[UpdateTracker:9782745] Update Tracker - [Pathway:2219528] PI3K/AKT Signaling in Cancer - v58:[updateIndirectRLE]
[UpdateTracker:9895006] Update Tracker - [Complex:113722] Aborted elongation complex after arrest [nucleoplasm] - v58:[addHasComponent]
[UpdateTracker:9782746] Update Tracker - [Pathway:611105] Respiratory electron transport - v58:[updateContainedRLE]
[UpdateTracker:9782888] Update Tracker - [Pathway:2142688] Synthesis of 5-eicosatetraenoic acids - v58:[addHasEvent]
[UpdateTracker:9782981] Update Tracker - [Pathway:5654741] Signaling by FGFR3 - v58:[updateContainedPathway]
[UpdateTracker:9782775] Update Tracker - [Reaction:177925] SHC1 binds to the phosphorylated EGF receptor:ligand complex - v58:[addLiteratureReference, modifyText]
[UpdateTracker:9895000] Update Tracker - [Complex:8868629] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894822] Update Tracker - [Complex:432098] Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894971] Update Tracker - [EntityWithAccessionedSequence:8864427] CGB3 Gene [nucleoplasm] - v58:[modifyName]
[UpdateTracker:9894889] Update Tracker - [CandidateSet:196094] STARD3:STARD3NL, STARD4,6 [cytosol] - v58:[addName, add_removeHasMember]
[UpdateTracker:9782705] Update Tracker - [Pathway:381340] Transcriptional regulation of white adipocyte differentiation - v58:[updateContainedRLE]
[UpdateTracker:9894810] Update Tracker - [Complex:8867034] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782958] Update Tracker - [Pathway:210745] Regulation of gene expression in beta cells - v58:[updateContainedRLE]
[UpdateTracker:9782943] Update Tracker - [Pathway:4839726] Chromatin organization - v58:[updateContainedPathway]
[UpdateTracker:9782945] Update Tracker - [Pathway:1482883] Acyl chain remodeling of DAG and TAG - v58:[updateContainedRLE]
[UpdateTracker:9894901] Update Tracker - [Complex:6785734] MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm] - v58:[updateContainedComponent]
[UpdateTracker:9782816] Update Tracker - [Pathway:5654706] FRS-mediated FGFR3 signaling - v58:[removeHasEvent]
[UpdateTracker:9894845] Update Tracker - [Complex:377620] Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894943] Update Tracker - [EntityWithAccessionedSequence:420814] ATF6(420-670) [Golgi membrane] - v58:[addHasModifiedResidue]
[UpdateTracker:9782978] Update Tracker - [Pathway:77289] Mitochondrial Fatty Acid Beta-Oxidation - v58:[addHasEvent, updateContainedPathway]
[UpdateTracker:9782995] Update Tracker - [Pathway:109582] Hemostasis - v58:[updateContainedPathway]
[UpdateTracker:9782932] Update Tracker - [Pathway:5654738] Signaling by FGFR2 - v58:[updateContainedPathway]
[UpdateTracker:9894934] Update Tracker - [Complex:914209] p(Y700,731,774)-CBL:CRK:RAPGEF1 [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9894969] Update Tracker - [Complex:5419280] 55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782804] Update Tracker - [Pathway:177929] Signaling by EGFR - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9782983] Update Tracker - [Pathway:109581] Apoptosis - v58:[updateContainedPathway]
[UpdateTracker:9894789] Update Tracker - [Complex:5419282] 55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894899] Update Tracker - [Complex:4331338] E2F1:TFDP1:PMAIP1 Gene [nucleoplasm] - v58:[updateContainedComponent]
[UpdateTracker:9894913] Update Tracker - [Complex:182961] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] - v58:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9894926] Update Tracker - [Complex:5368277] 55S ribosome [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782942] Update Tracker - [Pathway:1250342] PI3K events in ERBB4 signaling - v58:[updateContainedPathway]
[UpdateTracker:9782990] Update Tracker - [Pathway:381033] ATF6 (ATF6-alpha) activates chaperones - v58:[addLiteratureReference, updateContainedPathway, updateContainedRLE]
[UpdateTracker:9894849] Update Tracker - [Complex:8867035] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782867] Update Tracker - [Pathway:3214841] PKMTs methylate histone lysines - v58:[addHasEvent, updateContainedRLE]
[UpdateTracker:9895014] Update Tracker - [Complex:3240769] SUZ12 Gene:E2F1/2/3:DP1/2 [nucleoplasm] - v58:[updateContainedComponent]
[UpdateTracker:9894811] Update Tracker - [Complex:163622] G alpha (s):GTP:Adenylate cyclase [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782698] Update Tracker - [Reaction:5638157] WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) - v58:[addLiteratureReference, add_removeCatalystActivity, modifyText]
[UpdateTracker:9894846] Update Tracker - [Complex:83676] C to U edited ApoB RNA:Editosome complex [nucleoplasm] - v58:[add_removeHasComponent]
[UpdateTracker:9895019] Update Tracker - [Complex:8867753] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782910] Update Tracker - [Pathway:5673001] RAF/MAP kinase cascade - v58:[updateIndirectRLE]
[UpdateTracker:9894818] Update Tracker - [EntityWithAccessionedSequence:182512] CDKN1A [cytosol] - v58:[addName]
[UpdateTracker:9782973] Update Tracker - [Pathway:166016] Toll Like Receptor 4 (TLR4) Cascade - v58:[updateContainedRLE]
[UpdateTracker:9895028] Update Tracker - [DefinedSet:8869164] ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] - v58:[addHasMember]
[UpdateTracker:9782954] Update Tracker - [BlackBoxEvent:1234159] Proteasome proteolyzes ub-HIF-alpha - v58:[addCatalystActivity, add_removeInput, add_removeOutput]
[UpdateTracker:9782886] Update Tracker - [Reaction:200555] acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate - v58:[modifyText]
[UpdateTracker:9782897] Update Tracker - [Pathway:196108] Pregnenolone biosynthesis - v58:[updateContainedRLE]
[UpdateTracker:9894804] Update Tracker - [Complex:5672723] activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894950] Update Tracker - [Complex:191881] SMN complex [cytosol] - v58:[addHasComponent, addLiteratureReference]
[UpdateTracker:9894851] Update Tracker - [Complex:1234101] hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] - v58:[updateContainedComponent]
[UpdateTracker:9782979] Update Tracker - [Pathway:2559583] Cellular Senescence - v58:[updateContainedPathway]
[UpdateTracker:9782730] Update Tracker - [Pathway:1362409] Mitochondrial iron-sulfur cluster biogenesis - v58:[addLiteratureReference, updateContainedRLE]
[UpdateTracker:9782996] Update Tracker - [Pathway:1592230] Mitochondrial biogenesis - v58:[updateIndirectRLE]
[UpdateTracker:9782875] Update Tracker - [Pathway:73857] RNA Polymerase II Transcription - v58:[updateIndirectRLE]
[UpdateTracker:9782823] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v58:[updateContainedRLE]
[UpdateTracker:9782986] Update Tracker - [Pathway:2424491] DAP12 signaling - v58:[updateContainedPathway]
[UpdateTracker:9782766] Update Tracker - [Reaction:5615637] POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) - v58:[add_removeInput, add_removeOutput, modifyText]
[UpdateTracker:9782930] Update Tracker - [Pathway:74182] Ketone body metabolism - v58:[updateContainedPathway]
[UpdateTracker:9782817] Update Tracker - [Pathway:432722] Golgi Associated Vesicle Biogenesis - v58:[addHasEvent]
[UpdateTracker:9782839] Update Tracker - [Pathway:194068] Bile acid and bile salt metabolism - v58:[updateContainedPathway]
[UpdateTracker:9894827] Update Tracker - [Complex:354126] RAP1:GTP [plasma membrane] - v58:[add_removeHasComponent, modifyName, updateContainedComponent]
[UpdateTracker:9894815] Update Tracker - [Complex:158130] factor XIa:GPIb:GPIX:GPV complex [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894885] Update Tracker - [Complex:68644] RB1:E2F1,E2F2,E2F3:TFDP1,TFDP2: [nucleoplasm] - v58:[add_removeHasComponent, modifyName]
[UpdateTracker:9895026] Update Tracker - [Complex:8849118] NXF1,2:NXT1 [nucleoplasm] - v58:[addLiteratureReference, add_removeHasComponent, modifyName]
[UpdateTracker:9782703] Update Tracker - [Reaction:428205] ceramide + H2O => stearate + sphingosine [Golgi] - v58:[add_removeOutput]
[UpdateTracker:9782747] Update Tracker - [Pathway:3700989] Transcriptional Regulation by TP53 - v58:[updateContainedPathway]
[UpdateTracker:9894963] Update Tracker - [Complex:443900] Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894990] Update Tracker - [DefinedSet:2316432] Activator:PI3K [plasma membrane] - v58:[addHasMember]
[UpdateTracker:9894909] Update Tracker - [Complex:392865] Prostacyclin:prostacyclin receptor:G-protein Gs (active) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894816] Update Tracker - [CandidateSet:2400011] PI3K mutants,Activator:PI3K [plasma membrane] - v58:[updateContainedMemberOrCandidate]
[UpdateTracker:9894994] Update Tracker - [Complex:1169392] ISGylated NS1 [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9782716] Update Tracker - [Pathway:5654708] Downstream signaling of activated FGFR3 - v58:[updateContainedPathway]
[UpdateTracker:9894874] Update Tracker - [SimpleEntity:76633] QH2 [mitochondrial inner membrane] - v58:[addName]
[UpdateTracker:9894986] Update Tracker - [EntityWithAccessionedSequence:3786256] CDKN1A gene [nucleoplasm] - v58:[modifyName]
[UpdateTracker:9894984] Update Tracker - [Complex:5419275] 55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782921] Update Tracker - [Reaction:198613] AKT phosphorylates p21Cip1 and p27Kip1 - v58:[add_removeInput]
[UpdateTracker:9782915] Update Tracker - [Pathway:2454202] Fc epsilon receptor (FCERI) signaling - v58:[updateContainedPathway]
[UpdateTracker:9894877] Update Tracker - [Complex:113648] Aborted replication complex [nucleoplasm] - v58:[updateContainedComponent]
[UpdateTracker:9894914] Update Tracker - [DefinedSet:418572] G-protein alpha (12/13):GTP [plasma membrane] - v58:[updateContainedMemberOrCandidate]
[UpdateTracker:9782728] Update Tracker - [Reaction:2399969] AKT1 E17K mutant phosphorylates p21Cip1 and p27Kip1 - v58:[add_removeInput]
[UpdateTracker:9782761] Update Tracker - [Reaction:75851] Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA - v58:[addLiteratureReference, addRegulator, modifyText]
[UpdateTracker:9894953] Update Tracker - [Complex:191791] SMN:SM protein complex [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9894865] Update Tracker - [Complex:422310] GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894828] Update Tracker - [EntityWithAccessionedSequence:4088168] CDC25A gene [nucleoplasm] - v58:[modifyName]
[UpdateTracker:9894894] Update Tracker - [EntityWithAccessionedSequence:1637902] FGFR2 K660M [plasma membrane] - v58:[removeInferredFrom]
[UpdateTracker:9895007] Update Tracker - [Complex:1234100] ub-hydroxyPro-HIF-alpha [nucleoplasm] - v58:[modifyName]
[UpdateTracker:9894803] Update Tracker - [Complex:352501] SIN3 HDAC corepressor complex [nucleoplasm] - v58:[updateContainedComponent]
[UpdateTracker:9894982] Update Tracker - [Complex:8849140] NXF1,2:NXT1 [cytosol] - v58:[addLiteratureReference, add_removeHasComponent, modifyName]
[UpdateTracker:9782741] Update Tracker - [Pathway:1483255] PI Metabolism - v58:[addHasEvent, updateContainedPathway]
[UpdateTracker:9894972] Update Tracker - [CandidateSet:8849364] Kinesins [cytosol] - v58:[addHasCandidate]
[UpdateTracker:9782769] Update Tracker - [Pathway:166166] MyD88-independent TLR4 cascade - v58:[updateContainedRLE]
[UpdateTracker:9782787] Update Tracker - [Pathway:8866904] Negative regulation of activity of TFAP2 (AP-2) family transcription factors - v58:[addLiteratureReference, modifyText, updateContainedRLE]
[UpdateTracker:9782822] Update Tracker - [Pathway:1430728] Metabolism - v58:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9782951] Update Tracker - [BlackBoxEvent:6791218] 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA - v58:[addCatalystActivity, addLiteratureReference, modifyText]
[UpdateTracker:9782784] Update Tracker - [Pathway:6794362] Protein-protein interactions at synapses - v58:[addHasEvent]
[UpdateTracker:9782872] Update Tracker - [Pathway:196854] Metabolism of vitamins and cofactors - v58:[updateContainedPathway]
[UpdateTracker:9895001] Update Tracker - [DefinedSet:1252222] Substrates of MIA40-ERV1 [mitochondrial intermembrane space] - v58:[addHasMember, addLiteratureReference]
[UpdateTracker:9782743] Update Tracker - [Pathway:1482801] Acyl chain remodelling of PS - v58:[addHasEvent]
[UpdateTracker:9782707] Update Tracker - [Reaction:200406] CPT1A,B transfers PALM to CAR - v58:[modifyText]
[UpdateTracker:9894794] Update Tracker - [EntityWithAccessionedSequence:195131] SRGAP2 [cytosol] - v58:[addName]
[UpdateTracker:9782786] Update Tracker - [Reaction:1234183] Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha - v58:[addLiteratureReference, add_removeInput]
[UpdateTracker:9782780] Update Tracker - [Pathway:5362517] Signaling by Retinoic Acid - v58:[updateContainedRLE]
[UpdateTracker:9783003] Update Tracker - [Reaction:430096] GP1b-IX-V binds filamin - v58:[add_removeInput]
[UpdateTracker:9894941] Update Tracker - [Complex:744885] Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782702] Update Tracker - [Pathway:186797] Signaling by PDGF - v58:[addHasEvent, updateContainedPathway]
[UpdateTracker:9894800] Update Tracker - [DefinedSet:68640] E2F1/2/3 [nucleoplasm] - v58:[modifyName]
[UpdateTracker:9894997] Update Tracker - [Complex:8871149] PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894814] Update Tracker - [Complex:428907] TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894873] Update Tracker - [Complex:354130] Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782950] Update Tracker - [Pathway:977347] Serine biosynthesis - v58:[addHasEvent]
[UpdateTracker:9894843] Update Tracker - [Complex:3222079] DAXX:(PolyUb,p-S166,S188-MDM2):USP7 [nucleoplasm] - v58:[modifyName]
[UpdateTracker:9894979] Update Tracker - [Complex:113426] Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] - v58:[addHasComponent, addLiteratureReference]
[UpdateTracker:9782912] Update Tracker - [Reaction:1181155] The NODAL Receptor binds NODAL ligands - v58:[add_removeRegulator]
[UpdateTracker:9782835] Update Tracker - [Pathway:72306] tRNA processing - v58:[updateContainedPathway]
[UpdateTracker:9894880] Update Tracker - [SimpleEntity:73663] CoQ [mitochondrial inner membrane] - v58:[add_removeReferenceEntity, removeName]
[UpdateTracker:9894999] Update Tracker - [Complex:422322] G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9783001] Update Tracker - [Pathway:5173105] O-linked glycosylation - v58:[addHasEvent, updateContainedRLE]
[UpdateTracker:9782820] Update Tracker - [Reaction:183072] EGFR non-clathrin mediated endocytosis - v58:[add_removeInput]
[UpdateTracker:9895002] Update Tracker - [DefinedSet:391181] Ligand:GPCR complexes that activate Gs [plasma membrane] - v58:[add_removeHasMember]
[UpdateTracker:9894847] Update Tracker - [Complex:8871150] PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782898] Update Tracker - [Reaction:5672966] RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers - v58:[modifyText]
[UpdateTracker:9782962] Update Tracker - [Pathway:186763] Downstream signal transduction - v58:[updateContainedPathway]
[UpdateTracker:9894945] Update Tracker - [Complex:4331325] E2F1:TFDP1:BBC3 Gene [nucleoplasm] - v58:[updateContainedComponent]
[UpdateTracker:9894961] Update Tracker - [Complex:429532] GP1b-IX-V complex:activated thrombin (factor IIa) [plasma membrane] - v58:[add_removeHasComponent]
[UpdateTracker:9782987] Update Tracker - [Reaction:429698] PRKD1,2,3 phosphorylates CERT1-2 - v58:[add_removeCatalystActivity, modifyText]
[UpdateTracker:9894891] Update Tracker - [Complex:1234141] VHL:EloB,C:CUL2:RBX1 [nucleoplasm] - v58:[addLiteratureReference]
[UpdateTracker:9894998] Update Tracker - [GenomeEncodedEntity:5250898] unknown ubiquitin ligase [cytosol] - v58:[modifyName]
[UpdateTracker:9782802] Update Tracker - [Pathway:8866910] TFAP2 (AP-2) family regulates transcription of growth factors and their receptors - v58:[addHasEvent, addLiteratureReference, modifyText, updateContainedRLE]
[UpdateTracker:9894912] Update Tracker - [Complex:159100] NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] - v58:[modifyName, updateContainedComponent]
[UpdateTracker:9782832] Update Tracker - [Pathway:5663202] Diseases of signal transduction by growth factor receptors and second messengers - v58:[addHasEvent]
[UpdateTracker:9894802] Update Tracker - [DefinedSet:398080] G-protein G12/G13 (active) [plasma membrane] - v58:[updateContainedMemberOrCandidate]
[UpdateTracker:9894837] Update Tracker - [Complex:5368273] 55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894974] Update Tracker - [Complex:159259] NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9894862] Update Tracker - [Complex:354137] Focal complex [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782992] Update Tracker - [Pathway:71387] Metabolism of carbohydrates - v58:[updateContainedPathway]
[UpdateTracker:9782813] Update Tracker - [Reaction:200474] NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD - v58:[add_removeInput, add_removeOutput]
[UpdateTracker:9894790] Update Tracker - [Complex:1181341] CERBERUS:NODAL [extracellular region] - v58:[addLiteratureReference, add_removeHasComponent]
[UpdateTracker:9782955] Update Tracker - [Reaction:112381] Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex - v58:[addInput, addLiteratureReference]
[UpdateTracker:9894959] Update Tracker - [Complex:158162] factor XI:GPIb-IX-V complex [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782881] Update Tracker - [Pathway:2172127] DAP12 interactions - v58:[updateContainedPathway]
[UpdateTracker:9894871] Update Tracker - [Complex:113720] Paused processive elongation complex [nucleoplasm] - v58:[addHasComponent]
[UpdateTracker:9782782] Update Tracker - [Reaction:879575] SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol - v58:[addLiteratureReference, modifyText]
[UpdateTracker:9782965] Update Tracker - [Pathway:162582] Signal Transduction - v58:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9894965] Update Tracker - [Complex:372652] CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782755] Update Tracker - [Pathway:2142789] Ubiquinol biosynthesis - v58:[updateContainedRLE]
[UpdateTracker:9782826] Update Tracker - [Pathway:453279] Mitotic G1 phase and G1/S transition - v58:[updateContainedPathway]
[UpdateTracker:9782793] Update Tracker - [Pathway:375276] Peptide ligand-binding receptors - v58:[updateContainedPathway]
[UpdateTracker:9783004] Update Tracker - [Reaction:2162194] COQ9 dimer:COQ7:Fe2+ hydroxylates DMQ10H2 to DeMQ10H2 - v58:[addLiteratureReference, modifyText]
[UpdateTracker:9782939] Update Tracker - [Pathway:512988] Interleukin-3, Interleukin-5 and GM-CSF signaling - v58:[updateIndirectRLE]
[UpdateTracker:9894948] Update Tracker - [Complex:354080] Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782857] Update Tracker - [Pathway:69563] p53-Dependent G1 DNA Damage Response - v58:[updateIndirectRLE]
[UpdateTracker:9782848] Update Tracker - [Pathway:2426168] Activation of gene expression by SREBF (SREBP) - v58:[updateContainedRLE]
[UpdateTracker:9894783] Update Tracker - [Complex:398056] G-protein alpha (13):GTP [plasma membrane] - v58:[add_removeCompartment, add_removeHasComponent]
[UpdateTracker:9894820] Update Tracker - [Complex:114527] G13-activated p115-RhoGEF [plasma membrane] - v58:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9782837] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v58:[updateContainedRLE]
[UpdateTracker:9894906] Update Tracker - [Complex:113726] Elongation complex with separated and uncleaved transcript [nucleoplasm] - v58:[addHasComponent]
[UpdateTracker:9894947] Update Tracker - [Complex:398145] G-protein alpha (12/13):LARG [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894801] Update Tracker - [EntityWithAccessionedSequence:450046] IL2RA [plasma membrane] - v58:[addName]
[UpdateTracker:9894795] Update Tracker - [Complex:430104] GPIb-IX-V:vWF:filamin-A [plasma membrane] - v58:[add_removeHasComponent]
[UpdateTracker:9782972] Update Tracker - [Pathway:1483206] Glycerophospholipid biosynthesis - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9894922] Update Tracker - [Complex:372688] BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782843] Update Tracker - [Pathway:2142753] Arachidonic acid metabolism - v58:[updateContainedPathway]
[UpdateTracker:9894779] Update Tracker - [CandidateSet:1307799] Products of MIA40:ERV1 [mitochondrial intermembrane space] - v58:[addHasCandidate, addHasMember, addLiteratureReference]
[UpdateTracker:9782779] Update Tracker - [Pathway:5662702] Melanin biosynthesis - v58:[addHasEvent, updateContainedRLE]
[UpdateTracker:9782908] Update Tracker - [Pathway:5654743] Signaling by FGFR4 - v58:[updateContainedPathway]
[UpdateTracker:9894842] Update Tracker - [SimpleEntity:176655] LCA [cytosol] - v58:[addName]
[UpdateTracker:9782797] Update Tracker - [Pathway:392499] Metabolism of proteins - v58:[updateContainedPathway]
[UpdateTracker:9894981] Update Tracker - [Complex:398074] Heterotrimeric G-protein G13 (active) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894830] Update Tracker - [Complex:164358] G alpha (s):GTP [plasma membrane] - v58:[add_removeHasComponent]
[UpdateTracker:9782724] Update Tracker - [Pathway:927802] Nonsense-Mediated Decay (NMD) - v58:[updateIndirectRLE]
[UpdateTracker:9894932] Update Tracker - [DefinedSet:1252217] Products of MIA40-ERV1 [mitochondrial intermembrane space] - v58:[addHasMember, addLiteratureReference]
[UpdateTracker:9782777] Update Tracker - [Pathway:6806003] Regulation of TP53 Expression and Degradation - v58:[updateIndirectRLE]
[UpdateTracker:9782765] Update Tracker - [Pathway:180292] GAB1 signalosome - v58:[updateContainedPathway]
[UpdateTracker:9782896] Update Tracker - [Reaction:5662662] Tyrosinase oxidises tyrosine to dopaquinone - v58:[addLiteratureReference, addRegulator, modifyText]
[UpdateTracker:9782961] Update Tracker - [Pathway:3247509] Chromatin modifying enzymes - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9894976] Update Tracker - [Complex:113815] NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] - v58:[modifyName, updateContainedComponent]
[UpdateTracker:9782999] Update Tracker - [Pathway:5674400] Constitutive Signaling by AKT1 E17K in Cancer - v58:[updateContainedRLE]
[UpdateTracker:9782756] Update Tracker - [Reaction:112379] Recruitment of elongation factors to form elongation complex - v58:[addLiteratureReference, add_removeInput]
[UpdateTracker:9783002] Update Tracker - [Pathway:1660499] Synthesis of PIPs at the plasma membrane - v58:[addHasEvent]
[UpdateTracker:9782862] Update Tracker - [Reaction:561054] OCT2 mediates tubular secretion of organic cations in the kidney - v58:[addLiteratureReference, addRegulator, modifyText]
[UpdateTracker:9894996] Update Tracker - [Complex:432197] AVPR2:AVP:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782847] Update Tracker - [Pathway:1266738] Developmental Biology - v58:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9782740] Update Tracker - [Pathway:77352] Beta oxidation of butanoyl-CoA to acetyl-CoA - v58:[addHasEvent]
[UpdateTracker:9894964] Update Tracker - [Complex:354103] Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894978] Update Tracker - [Complex:429544] GPIb-IX-V:Collagen type I fibril:vWF:14-3-3-zeta [plasma membrane] - v58:[add_removeHasComponent, modifyName]
[UpdateTracker:9782975] Update Tracker - [Pathway:5693537] Resolution of D-Loop Structures - v58:[updateIndirectRLE]
[UpdateTracker:9782861] Update Tracker - [Reaction:77609] Binding of APOBEC-1 to form editosome - v58:[add_removeInput]
[UpdateTracker:9894897] Update Tracker - [Complex:182936] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] - v58:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9895015] Update Tracker - [DefinedSet:5686489] SLX1A:SLX4:MUS81:EME1,(MUS81:EME2),GEN1 [nucleoplasm] - v58:[modifyName, updateContainedMemberOrCandidate]
[UpdateTracker:9894916] Update Tracker - [Complex:377622] Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782991] Update Tracker - [Pathway:1250196] SHC1 events in ERBB2 signaling - v58:[addHasEvent]
[UpdateTracker:9782796] Update Tracker - [Pathway:1257604] PIP3 activates AKT signaling - v58:[addHasEvent, updateIndirectRLE]
[UpdateTracker:9894905] Update Tracker - [EntityWithAccessionedSequence:381075] ATF6(1-380) [cytosol] - v58:[addLiteratureReference, add_removeCompartment, modifyEndCoordinate, modifyName]
[UpdateTracker:9894975] Update Tracker - [Complex:8868632] PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782776] Update Tracker - [Pathway:69242] S Phase - v58:[updateIndirectRLE]
[UpdateTracker:9894792] Update Tracker - [DefinedSet:157462] CCNE [cytosol] - v58:[addName]
[UpdateTracker:9782994] Update Tracker - [Pathway:6782315] tRNA modification in the nucleus and cytosol - v58:[addHasEvent]
[UpdateTracker:9782878] Update Tracker - [Pathway:180336] SHC1 events in EGFR signaling - v58:[updateContainedRLE]
[UpdateTracker:9782845] Update Tracker - [Pathway:69541] Stabilization of p53 - v58:[updateContainedRLE]
[UpdateTracker:9782709] Update Tracker - [Reaction:2404199] IGF1,2:IGF1R autophosphorylates - v58:[addRegulator]
[UpdateTracker:9894952] Update Tracker - [DefinedSet:8867603] CLASP proteins:cargo [plasma membrane] - v58:[updateContainedMemberOrCandidate]
[UpdateTracker:9782732] Update Tracker - [Pathway:8850843] Phosphate bond hydrolysis by NTPDase proteins - v58:[updateContainedRLE]
[UpdateTracker:9894992] Update Tracker - [Complex:6804885] p-S166,S188-MDM2 dimer, p-S166,S188-MDM2,MDM4:TP53 [nucleoplasm] - v58:[modifyName, updateContainedComponent]
[UpdateTracker:9782935] Update Tracker - [Pathway:3065678] SUMO is transferred from E1 to E2 (UBE2I, UBC9) - v58:[updateContainedRLE]
[UpdateTracker:9894989] Update Tracker - [CandidateSet:8867746] SH3GLs [cytosol] - v58:[addName]
[UpdateTracker:9894930] Update Tracker - [Complex:8868626] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894856] Update Tracker - [Complex:381168] ATF6:BiP [endoplasmic reticulum membrane] - v58:[addName]
[UpdateTracker:9895022] Update Tracker - [EntityWithAccessionedSequence:381000] ATF6 [Golgi membrane] - v58:[addHasModifiedResidue]
[UpdateTracker:9782920] Update Tracker - [Reaction:1234163] Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha - v58:[addLiteratureReference, add_removeOutput]
[UpdateTracker:9894793] Update Tracker - [Complex:196124] STARD3:STARD3NL, STARD4,6:CHOL [cytosol] - v58:[modifyName, updateContainedComponent]
[UpdateTracker:9782892] Update Tracker - [BlackBoxEvent:443418] GP1b signaling involves c-Src - v58:[add_removeInput]
[UpdateTracker:9782806] Update Tracker - [Pathway:2404192] Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) - v58:[updateContainedRLE]
[UpdateTracker:9782997] Update Tracker - [Reaction:5672950] "Activator" RAF:YWHAB dimer binds RAS:GTP - v58:[modifyText]
[UpdateTracker:9894973] Update Tracker - [DefinedSet:1181129] p-Nodal Receptor [plasma membrane] - v58:[updateContainedMemberOrCandidate]
[UpdateTracker:9782899] Update Tracker - [Pathway:75955] RNA Polymerase II Transcription Elongation - v58:[updateIndirectRLE]
[UpdateTracker:9782752] Update Tracker - [BlackBoxEvent:381283] Expression of PPARG - v58:[addLiteratureReference, modifyText]
[UpdateTracker:9782789] Update Tracker - [Pathway:69278] Cell Cycle, Mitotic - v58:[updateContainedPathway]
[UpdateTracker:9782925] Update Tracker - [Pathway:189200] Cellular hexose transport - v58:[addHasEvent]
[UpdateTracker:9782805] Update Tracker - [Pathway:556833] Metabolism of lipids - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9782944] Update Tracker - [Pathway:5654736] Signaling by FGFR1 - v58:[updateContainedPathway]
[UpdateTracker:9782734] Update Tracker - [Reaction:430073] GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress - v58:[add_removeOutput]
[UpdateTracker:9782795] Update Tracker - [Pathway:5654228] Phospholipase C-mediated cascade; FGFR4 - v58:[removeHasEvent]
[UpdateTracker:9782800] Update Tracker - [Reaction:912790] CBL binds CRK - v58:[add_removeInput]
[UpdateTracker:9894888] Update Tracker - [SimpleEntity:113539] CH3COO- [mitochondrial matrix] - v58:[add_removeReferenceEntity, modifyName]
[UpdateTracker:9895017] Update Tracker - [EntityWithAccessionedSequence:167451] GNA13 [plasma membrane] - v58:[add_removeCompartment]
[UpdateTracker:9782877] Update Tracker - [Reaction:5686430] MUS81 binds EME1, EME2 - v58:[add_removeOutput]
[UpdateTracker:9782794] Update Tracker - [Reaction:1222384] Glutathione scavenges nitrosyl - v58:[modifyText]
[UpdateTracker:9782715] Update Tracker - [Pathway:5357801] Programmed Cell Death - v58:[modifyText, updateContainedPathway]
[UpdateTracker:9782902] Update Tracker - [Reaction:1181354] CERBERUS binds NODAL - v58:[add_removeInput]
[UpdateTracker:9782865] Update Tracker - [Reaction:3165230] SLC52A1,2,3 transport RIB from extracellular region to cytosol - v58:[addLiteratureReference, modifyText]
[UpdateTracker:9782927] Update Tracker - [Pathway:2262752] Cellular responses to stress - v58:[updateContainedPathway]
[UpdateTracker:9782708] Update Tracker - [Pathway:1655829] Regulation of cholesterol biosynthesis by SREBP (SREBF) - v58:[updateIndirectRLE]
[UpdateTracker:9894917] Update Tracker - [Complex:191813] Spliceosomal m7G capped snRNAs with SMN:SM protein complex bound [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9782739] Update Tracker - [Pathway:1222556] ROS and RNS production in phagocytes - v58:[addHasEvent, updateContainedRLE]
[UpdateTracker:9894933] Update Tracker - [DefinedSet:1181125] NODAL Receptor [plasma membrane] - v58:[updateContainedMemberOrCandidate]
[UpdateTracker:9894864] Update Tracker - [Complex:5368269] 28S ribosomal subunit:MTIF3 [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782963] Update Tracker - [Reaction:8851089] NTPDase2 hydrolyzes nucleoside triphosphates - v58:[add_removeInput]
[UpdateTracker:9894782] Update Tracker - [EntityWithAccessionedSequence:428463] SRGAP3 [cytosol] - v58:[addName]
[UpdateTracker:9894879] Update Tracker - [Complex:114596] Collagen type I fibril:vWF [extracellular region] - v58:[modifyName]
[UpdateTracker:9894799] Update Tracker - [Complex:377616] Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782773] Update Tracker - [Pathway:169911] Regulation of Apoptosis - v58:[addHasEvent]
[UpdateTracker:9782931] Update Tracker - [Pathway:198203] PI3K/AKT activation - v58:[updateContainedPathway]
[UpdateTracker:9894817] Update Tracker - [Complex:113719] Processive elongation complex [nucleoplasm] - v58:[addHasComponent]
[UpdateTracker:9894798] Update Tracker - [CandidateSet:1307798] Substrates of MIA40:ERV1 [mitochondrial intermembrane space] - v58:[addHasCandidate, addHasMember]
[UpdateTracker:9894927] Update Tracker - [Complex:182946] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane] - v58:[add_removeHasComponent]
[UpdateTracker:9782781] Update Tracker - [Pathway:5654716] Downstream signaling of activated FGFR4 - v58:[updateContainedPathway]
[UpdateTracker:9782840] Update Tracker - [Pathway:5654693] FRS-mediated FGFR1 signaling - v58:[removeHasEvent]
[UpdateTracker:9894844] Update Tracker - [Complex:3240771] EZH2 Gene:E2F1/2/3:DP1/2 [nucleoplasm] - v58:[updateContainedComponent]
[UpdateTracker:9782854] Update Tracker - [Pathway:425381] Bicarbonate transporters - v58:[addHasEvent, updateContainedRLE]
[UpdateTracker:9782767] Update Tracker - [Reaction:182994] Assembly of EGFR complex in clathrin-coated vesicles - v58:[add_removeInput, modifyText]
[UpdateTracker:9895004] Update Tracker - [Complex:6804999] p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4:TP53 [nucleoplasm] - v58:[modifyName, updateContainedComponent]
[UpdateTracker:9894854] Update Tracker - [Complex:1234125] hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol] - v58:[add_removeHasComponent, modifyName]
[UpdateTracker:9782988] Update Tracker - [Reaction:1222685] Cathelicidin LL-37 binds to bacterial cell wall - v58:[addInput, add_removeOutput, modifyText]
[UpdateTracker:9894857] Update Tracker - [Complex:5389851] 55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA:TUFM:GTP [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9895030] Update Tracker - [Complex:8868609] DNM:GDP [cytosol] - v58:[addHasComponent]
[UpdateTracker:9782917] Update Tracker - [Pathway:112316] Neuronal System - v58:[removeHasEvent, updateContainedPathway]
[UpdateTracker:9782718] Update Tracker - [Pathway:6804758] Regulation of TP53 Activity through Acetylation - v58:[addHasEvent]
[UpdateTracker:9894983] Update Tracker - [Complex:169143] NS1 dimer [cytosol] - v58:[addDisease]
[UpdateTracker:9782830] Update Tracker - [Pathway:168898] Toll-like Receptor Cascades - v58:[updateIndirectRLE]
[UpdateTracker:9782864] Update Tracker - [Pathway:2559580] Oxidative Stress Induced Senescence - v58:[add_removeHasEvent]
[UpdateTracker:9782957] Update Tracker - [Reaction:6813720] NCEH1 hydrolyzes cholesterol esters - v58:[add_removeInput, add_removeOutput, modifyText]
[UpdateTracker:9782824] Update Tracker - [Pathway:382551] Transport of small molecules - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9894955] Update Tracker - [Complex:3240767] EED Gene:E2F1/2/3:DP1/2 [nucleoplasm] - v58:[updateContainedComponent]
[UpdateTracker:9894928] Update Tracker - [Complex:422306] ADCY5,6,8:G-alpha(s):GTP [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782913] Update Tracker - [Pathway:983705] Signaling by the B Cell Receptor (BCR) - v58:[updateContainedPathway]
[UpdateTracker:9782890] Update Tracker - [Pathway:5223345] Miscellaneous transport and binding events - v58:[addHasEvent, updateContainedRLE]
[UpdateTracker:9894991] Update Tracker - [SimpleEntity:1130930] PYR [cytoplasm] - v58:[addName]
[UpdateTracker:9895008] Update Tracker - [CandidateSet:5674399] SUV420H1,SUV420H2,(SMYD3) [nucleoplasm] - v58:[add_removeHasMember, modifyName]
[UpdateTracker:9782736] Update Tracker - [Pathway:186712] Regulation of beta-cell development - v58:[updateIndirectRLE]
[UpdateTracker:9782821] Update Tracker - [Pathway:187037] Signaling by NTRK1 (TRKA) - v58:[updateContainedPathway]
[UpdateTracker:9894840] Update Tracker - [Complex:6811381] RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] - v58:[updateContainedComponent]
[UpdateTracker:9895027] Update Tracker - [Complex:2400008] PI3K Inhibitors:PI3K [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9782967] Update Tracker - [Pathway:70921] Histidine catabolism - v58:[addHasEvent]
[UpdateTracker:9782704] Update Tracker - [Pathway:1280215] Cytokine Signaling in Immune system - v58:[updateContainedPathway]
[UpdateTracker:9782894] Update Tracker - [Pathway:196819] Vitamin B1 (thiamin) metabolism - v58:[addHasEvent]
[UpdateTracker:9894855] Update Tracker - [CandidateSet:351660] SIN3A,(SIN3B) [nucleoplasm] - v58:[addName]
[UpdateTracker:9782842] Update Tracker - [Pathway:5633007] Regulation of TP53 Activity - v58:[updateContainedPathway]
[UpdateTracker:9894895] Update Tracker - [EntityWithAccessionedSequence:2980572] CHN2 [cytosol] - v58:[addName]
[UpdateTracker:9894832] Update Tracker - [Complex:1234103] ub-HIF-alpha:VHL:EloB,C:CUL2:RBX1 [nucleoplasm] - v58:[updateContainedComponent]
[UpdateTracker:9782960] Update Tracker - [Pathway:1168372] Downstream signaling events of B Cell Receptor (BCR) - v58:[updateContainedPathway]
[UpdateTracker:9782885] Update Tracker - [Reaction:163217] Complex I oxidises NADH to NAD+, reduces CoQ to QH2 - v58:[addLiteratureReference, addRegulator, modifyText]
[UpdateTracker:9782749] Update Tracker - [Pathway:212436] Generic Transcription Pathway - v58:[updateContainedPathway]
[UpdateTracker:9782866] Update Tracker - [Pathway:912631] Regulation of signaling by CBL - v58:[updateContainedRLE]
[UpdateTracker:9894910] Update Tracker - [Complex:197266] NMNAT2:Mg2+ [Golgi membrane] - v58:[addLiteratureReference, add_removeCompartment]
[UpdateTracker:9894967] Update Tracker - [EntityWithAccessionedSequence:1169439] p-Y194,Y195,Y272-SHC1-3 [plasma membrane] - v58:[modifyName]
[UpdateTracker:9894957] Update Tracker - [Complex:392844] Heterotrimeric G-protein Gs (active) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782859] Update Tracker - [Pathway:5654221] Phospholipase C-mediated cascade; FGFR2 - v58:[removeHasEvent]
[UpdateTracker:9894988] Update Tracker - [EntityWithAccessionedSequence:913472] RAPGEF1 [cytosol] - v58:[addName]
[UpdateTracker:9894823] Update Tracker - [EntityWithAccessionedSequence:1614439] FGFR4 Y367C [plasma membrane] - v58:[removeInferredFrom]
[UpdateTracker:9782926] Update Tracker - [Pathway:196843] Vitamin B2 (riboflavin) metabolism - v58:[updateContainedRLE]
[UpdateTracker:9782783] Update Tracker - [Pathway:5689896] Ovarian tumor domain proteases - v58:[addHasEvent]
[UpdateTracker:9782803] Update Tracker - [Pathway:3108232] SUMO E3 ligases SUMOylate target proteins - v58:[updateIndirectRLE]
[UpdateTracker:9782763] Update Tracker - [BlackBoxEvent:75097] Transport of the export-competent mRNP complex through the NPC - v58:[addLiteratureReference]
[UpdateTracker:9782711] Update Tracker - [Pathway:72200] mRNA Editing: C to U Conversion - v58:[updateIndirectRLE]
[UpdateTracker:9894774] Update Tracker - [Complex:422314] GLP1R:Heterotrimeric G(s):GDP [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782726] Update Tracker - [Pathway:5654695] PI-3K cascade:FGFR2 - v58:[removeHasEvent]
[UpdateTracker:9894946] Update Tracker - [Complex:169075] NS1:viral dsRNA Complex [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9782810] Update Tracker - [Pathway:5654696] Downstream signaling of activated FGFR2 - v58:[updateContainedPathway]
[UpdateTracker:9782762] Update Tracker - [Pathway:1181150] Signaling by NODAL - v58:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9782738] Update Tracker - [Pathway:977225] Amyloid fiber formation - v58:[addHasEvent]
[UpdateTracker:9782710] Update Tracker - [Pathway:2980736] Peptide hormone metabolism - v58:[updateIndirectRLE]
[UpdateTracker:9894985] Update Tracker - [Complex:1225915] NODAL:p-ACVR1C:ACVR2B:EGF-CFC [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782757] Update Tracker - [Pathway:1643685] Disease - v58:[addHasEvent, updateContainedPathway]
[UpdateTracker:9782879] Update Tracker - [Reaction:200512] NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD - v58:[add_removeInput, add_removeOutput]
[UpdateTracker:9894923] Update Tracker - [Complex:157594] CCNE:CDK2 [cytosol] - v58:[addName, updateContainedComponent]
[UpdateTracker:9782849] Update Tracker - [Pathway:5693568] Resolution of D-loop Structures through Holliday Junction Intermediates - v58:[updateContainedRLE]
[UpdateTracker:9894908] Update Tracker - [Complex:5389838] 55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894841] Update Tracker - [Complex:3209097] DP1/2: E2F1/2/3: SP1: CDKN2A Gene [nucleoplasm] - v58:[updateContainedComponent]
[UpdateTracker:9782860] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v58:[updateContainedPathway]
[UpdateTracker:9782834] Update Tracker - [Pathway:1368108] BMAL1:CLOCK,NPAS2 activates circadian gene expression - v58:[addHasEvent, updateContainedRLE]
[UpdateTracker:9894780] Update Tracker - [DefinedSet:6804745] p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm] - v58:[add_removeHasMember, modifyName]
[UpdateTracker:9782748] Update Tracker - [Pathway:5654700] FRS-mediated FGFR2 signaling - v58:[removeHasEvent]
[UpdateTracker:9894836] Update Tracker - [Complex:354176] Talin:RIAM complex [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782980] Update Tracker - [Reaction:429529] Thrombin binding to GP1b:IX:V - v58:[add_removeInput]
[UpdateTracker:9782919] Update Tracker - [Reaction:8848580] DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG - v58:[modifyText]
[UpdateTracker:9894819] Update Tracker - [Complex:391179] Heterotrimeric G-protein Gs (inactive) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894954] Update Tracker - [Complex:422311] GLP-1:GLP-1R:Heterotrimeric G(s):GTP [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894861] Update Tracker - [Complex:191762] SMN complex [nucleoplasm] - v58:[addHasComponent, addLiteratureReference]
[UpdateTracker:9894883] Update Tracker - [Complex:8871145] PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782928] Update Tracker - [Pathway:76009] Platelet Aggregation (Plug Formation) - v58:[updateContainedRLE]
[UpdateTracker:9894937] Update Tracker - [Complex:744890] GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9783000] Update Tracker - [BlackBoxEvent:188345] The CDC25A gene transcription is stimulated by MYC and E2F1 and inhibited by the DREAM complex - v58:[addInput, add_removeRegulator, modifyText]
[UpdateTracker:9782714] Update Tracker - [Reaction:5617143] B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA - v58:[add_removeInput, add_removeOutput]
[UpdateTracker:9782923] Update Tracker - [Pathway:1483191] Synthesis of PC - v58:[addHasEvent]
[UpdateTracker:9782751] Update Tracker - [Pathway:1234158] Regulation of gene expression by Hypoxia-inducible Factor - v58:[addHasEvent]
[UpdateTracker:9782906] Update Tracker - [Pathway:72202] Transport of Mature Transcript to Cytoplasm - v58:[updateIndirectRLE]
[UpdateTracker:9782985] Update Tracker - [Pathway:196849] Metabolism of water-soluble vitamins and cofactors - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9895009] Update Tracker - [Complex:976093] RBX1-CUL2-EloB,C-VHL [cytosol] - v58:[addLiteratureReference]
[UpdateTracker:9782764] Update Tracker - [Reaction:216723] 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane - v58:[modifyText]
[UpdateTracker:9894980] Update Tracker - [Complex:751015] Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782827] Update Tracker - [BlackBoxEvent:1362408] FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster - v58:[addLiteratureReference]
[UpdateTracker:9782922] Update Tracker - [Pathway:5673000] RAF activation - v58:[updateContainedRLE]
[UpdateTracker:9894929] Update Tracker - [Complex:354079] Focal Adhesion/Focal contacts [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782934] Update Tracker - [Pathway:549127] Organic cation transport - v58:[updateContainedRLE]
[UpdateTracker:9894834] Update Tracker - [Complex:429434] Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782918] Update Tracker - [Pathway:1234174] Cellular response to hypoxia - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9782876] Update Tracker - [Pathway:8868773] rRNA processing in the nucleus and cytosol - v58:[updateIndirectRLE]
[UpdateTracker:9894787] Update Tracker - [Complex:8867751] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782799] Update Tracker - [Pathway:597592] Post-translational protein modification - v58:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9782818] Update Tracker - [Pathway:373760] L1CAM interactions - v58:[addHasEvent]
[UpdateTracker:9782900] Update Tracker - [Pathway:209952] Peptide hormone biosynthesis - v58:[updateIndirectRLE]
[UpdateTracker:9782828] Update Tracker - [Reaction:5340130] CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol - v58:[addLiteratureReference, modifyText]
[UpdateTracker:9782863] Update Tracker - [BlackBoxEvent:1368140] Expression of PPARGC1A (PGC-1alpha) - v58:[add_removeRegulator]
[UpdateTracker:9782785] Update Tracker - [Pathway:192105] Synthesis of bile acids and bile salts - v58:[addHasEvent]
[UpdateTracker:9894839] Update Tracker - [CandidateSet:5672717] RAF/MAPK scaffolds [cytosol] - v58:[updateContainedMemberOrCandidate]
[UpdateTracker:9894878] Update Tracker - [Complex:201427] p-2S-SMAD1/5/8:SMAD4:SKI [nucleoplasm] - v58:[add_removeHasComponent]
[UpdateTracker:9894892] Update Tracker - [Complex:1181141] ACVR1C:ACVR2B:EGF-CFC [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782758] Update Tracker - [Pathway:200425] Carnitine metabolism - v58:[addHasEvent, updateContainedRLE]
[UpdateTracker:9894867] Update Tracker - [Complex:354113] GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782772] Update Tracker - [Reaction:5617037] POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 - v58:[add_removeInput, add_removeOutput, modifyText]
[UpdateTracker:9782905] Update Tracker - [Reaction:8851356] NTPDase5 hydrolyzes nucleoside diphosphates - v58:[add_removeInput]
[UpdateTracker:9782940] Update Tracker - [BlackBoxEvent:422088] Expression of Preproghrelin - v58:[addRegulator]
[UpdateTracker:9782937] Update Tracker - [Pathway:3232118] SUMOylation of transcription factors - v58:[updateContainedRLE]
[UpdateTracker:9782774] Update Tracker - [Pathway:5654720] PI-3K cascade:FGFR4 - v58:[removeHasEvent]
[UpdateTracker:9895012] Update Tracker - [Complex:1225883] NODAL:p-ACVR1B:ACVR2:EGF-CFC [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9895016] Update Tracker - [Complex:113721] Arrested processive elongation complex [nucleoplasm] - v58:[addHasComponent]
[UpdateTracker:9894870] Update Tracker - [Complex:8866261] EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782753] Update Tracker - [Pathway:209822] Glycoprotein hormones - v58:[updateContainedRLE]
[UpdateTracker:9782880] Update Tracker - [Pathway:168249] Innate Immune System - v58:[add_removeHasEvent]
[UpdateTracker:9894863] Update Tracker - [Complex:5686474] SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) [nucleoplasm] - v58:[add_removeHasComponent, modifyName]
[UpdateTracker:9782727] Update Tracker - [Pathway:168164] Toll Like Receptor 3 (TLR3) Cascade - v58:[updateIndirectRLE]
[UpdateTracker:9782882] Update Tracker - [Reaction:166175] TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) - v58:[modifyText]
[UpdateTracker:9895024] Update Tracker - [EntityWithAccessionedSequence:2980571] CHN1 [cytosol] - v58:[addName]
[UpdateTracker:9782929] Update Tracker - [Reaction:425483] SLC4A5,7,9 cotransport Na+ with 3HCO3- - v58:[modifyText, removeLiteratureReference]
[UpdateTracker:9782771] Update Tracker - [Reaction:197235] NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD - v58:[add_removeInput, add_removeOutput, modifyText]
[UpdateTracker:9894940] Update Tracker - [DefinedSet:4827375] WHSC1, NSD1, SMYD2, ASH1L [nucleoplasm] - v58:[addHasMember, modifyName]
[UpdateTracker:9782911] Update Tracker - [Pathway:159418] Recycling of bile acids and salts - v58:[addHasEvent]
[UpdateTracker:9894850] Update Tracker - [Complex:8868627] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782815] Update Tracker - [Pathway:1483226] Synthesis of PI - v58:[addHasEvent]
[UpdateTracker:9782717] Update Tracker - [Pathway:196807] Nicotinate metabolism - v58:[updateContainedRLE]
[UpdateTracker:9782713] Update Tracker - [Reaction:381309] PPARG:RXRA heterodimer binds to fatty acid-like ligands - v58:[addInput]
[UpdateTracker:9782870] Update Tracker - [Pathway:1433557] Signaling by SCF-KIT - v58:[updateContainedPathway]
[UpdateTracker:9894859] Update Tracker - [Complex:443399] GPIb-IX-V:vWF:14-3-3-zeta:p85 [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782737] Update Tracker - [Pathway:381119] Unfolded Protein Response (UPR) - v58:[addLiteratureReference, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9782948] Update Tracker - [Pathway:1236394] Signaling by ERBB4 - v58:[updateContainedPathway]
[UpdateTracker:9782790] Update Tracker - [Pathway:69202] Cyclin E associated events during G1/S transition - v58:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9782993] Update Tracker - [Pathway:199991] Membrane Trafficking - v58:[addHasEvent]
[UpdateTracker:9894960] Update Tracker - [DefinedSet:5672601] RAS GEFs [plasma membrane] - v58:[addHasMember]
[UpdateTracker:9782924] Update Tracker - [Pathway:1433617] Regulation of signaling by NODAL - v58:[updateContainedRLE]
[UpdateTracker:9894886] Update Tracker - [Complex:5419272] 55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782874] Update Tracker - [Pathway:198323] AKT phosphorylates targets in the cytosol - v58:[updateContainedRLE]
[UpdateTracker:9782706] Update Tracker - [Pathway:418346] Platelet homeostasis - v58:[addHasEvent]
[UpdateTracker:9782759] Update Tracker - [Pathway:77111] Synthesis of Ketone Bodies - v58:[addHasEvent]
[UpdateTracker:9894939] Update Tracker - [Complex:556812] Pparg:Fatty Acid:Rxra:Mediator:coactivator Complex [nucleoplasm] - v58:[addHasComponent, addLiteratureReference]
[UpdateTracker:9894993] Update Tracker - [EntityWithAccessionedSequence:6784669] CREB3L3 [endoplasmic reticulum membrane] - v58:[addName]
[UpdateTracker:9782966] Update Tracker - [Pathway:425397] Transport of vitamins, nucleosides, and related molecules - v58:[updateIndirectRLE]
[UpdateTracker:9894890] Update Tracker - [Complex:354135] Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894921] Update Tracker - [Complex:1227905] E2F1,E2F2,E2F3:TFDP1,TFDP2 [nucleoplasm] - v58:[add_removeHasComponent, modifyName, updateContainedComponent]
[UpdateTracker:9782893] Update Tracker - [Pathway:6791226] Major pathway of rRNA processing in the nucleolus and cytosol - v58:[updateContainedRLE]
[UpdateTracker:9782770] Update Tracker - [Pathway:5654227] Phospholipase C-mediated cascade; FGFR3 - v58:[removeHasEvent]
[UpdateTracker:9782833] Update Tracker - [Pathway:3215018] Processing and activation of SUMO - v58:[updateIndirectRLE]
[UpdateTracker:9782970] Update Tracker - [BlackBoxEvent:211289] MAFA-, NKX2-2-, PAX6-, and PDX1-dependent synthesis of insulin precursor protein - v58:[addInput, addRegulator]
[UpdateTracker:9782873] Update Tracker - [Reaction:196126] CHOL translocates from cytosol to mitochondrial intermembrane space - v58:[add_removeLiteratureReference, modifyText]
[UpdateTracker:9894868] Update Tracker - [DefinedSet:8868710] CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] - v58:[updateContainedMemberOrCandidate]
[UpdateTracker:9782733] Update Tracker - [Pathway:182971] EGFR downregulation - v58:[addHasEvent, updateContainedRLE]
[UpdateTracker:9782909] Update Tracker - [Reaction:5672973] MAP2Ks phosphorylate MAPKs - v58:[modifyText]
[UpdateTracker:9894808] Update Tracker - [Complex:1176067] NS1 homodimer:Importin [nucleoplasm] - v58:[addDisease]
[UpdateTracker:9782868] Update Tracker - [Pathway:388396] GPCR downstream signalling - v58:[updateIndirectRLE]
[UpdateTracker:9894838] Update Tracker - [Complex:113724] Elongation complex prior to separation [nucleoplasm] - v58:[addHasComponent]
[UpdateTracker:9782856] Update Tracker - [Pathway:5669034] TNFs bind their physiological receptors - v58:[addHasEvent]
[UpdateTracker:9894866] Update Tracker - [CandidateSet:976075] E3 ligases in proteasomal degradation [cytosol] - v58:[updateContainedMemberOrCandidate]
[UpdateTracker:9894944] Update Tracker - [Complex:8868624] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894966] Update Tracker - [Complex:114668] GPIb-IX-V [plasma membrane] - v58:[modifyName]
[UpdateTracker:9894919] Update Tracker - [EntityWithAccessionedSequence:381222] ATF6 [endoplasmic reticulum membrane] - v58:[addHasModifiedResidue]
[UpdateTracker:9894920] Update Tracker - [Complex:354110] Rap1-GTP:PIP2:RIAM [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782723] Update Tracker - [Pathway:114604] GPVI-mediated activation cascade - v58:[updateContainedRLE]
[UpdateTracker:9782809] Update Tracker - [Reaction:113429] Elongating transcript encounters a lesion in the template - v58:[addOutput]
[UpdateTracker:9894904] Update Tracker - [Complex:164384] G-protein with G(s) alpha:GDP [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782852] Update Tracker - [Pathway:5688426] Deubiquitination - v58:[updateContainedPathway]
[UpdateTracker:9782846] Update Tracker - [Pathway:196071] Metabolism of steroid hormones - v58:[updateIndirectRLE]
[UpdateTracker:9782768] Update Tracker - [Pathway:71291] Metabolism of amino acids and derivatives - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9894869] Update Tracker - [Complex:398146] G-protein alpha (12/13):LARG:Plexin B1 [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782953] Update Tracker - [Pathway:422475] Axon guidance - v58:[updateContainedPathway]
[UpdateTracker:9782952] Update Tracker - [Reaction:428262] phytoceramide + H2O => stearate + phytosphingosine - v58:[add_removeOutput]
[UpdateTracker:9782968] Update Tracker - [BlackBoxEvent:8864431] TFAP2A,TFAP2C homodimers stimulate CGB3 gene expression - v58:[add_removeOutput, modifyText]
[UpdateTracker:9782801] Update Tracker - [Pathway:159236] Transport of Mature mRNA derived from an Intron-Containing Transcript - v58:[updateContainedRLE]
[UpdateTracker:9782700] Update Tracker - [BlackBoxEvent:1234175] ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol - v58:[addLiteratureReference, modifyText]
[UpdateTracker:9894958] Update Tracker - [Complex:377619] Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782901] Update Tracker - [Pathway:77286] mitochondrial fatty acid beta-oxidation of saturated fatty acids - v58:[updateContainedPathway]
[UpdateTracker:9895018] Update Tracker - [Complex:354074] RAP1:GDP [plasma membrane] - v58:[add_removeHasComponent, modifyName, updateContainedComponent]
[UpdateTracker:9894907] Update Tracker - [DefinedSet:8866252] ubiquitinated cargo [plasma membrane] - v58:[addHasMember]
[UpdateTracker:9782936] Update Tracker - [Reaction:549279] OCT2 mediates tubular uptake of organic cations in the kidney - v58:[addLiteratureReference, addRegulator, modifyText]
[UpdateTracker:9782836] Update Tracker - [Pathway:1482788] Acyl chain remodelling of PC - v58:[addHasEvent]
[UpdateTracker:9894796] Update Tracker - [Complex:354157] Vinculin bound to alphaIIbbeta3 [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894853] Update Tracker - [Complex:1181134] NODAL:p-NODAL Receptor [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782729] Update Tracker - [Pathway:69656] Cyclin A:Cdk2-associated events at S phase entry - v58:[updateContainedRLE]
[UpdateTracker:9894935] Update Tracker - [Complex:182931] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:SPRY1/2:Endophilin:Epsin:Eps15L1:EPS15 [plasma membrane] - v58:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9782721] Update Tracker - [Pathway:15869] Metabolism of nucleotides - v58:[updateIndirectRLE]
[UpdateTracker:9894918] Update Tracker - [Complex:983134] E3:K48-polyubiquitinated substrate [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9782735] Update Tracker - [Pathway:416482] G alpha (12/13) signalling events - v58:[updateContainedRLE]
[UpdateTracker:9895023] Update Tracker - [Complex:1181346] LEFTY1,2:NODAL Receptor [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894848] Update Tracker - [DefinedSet:425547] SLC4A5,7,9 [plasma membrane] - v58:[modifyName, removeHasMember]
[UpdateTracker:9782969] Update Tracker - [Pathway:1234176] Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha - v58:[updateContainedRLE]
[UpdateTracker:9894898] Update Tracker - [EntityWithAccessionedSequence:428453] SRGAP1 [cytosol] - v58:[addName]
[UpdateTracker:9894807] Update Tracker - [Complex:983131] E3:Ub:substrate [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9894785] Update Tracker - [Complex:392864] Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894852] Update Tracker - [Complex:77606] Editosome for C to U editing [nucleoplasm] - v58:[add_removeHasComponent]
[UpdateTracker:9782812] Update Tracker - [Pathway:430116] GP1b-IX-V activation signalling - v58:[updateContainedRLE]
[UpdateTracker:9894995] Update Tracker - [EntityWithAccessionedSequence:916821] B4GAT1 [Golgi membrane] - v58:[addName]
[UpdateTracker:9895003] Update Tracker - [Complex:68653] E2F1:TFDP1,TFDP2 [nucleoplasm] - v58:[add_removeHasComponent, modifyName]
[UpdateTracker:9782844] Update Tracker - [BlackBoxEvent:927813] p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A - v58:[addInput, addLiteratureReference, modifyText]
[UpdateTracker:9782895] Update Tracker - [Reaction:442273] VAV1 is a GEF for Rho/Rac family GTPases - v58:[addRegulator]
[UpdateTracker:9894860] Update Tracker - [Complex:5419267] 55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782744] Update Tracker - [Pathway:5654219] Phospholipase C-mediated cascade: FGFR1 - v58:[removeHasEvent]
[UpdateTracker:9782977] Update Tracker - [Pathway:168256] Immune System - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9894812] Update Tracker - [Complex:1234138] ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] - v58:[modifyName, updateContainedComponent]
[UpdateTracker:9894835] Update Tracker - [Complex:397884] Thrombin activated PAR:G12/13 (active) [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782808] Update Tracker - [Pathway:427601] Multifunctional anion exchangers - v58:[addHasEvent]
[UpdateTracker:9894797] Update Tracker - [Complex:432187] AVPR2:AVP:G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782956] Update Tracker - [BlackBoxEvent:381186] ATF6 (ATF6-alpha) translocates from the endoplasmic reticulum to the Golgi - v58:[modifyText]
[UpdateTracker:9894778] Update Tracker - [Complex:432200] G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894931] Update Tracker - [EntityWithAccessionedSequence:1433476] p-Y194,Y195,Y272-SHC1-3 [cytosol] - v58:[modifyName]
[UpdateTracker:9782742] Update Tracker - [Reaction:159101] NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) - v58:[addLiteratureReference]
[UpdateTracker:9782788] Update Tracker - [Pathway:5654687] Downstream signaling of activated FGFR1 - v58:[updateContainedPathway]
[UpdateTracker:9782984] Update Tracker - [Pathway:75094] Formation of the Editosome - v58:[updateContainedRLE]
[UpdateTracker:9782941] Update Tracker - [Pathway:425407] SLC-mediated transmembrane transport - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9782971] Update Tracker - [Pathway:1227986] Signaling by ERBB2 - v58:[add_removeHasEvent, updateContainedPathway]
[UpdateTracker:9894881] Update Tracker - [Complex:983245] Kinesins:microtubule [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9782976] Update Tracker - [Reaction:69195] Phosphorylation of Cyclin E:CDK2 complexes by WEE1 - v58:[addLiteratureReference]
[UpdateTracker:9894813] Update Tracker - [Complex:8868234] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894777] Update Tracker - [EntityWithAccessionedSequence:2197548] HES1 gene [nucleoplasm] - v58:[modifyName]
[UpdateTracker:9782798] Update Tracker - [Reaction:2426163] SREBP1A,2 binds the CYP51A1 promoter - v58:[add_removeInput]
[UpdateTracker:9782791] Update Tracker - [Pathway:75876] Synthesis of very long-chain fatty acyl-CoAs - v58:[addHasEvent]
[UpdateTracker:9894825] Update Tracker - [Complex:164333] G alpha (s):GDP [plasma membrane] - v58:[add_removeHasComponent]
[UpdateTracker:9782869] Update Tracker - [Pathway:69275] G2/M Transition - v58:[addHasEvent]
[UpdateTracker:9782720] Update Tracker - [Pathway:2559585] Oncogene Induced Senescence - v58:[add_removeHasEvent]
[UpdateTracker:9894903] Update Tracker - [Complex:912774] p(Y700,731,774)-CBL:CRK [cytosol] - v58:[add_removeHasComponent]
[UpdateTracker:9782731] Update Tracker - [Pathway:879518] Transport of organic anions - v58:[updateContainedRLE]
[UpdateTracker:9782949] Update Tracker - [Pathway:1483257] Phospholipid metabolism - v58:[updateContainedPathway]
[UpdateTracker:9782778] Update Tracker - [Pathway:1483166] Synthesis of PA - v58:[addHasEvent]
[UpdateTracker:9782811] Update Tracker - [Reaction:3234081] SUMOylation of TFAP2A with SUMO1 - v58:[addLiteratureReference, modifyText]
[UpdateTracker:9894956] Update Tracker - [Complex:381367] PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] - v58:[addHasComponent]
[UpdateTracker:9894900] Update Tracker - [EntityWithAccessionedSequence:5617087] GlcNAc,1,2-Man-DAG1 [Golgi lumen] - v58:[add_removeCompartment, modifyName]
[UpdateTracker:9894872] Update Tracker - [EntityWithAccessionedSequence:996748] ZFPM1 [nucleoplasm] - v58:[addName]
[UpdateTracker:9782712] Update Tracker - [Pathway:5653656] Vesicle-mediated transport - v58:[updateContainedPathway]
[UpdateTracker:9782904] Update Tracker - [Pathway:5654689] PI-3K cascade:FGFR1 - v58:[removeHasEvent]
[UpdateTracker:9782989] Update Tracker - [Pathway:453274] Mitotic G2-G2/M phases - v58:[updateContainedPathway]
[UpdateTracker:9894942] Update Tracker - [Complex:430243] Rap1-GTP:Raf1 [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782916] Update Tracker - [Reaction:200423] pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis - v58:[add_removeInput, add_removeOutput, modifyText]
[UpdateTracker:9894977] Update Tracker - [Complex:429424] Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894938] Update Tracker - [Complex:1181126] p-ACVR1C:ACVR2B:EGF-CFC [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782722] Update Tracker - [Reaction:556760] Pparg:Rxra heterodimer binds to fatty acids - v58:[addInput]
[UpdateTracker:9894788] Update Tracker - [Complex:182947] EPS15:HGS:STAM [cytosol] - v58:[addLiteratureReference, modifyName]
[UpdateTracker:9894821] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9895021] Update Tracker - [Complex:354168] GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782933] Update Tracker - [Reaction:5690043] Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA - v58:[addLiteratureReference, addRegulator, modifyText]
[UpdateTracker:9894781] Update Tracker - [Complex:1225912] NODAL:ACVR1C:ACVR2B:EGF-CFC [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894949] Update Tracker - [EntityWithAccessionedSequence:381211] ATF6(1-380) [nucleoplasm] - v58:[modifyEndCoordinate, modifyName]
[UpdateTracker:9894826] Update Tracker - [EntityWithAccessionedSequence:164387] GNAS2 [plasma membrane] - v58:[modifyName]
[UpdateTracker:9782964] Update Tracker - [Pathway:69206] G1/S Transition - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9782851] Update Tracker - [Pathway:380108] Chemokine receptors bind chemokines - v58:[removeHasEvent]
[UpdateTracker:9782855] Update Tracker - [Pathway:6804757] Regulation of TP53 Degradation - v58:[updateContainedRLE]
[UpdateTracker:9782853] Update Tracker - [Pathway:75105] Fatty acyl-CoA biosynthesis - v58:[updateContainedPathway, updateContainedRLE]
[UpdateTracker:9782858] Update Tracker - [Pathway:428643] Organic anion transporters - v58:[addHasEvent]
[UpdateTracker:9782750] Update Tracker - [Pathway:2730905] Role of LAT2/NTAL/LAB on calcium mobilization - v58:[updateContainedPathway]
[UpdateTracker:9895010] Update Tracker - [Complex:1181132] ACVR1B:ACVR2A,B:EGF-CFC [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894809] Update Tracker - [Complex:112433] Elongation complex [nucleoplasm] - v58:[addLiteratureReference, add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9894805] Update Tracker - [Complex:378941] Gonadotropin [extracellular region] - v58:[add_removeHasComponent]
[UpdateTracker:9895029] Update Tracker - [Complex:2426132] SREBP1A,2:NF-Y:SP1:CYP51A1 gene [nucleoplasm] - v58:[add_removeHasComponent]
[UpdateTracker:9782887] Update Tracker - [Pathway:5654710] PI-3K cascade:FGFR3 - v58:[removeHasEvent]
[UpdateTracker:9894858] Update Tracker - [SimpleEntity:742361] UDP-Xyl [Golgi lumen] - v58:[modifyName]
[UpdateTracker:9894806] Update Tracker - [EntityWithAccessionedSequence:5615647] Man-DAG1 [endoplasmic reticulum lumen] - v58:[add_removeCompartment, modifyName]
[UpdateTracker:9782982] Update Tracker - [Pathway:76002] Platelet activation, signaling and aggregation - v58:[updateIndirectRLE]
[UpdateTracker:9894987] Update Tracker - [Complex:1225875] NODAL:ACVR1B:ACVR2A,B:EGF-CFC [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894970] Update Tracker - [Complex:5368239] 28S ribosomal subunit [mitochondrial inner membrane] - v58:[addHasComponent, addLiteratureReference]
[UpdateTracker:9782871] Update Tracker - [Pathway:2151201] Transcriptional activation of mitochondrial biogenesis - v58:[updateContainedRLE]
[UpdateTracker:9894887] Update Tracker - [Complex:6804995] p14ARF:p-S166,S188-MDM2 dimer,p-S166,S188-MDM2:MDM4 [nucleoplasm] - v58:[modifyName, updateContainedComponent]
[UpdateTracker:9894962] Update Tracker - [Complex:1181133] NODAL Ligand:NODAL Receptor [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894951] Update Tracker - [Complex:8868620] PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] - v58:[updateContainedComponent]
[UpdateTracker:9895013] Update Tracker - [Complex:5672720] activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894829] Update Tracker - [Complex:5368280] 28S ribosomal subunit:MTIF3:MTIF2:GTP:mRNA:fMet-tRNA [mitochondrial inner membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894875] Update Tracker - [Complex:191778] Spliceosomal m3G capped snRNA:SMN:SM:Snurportin complex [cytosol] - v58:[updateContainedComponent]
[UpdateTracker:9895005] Update Tracker - [DefinedSet:879625] SLCOs, SLC16A2 dimer [plasma membrane] - v58:[addHasMember, modifyName]
[UpdateTracker:9782838] Update Tracker - [Pathway:428157] Sphingolipid metabolism - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9782914] Update Tracker - [Pathway:75109] Triglyceride biosynthesis - v58:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9894911] Update Tracker - [Complex:8868634] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894791] Update Tracker - [Complex:5672724] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894882] Update Tracker - [EntityWithAccessionedSequence:1637900] FGFR2 K660E [plasma membrane] - v58:[removeInferredFrom]
[UpdateTracker:9894884] Update Tracker - [Complex:8868232] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9782998] Update Tracker - [Pathway:74160] Gene expression (Transcription) - v58:[updateContainedPathway]
[UpdateTracker:9894824] Update Tracker - [Complex:2197638] SCARF1:Ligand [plasma membrane] - v58:[updateContainedComponent]
[UpdateTracker:9894902] Update Tracker - [Complex:435464] GpIb-IX-V:Collagen type I fibril:vWF [plasma membrane] - v58:[modifyName, updateContainedComponent]

Cite Us!