Reactome | 66 on 2018-09-30

Schema > Release > Entries

66 on 2018-09-30 Show undefined attributes

dbId	9778969
displayName	66 on 2018-09-30
modified	[InstanceEdit:9982963] Weiser, Joel, 2026-02-20
releaseDate	2018-09-30
releaseNumber	66
schemaClass	Release

Referrals

(release)

[UpdateTracker:9899595] Update Tracker - [Complex:5624943] active kinesin-2 motors [cilium] - v66:[updateContainedComponent]
[UpdateTracker:9779103] Update Tracker - [BlackBoxEvent:75869] Addition of the fourth nucleotide on the Nascent Transcript: Second Transition - v66:[removeCatalystActivity]
[UpdateTracker:9779181] Update Tracker - [Pathway:3371453] Regulation of HSF1-mediated heat shock response - v66:[updateContainedRLE]
[UpdateTracker:9779031] Update Tracker - [Pathway:2142691] Synthesis of Leukotrienes (LT) and Eoxins (EX) - v66:[updateContainedRLE]
[UpdateTracker:9779172] Update Tracker - [Reaction:193845] CYP8B1 12-hydroxylates 4CHOL7a,27DONE - v66:[add_removeOutput]
[UpdateTracker:9899491] Update Tracker - [Complex:166360] p-3S,3T-IRAK1:p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v66:[modifyName, updateContainedComponent]
[UpdateTracker:9899488] Update Tracker - [Complex:8982725] Alpha-polyglutamylated microtubule [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899417] Update Tracker - [Complex:751015] Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9899509] Update Tracker - [Complex:8867419] Polyglutamyl alpha-beta tubulin dimer [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9778975] Update Tracker - [Reaction:376149] Proteolytic processing of SLIT - v66:[modifyText]
[UpdateTracker:9779244] Update Tracker - [Pathway:438066] Unblocking of NMDA receptors, glutamate binding and activation - v66:[addHasEvent, add_removeLiteratureReference, modifyText, updateContainedRLE]
[UpdateTracker:9779160] Update Tracker - [Reaction:114544] p115-RhoGEF activation of RHOA - v66:[add_removeInput, add_removeLiteratureReference, add_removeOutput, modifyText]
[UpdateTracker:9779281] Update Tracker - [Reaction:399712] Activation of Ca permeable AMPA receptors - v66:[removeInput, removeOutput]
[UpdateTracker:9899400] Update Tracker - [Complex:983245] Kinesins:microtubule [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899387] Update Tracker - [DefinedSet:2399923] AKT inhibitors [cytosol] - v66:[add_removeHasMember]
[UpdateTracker:9779193] Update Tracker - [Pathway:399710] Activation of AMPA receptors - v66:[updateContainedRLE]
[UpdateTracker:9899415] Update Tracker - [Complex:180738] RAN:GTP [nucleoplasm] - v66:[addName]
[UpdateTracker:9779150] Update Tracker - [Reaction:421139] Limk1 phosphorylates Cfl1, inactivating it - v66:[addOutput]
[UpdateTracker:9778976] Update Tracker - [Reaction:379842] Dimerization of p-S133-Creb1 - v66:[addLiteratureReference, modifyText]
[UpdateTracker:9899513] Update Tracker - [Complex:5632741] DDIT4:14-3-3 dimer [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899562] Update Tracker - [EntityWithAccessionedSequence:4755487] SUMO1-K132,K289-NR1H4 [nucleoplasm] - v66:[addHasModifiedResidue, modifyName]
[UpdateTracker:9779048] Update Tracker - [Pathway:1169410] Antiviral mechanism by IFN-stimulated genes - v66:[addHasEvent]
[UpdateTracker:9899428] Update Tracker - [Complex:5618323] Ac K40 alpha tubulin:GTP [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899493] Update Tracker - [DefinedSet:2077416] Tyrosine kinase inhibitors of FGFR3 mutants [cytosol] - v66:[addHasMember]
[UpdateTracker:9779009] Update Tracker - [Pathway:500792] GPCR ligand binding - v66:[updateContainedPathway]
[UpdateTracker:9779105] Update Tracker - [Reaction:2399992] AKT1 E17K mutant phosphorylates forkhead box transcription factors - v66:[add_removeOutput, modifyText]
[UpdateTracker:9899557] Update Tracker - [Complex:8943070] TMEM129:DERL1:VIMP:VCP:UBE2J2 [endoplasmic reticulum membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779216] Update Tracker - [Pathway:111933] Calmodulin induced events - v66:[updateIndirectRLE]
[UpdateTracker:9779020] Update Tracker - [Pathway:69278] Cell Cycle, Mitotic - v66:[removeHasEvent]
[UpdateTracker:9779042] Update Tracker - [Reaction:195408] NRP-1 forms a ternary complex with VEGF165 and VEGFR1 - v66:[modifyText]
[UpdateTracker:9899574] Update Tracker - [Complex:190017] botA LC:Zn2+ [cytosol] - v66:[add_removeHasComponent]
[UpdateTracker:9899396] Update Tracker - [Complex:209660] pre-miRNA:RAN:GTP:Exportin-5 [nucleoplasm] - v66:[updateContainedComponent]
[UpdateTracker:9778974] Update Tracker - [Pathway:5663205] Infectious disease - v66:[updateContainedPathway]
[UpdateTracker:9899570] Update Tracker - [Complex:445022] AP2 clathrin:L1:KIF4:microtubule [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779261] Update Tracker - [Pathway:69206] G1/S Transition - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9779201] Update Tracker - [Pathway:74752] Signaling by Insulin receptor - v66:[modifyText, updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9779026] Update Tracker - [Pathway:5252538] Drosophila signaling pathways - v66:[updateContainedPathway]
[UpdateTracker:9779197] Update Tracker - [Pathway:156827] L13a-mediated translational silencing of Ceruloplasmin expression - v66:[updateContainedRLE]
[UpdateTracker:9899533] Update Tracker - [DefinedSet:189644] Ntrk1,2,3 [Golgi membrane] - v66:[addName]
[UpdateTracker:9778997] Update Tracker - [Pathway:75955] RNA Polymerase II Transcription Elongation - v66:[updateIndirectRLE]
[UpdateTracker:9779269] Update Tracker - [Reaction:209148] Murine CKIalpha binds to Murine Axin1 - v66:[addSummation]
[UpdateTracker:9899564] Update Tracker - [Complex:180719] Importin-beta:Ran GTP complex [nucleoplasm] - v66:[updateContainedComponent]
[UpdateTracker:9779079] Update Tracker - [Pathway:73857] RNA Polymerase II Transcription - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9899408] Update Tracker - [Complex:190509] alpha-tubulin:GTP [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899507] Update Tracker - [EntityWithAccessionedSequence:190053] RAP1A [endosome membrane] - v66:[add_removeCompartment]
[UpdateTracker:9779134] Update Tracker - [Pathway:211994] Sterols are 12-hydroxylated by CYP8B1 - v66:[updateContainedRLE]
[UpdateTracker:9779119] Update Tracker - [Reaction:209144] Human APC is finally phosphorylated by Murine GSK3beta - v66:[addSummation]
[UpdateTracker:9779068] Update Tracker - [Reaction:390674] ADRB1 bind ADR,NAd - v66:[addRegulator, add_removeInput, modifyText]
[UpdateTracker:9899596] Update Tracker - [Complex:5625410] active dynein-2 motors [ciliary tip] - v66:[updateContainedComponent]
[UpdateTracker:9899455] Update Tracker - [DefinedSet:187658] NTRK1,2 [Golgi membrane] - v66:[addName]
[UpdateTracker:9899573] Update Tracker - [Complex:190083] Activated TrkA receptor complex [endosome membrane] - v66:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9779210] Update Tracker - [Pathway:69202] Cyclin E associated events during G1/S transition - v66:[updateContainedRLE]
[UpdateTracker:9899425] Update Tracker - [Complex:937018] IRAK1:p-S,2T-IRAK4 :oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v66:[modifyName, updateContainedComponent]
[UpdateTracker:9779130] Update Tracker - [Pathway:3108232] SUMO E3 ligases SUMOylate target proteins - v66:[updateIndirectRLE]
[UpdateTracker:9779174] Update Tracker - [Reaction:432162] Unblocking of GRIN1:GRIN2 NMDA receptors - v66:[add_removeInput, add_removeOutput, modifyText, removeLiteratureReference]
[UpdateTracker:9779151] Update Tracker - [Reaction:189632] Adcyap1 binds Adcyap1r1 and Ntrk1,2,3 - v66:[add_removeOutput, modifyText]
[UpdateTracker:9779276] Update Tracker - [Pathway:9020558] Interleukin-2 signaling - v66:[updateContainedRLE]
[UpdateTracker:9779290] Update Tracker - [Reaction:167019] SHC, complexed with TrkA, is tyrosine-phosphorylated - v66:[addInput, addOutput]
[UpdateTracker:9899391] Update Tracker - [Complex:75005] p-S216-CDC25C:14-3-3 protein complex [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779287] Update Tracker - [Reaction:2976563] NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter - v66:[add_removeInput]
[UpdateTracker:9779003] Update Tracker - [Pathway:194315] Signaling by Rho GTPases - v66:[modifyText]
[UpdateTracker:9899599] Update Tracker - [Complex:389873] AGTR2:AGT(34-41) [plasma membrane] - v66:[modifyName]
[UpdateTracker:9899399] Update Tracker - [Complex:2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - v66:[updateContainedComponent]
[UpdateTracker:9779044] Update Tracker - [Reaction:156832] INF-gamma induced phosphorylation of L13a - v66:[addInput, addOutput]
[UpdateTracker:9899508] Update Tracker - [Complex:5624947] retrograde IFT trains [cilium] - v66:[updateContainedComponent]
[UpdateTracker:9899379] Update Tracker - [Complex:391236] beta tubulin:GTP: Cofactor D:alpha tubulin:GTP:Cofactor E [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779084] Update Tracker - [Reaction:156673] Regulation of KIF23 (MKLP1) by phosphorylation - v66:[addInput, addOutput]
[UpdateTracker:9779252] Update Tracker - [Pathway:913531] Interferon Signaling - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9779224] Update Tracker - [Reaction:114542] RAC1,RAC2,RHOG activate PI3K - v66:[add_removeInput]
[UpdateTracker:9899444] Update Tracker - [Complex:8867390] Polyglycyl alpha-beta tubulin dimer [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779143] Update Tracker - [Reaction:156699] Inactivation of Wee1 kinase - v66:[addInput, addOutput]
[UpdateTracker:9899406] Update Tracker - [Complex:391248] alpha-beta heterodimer [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899419] Update Tracker - [Complex:190046] botA LC:Zn2+ [extracellular region] - v66:[add_removeHasComponent]
[UpdateTracker:9778973] Update Tracker - [Pathway:451308] Activation of Ca-permeable Kainate Receptor - v66:[updateContainedRLE]
[UpdateTracker:9899487] Update Tracker - [Complex:5672333] RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779238] Update Tracker - [Pathway:1592230] Mitochondrial biogenesis - v66:[updateIndirectRLE]
[UpdateTracker:9779021] Update Tracker - [Pathway:111446] Activation of BIM and translocation to mitochondria - v66:[updateContainedRLE]
[UpdateTracker:9779059] Update Tracker - [Pathway:187024] NGF-independant TRKA activation - v66:[addHasEvent, updateContainedRLE]
[UpdateTracker:9779124] Update Tracker - [Pathway:983705] Signaling by the B Cell Receptor (BCR) - v66:[updateContainedPathway]
[UpdateTracker:9899569] Update Tracker - [Complex:182087] p-S,T-Raf1 [cytosol] - v66:[modifyName]
[UpdateTracker:9899427] Update Tracker - [DefinedSet:2316432] Activator:PI3K [plasma membrane] - v66:[addHasMember]
[UpdateTracker:9779088] Update Tracker - [Pathway:69242] S Phase - v66:[updateIndirectRLE]
[UpdateTracker:9778995] Update Tracker - [Reaction:209059] Murine CKIepsilon binds to Murine Axin1 - v66:[addSummation]
[UpdateTracker:9778994] Update Tracker - [Pathway:73779] RNA Polymerase II Transcription Pre-Initiation And Promoter Opening - v66:[modifyText]
[UpdateTracker:9899548] Update Tracker - [Complex:2201325] activated TLR2/4:p-4Y-TIRAP:PI(4,5)P2:BTK [plasma membrane] - v66:[addName]
[UpdateTracker:9779247] Update Tracker - [Pathway:162791] Attachment of GPI anchor to uPAR - v66:[modifyText]
[UpdateTracker:9899520] Update Tracker - [Complex:190556] connexons in Golgi transport vesicle docked to microtubules [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779090] Update Tracker - [Pathway:114452] Activation of BH3-only proteins - v66:[updateIndirectRLE]
[UpdateTracker:9779062] Update Tracker - [Reaction:8948143] p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 - v66:[addInput, addOutput]
[UpdateTracker:9779228] Update Tracker - [Pathway:5576893] Phase 2 - plateau phase - v66:[updateContainedRLE]
[UpdateTracker:9779036] Update Tracker - [Reaction:622325] Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors - v66:[removeInput, removeOutput]
[UpdateTracker:9779126] Update Tracker - [Pathway:977225] Amyloid fiber formation - v66:[addHasEvent]
[UpdateTracker:9778990] Update Tracker - [Pathway:5205647] Mitophagy - v66:[updateIndirectRLE]
[UpdateTracker:9779239] Update Tracker - [Reaction:4719413] PIAS2,3,4 SUMOylate RORA with SUMO2 - v66:[add_removeCatalystActivity, modifyText]
[UpdateTracker:9778983] Update Tracker - [Reaction:169895] Crk's SH3 domain engages C3G - v66:[modifyText]
[UpdateTracker:9779275] Update Tracker - [Pathway:68884] Mitotic Telophase/Cytokinesis - v66:[updateContainedRLE]
[UpdateTracker:9779117] Update Tracker - [Pathway:451306] Ionotropic activity of kainate receptors - v66:[updateIndirectRLE]
[UpdateTracker:9899607] Update Tracker - [DefinedSet:391243] alpha/beta tubulin folding intermediate [cytosol] - v66:[updateContainedMemberOrCandidate]
[UpdateTracker:9899582] Update Tracker - [Polymer:8867460] Polyglutamyl microtubule protofilament [cytosol] - v66:[updateContainedRepeatedUnit]
[UpdateTracker:9899526] Update Tracker - [Complex:390643] ADRB1:ADR,NAd [plasma membrane] - v66:[add_removeHasComponent, modifyName]
[UpdateTracker:9778971] Update Tracker - [Pathway:622323] Presynaptic nicotinic acetylcholine receptors - v66:[updateIndirectRLE]
[UpdateTracker:9779158] Update Tracker - [Pathway:597592] Post-translational protein modification - v66:[updateContainedPathway]
[UpdateTracker:9899516] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9899409] Update Tracker - [Polymer:8867406] Polyglycylated microtubule protofilament [cytosol] - v66:[updateContainedRepeatedUnit]
[UpdateTracker:9899376] Update Tracker - [Complex:5228950] botA HC:LC dimer [synaptic vesicle membrane] - v66:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9779038] Update Tracker - [Reaction:432232] Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) - v66:[addInput, addOutput]
[UpdateTracker:9779198] Update Tracker - [Reaction:110237] MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine - v66:[modifyText]
[UpdateTracker:9779271] Update Tracker - [Pathway:453279] Mitotic G1 phase and G1/S transition - v66:[updateContainedPathway]
[UpdateTracker:9899518] Update Tracker - [Complex:5228948] botA HC:LC dimer [plasma membrane] - v66:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9899555] Update Tracker - [DefinedSet:380110] Ligand:GPCR complexes that activate Gq/11 [plasma membrane] - v66:[updateContainedMemberOrCandidate]
[UpdateTracker:9779069] Update Tracker - [Pathway:451927] Interleukin-2 family signaling - v66:[updateIndirectRLE]
[UpdateTracker:9899553] Update Tracker - [Complex:3928570] Glu:NMDAR:Gly [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779049] Update Tracker - [Pathway:168274] Export of Viral Ribonucleoproteins from Nucleus - v66:[updateIndirectRLE]
[UpdateTracker:9899502] Update Tracker - [Complex:751030] ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9899552] Update Tracker - [Complex:391235] GTP-alpha-tubulin folding intermediate [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779081] Update Tracker - [Reaction:170991] SRC-1 autophosphorylates - v66:[addRegulator, add_removeInput, add_removeOutput, modifyText]
[UpdateTracker:9779194] Update Tracker - [Pathway:982772] Growth hormone receptor signaling - v66:[updateContainedRLE]
[UpdateTracker:9779203] Update Tracker - [Pathway:68881] Mitotic Metaphase/Anaphase Transition - v66:[updateContainedRLE]
[UpdateTracker:9779142] Update Tracker - [Pathway:194138] Signaling by VEGF - v66:[modifyText, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9899566] Update Tracker - [CandidateSet:8867459] Polyglutamyl alpha tubulin [cytosol] - v66:[add_removeHasCandidate]
[UpdateTracker:9899375] Update Tracker - [Complex:165556] Crm1:Ran GTPase:GTP [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779092] Update Tracker - [Pathway:192105] Synthesis of bile acids and bile salts - v66:[updateIndirectRLE]
[UpdateTracker:9779146] Update Tracker - [Reaction:156723] Regulation of KIF20A (MKL2) by phosphorylation - v66:[addInput, addOutput]
[UpdateTracker:9899560] Update Tracker - [SimpleEntity:29968] L-Cit [cytosol] - v66:[addName]
[UpdateTracker:9899511] Update Tracker - [Complex:180718] RanBP1:Ran-GTP:CRM1:Rev-bound mRNA complex [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779159] Update Tracker - [Pathway:72737] Cap-dependent Translation Initiation - v66:[updateIndirectRLE]
[UpdateTracker:9899474] Update Tracker - [Polymer:8982429] acetylated microtubule protofilament [cytosol] - v66:[updateContainedRepeatedUnit]
[UpdateTracker:9779225] Update Tracker - [Reaction:73722] Phosphorylation of UBF-1:rDNA Promoter - v66:[addOutput]
[UpdateTracker:9779274] Update Tracker - [Reaction:193821] 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one - v66:[add_removeInput]
[UpdateTracker:9778988] Update Tracker - [Pathway:1222538] Tolerance by Mtb to nitric oxide produced by macrophages - v66:[updateContainedRLE]
[UpdateTracker:9899418] Update Tracker - [Complex:2029966] Overexpressed FGFR2:TKIs [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779133] Update Tracker - [Pathway:156711] Polo-like kinase mediated events - v66:[updateContainedRLE]
[UpdateTracker:9779110] Update Tracker - [Reaction:508282] SYK is a substrate for JAK1 - v66:[addInput, addOutput]
[UpdateTracker:9899471] Update Tracker - [Complex:8852295] GTSE1:MAPRE1:microtubule plus end [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779018] Update Tracker - [Pathway:2151201] Transcriptional activation of mitochondrial biogenesis - v66:[updateContainedRLE]
[UpdateTracker:9779051] Update Tracker - [BlackBoxEvent:190065] Activated TrkA receptor internalizes to endosomes - v66:[addLiteratureReference, modifyText]
[UpdateTracker:9899480] Update Tracker - [Complex:8955720] alpha-tubulinY:GTP [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779047] Update Tracker - [Pathway:69656] Cyclin A:Cdk2-associated events at S phase entry - v66:[updateContainedRLE]
[UpdateTracker:9899501] Update Tracker - [DefinedSet:2029965] Tyrosine kinase inhibitors of overexpressed FGFR2 [cytosol] - v66:[addHasMember]
[UpdateTracker:9779251] Update Tracker - [Pathway:168799] Neurotoxicity of clostridium toxins - v66:[updateIndirectRLE]
[UpdateTracker:9899538] Update Tracker - [Complex:375303] Microtubule-bound kinetochore [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899542] Update Tracker - [DefinedSet:189643] Adcyap1r1 [Golgi membrane] - v66:[addName]
[UpdateTracker:9899581] Update Tracker - [Polymer:5610520] microtubule [axonemal microtubule] - v66:[updateContainedRepeatedUnit]
[UpdateTracker:9899546] Update Tracker - [Complex:114540] RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] - v66:[add_removeHasComponent, modifyName]
[UpdateTracker:9779096] Update Tracker - [Pathway:1266695] Interleukin-7 signaling - v66:[updateContainedRLE]
[UpdateTracker:9899431] Update Tracker - [DefinedSet:391247] alpha-tubulin folding intermediate [cytosol] - v66:[add_removeHasMember]
[UpdateTracker:9779118] Update Tracker - [Reaction:163010] Down Regulation of Emi1 through Phosphorylation of Emi1 - v66:[addInput, addOutput]
[UpdateTracker:9779033] Update Tracker - [Pathway:109582] Hemostasis - v66:[updateContainedPathway]
[UpdateTracker:9899579] Update Tracker - [Complex:187653] Ade-Rib:ADORA2A:NTRK1,2 [Golgi membrane] - v66:[addHasComponent, modifyName]
[UpdateTracker:9899426] Update Tracker - [Complex:390495] actin/tubulin-bound CCT/TRiC:ADP [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779125] Update Tracker - [Reaction:379832] CaMKIV phosphorylates Creb1 - v66:[modifyText]
[UpdateTracker:9899597] Update Tracker - [Complex:190077] RAP1:GDP [endosome membrane] - v66:[add_removeCompartment, add_removeHasComponent, modifyName]
[UpdateTracker:9779043] Update Tracker - [Reaction:1250315] Trans-autophosphorylation of ERBB4 homodimers - v66:[modifyText]
[UpdateTracker:9779132] Update Tracker - [Pathway:1222499] Latent infection - Other responses of Mtb to phagocytosis - v66:[updateIndirectRLE]
[UpdateTracker:9899580] Update Tracker - [EntityWithAccessionedSequence:189636] Ntrk2 [Golgi membrane] - v66:[addName]
[UpdateTracker:9779262] Update Tracker - [Pathway:73927] Depurination - v66:[updateIndirectRLE]
[UpdateTracker:9779243] Update Tracker - [Pathway:69275] G2/M Transition - v66:[updateIndirectRLE]
[UpdateTracker:9779161] Update Tracker - [Pathway:187037] Signaling by NTRK1 (TRKA) - v66:[updateContainedPathway]
[UpdateTracker:9899386] Update Tracker - [Complex:6811381] RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] - v66:[updateContainedComponent]
[UpdateTracker:9779250] Update Tracker - [Pathway:112315] Transmission across Chemical Synapses - v66:[updateContainedPathway]
[UpdateTracker:9779147] Update Tracker - [Reaction:5694441] CSNK1D phosphorylates SEC23 - v66:[addInput, addOutput]
[UpdateTracker:9779279] Update Tracker - [Reaction:3371567] DBC1 is phosphorylated by ATM/ART - v66:[addInput, addOutput]
[UpdateTracker:9899478] Update Tracker - [Complex:750994] Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9899522] Update Tracker - [Complex:432217] p-S256-AQP2 tetramer [transport vesicle membrane] - v66:[modifyName]
[UpdateTracker:9899598] Update Tracker - [Complex:391241] Cofactor B:GTP-alpha tubulin [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779101] Update Tracker - [Pathway:1296053] Classical Kir channels - v66:[updateContainedRLE]
[UpdateTracker:9779222] Update Tracker - [Reaction:420980] Activation of Ca permeable AMPA receptors - v66:[removeInput, removeOutput]
[UpdateTracker:9779140] Update Tracker - [Reaction:187678] ADCYAP1(2-742) binds ADCYAP1R1 and NTRK1,2 - v66:[add_removeOutput, modifyText, removeCatalystActivity]
[UpdateTracker:9899602] Update Tracker - [DefinedSet:390461] Unfolded alpha/beta tubulin [cytosol] - v66:[add_removeHasMember]
[UpdateTracker:9779098] Update Tracker - [Pathway:350431] Planar Cell Polarity pathway - v66:[modifyText]
[UpdateTracker:9779085] Update Tracker - [Reaction:109822] MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 - v66:[addInput, addOutput]
[UpdateTracker:9899590] Update Tracker - [EntityWithAccessionedSequence:1015684] RNASEL [cytosol] - v66:[addName]
[UpdateTracker:9899504] Update Tracker - [Complex:5610522] alpha tubulin:GTP [axonemal microtubule] - v66:[updateContainedComponent]
[UpdateTracker:9779070] Update Tracker - [Pathway:198693] AKT phosphorylates targets in the nucleus - v66:[updateContainedRLE]
[UpdateTracker:9779073] Update Tracker - [Pathway:1296065] Inwardly rectifying K+ channels - v66:[updateIndirectRLE]
[UpdateTracker:9779155] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9899402] Update Tracker - [DefinedSet:390670] ADRB1,2,3 [plasma membrane] - v66:[modifyName]
[UpdateTracker:9779145] Update Tracker - [Pathway:110478] Insulin signaling pathway - v66:[updateContainedRLE]
[UpdateTracker:9899380] Update Tracker - [EntityWithAccessionedSequence:189625] Ntrk3 [Golgi membrane] - v66:[addName]
[UpdateTracker:9779010] Update Tracker - [Pathway:1268020] Mitochondrial protein import - v66:[addLiteratureReference, modifyText]
[UpdateTracker:9899456] Update Tracker - [CandidateSet:190587] alpha-tubulin [cytosol] - v66:[add_removeHasCandidate]
[UpdateTracker:9779131] Update Tracker - [Reaction:442760] Activation of RasGRF - v66:[add_removeInput]
[UpdateTracker:9779221] Update Tracker - [Reaction:199299] AKT phosphorylates FOXO transcription factors - v66:[addLiteratureReference, add_removeOutput, modifyText]
[UpdateTracker:9779235] Update Tracker - [Pathway:442720] CREB1 phosphorylation through the activation of Adenylate Cyclase - v66:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9779249] Update Tracker - [Reaction:1977959] ERBB4 forms heterodimers with EGFR - v66:[modifyText]
[UpdateTracker:9779091] Update Tracker - [Pathway:4085377] SUMOylation of SUMOylation proteins - v66:[updateContainedRLE]
[UpdateTracker:9899577] Update Tracker - [CandidateSet:8867415] Polyglycyl alpha tubulin [cytosol] - v66:[add_removeHasCandidate]
[UpdateTracker:9779185] Update Tracker - [BlackBoxEvent:5244428] botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol - v66:[add_removeOutput]
[UpdateTracker:9899401] Update Tracker - [Complex:391242] Cofactor E:GTP-alpha tubulin folding [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899397] Update Tracker - [DefinedSet:751003] Ligand:GPCR complexes that activate G12/13 [plasma membrane] - v66:[updateContainedMemberOrCandidate]
[UpdateTracker:9779254] Update Tracker - [Pathway:1222541] Cell redox homeostasis - v66:[updateContainedRLE]
[UpdateTracker:9779100] Update Tracker - [Pathway:162906] HIV Infection - v66:[modifyText]
[UpdateTracker:9779283] Update Tracker - [Pathway:445717] Aquaporin-mediated transport - v66:[updateIndirectRLE]
[UpdateTracker:9779148] Update Tracker - [Reaction:429016] ALOX5 is phosphorylated by MAPKAP2 - v66:[addInput, addOutput]
[UpdateTracker:9899404] Update Tracker - [Complex:2559411] TIRAP:PI(4,5)P2:activated TLR2/4 [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779297] Update Tracker - [Reaction:2201322] TIRAP is phosphorylated by BTK - v66:[addInput, addOutput]
[UpdateTracker:9779214] Update Tracker - [Pathway:1643685] Disease - v66:[addHasEvent, updateContainedPathway]
[UpdateTracker:9779208] Update Tracker - [Pathway:73856] RNA Polymerase II Transcription Termination - v66:[modifyText]
[UpdateTracker:9899463] Update Tracker - [Complex:190073] Active TrkA receptor:p-FRS2 complex [endosome membrane] - v66:[add_removeCompartment, add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9779285] Update Tracker - [Reaction:909726] Phosphorylation of STAT1 - v66:[addOutput]
[UpdateTracker:9779094] Update Tracker - [Reaction:8948039] FUNDC1 is phosphorylated by CK2 - v66:[addInput, addOutput]
[UpdateTracker:9779093] Update Tracker - [Reaction:4085350] SUMOylation of UBE2I with SUMO1 - v66:[modifyText]
[UpdateTracker:9899446] Update Tracker - [Complex:1445126] Phospho AS160:14-3-3 [cytoplasmic vesicle membrane] - v66:[updateContainedComponent]
[UpdateTracker:9899490] Update Tracker - [Complex:5578721] IPO8:RAN:GTP [nucleoplasm] - v66:[updateContainedComponent]
[UpdateTracker:9899460] Update Tracker - [Complex:8852286] GTSE1:microtubule [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899452] Update Tracker - [DefinedSet:390664] ADRA2A,B,C [plasma membrane] - v66:[modifyName]
[UpdateTracker:9899430] Update Tracker - [Complex:2262714] YWHAQ dimer [cytosol] - v66:[addName]
[UpdateTracker:9779012] Update Tracker - [Pathway:187042] TRKA activation by NGF - v66:[updateContainedRLE]
[UpdateTracker:9899472] Update Tracker - [Complex:190036] botA LC:Zn2+ [synaptic vesicle membrane] - v66:[add_removeHasComponent]
[UpdateTracker:9779173] Update Tracker - [Pathway:169893] Prolonged ERK activation events - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9779241] Update Tracker - [Reaction:139908] Phosphorylation of DLC2 by MAPK8 - v66:[addInput, addOutput]
[UpdateTracker:9899495] Update Tracker - [Complex:5624921] Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] - v66:[updateContainedComponent]
[UpdateTracker:9899385] Update Tracker - [Polymer:8955868] Alpha-polyglutamyl microtubule protofilament [cytosol] - v66:[updateContainedRepeatedUnit]
[UpdateTracker:9779064] Update Tracker - [Pathway:76042] RNA Polymerase II Transcription Initiation And Promoter Clearance - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9899544] Update Tracker - [CandidateSet:8955570] detyr-alpha-tubulin [cytosol] - v66:[add_removeHasCandidate]
[UpdateTracker:9778986] Update Tracker - [Reaction:168880] vRNP Export through the nuclear pore - v66:[add_removeInput]
[UpdateTracker:9899551] Update Tracker - [Complex:389876] AGTR1:AGT(34-41) [plasma membrane] - v66:[add_removeHasComponent, modifyName]
[UpdateTracker:9899453] Update Tracker - [Complex:2077404] FGFR2 point mutant dimers:TKIs [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9899403] Update Tracker - [Complex:2400006] AKT inhibitors:AKT [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899393] Update Tracker - [Complex:166281] pp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v66:[modifyName, updateContainedComponent]
[UpdateTracker:9779164] Update Tracker - [Pathway:512988] Interleukin-3, Interleukin-5 and GM-CSF signaling - v66:[updateContainedRLE]
[UpdateTracker:9899475] Update Tracker - [Complex:9037685] MyD88 variant:TIRAP:BTK:activated TLR2/4 [plasma membrane] - v66:[addName, updateContainedComponent]
[UpdateTracker:9899558] Update Tracker - [EntityWithAccessionedSequence:182075] Raf1 [cytosol] - v66:[modifyName]
[UpdateTracker:9779087] Update Tracker - [Reaction:432172] Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor - v66:[add_removeInput, add_removeOutput, modifyText, removeLiteratureReference]
[UpdateTracker:9779034] Update Tracker - [Pathway:190828] Gap junction trafficking - v66:[updateIndirectRLE]
[UpdateTracker:9779202] Update Tracker - [Pathway:163615] PKA activation - v66:[updateContainedRLE]
[UpdateTracker:9899482] Update Tracker - [Complex:749451] Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779067] Update Tracker - [Pathway:139910] Activation of BMF and translocation to mitochondria - v66:[updateContainedRLE]
[UpdateTracker:9899447] Update Tracker - [Complex:5625425] retrograde IFT trains [ciliary tip] - v66:[updateContainedComponent]
[UpdateTracker:9779137] Update Tracker - [Pathway:2586552] Signaling by Leptin - v66:[updateContainedRLE]
[UpdateTracker:9899407] Update Tracker - [Complex:390501] CCT/TRiC:ADP:non-native tubulin [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899479] Update Tracker - [Complex:1454696] p-S237-TBC1D1:14-3-3 [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779108] Update Tracker - [Reaction:170965] (Frs2)Rap1-GTP binds to and activates B-Raf - v66:[add_removeInput, removeCatalystActivity]
[UpdateTracker:9779204] Update Tracker - [Pathway:392518] Signal amplification - v66:[updateIndirectRLE]
[UpdateTracker:9779220] Update Tracker - [Reaction:1524186] Phosphorylation of PLCgamma by PDGFR - v66:[addInput, addOutput]
[UpdateTracker:9899378] Update Tracker - [Complex:984818] BLNK (SLP-65) Signalosome [plasma membrane] - v66:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9779015] Update Tracker - [Reaction:209132] Human APC is initially phosphorylated by Murine CKIepsilon - v66:[addSummation]
[UpdateTracker:9779072] Update Tracker - [Reaction:1181349] Phosphorylation of Smad2 by Nodal Receptor - v66:[addInput, addOutput]
[UpdateTracker:9899466] Update Tracker - [Complex:5610521] alpha-beta tubulin dimer [axonemal microtubule] - v66:[updateContainedComponent]
[UpdateTracker:9899593] Update Tracker - [Complex:2262716] SFN dimer [cytosol] - v66:[addName]
[UpdateTracker:9779237] Update Tracker - [Pathway:5250968] Toxicity of botulinum toxin type A (botA) - v66:[updateContainedRLE]
[UpdateTracker:9899514] Update Tracker - [Complex:937033] oligo-MyD88:TIRAP:BTK:activated TLR [plasma membrane] - v66:[modifyName, updateContainedComponent]
[UpdateTracker:9779152] Update Tracker - [Pathway:187015] Activation of TRKA receptors - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9899410] Update Tracker - [EntityWithAccessionedSequence:379806] p-S133-Creb1 [nucleoplasm] - v66:[modifyName]
[UpdateTracker:9899370] Update Tracker - [Complex:190075] B-Raf complex [cytosol] - v66:[add_removeCompartment, add_removeHasComponent]
[UpdateTracker:9779272] Update Tracker - [Reaction:9009236] Activated ERKs phosphorylate Runx2 - v66:[addInput, addOutput]
[UpdateTracker:9778987] Update Tracker - [BlackBoxEvent:74718] Internalisation of the insulin receptor - v66:[modifyText]
[UpdateTracker:9779014] Update Tracker - [Reaction:4341072] SUMOylation of RARA with SUMO2 - v66:[modifyText]
[UpdateTracker:9779029] Update Tracker - [Pathway:9006934] Signaling by Receptor Tyrosine Kinases - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9899528] Update Tracker - [EntityWithAccessionedSequence:189650] Ntrk1 [Golgi membrane] - v66:[addName]
[UpdateTracker:9779074] Update Tracker - [Reaction:451311] Activation of Ca-permeable Kainate receptors - v66:[removeInput, removeOutput]
[UpdateTracker:9899395] Update Tracker - [Complex:8982724] Polyglutamylated microtubule [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779253] Update Tracker - [Reaction:452102] p-STAT5 dimerizes - v66:[add_removeSummation, removeLiteratureReference]
[UpdateTracker:9899483] Update Tracker - [DefinedSet:5672601] RAS GEFs [plasma membrane] - v66:[updateContainedMemberOrCandidate]
[UpdateTracker:9899392] Update Tracker - [Complex:5624941] active dynein-2 motors [cilium] - v66:[updateContainedComponent]
[UpdateTracker:9899585] Update Tracker - [Complex:165531] Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP:NPC [nuclear envelope] - v66:[updateContainedComponent]
[UpdateTracker:9779032] Update Tracker - [Reaction:209146] Murine Axin1 is further phosphorylated by Human GSK3beta - v66:[addSummation]
[UpdateTracker:9899575] Update Tracker - [Complex:182108] Rap1-GTP:p-S,T-Raf1 [cytosol] - v66:[addHasComponent, modifyName, updateContainedComponent]
[UpdateTracker:9899374] Update Tracker - [Complex:8955573] detyr-alpha-tubulin:GTP [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9778985] Update Tracker - [Reaction:629595] Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors - v66:[removeInput, removeOutput]
[UpdateTracker:9779104] Update Tracker - [Reaction:74733] Insulin receptor de-phosphorylation - v66:[modifyText]
[UpdateTracker:9779050] Update Tracker - [Pathway:1980145] Signaling by NOTCH2 - v66:[updateIndirectRLE]
[UpdateTracker:9779071] Update Tracker - [Pathway:1251985] Nuclear signaling by ERBB4 - v66:[addLiteratureReference, modifyText, updateContainedRLE]
[UpdateTracker:9899429] Update Tracker - [Complex:2484902] Sister Centromere:Kinetochore:Microtubules [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779120] Update Tracker - [Reaction:189618] TrkA activation by adenosine A2a receptor - v66:[modifyText, removeOutput]
[UpdateTracker:9779123] Update Tracker - [Pathway:1430728] Metabolism - v66:[updateContainedPathway]
[UpdateTracker:9779076] Update Tracker - [Pathway:171007] p38MAPK events - v66:[updateContainedRLE]
[UpdateTracker:9899484] Update Tracker - [DefinedSet:187680] p-5Y-NTRK1, p-5Y-NTRK2 [Golgi membrane] - v66:[addName]
[UpdateTracker:9899421] Update Tracker - [Complex:189630] Ade-Rib:Adora2a:Ntrk1,2,3 [Golgi membrane] - v66:[addHasComponent, modifyName]
[UpdateTracker:9899537] Update Tracker - [Complex:444601] CAMK2 heteromer:CALM:4xCa2+ [plasma membrane] - v66:[add_removeHasComponent]
[UpdateTracker:9779186] Update Tracker - [Pathway:1640170] Cell Cycle - v66:[updateContainedPathway]
[UpdateTracker:9899554] Update Tracker - [Complex:3928507] GRIN1:GRIN2B di-heterotetramer [plasma membrane] - v66:[addName]
[UpdateTracker:9779295] Update Tracker - [Pathway:69306] DNA Replication - v66:[add_removeHasEvent]
[UpdateTracker:9779023] Update Tracker - [Pathway:74751] Insulin receptor signalling cascade - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9779264] Update Tracker - [Reaction:417829] P2RY12 binds ADP - v66:[addRegulator]
[UpdateTracker:9778982] Update Tracker - [Reaction:4719436] PIAS2,3,4 SUMOylate RORA with SUMO1 - v66:[add_removeCatalystActivity, modifyText]
[UpdateTracker:9899438] Update Tracker - [CandidateSet:5610524] alpha tubulin [axonemal microtubule] - v66:[add_removeHasCandidate]
[UpdateTracker:9779213] Update Tracker - [Reaction:110446] Phospho-Chico: Activated DINR binds p60:Dp110 - v66:[modifyText]
[UpdateTracker:9899588] Update Tracker - [Complex:190570] alpha-beta tubulin dimer [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779083] Update Tracker - [Reaction:77071] Phosphorylation (Ser5) of RNA pol II CTD - v66:[addInput, addOutput]
[UpdateTracker:9779257] Update Tracker - [Pathway:170968] Frs2-mediated activation - v66:[updateContainedRLE]
[UpdateTracker:9779211] Update Tracker - [Reaction:1296046] KCNJs transport K+ from the extracellular region to cytosol - v66:[add_removeInput, add_removeOutput]
[UpdateTracker:9899534] Update Tracker - [Complex:8849336] RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779278] Update Tracker - [Pathway:451307] Activation of Na-permeable kainate receptors - v66:[updateContainedRLE]
[UpdateTracker:9779260] Update Tracker - [Pathway:113510] E2F mediated regulation of DNA replication - v66:[modifyText]
[UpdateTracker:9899550] Update Tracker - [Complex:1445124] p-5S,T642-AS160:14-3-3:IRAP [cytoplasmic vesicle membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779218] Update Tracker - [Pathway:5250941] Negative epigenetic regulation of rRNA expression - v66:[updateIndirectRLE]
[UpdateTracker:9899489] Update Tracker - [Complex:5625414] active kinesin-2 motors [ciliary tip] - v66:[updateContainedComponent]
[UpdateTracker:9779236] Update Tracker - [Pathway:422475] Axon guidance - v66:[updateIndirectRLE]
[UpdateTracker:9779163] Update Tracker - [Pathway:167172] Transcription of the HIV genome - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9779011] Update Tracker - [Pathway:3371556] Cellular response to heat stress - v66:[updateIndirectRLE]
[UpdateTracker:9779157] Update Tracker - [Reaction:4341016] PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1 - v66:[modifyText]
[UpdateTracker:9779291] Update Tracker - [Pathway:629594] Highly calcium permeable postsynaptic nicotinic acetylcholine receptors - v66:[updateContainedRLE]
[UpdateTracker:9899498] Update Tracker - [Complex:2201331] TIRAP:PI(4,5)P2:BTK:activated TLR2/4 [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779267] Update Tracker - [Pathway:72613] Eukaryotic Translation Initiation - v66:[updateIndirectRLE]
[UpdateTracker:9899470] Update Tracker - [Complex:190070] Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] - v66:[add_removeCompartment, add_removeHasComponent, modifyName, updateContainedComponent]
[UpdateTracker:9899586] Update Tracker - [CandidateSet:2400011] PI3K mutants,Activator:PI3K [plasma membrane] - v66:[updateContainedMemberOrCandidate]
[UpdateTracker:9899539] Update Tracker - [Complex:2500242] p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - v66:[updateContainedComponent]
[UpdateTracker:9779028] Update Tracker - [Pathway:909733] Interferon alpha/beta signaling - v66:[updateContainedRLE]
[UpdateTracker:9779063] Update Tracker - [Reaction:169901] Rap1-GTP complex binds BRAF complex - v66:[add_removeOutput]
[UpdateTracker:9778998] Update Tracker - [Reaction:170964] FRS2 binds to active TrkA receptor - v66:[add_removeInput]
[UpdateTracker:9899377] Update Tracker - [Complex:390460] Prefoldin-associated actin/tubulin [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779058] Update Tracker - [Pathway:2142753] Arachidonic acid metabolism - v66:[updateIndirectRLE]
[UpdateTracker:9779288] Update Tracker - [Reaction:110246] Cleavage of adenine mispaired with 8-oxoguanine by MUTYH - v66:[modifyText]
[UpdateTracker:9779082] Update Tracker - [Pathway:392499] Metabolism of proteins - v66:[modifyText, removeHasEvent, updateContainedPathway]
[UpdateTracker:9899398] Update Tracker - [Complex:749455] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779265] Update Tracker - [Pathway:1236394] Signaling by ERBB4 - v66:[addLiteratureReference, modifyText, updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9779255] Update Tracker - [Pathway:397014] Muscle contraction - v66:[updateContainedPathway]
[UpdateTracker:9779016] Update Tracker - [Reaction:109823] MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 - v66:[addInput, addOutput]
[UpdateTracker:9778970] Update Tracker - [Reaction:5577213] LTCC multimer transports Ca2+ from extracellular region to cytosol - v66:[addRegulator]
[UpdateTracker:9779035] Update Tracker - [BlackBoxEvent:1252013] Translocation of ERBB4s80 to the nucleus - v66:[addLiteratureReference, addRegulator, modifyText]
[UpdateTracker:9899384] Update Tracker - [Complex:8849246] Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779231] Update Tracker - [Pathway:375280] Amine ligand-binding receptors - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9899373] Update Tracker - [Complex:380495] p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779183] Update Tracker - [Reaction:111916] Dimerization of p-S133-CREB1 - v66:[add_removeSummation]
[UpdateTracker:9779209] Update Tracker - [Pathway:376176] Signaling by ROBO receptors - v66:[updateContainedRLE]
[UpdateTracker:9779266] Update Tracker - [Pathway:163685] Integration of energy metabolism - v66:[modifyText]
[UpdateTracker:9778984] Update Tracker - [Pathway:1280215] Cytokine Signaling in Immune system - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9779169] Update Tracker - [Pathway:2219528] PI3K/AKT Signaling in Cancer - v66:[updateIndirectRLE]
[UpdateTracker:9779296] Update Tracker - [Pathway:110330] Recognition and association of DNA glycosylase with site containing an affected purine - v66:[updateContainedRLE]
[UpdateTracker:9779141] Update Tracker - [Reaction:451310] Activation of Edited Kainate receptors - v66:[removeInput, removeOutput]
[UpdateTracker:9899609] Update Tracker - [Complex:8955726] alphaY-beta tubulin dimer [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779045] Update Tracker - [Pathway:167162] RNA Polymerase II HIV Promoter Escape - v66:[addHasEvent, updateContainedRLE]
[UpdateTracker:9779176] Update Tracker - [Pathway:68886] M Phase - v66:[updateIndirectRLE]
[UpdateTracker:9779234] Update Tracker - [Pathway:2555396] Mitotic Metaphase and Anaphase - v66:[updateIndirectRLE]
[UpdateTracker:9899589] Update Tracker - [Complex:4755409] monoSUMO1-NR1H4:chenodeoxycholate [nucleoplasm] - v66:[addHasComponent, addLiteratureReference, modifyName]
[UpdateTracker:9899473] Update Tracker - [Complex:139904] 14-3-3 proteins:p-S99-BAD complex [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779162] Update Tracker - [Pathway:417957] P2Y receptors - v66:[updateContainedRLE]
[UpdateTracker:9779086] Update Tracker - [Pathway:198323] AKT phosphorylates targets in the cytosol - v66:[updateContainedRLE]
[UpdateTracker:9779054] Update Tracker - [Reaction:622326] Activation of highly calcium permeable nicotinic acetylcholine receptors - v66:[removeInput, removeOutput]
[UpdateTracker:9779263] Update Tracker - [Reaction:209060] Human APC is further phosphorylated by Murine GSK3beta - v66:[addSummation]
[UpdateTracker:9899547] Update Tracker - [Complex:190069] RAP1:GTP [endosome membrane] - v66:[add_removeCompartment, add_removeHasComponent, modifyName]
[UpdateTracker:9779230] Update Tracker - [Pathway:112314] Neurotransmitter receptors and postsynaptic signal transmission - v66:[removeHasEvent, updateContainedPathway]
[UpdateTracker:9779177] Update Tracker - [Reaction:4719447] PIAS2-2 SUMOylates THRA with SUMO1 - v66:[modifyText]
[UpdateTracker:9779240] Update Tracker - [Reaction:112381] Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex - v66:[addInput, addOutput]
[UpdateTracker:9899412] Update Tracker - [Complex:2213219] Kinesins:Dynactin:microtubule [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779061] Update Tracker - [Reaction:2065355] Secreted ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) - v66:[add_removeRegulator]
[UpdateTracker:9779111] Update Tracker - [Reaction:167098] Phosphorylation (Ser5) of RNA pol II CTD - v66:[addInput, addOutput]
[UpdateTracker:9779180] Update Tracker - [Pathway:977443] GABA receptor activation - v66:[addHasEvent]
[UpdateTracker:9899517] Update Tracker - [Complex:8852028] ADRB2:ADR,NAd [plasma membrane] - v66:[modifyName]
[UpdateTracker:9779156] Update Tracker - [Pathway:163125] Post-translational modification: synthesis of GPI-anchored proteins - v66:[updateContainedPathway]
[UpdateTracker:9779112] Update Tracker - [Reaction:1168636] p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP - v66:[addInput, addOutput]
[UpdateTracker:9779168] Update Tracker - [Pathway:442755] Activation of NMDA receptors and postsynaptic events - v66:[addHasEvent, addLiteratureReference, modifyText, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9899458] Update Tracker - [Complex:8982726] Polyglycylated microtubule [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779178] Update Tracker - [Reaction:162657] Inactivation of Myt1 kinase - v66:[addInput, addOutput]
[UpdateTracker:9779219] Update Tracker - [Reaction:198613] AKT phosphorylates p21Cip1 and p27Kip1 - v66:[addLiteratureReference]
[UpdateTracker:9899523] Update Tracker - [CandidateSet:5618321] acetylated alpha tubulin [cytosol] - v66:[add_removeHasCandidate]
[UpdateTracker:9779089] Update Tracker - [Reaction:111930] Adenylate cyclase produces cAMP - v66:[add_removeRegulator]
[UpdateTracker:9779075] Update Tracker - [Reaction:4719423] PIAS2-2 SUMOylates THRA with SUMO3 - v66:[modifyText]
[UpdateTracker:9779256] Update Tracker - [Pathway:186763] Downstream signal transduction - v66:[updateContainedRLE]
[UpdateTracker:9899568] Update Tracker - [Complex:937028] IRAK2:p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779121] Update Tracker - [Reaction:3968362] SUMOylation of PIAS4 with SUMO1 - v66:[modifyText]
[UpdateTracker:9899512] Update Tracker - [DefinedSet:199955] MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] - v66:[addName, add_removeHasMember]
[UpdateTracker:9779116] Update Tracker - [BlackBoxEvent:4755419] SUMOylation of NR1H4 with SUMO1 - v66:[addLiteratureReference, modifyText]
[UpdateTracker:9899411] Update Tracker - [DefinedSet:199878] p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] - v66:[add_removeHasMember, modifyName]
[UpdateTracker:9779259] Update Tracker - [Reaction:8939977] Activated AKT1 phosphorylates Runx2 - v66:[addInput, addOutput]
[UpdateTracker:9899450] Update Tracker - [Complex:391240] beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E : Cofactor C [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779192] Update Tracker - [Pathway:167152] Formation of HIV elongation complex in the absence of HIV Tat - v66:[updateContainedRLE]
[UpdateTracker:9899612] Update Tracker - [Complex:2077417] FGFR3 mutant dimers:TKIs [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779136] Update Tracker - [Reaction:2022405] ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) - v66:[removeRegulator]
[UpdateTracker:9779149] Update Tracker - [Pathway:73776] RNA Polymerase II Promoter Escape - v66:[addHasEvent, updateContainedRLE]
[UpdateTracker:9899549] Update Tracker - [Complex:2559415] TIRAP:PI(4,5)P2 [plasma membrane] - v66:[addName]
[UpdateTracker:9779188] Update Tracker - [Pathway:159782] Removal of aminoterminal propeptides from gamma-carboxylated proteins - v66:[modifyText]
[UpdateTracker:9899451] Update Tracker - [Complex:189642] Adcyap1:Adcyap1r1:p-Y-Ntrk1,2,3 [Golgi membrane] - v66:[addHasComponent, addName, updateContainedComponent]
[UpdateTracker:9899388] Update Tracker - [Complex:8867429] Polyglutamyl alpha tubulin:GTP [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779270] Update Tracker - [Reaction:1500781] Fgd1 reactivates F420 - v66:[add_removeInput, add_removeOutput]
[UpdateTracker:9899591] Update Tracker - [Complex:190599] Microtubule [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899437] Update Tracker - [Complex:194780] Docked Cx43-containing transport vesicles [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779206] Update Tracker - [Reaction:209065] Human APC is further phosphorylated by Murine CKIepsilon - v66:[addSummation]
[UpdateTracker:9899462] Update Tracker - [Complex:2262713] YWHAG dimer [cytosol] - v66:[addName]
[UpdateTracker:9779129] Update Tracker - [Pathway:112382] Formation of RNA Pol II elongation complex - v66:[updateContainedRLE]
[UpdateTracker:9899515] Update Tracker - [Complex:5244507] botA HC:LC dimer:SV2:GT1b [synaptic vesicle membrane] - v66:[updateContainedComponent]
[UpdateTracker:9778978] Update Tracker - [Reaction:5576895] SCNAs:SNCBs transport Na+ from extracellular region to cytosol - v66:[addRegulator]
[UpdateTracker:9899525] Update Tracker - [Complex:8852300] MAPRE1:microtubule plus end [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779280] Update Tracker - [Reaction:399711] Activation of Ca impermeable AMPA receptors - v66:[removeInput, removeOutput]
[UpdateTracker:9779106] Update Tracker - [Pathway:5576892] Phase 0 - rapid depolarisation - v66:[updateContainedRLE]
[UpdateTracker:9899530] Update Tracker - [EntityWithAccessionedSequence:1852607] miR-150 [cytosol] - v66:[addName]
[UpdateTracker:9778992] Update Tracker - [Reaction:427409] Nucleolar Remodelling Complex (NoRC) binds intergenic region of rDNA - v66:[addLiteratureReference, modifyText]
[UpdateTracker:9779223] Update Tracker - [Pathway:1257604] PIP3 activates AKT signaling - v66:[addHasEvent, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9899423] Update Tracker - [Complex:111904] p-S12.S13,T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] - v66:[add_removeHasComponent]
[UpdateTracker:9899603] Update Tracker - [CandidateSet:5624913] acetylated alpha tubulin [axonemal microtubule] - v66:[add_removeHasCandidate]
[UpdateTracker:9779102] Update Tracker - [Pathway:162599] Late Phase of HIV Life Cycle - v66:[updateContainedPathway]
[UpdateTracker:9779217] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v66:[updateIndirectRLE]
[UpdateTracker:9779030] Update Tracker - [Pathway:390696] Adrenoceptors - v66:[addHasEvent, updateContainedRLE]
[UpdateTracker:9899583] Update Tracker - [Complex:390700] ADRA2A,B,C:ADR,NAd [plasma membrane] - v66:[modifyName, updateContainedComponent]
[UpdateTracker:9779233] Update Tracker - [Pathway:416482] G alpha (12/13) signalling events - v66:[removeHasEvent, updateContainedRLE]
[UpdateTracker:9779242] Update Tracker - [Pathway:110331] Cleavage of the damaged purine - v66:[updateContainedRLE]
[UpdateTracker:9899459] Update Tracker - [Complex:379830] p-S133-Creb1 homodimer [nucleoplasm] - v66:[modifyName]
[UpdateTracker:9899576] Update Tracker - [Complex:111911] p-S133-CREB1 homodimer [nucleoplasm] - v66:[addName, removeHasComponent]
[UpdateTracker:9899543] Update Tracker - [Complex:170966] BRAF complex [cytosol] - v66:[modifyName]
[UpdateTracker:9779170] Update Tracker - [Pathway:193807] Synthesis of bile acids and bile salts via 27-hydroxycholesterol - v66:[updateContainedRLE]
[UpdateTracker:9779184] Update Tracker - [Reaction:438037] Membrane depolarization upon activation of Ca impermeable AMPA receptors - v66:[modifyText, removeInput, removeOutput]
[UpdateTracker:9899587] Update Tracker - [Complex:5624945] anterograde IFT trains [cilium] - v66:[updateContainedComponent]
[UpdateTracker:9899556] Update Tracker - [Complex:390457] tubulin-GTP folding intermediate [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779001] Update Tracker - [BlackBoxEvent:75850] Addition of the third nucleotide on the nascent transcript - v66:[removeCatalystActivity]
[UpdateTracker:9779144] Update Tracker - [Pathway:983695] Antigen activates B Cell Receptor (BCR) leading to generation of second messengers - v66:[add_removeHasEvent]
[UpdateTracker:9779189] Update Tracker - [Pathway:168333] NEP/NS2 Interacts with the Cellular Export Machinery - v66:[updateContainedRLE]
[UpdateTracker:9779052] Update Tracker - [BlackBoxEvent:190693] Synthesis of GJB1 (Cx32) - v66:[addInput]
[UpdateTracker:9899506] Update Tracker - [Complex:6783450] tRNA:XPOT:RAN:GTP [nucleoplasm] - v66:[updateContainedComponent]
[UpdateTracker:9779258] Update Tracker - [Pathway:2197563] NOTCH2 intracellular domain regulates transcription - v66:[updateContainedRLE]
[UpdateTracker:9779293] Update Tracker - [Pathway:5674400] Constitutive Signaling by AKT1 E17K in Cancer - v66:[updateContainedRLE]
[UpdateTracker:9778972] Update Tracker - [Pathway:438064] Post NMDA receptor activation events - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9779190] Update Tracker - [Pathway:1169092] Activation of RAS in B cells - v66:[updateContainedRLE]
[UpdateTracker:9778991] Update Tracker - [Pathway:194306] Neurophilin interactions with VEGF and VEGFR - v66:[modifyText, updateContainedRLE]
[UpdateTracker:9899420] Update Tracker - [Complex:983687] Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1 [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779046] Update Tracker - [Reaction:111919] PKA phosphorylates CREB1 - v66:[add_removeSummation]
[UpdateTracker:9899389] Update Tracker - [DefinedSet:2077403] Tyrosine kinase inhibitors of FGFR2 mutants [cytosol] - v66:[addHasMember]
[UpdateTracker:9779080] Update Tracker - [BlackBoxEvent:72647] Cap-bound mRNA is activated by helicases - v66:[removeCatalystActivity]
[UpdateTracker:9779109] Update Tracker - [Reaction:139918] Phosphorylation of BIM by JNK - v66:[addInput, addOutput]
[UpdateTracker:9899571] Update Tracker - [DefinedSet:1445138] 14-3-3 dimer [cytosol] - v66:[updateContainedMemberOrCandidate]
[UpdateTracker:9899529] Update Tracker - [Complex:166080] IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v66:[modifyName, updateContainedComponent]
[UpdateTracker:9778977] Update Tracker - [Pathway:418038] Nucleotide-like (purinergic) receptors - v66:[updateIndirectRLE]
[UpdateTracker:9899584] Update Tracker - [Complex:1638796] p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - v66:[updateContainedComponent]
[UpdateTracker:9779066] Update Tracker - [BlackBoxEvent:167113] Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition - v66:[removeCatalystActivity]
[UpdateTracker:9779039] Update Tracker - [Reaction:182065] Rap1-GTP binds Raf1 - v66:[add_removeOutput]
[UpdateTracker:9779060] Update Tracker - [Pathway:73728] RNA Polymerase I Promoter Opening - v66:[updateContainedRLE]
[UpdateTracker:9899468] Update Tracker - [Complex:744885] Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779113] Update Tracker - [Pathway:372790] Signaling by GPCR - v66:[updateContainedPathway]
[UpdateTracker:9899382] Update Tracker - [SimpleEntity:4419982] pPPP [integral component of cytoplasmic side of endoplasmic reticulum membrane] - v66:[addName]
[UpdateTracker:9899445] Update Tracker - [Complex:180686] RAN:GTP [cytosol] - v66:[modifyName]
[UpdateTracker:9779282] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v66:[modifyText]
[UpdateTracker:9779041] Update Tracker - [Pathway:75205] Dissolution of Fibrin Clot - v66:[modifyText]
[UpdateTracker:9899441] Update Tracker - [Complex:937053] TRAF6:hp-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v66:[modifyName, updateContainedComponent]
[UpdateTracker:9779268] Update Tracker - [Pathway:432040] Vasopressin regulates renal water homeostasis via Aquaporins - v66:[updateContainedRLE]
[UpdateTracker:9778979] Update Tracker - [Pathway:388396] GPCR downstream signalling - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9899561] Update Tracker - [Complex:5610559] KIF7:microtubule [ciliary tip] - v66:[updateContainedComponent]
[UpdateTracker:9779099] Update Tracker - [Pathway:212436] Generic Transcription Pathway - v66:[addHasEvent]
[UpdateTracker:9899449] Update Tracker - [Complex:5228604] botA HC:LC dimer:NTNHA:HA [extracellular region] - v66:[updateContainedComponent]
[UpdateTracker:9779004] Update Tracker - [Reaction:8948146] FUNDC1 is phosphorylated by ULK1 at Ser17 - v66:[addInput, addOutput]
[UpdateTracker:9899390] Update Tracker - [Complex:182104] Raf1 complex [cytosol] - v66:[modifyName]
[UpdateTracker:9899497] Update Tracker - [Complex:166062] MyD88:TIRAP:BTK:activated TLR2/4 [plasma membrane] - v66:[addName, updateContainedComponent]
[UpdateTracker:9899413] Update Tracker - [EntityWithAccessionedSequence:8862601] UBE2J2-1 [endoplasmic reticulum membrane] - v66:[add_removeReferenceEntity, modifyName]
[UpdateTracker:9899608] Update Tracker - [Complex:166100] IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane] - v66:[addName, updateContainedComponent]
[UpdateTracker:9899381] Update Tracker - [Complex:203870] Ran:GTP:Exportin-5 [nucleoplasm] - v66:[updateContainedComponent]
[UpdateTracker:9899439] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v66:[updateContainedMemberOrCandidate]
[UpdateTracker:9899477] Update Tracker - [EntityWithAccessionedSequence:190059] NGF [cytosol] - v66:[add_removeCompartment]
[UpdateTracker:9779078] Update Tracker - [Pathway:111932] CaMK IV-mediated phosphorylation of CREB - v66:[updateContainedRLE]
[UpdateTracker:9899434] Update Tracker - [Complex:190081] Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] - v66:[add_removeCompartment, add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9779053] Update Tracker - [Pathway:168188] Toll Like Receptor TLR6:TLR2 Cascade - v66:[updateIndirectRLE]
[UpdateTracker:9899424] Update Tracker - [EntityWithAccessionedSequence:199314] p-T32,S197,S262-FOXO4 [nucleoplasm] - v66:[add_removeReferenceEntity, modifyName]
[UpdateTracker:9779002] Update Tracker - [Pathway:71387] Metabolism of carbohydrates - v66:[addLiteratureReference, modifyText]
[UpdateTracker:9899563] Update Tracker - [DefinedSet:390445] unfolded actin/tubulin [cytosol] - v66:[add_removeHasMember]
[UpdateTracker:9779008] Update Tracker - [Pathway:187687] Signalling to ERKs - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9779227] Update Tracker - [Reaction:156682] PLK1 phosphorylates NUDC - v66:[addInput, addOutput]
[UpdateTracker:9778968] Update Tracker - [Pathway:74160] Gene expression (Transcription) - v66:[updateContainedPathway]
[UpdateTracker:9899524] Update Tracker - [Complex:2976708] NICD2:Rbpj:p-S133-Creb1:Ep300:Gzmb Gene [nucleoplasm] - v66:[add_removeHasComponent]
[UpdateTracker:9899435] Update Tracker - [Complex:2400008] PI3K Inhibitors:PI3K [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899383] Update Tracker - [Complex:390633] ADRA1A,B,D:ADR,NAd [plasma membrane] - v66:[modifyName]
[UpdateTracker:9779097] Update Tracker - [Pathway:190861] Gap junction assembly - v66:[updateContainedRLE]
[UpdateTracker:9899505] Update Tracker - [CandidateSet:8955715] alpha-tubulinY [cytosol] - v66:[add_removeHasCandidate]
[UpdateTracker:9779215] Update Tracker - [BlackBoxEvent:167121] Addition of the third nucleotide on the nascent HIV-1 transcript - v66:[removeCatalystActivity]
[UpdateTracker:9779166] Update Tracker - [Reaction:209310] Murine JAK2 binds to the Erythropoietin receptor, EpoR - v66:[addSummation]
[UpdateTracker:9899565] Update Tracker - [Complex:5228590] botA HC:LC dimer [extracellular region] - v66:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9899454] Update Tracker - [DefinedSet:391181] Ligand:GPCR complexes that activate Gs [plasma membrane] - v66:[addHasMember, updateContainedMemberOrCandidate]
[UpdateTracker:9899578] Update Tracker - [Complex:5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899442] Update Tracker - [Complex:5625417] anterograde IFT trains [ciliary tip] - v66:[updateContainedComponent]
[UpdateTracker:9899394] Update Tracker - [Complex:8982633] ADRB2:Catecholamine:GRK [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9899605] Update Tracker - [Complex:3928543] EFNBs:p-EPHBs:SFKs:Glu:NMDAR:Gly [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779195] Update Tracker - [Pathway:427413] NoRC negatively regulates rRNA expression - v66:[updateContainedRLE]
[UpdateTracker:9899432] Update Tracker - [Complex:2029135] Dynein:Dynactin:microtubule [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779245] Update Tracker - [Reaction:170979] (Frs2)C3G stimulates nucleotide exchange on Rap1 - v66:[addLiteratureReference, add_removeInput, add_removeOutput]
[UpdateTracker:9899600] Update Tracker - [DefinedSet:199933] p-MEF2 [nucleoplasm] - v66:[modifyName]
[UpdateTracker:9899521] Update Tracker - [Complex:749450] Ligand:GPCR complexes that activate Gz:Heterotrimeric G-protein Gz (inactive) [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779226] Update Tracker - [Reaction:209184] Rat JNK1 kinase transports from the cytosol to the nucleus - v66:[addSummation]
[UpdateTracker:9779022] Update Tracker - [Reaction:1253343] WWOX binds ERBB4s80 - v66:[addLiteratureReference, modifyText]
[UpdateTracker:9779171] Update Tracker - [Pathway:166058] MyD88:MAL(TIRAP) cascade initiated on plasma membrane - v66:[updateContainedRLE]
[UpdateTracker:9779229] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v66:[modifyText, updateContainedRLE]
[UpdateTracker:9779055] Update Tracker - [Pathway:167044] Signalling to RAS - v66:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9899567] Update Tracker - [Complex:190035] botA LC:Zn2+ [plasma membrane] - v66:[add_removeHasComponent]
[UpdateTracker:9778989] Update Tracker - [Pathway:211976] Endogenous sterols - v66:[updateIndirectRLE]
[UpdateTracker:9779115] Update Tracker - [Pathway:186797] Signaling by PDGF - v66:[updateIndirectRLE]
[UpdateTracker:9899416] Update Tracker - [Complex:180712] Rev:importin-beta:B23:Ran-GTP complex [nucleoplasm] - v66:[updateContainedComponent]
[UpdateTracker:9779248] Update Tracker - [Reaction:2976706] Notch2 and phosphorylated Creb1 bind Gzmb promoter - v66:[add_removeInput]
[UpdateTracker:9779019] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v66:[updateIndirectRLE]
[UpdateTracker:9899433] Update Tracker - [Complex:390446] CCT/TRiC:ATP:unfolded tubulin complex [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779154] Update Tracker - [Reaction:170977] FRS2 is phosphorylated by active TrkA receptor - v66:[add_removeCatalystActivity, add_removeInput, add_removeOutput]
[UpdateTracker:9899613] Update Tracker - [Complex:169877] p-S,T-BRAF complex [cytosol] - v66:[addHasComponent, modifyName]
[UpdateTracker:9779298] Update Tracker - [Pathway:2980736] Peptide hormone metabolism - v66:[updateIndirectRLE]
[UpdateTracker:9899545] Update Tracker - [Complex:165552] Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779199] Update Tracker - [Pathway:166016] Toll Like Receptor 4 (TLR4) Cascade - v66:[updateIndirectRLE]
[UpdateTracker:9899610] Update Tracker - [EntityWithAccessionedSequence:376244] AHCTF1 [cytosol] - v66:[modifyName]
[UpdateTracker:9899559] Update Tracker - [CandidateSet:202072] p-T,p-S-AKT [nucleoplasm] - v66:[addName]
[UpdateTracker:9899467] Update Tracker - [Complex:166118] p-IRAK1:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v66:[modifyName, updateContainedComponent]
[UpdateTracker:9899481] Update Tracker - [EntityWithAccessionedSequence:190064] p-5Y-NTRK1-1 [endosome membrane] - v66:[add_removeCompartment]
[UpdateTracker:9779057] Update Tracker - [Pathway:1632852] Macroautophagy - v66:[updateContainedRLE]
[UpdateTracker:9899572] Update Tracker - [Complex:937055] p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v66:[modifyName, updateContainedComponent]
[UpdateTracker:9899457] Update Tracker - [Complex:8867380] Polyglycyl alpha tubulin:GTP [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9778993] Update Tracker - [Pathway:8934903] Receptor Mediated Mitophagy - v66:[updateContainedRLE]
[UpdateTracker:9899436] Update Tracker - [Complex:379273] Mature centrosome:nucleated microtubules [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779095] Update Tracker - [Pathway:72662] Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S - v66:[updateContainedRLE]
[UpdateTracker:9899422] Update Tracker - [Complex:983686] p-BLNK:GRB2:SOS1:CIN85 [plasma membrane] - v66:[modifyName, removeHasComponent]
[UpdateTracker:9779165] Update Tracker - [Pathway:1168372] Downstream signaling events of B Cell Receptor (BCR) - v66:[updateIndirectRLE]
[UpdateTracker:9899536] Update Tracker - [Polymer:8982424] Microtubule protofilament [cytosol] - v66:[updateContainedRepeatedUnit]
[UpdateTracker:9899601] Update Tracker - [Complex:8955870] Alpha-polyglutamyl alpha-beta tubulin dimer [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779212] Update Tracker - [Pathway:629587] Highly sodium permeable postsynaptic acetylcholine nicotinic receptors - v66:[updateContainedRLE]
[UpdateTracker:9779135] Update Tracker - [Pathway:74713] IRS activation - v66:[modifyText]
[UpdateTracker:9899592] Update Tracker - [Complex:165537] Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP [nucleoplasm] - v66:[updateContainedComponent]
[UpdateTracker:9779179] Update Tracker - [Pathway:168179] Toll Like Receptor TLR1:TLR2 Cascade - v66:[updateIndirectRLE]
[UpdateTracker:9899465] Update Tracker - [EntityWithAccessionedSequence:182032] p-S,T-Raf1 [cytosol] - v66:[modifyName]
[UpdateTracker:9899464] Update Tracker - [Complex:169882] Rap1-GTP complex:p-S,T-BRAF complex [plasma membrane] - v66:[modifyName, updateContainedComponent]
[UpdateTracker:9899604] Update Tracker - [Complex:749447] Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779207] Update Tracker - [Reaction:167084] Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex - v66:[addInput, addOutput]
[UpdateTracker:9899541] Update Tracker - [Complex:1458522] GGC-RAB4A:GTP:KIF3:microtubule [cytoplasmic vesicle membrane] - v66:[updateContainedComponent]
[UpdateTracker:9899503] Update Tracker - [Complex:2976561] NOTCH2 coactivator complex:p-S133-CREB1:EP300:GZMB Gene [nucleoplasm] - v66:[add_removeHasComponent]
[UpdateTracker:9899414] Update Tracker - [Complex:391249] native alpha tubulin-GTP [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899485] Update Tracker - [DefinedSet:790204] GPCRs that activate Gs [plasma membrane] - v66:[add_removeHasMember]
[UpdateTracker:9779289] Update Tracker - [Pathway:73854] RNA Polymerase I Promoter Clearance - v66:[updateIndirectRLE]
[UpdateTracker:9899443] Update Tracker - [Complex:2468282] Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - v66:[updateContainedComponent]
[UpdateTracker:9779286] Update Tracker - [Pathway:449147] Signaling by Interleukins - v66:[updateIndirectRLE]
[UpdateTracker:9779246] Update Tracker - [Reaction:170978] p-FRS2:CRKL binds C3G - v66:[addLiteratureReference, add_removeInput, modifyText]
[UpdateTracker:9899448] Update Tracker - [Complex:190082] RAP1:GTP:B-Raf complex [endosome membrane] - v66:[add_removeCompartment, add_removeHasComponent, modifyName]
[UpdateTracker:9899492] Update Tracker - [Polymer:5624939] acetylated microtubule [axonemal microtubule] - v66:[updateContainedRepeatedUnit]
[UpdateTracker:9779284] Update Tracker - [Pathway:399721] Glutamate binding, activation of AMPA receptors and synaptic plasticity - v66:[updateIndirectRLE]
[UpdateTracker:9899469] Update Tracker - [Complex:983692] BLNK:GRB2:SOS1:CIN85 [cytosol] - v66:[modifyName, removeHasComponent]
[UpdateTracker:9779127] Update Tracker - [Pathway:442982] Ras activation upon Ca2+ influx through NMDA receptor - v66:[updateContainedRLE]
[UpdateTracker:9899531] Update Tracker - [Complex:5244411] botA HC:LC dimer:SV2:GT1b [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9899527] Update Tracker - [Complex:6808904] RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] - v66:[updateContainedComponent]
[UpdateTracker:9779037] Update Tracker - [Reaction:5577237] KCNH2:KCNE transport K+ from cytosol to extracellular region - v66:[addRegulator]
[UpdateTracker:9899606] Update Tracker - [Complex:2262774] TRAF6:p-IRAK2 :p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane] - v66:[modifyName, updateContainedComponent]
[UpdateTracker:9779182] Update Tracker - [Pathway:4090294] SUMOylation of intracellular receptors - v66:[updateContainedRLE]
[UpdateTracker:9779175] Update Tracker - [Pathway:159854] Gamma-carboxylation, transport, and amino-terminal cleavage of proteins - v66:[updateContainedPathway]
[UpdateTracker:9899540] Update Tracker - [Complex:5618327] acetylated microtubule [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779065] Update Tracker - [Pathway:392170] ADP signalling through P2Y purinoceptor 12 - v66:[updateContainedRLE]
[UpdateTracker:9779005] Update Tracker - [Pathway:5576891] Cardiac conduction - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9779191] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v66:[updateContainedRLE]
[UpdateTracker:9779000] Update Tracker - [Reaction:1500761] Nitrogen dioxide is reduced to NO by F420 - v66:[add_removeInput, add_removeOutput]
[UpdateTracker:9779013] Update Tracker - [Pathway:5576886] Phase 4 - resting membrane potential - v66:[updateContainedRLE]
[UpdateTracker:9778980] Update Tracker - [Pathway:170984] ARMS-mediated activation - v66:[addHasEvent, updateContainedRLE]
[UpdateTracker:9779017] Update Tracker - [Pathway:162582] Signal Transduction - v66:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9779292] Update Tracker - [Pathway:111931] PKA-mediated phosphorylation of CREB - v66:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9899440] Update Tracker - [Complex:8955574] detyr-alpha tubulin:beta tubulin [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9779153] Update Tracker - [Pathway:9006925] Intracellular signaling by second messengers - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9779056] Update Tracker - [Reaction:111912] CaMK4 phosphorylates CREB1 - v66:[addLiteratureReference, modifyText]
[UpdateTracker:9779232] Update Tracker - [Reaction:4551683] SUMOylation of TOPORS with SUMO1 - v66:[modifyText]
[UpdateTracker:9899461] Update Tracker - [Complex:442735] Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] - v66:[add_removeHasComponent]
[UpdateTracker:9778981] Update Tracker - [Pathway:167160] RNA Pol II CTD phosphorylation and interaction with CE during HIV infection - v66:[updateContainedRLE]
[UpdateTracker:9779167] Update Tracker - [Pathway:77387] Insulin receptor recycling - v66:[updateContainedRLE]
[UpdateTracker:9779027] Update Tracker - [Pathway:375276] Peptide ligand-binding receptors - v66:[addHasEvent, updateContainedRLE]
[UpdateTracker:9779294] Update Tracker - [Reaction:2730593] Phosphorylated Stat5 dimerizes - v66:[addLiteratureReference, modifyText]
[UpdateTracker:9899405] Update Tracker - [Complex:5618322] Ac K40 alpha tubulin-beta tubulin dimer [cytosol] - v66:[updateContainedComponent]
[UpdateTracker:9899486] Update Tracker - [Complex:190067] beta-NGF homodimer [cytosol] - v66:[add_removeCompartment]
[UpdateTracker:9899500] Update Tracker - [Complex:744890] GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] - v66:[updateContainedComponent]
[UpdateTracker:9779196] Update Tracker - [Pathway:629597] Highly calcium permeable nicotinic acetylcholine receptors - v66:[updateContainedRLE]
[UpdateTracker:9779138] Update Tracker - [Reaction:170975] p-FRS2 binds CRKL - v66:[addLiteratureReference, add_removeInput]
[UpdateTracker:9899496] Update Tracker - [Complex:937048] p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane] - v66:[modifyName, updateContainedComponent]
[UpdateTracker:9779273] Update Tracker - [Pathway:112316] Neuronal System - v66:[updateContainedPathway]
[UpdateTracker:9779107] Update Tracker - [Pathway:2022377] Metabolism of Angiotensinogen to Angiotensins - v66:[updateContainedRLE]
[UpdateTracker:9899510] Update Tracker - [Complex:190068] Active TrkA receptor:FRS2 complex [endosome membrane] - v66:[add_removeCompartment, add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9779277] Update Tracker - [Reaction:187661] Ade-Rib binds AODORA2A and NTRK1,2 - v66:[modifyText, removeCatalystActivity, removeOutput]
[UpdateTracker:9779139] Update Tracker - [Reaction:5672010] Active MTORC1 phosphorylates ULK1 - v66:[addInput, addOutput]
[UpdateTracker:9779187] Update Tracker - [Pathway:77075] RNA Pol II CTD phosphorylation and interaction with CE - v66:[updateContainedRLE]
[UpdateTracker:9779200] Update Tracker - [Reaction:374173] AGT(34-41) binds to AGTR1 - v66:[addRegulator, add_removeInput, removeLiteratureReference]
[UpdateTracker:9899532] Update Tracker - [Complex:507919] p-STAT5 dimer [cytosol] - v66:[add_removeHasComponent]
[UpdateTracker:9779077] Update Tracker - [Pathway:622327] Postsynaptic nicotinic acetylcholine receptors - v66:[updateIndirectRLE]
[UpdateTracker:9899611] Update Tracker - [Complex:2484819] Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - v66:[updateContainedComponent]
[UpdateTracker:9779205] Update Tracker - [Reaction:209104] Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex - v66:[addSummation]
[UpdateTracker:9779024] Update Tracker - [Pathway:1280218] Adaptive Immune System - v66:[updateContainedPathway]
[UpdateTracker:9899519] Update Tracker - [Complex:169874] Rap1-GTP complex [plasma membrane] - v66:[modifyName]
[UpdateTracker:9779007] Update Tracker - [Pathway:199977] ER to Golgi Anterograde Transport - v66:[updateIndirectRLE]
[UpdateTracker:9779040] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v66:[updateContainedPathway]
[UpdateTracker:9899476] Update Tracker - [Complex:5624919] Ac K40 alpha tubulin:GTP [axonemal microtubule] - v66:[updateContainedComponent]
[UpdateTracker:9779025] Update Tracker - [Pathway:74749] Signal attenuation - v66:[updateContainedRLE]

Cite Us!