Reactome | 68 on 2019-03-25

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68 on 2019-03-25 Show undefined attributes

dbId	9777828
displayName	68 on 2019-03-25
modified	[InstanceEdit:9982963] Weiser, Joel, 2026-02-20
releaseDate	2019-03-25
releaseNumber	68
schemaClass	Release

Referrals

(release)

[UpdateTracker:9900170] Update Tracker - [DefinedSet:8869156] AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778514] Update Tracker - [Pathway:975871] MyD88 cascade initiated on plasma membrane - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778254] Update Tracker - [FailedReaction:5659998] Defective TALDO1 does not transform Fru(6)P, E4P to SH7P, GA3P - v68:[addCatalystActivity]
[UpdateTracker:9900123] Update Tracker - [CandidateSet:921124] RGS proteins active for G alpha (i) [plasma membrane] - v68:[removeCompartment]
[UpdateTracker:9778346] Update Tracker - [FailedReaction:5679101] Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region - v68:[addCatalystActivity]
[UpdateTracker:9900072] Update Tracker - [EntityWithAccessionedSequence:2466850] ABCA4 A1028V [photoreceptor disc membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900322] Update Tracker - [SimpleEntity:5228361] GD3 [endocytic vesicle membrane] - v68:[addName]
[UpdateTracker:9900180] Update Tracker - [SimpleEntity:5228380] GD3 [clathrin-coated endocytic vesicle membrane] - v68:[addName]
[UpdateTracker:9778669] Update Tracker - [Pathway:5579006] Defective GSS causes GSS deficiency - v68:[updateContainedRLE]
[UpdateTracker:9778331] Update Tracker - [Pathway:70268] Pyruvate metabolism - v68:[updateIndirectRLE]
[UpdateTracker:9778239] Update Tracker - [FailedReaction:3315483] Phosphorylated SMAD2/3 MH2 Domain Mutants do not bind SMAD4 - v68:[modifyText]
[UpdateTracker:9900307] Update Tracker - [Complex:70218] PGM1:Mg2+ [cytosol] - v68:[modifyName]
[UpdateTracker:9900050] Update Tracker - [Complex:9021654] ESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] - v68:[modifyName, updateContainedComponent]
[UpdateTracker:9778506] Update Tracker - [Pathway:74160] Gene expression (Transcription) - v68:[updateContainedPathway]
[UpdateTracker:9778663] Update Tracker - [Pathway:109581] Apoptosis - v68:[updateContainedPathway]
[UpdateTracker:9778646] Update Tracker - [Pathway:1474165] Reproduction - v68:[updateContainedPathway]
[UpdateTracker:9778320] Update Tracker - [Pathway:5653656] Vesicle-mediated transport - v68:[updateContainedPathway]
[UpdateTracker:9778300] Update Tracker - [Pathway:2206280] MPS IX - Natowicz syndrome - v68:[updateContainedRLE]
[UpdateTracker:9778344] Update Tracker - [Pathway:5579021] Defective CYP21A2 causes AH3 - v68:[updateContainedRLE]
[UpdateTracker:9778185] Update Tracker - [Reaction:8952419] SMURFs ubiquitinate RUNX3 - v68:[add_removeInput]
[UpdateTracker:9778323] Update Tracker - [Pathway:5083627] Defective LARGE causes MDDGA6 and MDDGB6 - v68:[updateContainedRLE]
[UpdateTracker:9778612] Update Tracker - [Pathway:5579000] Defective CYP1B1 causes Glaucoma - v68:[updateContainedRLE]
[UpdateTracker:9778458] Update Tracker - [Pathway:3296469] Defects in cobalamin (B12) metabolism - v68:[updateIndirectRLE]
[UpdateTracker:9900319] Update Tracker - [Polymer:8939707] polyubiquitin chain [nucleoplasm] - v68:[add_removeRepeatedUnit]
[UpdateTracker:9778444] Update Tracker - [FailedReaction:5683355] Defective ABCB6 does not transport porphyrin from cytosol into mitochondria matrix - v68:[addCatalystActivity]
[UpdateTracker:9778084] Update Tracker - [Pathway:75153] Apoptotic execution phase - v68:[updateContainedPathway]
[UpdateTracker:9900048] Update Tracker - [EntityWithAccessionedSequence:8869086] EGF [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900203] Update Tracker - [EntityWithAccessionedSequence:5688002] SFTPB P121Efs*95 [endoplasmic reticulum membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777827] Update Tracker - [Pathway:1810476] RIP-mediated NFkB activation via ZBP1 - v68:[updateContainedRLE]
[UpdateTracker:9778119] Update Tracker - [Pathway:5678420] Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome - v68:[updateContainedRLE]
[UpdateTracker:9777841] Update Tracker - [FailedReaction:9036077] Defective HYAL1 does not hydrolyse (HA)50 - v68:[addCatalystActivity]
[UpdateTracker:9778063] Update Tracker - [FailedReaction:3781832] Defective MPI does not isomerize Fru6P to Man6P - v68:[addCatalystActivity]
[UpdateTracker:9777998] Update Tracker - [Pathway:168928] DDX58/IFIH1-mediated induction of interferon-alpha/beta - v68:[updateIndirectRLE]
[UpdateTracker:9777985] Update Tracker - [FailedReaction:2263496] Defective NAGLU does not hydrolyse Heparan sulfate chain(4) - v68:[addCatalystActivity]
[UpdateTracker:9778315] Update Tracker - [FailedReaction:5623806] Defective SLC12A6 does not cotransport K+, Cl- from cytosol to extracellular region - v68:[addCatalystActivity]
[UpdateTracker:9900154] Update Tracker - [Complex:350052] RBPJ:NCOR corepressor complex [nucleoplasm] - v68:[add_removeHasComponent]
[UpdateTracker:9900141] Update Tracker - [Complex:5637693] p-5Y-EGFRvIII:GRB2:GAB1:PI3K [plasma membrane] - v68:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9777967] Update Tracker - [Pathway:5619054] Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) - v68:[updateContainedRLE]
[UpdateTracker:9778478] Update Tracker - [Pathway:3595174] Defective CHST14 causes EDS, musculocontractural type - v68:[updateContainedRLE]
[UpdateTracker:9778678] Update Tracker - [Pathway:573298] NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation - v68:[updateContainedPathway]
[UpdateTracker:9778108] Update Tracker - [FailedReaction:9036068] Defective GUSB does not hydrolyse GlcA-?1,3-GlcNAc - v68:[addCatalystActivity]
[UpdateTracker:9900197] Update Tracker - [SimpleEntity:389631] Fe2+ [peroxisomal matrix] - v68:[add_removeReferenceEntity, removeName]
[UpdateTracker:9900191] Update Tracker - [EntityWithAccessionedSequence:2685607] p-T1400,T1412-MAP3K1 [cytosol] - v68:[modifyName]
[UpdateTracker:9778552] Update Tracker - [Pathway:597592] Post-translational protein modification - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9777915] Update Tracker - [Pathway:5083632] Defective C1GALT1C1 causes TNPS - v68:[updateContainedRLE]
[UpdateTracker:9778261] Update Tracker - [Pathway:4793953] Defective B4GALT1 causes CDG-2d - v68:[updateContainedRLE]
[UpdateTracker:9778510] Update Tracker - [FailedReaction:5602170] CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol - v68:[addCatalystActivity]
[UpdateTracker:9778016] Update Tracker - [FailedReaction:2263495] Defective GNS does not hydrolyse 6-sulfate from GlcNAc6S - v68:[addCatalystActivity]
[UpdateTracker:9900164] Update Tracker - [EntityWithAccessionedSequence:2471954] RBP4 I41N [extracellular region] - v68:[add_removeCompartment]
[UpdateTracker:9778177] Update Tracker - [FailedReaction:5656248] Defective SLC4A1 does not exchange Cl- for HCO3- (in erythrocytes) - v68:[addCatalystActivity]
[UpdateTracker:9777859] Update Tracker - [Pathway:3322077] Glycogen synthesis - v68:[addHasEvent]
[UpdateTracker:9778212] Update Tracker - [FailedReaction:2282889] Defective ARSB does not hydrolyse C4S/C6S chains - v68:[addCatalystActivity]
[UpdateTracker:9900232] Update Tracker - [Complex:5228828] NFKBIA variants:NFkB complex [cytosol] - v68:[addName, updateContainedComponent]
[UpdateTracker:9900163] Update Tracker - [Complex:6783450] tRNA:XPOT:RAN:GTP [nucleoplasm] - v68:[updateContainedComponent]
[UpdateTracker:9778011] Update Tracker - [Pathway:5619036] Defective SLC24A5 causes oculocutaneous albinism 6 (OCA6) - v68:[updateContainedRLE]
[UpdateTracker:9900042] Update Tracker - [EntityWithAccessionedSequence:8871126] GGC-RAB5B [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778313] Update Tracker - [Pathway:5684045] Defective ABCD1 causes ALD - v68:[updateContainedRLE]
[UpdateTracker:9778270] Update Tracker - [Pathway:3785653] Myoclonic epilepsy of Lafora - v68:[updateContainedRLE]
[UpdateTracker:9778138] Update Tracker - [Pathway:5579020] Defective SLC35D1 causes SCHBCKD - v68:[updateContainedRLE]
[UpdateTracker:9778479] Update Tracker - [FailedReaction:6785244] Defective CYP11B2 does not oxidise 18HCORST - v68:[addCatalystActivity]
[UpdateTracker:9777973] Update Tracker - [FailedReaction:2263492] Defective HGSNAT does not acetylate Heparan chain(1) - v68:[addCatalystActivity]
[UpdateTracker:9778058] Update Tracker - [FailedReaction:4755600] Defective DOLK does not phosphorylate DCHOL - v68:[addCatalystActivity]
[UpdateTracker:9778463] Update Tracker - [FailedReaction:9035987] Defective HLCS does not biotinylate 6xMCCC1:6xMCCC2 - v68:[addCatalystActivity]
[UpdateTracker:9778110] Update Tracker - [Reaction:975340] GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol - v68:[addLiteratureReference]
[UpdateTracker:9778474] Update Tracker - [FailedReaction:5678822] Defective CFTR does not transport Cl- from cytosol to extracellular region - v68:[addCatalystActivity]
[UpdateTracker:9778255] Update Tracker - [FailedReaction:3656230] Defective B4GALT1 does not transfer Gal to the keratan chain - v68:[addCatalystActivity]
[UpdateTracker:9900311] Update Tracker - [Complex:5694290] MIA2:PREB [endoplasmic reticulum membrane] - v68:[add_removeHasComponent, modifyName]
[UpdateTracker:9778404] Update Tracker - [Pathway:418555] G alpha (s) signalling events - v68:[addHasEvent, updateContainedRLE]
[UpdateTracker:9778433] Update Tracker - [FailedReaction:4720478] Defective ALG9 does not add the seventh mannose to the N-glycan precursor - v68:[addCatalystActivity]
[UpdateTracker:9900103] Update Tracker - [SimpleEntity:1222286] Fe2+ [phagocytic vesicle lumen] - v68:[add_removeReferenceEntity, removeName]
[UpdateTracker:9778007] Update Tracker - [FailedReaction:4549368] Defective ALG2 does not transfer a second Man to N-glycan precursor - v68:[addCatalystActivity]
[UpdateTracker:9778172] Update Tracker - [Pathway:5655799] Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) - v68:[updateContainedRLE]
[UpdateTracker:9778381] Update Tracker - [Pathway:5619067] Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA) - v68:[updateContainedRLE]
[UpdateTracker:9778619] Update Tracker - [Pathway:5619113] Defective SLC3A1 causes cystinuria (CSNU) - v68:[updateContainedRLE]
[UpdateTracker:9778526] Update Tracker - [Pathway:350431] Planar Cell Polarity pathway - v68:[updateContainedPathway]
[UpdateTracker:9778371] Update Tracker - [Pathway:5619070] Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) - v68:[updateContainedRLE]
[UpdateTracker:9778277] Update Tracker - [Reaction:8875183] CBL monoubiquitinates activated MET - v68:[add_removeInput]
[UpdateTracker:9900094] Update Tracker - [DefinedSet:8869164] ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedMemberOrCandidate]
[UpdateTracker:9778041] Update Tracker - [FailedReaction:9036021] Defective MPDU1 does not promote transfer of Man to (GlcNAc)2 (Man)6 (PP-Dol)1 by ALG9 - v68:[addRegulator]
[UpdateTracker:9778333] Update Tracker - [Pathway:372708] p130Cas linkage to MAPK signaling for integrins - v68:[updateContainedRLE]
[UpdateTracker:9900276] Update Tracker - [Complex:1605684] NEU1:GLB1:CTSA dimer [lysosomal lumen] - v68:[modifyName]
[UpdateTracker:9778475] Update Tracker - [Pathway:5619107] Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) - v68:[updateContainedRLE]
[UpdateTracker:9900213] Update Tracker - [Complex:8871141] GGC-RAB5:GTP [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9778099] Update Tracker - [Pathway:425397] Transport of vitamins, nucleosides, and related molecules - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778674] Update Tracker - [FailedReaction:9035950] Defective B4GALT1 does not transfer Gal to a branch of keratan - v68:[addCatalystActivity]
[UpdateTracker:9900356] Update Tracker - [EntityWithAccessionedSequence:159765] 3OHD110-F9(29-461) [endoplasmic reticulum lumen] - v68:[modifyName]
[UpdateTracker:9900131] Update Tracker - [Complex:606328] CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA nucleosome [nucleoplasm] - v68:[modifyName]
[UpdateTracker:9778611] Update Tracker - [FailedReaction:5603275] Defective TBXAS1 does not isomerise PGH2 to TXA2 - v68:[addCatalystActivity]
[UpdateTracker:9777907] Update Tracker - [FailedReaction:5682311] Defective ABCA12 does not transport lipids from cytosol to extracellular region - v68:[addCatalystActivity]
[UpdateTracker:9778621] Update Tracker - [FailedReaction:5624239] Defective SLC17A5 does not cotransport Neu5Ac, H+ from lysosomal lumen to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778107] Update Tracker - [Pathway:5357609] Glycogen storage disease type II (GAA) - v68:[updateContainedRLE]
[UpdateTracker:9778289] Update Tracker - [Pathway:110330] Recognition and association of DNA glycosylase with site containing an affected purine - v68:[addHasEvent]
[UpdateTracker:9777843] Update Tracker - [Pathway:5619095] Defective SLCO2A1 causes primary, autosomal recessive hypertrophic osteoarthropathy 2 (PHOAR2) - v68:[updateContainedRLE]
[UpdateTracker:9778081] Update Tracker - [Pathway:997272] Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits - v68:[addHasEvent]
[UpdateTracker:9778203] Update Tracker - [Pathway:3560801] Defective B3GAT3 causes JDSSDHD - v68:[updateContainedRLE]
[UpdateTracker:9778536] Update Tracker - [Reaction:448678] CTSG cleaves CASP1(1-404) - v68:[addCatalystActivity]
[UpdateTracker:9778519] Update Tracker - [Pathway:446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein - v68:[updateContainedPathway]
[UpdateTracker:9778459] Update Tracker - [FailedReaction:5638209] Defective SLC2A9 does not transport Fru, Glc, urate - v68:[addCatalystActivity]
[UpdateTracker:9778496] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v68:[updateContainedRLE]
[UpdateTracker:9777936] Update Tracker - [FailedReaction:5659734] Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778296] Update Tracker - [FailedReaction:5661184] Defective SLCO1B1 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte) - v68:[addCatalystActivity]
[UpdateTracker:9778375] Update Tracker - [Pathway:5690338] Defective ABCC6 causes PXE - v68:[updateContainedRLE]
[UpdateTracker:9900045] Update Tracker - [Complex:8869160] KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778542] Update Tracker - [Reaction:5694427] MIA3 binds procollagen VII - v68:[modifyText]
[UpdateTracker:9900171] Update Tracker - [EntityWithAccessionedSequence:8869121] SYT9 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900150] Update Tracker - [Complex:8854335] RAB35:GTP [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900219] Update Tracker - [Complex:8868627] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9900144] Update Tracker - [EntityWithAccessionedSequence:8869075] AVP(20-28) [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900320] Update Tracker - [SimpleEntity:5250590] GD2 [plasma membrane] - v68:[addName]
[UpdateTracker:9778666] Update Tracker - [FailedReaction:2262743] Defective IDS does not hydrolyse dermatan sulfate (Chebi:63517 chain) - v68:[addCatalystActivity]
[UpdateTracker:9900343] Update Tracker - [Complex:8869200] EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9900152] Update Tracker - [EntityWithAccessionedSequence:9628817] TGFA(24-98) [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778443] Update Tracker - [Pathway:5576891] Cardiac conduction - v68:[updateIndirectRLE]
[UpdateTracker:9778596] Update Tracker - [Reaction:6807106] PTEN undergoes monoubiquitination - v68:[add_removeInput]
[UpdateTracker:9778685] Update Tracker - [FailedReaction:5653596] Defective SLC35C1 does not transport UDP-Fuc from cytosol to Golgi lumen - v68:[addCatalystActivity]
[UpdateTracker:9778471] Update Tracker - [FailedReaction:5602063] Defective CYP26B1 does not 4-hydroxylate atRA - v68:[addCatalystActivity]
[UpdateTracker:9778347] Update Tracker - [Pathway:937061] TRIF(TICAM1)-mediated TLR4 signaling - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9777845] Update Tracker - [Pathway:5683329] Defective ABCD4 causes MAHCJ - v68:[updateContainedRLE]
[UpdateTracker:9778295] Update Tracker - [Pathway:434316] Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion - v68:[addLiteratureReference]
[UpdateTracker:9900231] Update Tracker - [Complex:180720] nucleoporin-associated Rev:Importin-beta:B23 complex [nuclear envelope] - v68:[updateContainedComponent]
[UpdateTracker:9778192] Update Tracker - [Pathway:4724325] Defective ALG8 causes CDG-1h - v68:[updateContainedRLE]
[UpdateTracker:9778045] Update Tracker - [Pathway:4755579] Defective SRD5A3 causes SRD5A3-CDG, KHRZ - v68:[updateContainedRLE]
[UpdateTracker:9900212] Update Tracker - [Complex:8935905] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9778024] Update Tracker - [FailedReaction:2466832] Defective RDH5 does not oxidise 11cROL to 11cRAL and causes RPA - v68:[addCatalystActivity]
[UpdateTracker:9778262] Update Tracker - [Pathway:5252538] Drosophila signaling pathways - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778106] Update Tracker - [FailedReaction:4085027] Defective GFPT1 does not transfer an amino group from L-Gln to F6P to form GlcN6P - v68:[addCatalystActivity]
[UpdateTracker:9778466] Update Tracker - [Pathway:4085001] Sialic acid metabolism - v68:[addHasEvent, updateContainedRLE]
[UpdateTracker:9777881] Update Tracker - [Pathway:4549356] Defective DPAGT1 causes CDG-1j, CMSTA2 - v68:[updateContainedRLE]
[UpdateTracker:9778524] Update Tracker - [FailedReaction:5659879] Defective SI does not hydrolyze iMal - v68:[addCatalystActivity]
[UpdateTracker:9900064] Update Tracker - [Complex:9027420] Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:Plcg1,2 [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9900333] Update Tracker - [DefinedSet:2316432] Activator:PI3K [plasma membrane] - v68:[updateContainedMemberOrCandidate]
[UpdateTracker:9778372] Update Tracker - [Pathway:69275] G2/M Transition - v68:[updateIndirectRLE]
[UpdateTracker:9778075] Update Tracker - [Pathway:9006931] Signaling by Nuclear Receptors - v68:[modifyText, updateContainedPathway]
[UpdateTracker:9778256] Update Tracker - [Pathway:975138] TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9777879] Update Tracker - [Pathway:9006936] Signaling by TGFB family members - v68:[updateIndirectRLE]
[UpdateTracker:9777833] Update Tracker - [Pathway:5579009] Defective CYP11B2 causes CMO-1 deficiency - v68:[updateContainedRLE]
[UpdateTracker:9778010] Update Tracker - [Reaction:5577213] LTCC multimer transports Ca2+ from extracellular region to cytosol - v68:[addRegulator]
[UpdateTracker:9900354] Update Tracker - [CandidateSet:8869175] ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedMemberOrCandidate]
[UpdateTracker:9778566] Update Tracker - [Reaction:177945] SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) - v68:[modifyText]
[UpdateTracker:9777878] Update Tracker - [Pathway:3656532] TGFBR1 KD Mutants in Cancer - v68:[removeHasEvent, updateContainedRLE]
[UpdateTracker:9900160] Update Tracker - [Complex:168155] NFKB1(1-433), NFKB2(1-454):RELA [cytosol] - v68:[modifyName, updateContainedComponent]
[UpdateTracker:9778618] Update Tracker - [Pathway:5619058] Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR) - v68:[updateContainedRLE]
[UpdateTracker:9777901] Update Tracker - [FailedReaction:5604975] Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BIL - v68:[addCatalystActivity]
[UpdateTracker:9778267] Update Tracker - [Pathway:3229121] Glycogen storage diseases - v68:[updateIndirectRLE]
[UpdateTracker:9900269] Update Tracker - [Complex:2033049] IgD Heavy Chain [plasma membrane] - v68:[add_removeHasComponent]
[UpdateTracker:9777912] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v68:[updateContainedRLE]
[UpdateTracker:9778004] Update Tracker - [Pathway:450736] Activation of Downstream Effectors - v68:[add_removeHasEvent, updateContainedPathway]
[UpdateTracker:9778335] Update Tracker - [FailedReaction:5625574] Defective SLC22A18 does not exchange extracellular organic cations for cytosolic H+ - v68:[addCatalystActivity]
[UpdateTracker:9778631] Update Tracker - [FailedReaction:6785668] Defective LARGE does not transfer Xyl from UDP-Xyl to GlcA - v68:[addCatalystActivity]
[UpdateTracker:9778402] Update Tracker - [Pathway:6791465] Pentose phosphate pathway disease - v68:[updateIndirectRLE]
[UpdateTracker:9778664] Update Tracker - [Pathway:8948751] Regulation of PTEN stability and activity - v68:[updateContainedRLE]
[UpdateTracker:9778307] Update Tracker - [FailedReaction:5660013] Defective RPIA does not isomerize RU5P to R5P - v68:[addCatalystActivity]
[UpdateTracker:9777962] Update Tracker - [Reaction:392051] Recruitment of Grb2 to pFAK:NCAM1 - v68:[modifyText]
[UpdateTracker:9900127] Update Tracker - [DefinedSet:168143] NFkB inhibitor [cytosol] - v68:[addName]
[UpdateTracker:9777979] Update Tracker - [Pathway:199977] ER to Golgi Anterograde Transport - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778091] Update Tracker - [Pathway:5578996] Defective CYP27A1 causes CTX - v68:[updateContainedRLE]
[UpdateTracker:9777899] Update Tracker - [FailedReaction:3560802] Defective B3GAT3 does not transfer GlcA to tetrasaccharide linker - v68:[addCatalystActivity]
[UpdateTracker:9778430] Update Tracker - [Reaction:109534] Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 - v68:[add_removeInput, add_removeOutput]
[UpdateTracker:9777922] Update Tracker - [FailedReaction:3595175] Defective CHST3 does not transfer SO4(2-) to chondroitin - v68:[addCatalystActivity]
[UpdateTracker:9777964] Update Tracker - [Pathway:168898] Toll-like Receptor Cascades - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9900222] Update Tracker - [SimpleEntity:435347] Fe2+ [extracellular region] - v68:[add_removeReferenceEntity, removeName]
[UpdateTracker:9900195] Update Tracker - [Complex:8876247] InlB:p-4Y-MET dimer:GRB2-1:p-Y-CBL [plasma membrane] - v68:[add_removeEntityOnOtherCell, removeCompartment, updateContainedComponent]
[UpdateTracker:9777902] Update Tracker - [Pathway:4687000] Defective MPDU1 causes CDG-1f - v68:[updateContainedRLE]
[UpdateTracker:9900227] Update Tracker - [Complex:9614184] GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9900043] Update Tracker - [SimpleEntity:879615] AA [extracellular region] - v68:[addName]
[UpdateTracker:9778533] Update Tracker - [Pathway:5619097] Defective SLC34A3 causes Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) - v68:[updateContainedRLE]
[UpdateTracker:9778249] Update Tracker - [Pathway:445989] TAK1-dependent IKK and NF-kappa-B activation - v68:[addHasEvent, updateContainedRLE]
[UpdateTracker:9900069] Update Tracker - [Complex:8943018] SHPRH:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] - v68:[updateContainedComponent]
[UpdateTracker:9778432] Update Tracker - [FailedReaction:9035514] Defective ALG9 does not add the last mannose to the N-glycan precursor - v68:[addCatalystActivity]
[UpdateTracker:9900129] Update Tracker - [Complex:8876254] InlB:MonoUb-K,p-4Y-MET [plasma membrane] - v68:[add_removeEntityOnOtherCell, add_removeHasComponent, removeCompartment]
[UpdateTracker:9777943] Update Tracker - [FailedReaction:4549382] Defective ALG1 does not transfer the first Man to the N-glycan precursor - v68:[addCatalystActivity]
[UpdateTracker:9778582] Update Tracker - [Pathway:3656225] Defective CHST6 causes MCDC1 - v68:[updateContainedRLE]
[UpdateTracker:9777829] Update Tracker - [Pathway:2206290] MPS IV - Morquio syndrome A - v68:[updateContainedRLE]
[UpdateTracker:9778420] Update Tracker - [Pathway:76002] Platelet activation, signaling and aggregation - v68:[updateIndirectRLE]
[UpdateTracker:9778462] Update Tracker - [Pathway:5619111] Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) - v68:[updateContainedRLE]
[UpdateTracker:9900062] Update Tracker - [DefinedSet:177656] NFKB1(1-433), NFKB2(1-454) [cytosol] - v68:[modifyName]
[UpdateTracker:9777960] Update Tracker - [Pathway:5619046] Defective SLC26A4 causes Pendred syndrome (PDS) - v68:[updateContainedRLE]
[UpdateTracker:9900221] Update Tracker - [EntityWithAccessionedSequence:8869129] VAMP2 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778396] Update Tracker - [Pathway:2206285] MPS VI - Maroteaux-Lamy syndrome - v68:[updateContainedRLE]
[UpdateTracker:9778500] Update Tracker - [Pathway:432626] Circadian Clock pathway - v68:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9777966] Update Tracker - [Reaction:5637765] Binding of PI3K to complex of GRB2:GAB1 and p-EGFRvIII - v68:[add_removeInput, modifyText]
[UpdateTracker:9778145] Update Tracker - [Reaction:437189] PDK1 binds PKC zeta - v68:[modifyText]
[UpdateTracker:9777880] Update Tracker - [Pathway:5579007] Defective ACY1 causes encephalopathy - v68:[updateContainedRLE]
[UpdateTracker:9778392] Update Tracker - [Pathway:3274531] Glycogen storage disease type Ia (G6PC) - v68:[updateContainedRLE]
[UpdateTracker:9900089] Update Tracker - [EntityWithAccessionedSequence:8869124] TFRC(1-760) [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778070] Update Tracker - [FailedReaction:5661474] Defective NPC does not transport GCK1:GKRP from cytosol to nucleoplasm - v68:[addCatalystActivity]
[UpdateTracker:9778158] Update Tracker - [FailedReaction:5625841] Defective SLC24A1 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ - v68:[addCatalystActivity]
[UpdateTracker:9777952] Update Tracker - [Pathway:5579011] Defective CYP2U1 causes SPG56 - v68:[updateContainedRLE]
[UpdateTracker:9900080] Update Tracker - [Complex:6803105] DCD hexamer:Zn(2+):anionic phospholipids [extracellular region] - v68:[updateContainedComponent]
[UpdateTracker:9778266] Update Tracker - [Pathway:5387390] Hh mutants abrogate ligand secretion - v68:[updateIndirectRLE]
[UpdateTracker:9778122] Update Tracker - [FailedReaction:5610026] Defective GALK1 does not phosphorylate Gal - v68:[addCatalystActivity]
[UpdateTracker:9778484] Update Tracker - [Pathway:5619055] Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI) - v68:[updateContainedRLE]
[UpdateTracker:9900109] Update Tracker - [SimpleEntity:111793] Fe2+ [nucleoplasm] - v68:[add_removeReferenceEntity, removeName]
[UpdateTracker:9778565] Update Tracker - [Pathway:353357] Base Excision Repair - v68:[updateContainedPathway]
[UpdateTracker:9778488] Update Tracker - [Pathway:140342] Apoptosis induced DNA fragmentation - v68:[addLiteratureReference, add_removeHasEvent, modifyText]
[UpdateTracker:9778008] Update Tracker - [Pathway:5619037] Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) - v68:[updateContainedRLE]
[UpdateTracker:9777938] Update Tracker - [FailedReaction:5627737] SLC26A3 does not exchange Cl- for HCO3- - v68:[addCatalystActivity]
[UpdateTracker:9778052] Update Tracker - [Pathway:69242] S Phase - v68:[updateContainedPathway]
[UpdateTracker:9778378] Update Tracker - [Pathway:73894] DNA Repair - v68:[updateContainedPathway]
[UpdateTracker:9900112] Update Tracker - [Complex:5694288] procollagen VII:MIA3:MIA2:PREB:SEC23A:SEC24C [endoplasmic reticulum membrane] - v68:[modifyName, updateContainedComponent]
[UpdateTracker:9778273] Update Tracker - [FailedReaction:4088322] Defective GNE does not phosphorylate ManNAc to ManNAc-6-P - v68:[addCatalystActivity]
[UpdateTracker:9778568] Update Tracker - [FailedReaction:5604954] Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BIL - v68:[addCatalystActivity]
[UpdateTracker:9778150] Update Tracker - [FailedReaction:5096532] Defective GALNT12 does not transfer GalNAc to mucins - v68:[addCatalystActivity]
[UpdateTracker:9778198] Update Tracker - [FailedReaction:5651942] Defective SLC35A1 does not exchange CMP-Neu5Ac for CMP - v68:[addCatalystActivity]
[UpdateTracker:9777914] Update Tracker - [Pathway:5619062] Defective SLC1A3 causes episodic ataxia 6 (EA6) - v68:[updateContainedRLE]
[UpdateTracker:9778094] Update Tracker - [Pathway:5579015] Defective CYP26B1 causes RHFCA - v68:[updateContainedRLE]
[UpdateTracker:9778573] Update Tracker - [Pathway:5579014] Defective CYP27B1 causes VDDR1A - v68:[updateContainedRLE]
[UpdateTracker:9777873] Update Tracker - [Pathway:3371598] Defective BTD causes biotidinase deficiency - v68:[updateContainedRLE]
[UpdateTracker:9900117] Update Tracker - [EntityWithAccessionedSequence:8871129] GGC-RAB5C [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778123] Update Tracker - [FailedReaction:2263444] Defective SGSH does not hydrolyse Heparan sulfate chain(7) - v68:[addCatalystActivity]
[UpdateTracker:9900162] Update Tracker - [Complex:8942129] Ub:UBE2A,B [nucleoplasm] - v68:[add_removeHasComponent]
[UpdateTracker:9900255] Update Tracker - [Complex:8876941] InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1:CTNND1 [plasma membrane] - v68:[removeCompartment]
[UpdateTracker:9777871] Update Tracker - [Pathway:5578999] Defective GCLC causes HAGGSD - v68:[updateContainedRLE]
[UpdateTracker:9778279] Update Tracker - [BlackBoxEvent:480520] Expression of SALL4 - v68:[removeCatalystActivity]
[UpdateTracker:9900184] Update Tracker - [EntityWithAccessionedSequence:8869116] SYT2 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778360] Update Tracker - [BlackBoxEvent:8939801] 26S proteasome degrades PolyUb-RUNX2 - v68:[add_removeOutput]
[UpdateTracker:9900199] Update Tracker - [EntityWithAccessionedSequence:8869137] VAMP8 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778324] Update Tracker - [Pathway:6791055] TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P - v68:[updateContainedRLE]
[UpdateTracker:9900285] Update Tracker - [Complex:213135] Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778257] Update Tracker - [FailedReaction:5602606] Defective MyD88 does not bind MAL(TIRAP):TLR2/4 - v68:[add_removeInput]
[UpdateTracker:9778252] Update Tracker - [Reaction:1226016] Binding of GRB2:GAB1 complex to ligand-responsive p-6Y-EGFR mutants - v68:[add_removeInput, modifyText]
[UpdateTracker:9900147] Update Tracker - [EntityWithAccessionedSequence:8942439] RIOX2 [nucleoplasm] - v68:[modifyName]
[UpdateTracker:9777955] Update Tracker - [FailedReaction:5600598] Defective CYP11B2 does not oxidise 11DCORST - v68:[addCatalystActivity]
[UpdateTracker:9900200] Update Tracker - [Complex:354103] Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] - v68:[removeName, updateContainedComponent]
[UpdateTracker:9778251] Update Tracker - [Pathway:446652] Interleukin-1 family signaling - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778025] Update Tracker - [Pathway:5663020] Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) - v68:[updateContainedRLE]
[UpdateTracker:9900286] Update Tracker - [Complex:8854716] FLT3LG dimer:FLT3 dimer [plasma membrane] - v68:[modifyName]
[UpdateTracker:9900337] Update Tracker - [EntityWithAccessionedSequence:2466780] ABCA4 G1961E [photoreceptor disc membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778679] Update Tracker - [Pathway:5689901] Metalloprotease DUBs - v68:[updateContainedRLE]
[UpdateTracker:9778388] Update Tracker - [Pathway:8875360] InlB-mediated entry of Listeria monocytogenes into host cell - v68:[updateContainedRLE]
[UpdateTracker:9778629] Update Tracker - [Pathway:1234174] Cellular response to hypoxia - v68:[addLiteratureReference, add_removeHasEvent, modifyText, updateContainedRLE]
[UpdateTracker:9900099] Update Tracker - [Complex:8866844] ub-CFTR F508del [cytosol] - v68:[add_removeHasComponent]
[UpdateTracker:9778152] Update Tracker - [Pathway:422356] Regulation of insulin secretion - v68:[removeHasEvent, updateContainedPathway]
[UpdateTracker:9778087] Update Tracker - [FailedReaction:5623558] Defective SLC11A2 does not cotransport Fe2+, H+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9777856] Update Tracker - [FailedReaction:9036102] Defective UGT1A1 does not transfer GlcA from UDP-GlcA to BMG - v68:[addCatalystActivity]
[UpdateTracker:9778422] Update Tracker - [Pathway:8857538] PTK6 promotes HIF1A stabilization - v68:[addHasEvent, updateContainedRLE]
[UpdateTracker:9778034] Update Tracker - [Pathway:5423646] Aflatoxin activation and detoxification - v68:[addHasEvent]
[UpdateTracker:9778275] Update Tracker - [Pathway:5637815] Signaling by Ligand-Responsive EGFR Variants in Cancer - v68:[updateIndirectRLE]
[UpdateTracker:9778368] Update Tracker - [Pathway:69206] G1/S Transition - v68:[updateContainedPathway]
[UpdateTracker:9900087] Update Tracker - [Complex:5637694] p-5Y-EGFRvIII:GRB2:GAB1 [plasma membrane] - v68:[add_removeHasComponent, modifyName]
[UpdateTracker:9778044] Update Tracker - [Reaction:6807134] NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN - v68:[add_removeInput]
[UpdateTracker:9900326] Update Tracker - [Complex:9021593] ESRs:STRN:ESTG:MyrG-pY419-SRC [plasma membrane] - v68:[modifyName, updateContainedComponent]
[UpdateTracker:9900059] Update Tracker - [Complex:6783474] TYW5:Fe2+ [cytoplasm] - v68:[add_removeHasComponent]
[UpdateTracker:9778561] Update Tracker - [Pathway:180336] SHC1 events in EGFR signaling - v68:[updateContainedRLE]
[UpdateTracker:9900324] Update Tracker - [Complex:8985893] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] - v68:[add_removeHasComponent]
[UpdateTracker:9778448] Update Tracker - [Pathway:451478] ERK activation - v68:[add_removeHasEvent, modifyText]
[UpdateTracker:9778179] Update Tracker - [Pathway:181438] Toll Like Receptor 2 (TLR2) Cascade - v68:[updateIndirectRLE]
[UpdateTracker:9778467] Update Tracker - [FailedReaction:5656356] Defective SLC5A1 does not cotransport Glc and Na+ - v68:[addCatalystActivity]
[UpdateTracker:9778532] Update Tracker - [Pathway:425407] SLC-mediated transmembrane transport - v68:[updateContainedPathway]
[UpdateTracker:9900049] Update Tracker - [SimpleEntity:5250593] GD2 [synaptic vesicle membrane] - v68:[addName]
[UpdateTracker:9900228] Update Tracker - [DefinedSet:5228863] NFKBIA variants [cytosol] - v68:[add_removeHasMember]
[UpdateTracker:9778598] Update Tracker - [Pathway:5619078] Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C) - v68:[updateContainedRLE]
[UpdateTracker:9900128] Update Tracker - [Complex:8869174] pS-ADRB2:Catecholamine [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9778032] Update Tracker - [Pathway:5579013] Defective CYP7B1 causes SPG5A and CBAS3 - v68:[updateContainedRLE]
[UpdateTracker:9777986] Update Tracker - [FailedReaction:5610038] Defective GALT does not transfer UMP to Gal1P - v68:[addCatalystActivity]
[UpdateTracker:9778408] Update Tracker - [Pathway:5579028] Defective CYP17A1 causes AH5 - v68:[updateContainedRLE]
[UpdateTracker:9778369] Update Tracker - [Pathway:75815] Ubiquitin-dependent degradation of Cyclin D - v68:[add_removeHasEvent, modifyText]
[UpdateTracker:9778006] Update Tracker - [Pathway:8939902] Regulation of RUNX2 expression and activity - v68:[updateContainedRLE]
[UpdateTracker:9778460] Update Tracker - [Pathway:3282872] Severe congenital neutropenia type 4 (G6PC3) - v68:[updateContainedRLE]
[UpdateTracker:9778080] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v68:[updateContainedPathway]
[UpdateTracker:9777868] Update Tracker - [Reaction:381111] EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK - v68:[add_removeInput, add_removeOutput]
[UpdateTracker:9900248] Update Tracker - [EntityWithAccessionedSequence:8869143] pS-ADRB2 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778130] Update Tracker - [FailedReaction:5688025] Defective pro-SFTPB does not translocate from ER membrane to multivesicle body - v68:[add_removeInput, modifyText]
[UpdateTracker:9778194] Update Tracker - [Pathway:1643685] Disease - v68:[updateContainedPathway]
[UpdateTracker:9778276] Update Tracker - [Pathway:5576892] Phase 0 - rapid depolarisation - v68:[updateContainedRLE]
[UpdateTracker:9777976] Update Tracker - [Pathway:1236382] Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants - v68:[updateContainedRLE]
[UpdateTracker:9900138] Update Tracker - [Complex:9617306] Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778180] Update Tracker - [Pathway:5579016] Defective UGT1A4 causes hyperbilirubinemia - v68:[updateContainedRLE]
[UpdateTracker:9900225] Update Tracker - [EntityWithAccessionedSequence:8869111] SLC2A8 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900090] Update Tracker - [Complex:9617305] GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] - v68:[addHasComponent]
[UpdateTracker:9777883] Update Tracker - [Reaction:168140] Active IKK Complex phosphorylates NF-kappa-B inhibitor - v68:[addLiteratureReference]
[UpdateTracker:9900088] Update Tracker - [Complex:2033051] IgM Heavy Chain [plasma membrane] - v68:[add_removeHasComponent]
[UpdateTracker:9778366] Update Tracker - [FailedReaction:4793947] Defective MOGS does not cleave glucose from an N-glycosylated protein - v68:[addCatalystActivity]
[UpdateTracker:9777840] Update Tracker - [Pathway:1606322] ZBP1(DAI) mediated induction of type I IFNs - v68:[updateIndirectRLE]
[UpdateTracker:9777948] Update Tracker - [Pathway:450728] Inhibition of actin polymerisation - v68:[addHasEvent]
[UpdateTracker:9778615] Update Tracker - [Pathway:3656253] Defective EXT1 causes exostoses 1, TRPS2 and CHDS - v68:[updateContainedRLE]
[UpdateTracker:9778228] Update Tracker - [Pathway:9006927] Signaling by Non-Receptor Tyrosine Kinases - v68:[modifyText, updateContainedPathway]
[UpdateTracker:9778240] Update Tracker - [FailedReaction:3828061] Defective GYS1 does not transfer glucose to growing glycogen chains - v68:[addCatalystActivity]
[UpdateTracker:9778071] Update Tracker - [Pathway:156588] Glucuronidation - v68:[addHasEvent]
[UpdateTracker:9900250] Update Tracker - [Complex:8871150] PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9900205] Update Tracker - [EntityWithAccessionedSequence:8869127] TGOLN2 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777863] Update Tracker - [FailedReaction:5683672] Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body - v68:[addCatalystActivity]
[UpdateTracker:9900053] Update Tracker - [DefinedSet:8852852] (GlcNAc)2 (Man)9-5 [cytosol] - v68:[add_removeHasMember]
[UpdateTracker:9778164] Update Tracker - [Pathway:191650] Regulation of gap junction activity - v68:[addLiteratureReference, add_removeHasEvent, modifyText]
[UpdateTracker:9900181] Update Tracker - [Complex:9617327] GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:LRRC7:CaMKII dodecamer [plasma membrane] - v68:[addHasComponent, modifyName]
[UpdateTracker:9778411] Update Tracker - [FailedReaction:3322971] Defective MUT does not isomerise L-MM-CoA to SUCC-CoA - v68:[addCatalystActivity]
[UpdateTracker:9778031] Update Tracker - [Pathway:157858] Gap junction trafficking and regulation - v68:[updateContainedPathway]
[UpdateTracker:9778246] Update Tracker - [Pathway:5619089] Defective SLC6A5 causes hyperekplexia 3 (HKPX3) - v68:[updateContainedRLE]
[UpdateTracker:9778022] Update Tracker - [Pathway:4719377] Defective DPM2 causes DPM2-CDG - v68:[updateContainedRLE]
[UpdateTracker:9900357] Update Tracker - [Complex:8869165] EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9777940] Update Tracker - [FailedReaction:5651685] Defective SLC34A1 does not cotransport Pi, 3Na+ - v68:[addCatalystActivity]
[UpdateTracker:9900208] Update Tracker - [SimpleEntity:5228401] GD3 [plasma membrane] - v68:[addName]
[UpdateTracker:9778554] Update Tracker - [Pathway:3359478] Defective MUT causes MMAM - v68:[updateContainedRLE]
[UpdateTracker:9777921] Update Tracker - [FailedReaction:2263490] Defective GALNS does not hydrolyse sulfate from Gal6S in keratan sulfate - v68:[addCatalystActivity]
[UpdateTracker:9778005] Update Tracker - [FailedReaction:5649483] Defective PAH does not hydroxylate L-Phe to L-Tyr - v68:[addCatalystActivity]
[UpdateTracker:9778677] Update Tracker - [FailedReaction:5660694] Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9900060] Update Tracker - [DefinedSet:2033023] IgD or IgM [plasma membrane] - v68:[updateContainedMemberOrCandidate]
[UpdateTracker:9778644] Update Tracker - [Reaction:372705] Recruitment of BCAR1 to PTK2 complex - v68:[modifyText]
[UpdateTracker:9900135] Update Tracker - [SimpleEntity:6789106] 8,5'-cdA [cytoplasm] - v68:[add_removeReferenceEntity]
[UpdateTracker:9777930] Update Tracker - [Pathway:1630316] Glycosaminoglycan metabolism - v68:[updateContainedPathway]
[UpdateTracker:9778293] Update Tracker - [Pathway:2206296] MPS II - Hunter syndrome - v68:[updateContainedRLE]
[UpdateTracker:9777876] Update Tracker - [Pathway:68886] M Phase - v68:[updateContainedPathway]
[UpdateTracker:9778308] Update Tracker - [Pathway:5674404] PTEN Loss of Function in Cancer - v68:[updateContainedRLE]
[UpdateTracker:9900229] Update Tracker - [Complex:8869149] holoTF [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900113] Update Tracker - [SimpleEntity:6789053] 8,5'-cdG [cytoplasm] - v68:[add_removeReferenceEntity]
[UpdateTracker:9900118] Update Tracker - [SimpleEntity:6788977] nitryl chloride [phagocytic vesicle lumen] - v68:[add_removeReferenceEntity]
[UpdateTracker:9778406] Update Tracker - [Pathway:8985947] Interleukin-9 signaling - v68:[updateContainedRLE]
[UpdateTracker:9778413] Update Tracker - [Reaction:432537] PP2A dephosphorylates phosphorylated CLK - v68:[addLiteratureReference]
[UpdateTracker:9778124] Update Tracker - [FailedReaction:3595176] Defective CHSY1 does not transfer GalNAc to chondroitin - v68:[addCatalystActivity]
[UpdateTracker:9778088] Update Tracker - [Pathway:199991] Membrane Trafficking - v68:[updateContainedPathway]
[UpdateTracker:9778530] Update Tracker - [Pathway:381033] ATF6 (ATF6-alpha) activates chaperones - v68:[updateIndirectRLE]
[UpdateTracker:9778527] Update Tracker - [FailedReaction:5638222] Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region - v68:[addCatalystActivity]
[UpdateTracker:9778271] Update Tracker - [Pathway:5619052] Defective SLC9A9 causes autism 16 (AUTS16) - v68:[updateContainedRLE]
[UpdateTracker:9778195] Update Tracker - [FailedReaction:4341669] Defective NEU1 does not hydrolyse Neu5Ac from glycoconjugates - v68:[addCatalystActivity, add_removeInput]
[UpdateTracker:9900054] Update Tracker - [EntityWithAccessionedSequence:8869140] apoTF [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778480] Update Tracker - [Pathway:2142845] Hyaluronan metabolism - v68:[updateContainedPathway]
[UpdateTracker:9778540] Update Tracker - [Pathway:3315487] SMAD2/3 MH2 Domain Mutants in Cancer - v68:[removeHasEvent, updateContainedRLE]
[UpdateTracker:9778586] Update Tracker - [Reaction:8851011] TRIM27 polyubiquitinates PTEN - v68:[add_removeInput]
[UpdateTracker:9778556] Update Tracker - [Pathway:3828062] Glycogen storage disease type 0 (muscle GYS1) - v68:[updateContainedRLE]
[UpdateTracker:9778521] Update Tracker - [FailedReaction:5661039] Defective SLC9A6 does not exchange Na+ for H+ across the early endosome membrane - v68:[addCatalystActivity]
[UpdateTracker:9900167] Update Tracker - [Complex:1839062] Activated FGFR1 mutants and fusion:p-PLCG1 [cytosol] - v68:[updateContainedComponent]
[UpdateTracker:9900341] Update Tracker - [EntityWithAccessionedSequence:8871125] GGC-RAB5A [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900209] Update Tracker - [Complex:437191] PDPK1:PIP3:PRKCZ [plasma membrane] - v68:[modifyName]
[UpdateTracker:9778604] Update Tracker - [Pathway:1793185] Chondroitin sulfate/dermatan sulfate metabolism - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9777988] Update Tracker - [Reaction:437195] PDPK1 activates PRKCZ - v68:[modifyText]
[UpdateTracker:9778515] Update Tracker - [FailedReaction:5660890] Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu - v68:[addCatalystActivity]
[UpdateTracker:9778473] Update Tracker - [FailedReaction:9036052] Defective NAGLU does not hydrolyse heparan chain(2) - v68:[addCatalystActivity]
[UpdateTracker:9778197] Update Tracker - [Pathway:8876493] InlA-mediated entry of Listeria monocytogenes into host cells - v68:[updateContainedRLE]
[UpdateTracker:9777958] Update Tracker - [Pathway:199992] trans-Golgi Network Vesicle Budding - v68:[add_removeHasEvent, modifyText]
[UpdateTracker:9900140] Update Tracker - [EntityWithAccessionedSequence:2471751] RDH12 H151N [photoreceptor inner segment membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778224] Update Tracker - [FailedReaction:5615604] Defective POMT1 does not transfer Man from Dol-P-Man to DAG1 - v68:[addCatalystActivity]
[UpdateTracker:9778291] Update Tracker - [Pathway:390146] Hippo/Warts pathway - v68:[updateContainedPathway]
[UpdateTracker:9900224] Update Tracker - [EntityWithAccessionedSequence:5602517] IRAK4 E402TER [cytosol] - v68:[addName]
[UpdateTracker:9777903] Update Tracker - [Pathway:372790] Signaling by GPCR - v68:[updateContainedPathway]
[UpdateTracker:9900116] Update Tracker - [EntityWithAccessionedSequence:8869099] LRP2 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777971] Update Tracker - [FailedReaction:5678418] Defective ABCC9 (in KCNJ11:ABCC9) does not transport K+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778608] Update Tracker - [FailedReaction:5690340] Defective ABCC6 does not transport organic anion from cytosol to extracellular region - v68:[addCatalystActivity]
[UpdateTracker:9900273] Update Tracker - [DefinedSet:2471963] RBP4 mutants [extracellular region] - v68:[add_removeCompartment]
[UpdateTracker:9778213] Update Tracker - [Pathway:8876384] Listeria monocytogenes entry into host cells - v68:[updateIndirectRLE]
[UpdateTracker:9778454] Update Tracker - [FailedReaction:5661188] Defective SLCO2A1 does not transport PGT substrates from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778648] Update Tracker - [Pathway:4793950] Defective MAN1B1 causes MRT15 - v68:[updateContainedRLE]
[UpdateTracker:9778511] Update Tracker - [Pathway:73856] RNA Polymerase II Transcription Termination - v68:[add_removeHasEvent, modifyText]
[UpdateTracker:9900100] Update Tracker - [Complex:8869178] N4GlycoAsn-PalmS-WNT5A:FZD4 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777935] Update Tracker - [FailedReaction:9036020] Defective MPDU1 does not promote transfer of Man to (GlcNAc)2 (Man)8 (PP-Dol)1 by ALG9 - v68:[addRegulator]
[UpdateTracker:9900067] Update Tracker - [DefinedSet:8869151] VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778237] Update Tracker - [Reaction:421879] Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate - v68:[modifyText]
[UpdateTracker:9778285] Update Tracker - [Pathway:5668914] Diseases of metabolism - v68:[updateIndirectRLE]
[UpdateTracker:9900230] Update Tracker - [Complex:8876231] InlB:p-4Y-MET dimer [plasma membrane] - v68:[add_removeEntityOnOtherCell, removeCompartment, updateContainedComponent]
[UpdateTracker:9778272] Update Tracker - [Pathway:1222541] Cell redox homeostasis - v68:[updateContainedRLE]
[UpdateTracker:9778668] Update Tracker - [Pathway:4839726] Chromatin organization - v68:[updateContainedPathway]
[UpdateTracker:9778037] Update Tracker - [FailedReaction:5660910] Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane - v68:[addCatalystActivity]
[UpdateTracker:9778074] Update Tracker - [FailedReaction:3560804] Defective B4GALT7 does not transfer Gal to xylosyl-unit of the tetrasaccharide linker - v68:[addCatalystActivity]
[UpdateTracker:9778426] Update Tracker - [FailedReaction:9036050] Defective SGSH does not hydrolyse Heparan sulfate chain(2) - v68:[addCatalystActivity]
[UpdateTracker:9778465] Update Tracker - [FailedReaction:3878762] Defective GBE1 does not catalyze branch formation in growing glycogen chains (liver) - v68:[addCatalystActivity]
[UpdateTracker:9778517] Update Tracker - [Pathway:5688031] Defective pro-SFTPB causes SMDP1 and RDS - v68:[updateContainedRLE]
[UpdateTracker:9778305] Update Tracker - [Pathway:5576893] Phase 2 - plateau phase - v68:[updateContainedRLE]
[UpdateTracker:9900314] Update Tracker - [DefinedSet:9027374] Plcg1,2 [cytosol] - v68:[add_removeHasMember]
[UpdateTracker:9778101] Update Tracker - [Pathway:5619042] Defective RHAG causes regulator type Rh-null hemolytic anemia (RHN) - v68:[updateContainedRLE]
[UpdateTracker:9777911] Update Tracker - [FailedReaction:4719375] Defective DPM2 does not transfer mannose to DOLP to form DOLPman - v68:[addCatalystActivity]
[UpdateTracker:9777832] Update Tracker - [FailedReaction:3814838] Defective GYG1 is not autoglucosyolated - v68:[addCatalystActivity]
[UpdateTracker:9777968] Update Tracker - [Pathway:3560792] Defective SLC26A2 causes chondrodysplasias - v68:[updateContainedRLE]
[UpdateTracker:9900098] Update Tracker - [EntityWithAccessionedSequence:9628518] IKBKB Q432Pfs*62 [cytosol] - v68:[addDisease]
[UpdateTracker:9778046] Update Tracker - [Pathway:5619068] Defective SLC2A10 causes arterial tortuosity syndrome (ATS) - v68:[updateContainedRLE]
[UpdateTracker:9778288] Update Tracker - [Pathway:5609975] Diseases associated with glycosylation precursor biosynthesis - v68:[updateIndirectRLE]
[UpdateTracker:9778173] Update Tracker - [Pathway:5609974] Defective PGM1 causes PGM1-CDG - v68:[updateContainedRLE]
[UpdateTracker:9778050] Update Tracker - [Pathway:450282] MAPK targets/ Nuclear events mediated by MAP kinases - v68:[updateIndirectRLE]
[UpdateTracker:9778268] Update Tracker - [Pathway:5619049] Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages) - v68:[updateContainedRLE]
[UpdateTracker:9778334] Update Tracker - [Pathway:2206302] MPS I - Hurler syndrome - v68:[updateContainedRLE]
[UpdateTracker:9778601] Update Tracker - [Pathway:5619084] ABC transporter disorders - v68:[updateIndirectRLE]
[UpdateTracker:9778348] Update Tracker - [FailedReaction:4570573] Defective RFT1 does not flip the N-glycan precursor - v68:[addCatalystActivity]
[UpdateTracker:9900178] Update Tracker - [Complex:9628279] Gly,D-Ser:L-Glu:GRIN1:p-Y-GRIN2 NMDA receptors [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9777904] Update Tracker - [Pathway:5083630] Defective LFNG causes SCDO3 - v68:[updateContainedRLE]
[UpdateTracker:9900185] Update Tracker - [EntityWithAccessionedSequence:75379] Rdh8 [photoreceptor outer segment membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778613] Update Tracker - [FailedReaction:2317387] PTEN cancer mutants do not dephosphorylate PIP3 - v68:[addCatalystActivity]
[UpdateTracker:9777865] Update Tracker - [FailedReaction:2265534] Defective GLB1 does not hydrolyse a glycosaminoglycan - v68:[addCatalystActivity]
[UpdateTracker:9778047] Update Tracker - [Pathway:3814836] Glycogen storage disease type XV (GYG1) - v68:[updateContainedRLE]
[UpdateTracker:9778060] Update Tracker - [Pathway:418594] G alpha (i) signalling events - v68:[updateContainedRLE]
[UpdateTracker:9777937] Update Tracker - [Reaction:437185] PDK1 activates PKC zeta - v68:[modifyText]
[UpdateTracker:9900121] Update Tracker - [SimpleEntity:1605590] GM3 [cytosol] - v68:[addName]
[UpdateTracker:9900188] Update Tracker - [Complex:180610] PIC anchored to the NPC [nuclear envelope] - v68:[updateContainedComponent]
[UpdateTracker:9778504] Update Tracker - [Pathway:5579004] Defective CYP26C1 causes FFDD4 - v68:[updateContainedRLE]
[UpdateTracker:9900110] Update Tracker - [EntityWithAccessionedSequence:8869100] M6PR [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778606] Update Tracker - [Pathway:5619076] Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25) - v68:[updateContainedRLE]
[UpdateTracker:9778115] Update Tracker - [Pathway:69613] p53-Independent G1/S DNA damage checkpoint - v68:[updateContainedPathway]
[UpdateTracker:9900071] Update Tracker - [EntityWithAccessionedSequence:8869091] IGF2R [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778083] Update Tracker - [Pathway:3560783] Defective B4GALT7 causes EDS, progeroid type - v68:[updateContainedRLE]
[UpdateTracker:9778232] Update Tracker - [FailedReaction:5659922] Defective SI does not hydrolyze Mal - v68:[addCatalystActivity]
[UpdateTracker:9900151] Update Tracker - [Complex:8871139] GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9778452] Update Tracker - [Pathway:418597] G alpha (z) signalling events - v68:[updateContainedRLE]
[UpdateTracker:9778243] Update Tracker - [Reaction:5617143] B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA - v68:[modifyText]
[UpdateTracker:9778410] Update Tracker - [Pathway:400206] Regulation of lipid metabolism by PPARalpha - v68:[updateIndirectRLE]
[UpdateTracker:9777919] Update Tracker - [FailedReaction:5602050] Defective CYP26C1 does not 4-hydroxylate 9cRA - v68:[addCatalystActivity]
[UpdateTracker:9778166] Update Tracker - [Reaction:5694433] MIA2 binds PREB - v68:[add_removeInput, modifyText]
[UpdateTracker:9778210] Update Tracker - [Pathway:2980766] Nuclear Envelope Breakdown - v68:[add_removeHasEvent, modifyText, updateContainedRLE]
[UpdateTracker:9900210] Update Tracker - [Complex:8943019] Ub:UBE2N [nucleoplasm] - v68:[add_removeHasComponent]
[UpdateTracker:9900061] Update Tracker - [Complex:8877011] Ub-K,p-Y-753,Y754-CDH1(155-882):Ca2+ dimer [plasma membrane] - v68:[addHasComponent]
[UpdateTracker:9777950] Update Tracker - [Reaction:1222412] lpdC dimer reactivates dlaT - v68:[modifyText]
[UpdateTracker:9900347] Update Tracker - [Complex:8876228] InlB:p-4Y-MET [plasma membrane] - v68:[addDisease, add_removeEntityOnOtherCell, add_removeHasComponent, removeCompartment]
[UpdateTracker:9778614] Update Tracker - [Pathway:977444] GABA B receptor activation - v68:[updateContainedPathway]
[UpdateTracker:9778497] Update Tracker - [Reaction:201457] BMP2 binds to the receptor complex - v68:[removeCatalystActivity]
[UpdateTracker:9778441] Update Tracker - [FailedReaction:5621402] Defective CP does not oxidise Fe2+ to Fe3+ - v68:[addCatalystActivity]
[UpdateTracker:9777831] Update Tracker - [Pathway:5579010] Defective CYP24A1 causes HCAI - v68:[updateContainedRLE]
[UpdateTracker:9777867] Update Tracker - [Pathway:2206307] MPS IIIA - Sanfilippo syndrome A - v68:[updateContainedRLE]
[UpdateTracker:9778207] Update Tracker - [Pathway:2160916] Hyaluronan uptake and degradation - v68:[addHasEvent]
[UpdateTracker:9778012] Update Tracker - [Pathway:5619061] Defective SLC33A1 causes spastic paraplegia 42 (SPG42) - v68:[updateContainedRLE]
[UpdateTracker:9778560] Update Tracker - [FailedReaction:5621888] Defective HK1 does not phosphorylate Glc to form G6P - v68:[addCatalystActivity]
[UpdateTracker:9778379] Update Tracker - [Pathway:209459] Imd pathway - v68:[add_removeHasEvent, updateContainedPathway]
[UpdateTracker:9778541] Update Tracker - [Pathway:3656234] Defective HEXA causes GM2G1 - v68:[updateContainedRLE]
[UpdateTracker:9900065] Update Tracker - [DefinedSet:2466752] ABCA4 mutants [photoreceptor disc membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900133] Update Tracker - [Complex:8869185] LRP2:DAB2 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778113] Update Tracker - [Pathway:1300645] Acrosome Reaction and Sperm:Oocyte Membrane Binding - v68:[addHasEvent, modifyText]
[UpdateTracker:9900349] Update Tracker - [Complex:157712] Nup62 Complex [nuclear envelope] - v68:[add_removeHasComponent]
[UpdateTracker:9778206] Update Tracker - [FailedReaction:5649742] Defective SLC33A1 does not transport Ac-CoA from cytosol to Golgi lumen - v68:[addCatalystActivity]
[UpdateTracker:9900091] Update Tracker - [Complex:8869172] SYT8 dimer [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778338] Update Tracker - [Pathway:5619108] Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS) - v68:[updateContainedRLE]
[UpdateTracker:9777987] Update Tracker - [FailedReaction:3656261] Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain - v68:[addCatalystActivity]
[UpdateTracker:9777946] Update Tracker - [Reaction:8948775] MKRN1 polyubiquitinates PTEN - v68:[add_removeInput]
[UpdateTracker:9900336] Update Tracker - [Complex:8876242] InlB:p-4Y-MET dimer:GRB2-1:CBL [plasma membrane] - v68:[add_removeEntityOnOtherCell, removeCompartment, updateContainedComponent]
[UpdateTracker:9778505] Update Tracker - [FailedReaction:5653850] Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778112] Update Tracker - [FailedReaction:5623588] Defective SLC12A1 does not cotransport Na+, K+, 2Cl- from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9777862] Update Tracker - [Pathway:5619044] Defective SLC6A19 causes Hartnup disorder (HND) - v68:[updateContainedRLE]
[UpdateTracker:9900293] Update Tracker - [SimpleEntity:29406] 2OG [cytosol] - v68:[add_removeReferenceEntity]
[UpdateTracker:9778434] Update Tracker - [BlackBoxEvent:452838] Expression of NANOG - v68:[removeCatalystActivity]
[UpdateTracker:9778425] Update Tracker - [Pathway:5619066] Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1) - v68:[updateContainedRLE]
[UpdateTracker:9900186] Update Tracker - [Complex:8854215] RAB35:GDP [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900247] Update Tracker - [Complex:9614253] Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778147] Update Tracker - [Reaction:5577237] KCNH2:KCNE transport K+ from cytosol to extracellular region - v68:[addRegulator]
[UpdateTracker:9778167] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9900146] Update Tracker - [Complex:8869167] SYT9 dimer [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778098] Update Tracker - [Pathway:6791462] TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P - v68:[updateContainedRLE]
[UpdateTracker:9900274] Update Tracker - [Complex:8943008] Ub:UBE2N:UBE2V2 [nucleoplasm] - v68:[updateContainedComponent]
[UpdateTracker:9778357] Update Tracker - [Pathway:381119] Unfolded Protein Response (UPR) - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9900137] Update Tracker - [Complex:9607223] Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] - v68:[modifyName, updateContainedComponent]
[UpdateTracker:9778095] Update Tracker - [Pathway:5619035] Defective SLC17A5 causes Salla disease (SD) and ISSD - v68:[updateContainedRLE]
[UpdateTracker:9777929] Update Tracker - [FailedReaction:2206299] Defective IDUA does not hydrolyse Heparan sulfate chain(6) - v68:[addCatalystActivity]
[UpdateTracker:9778064] Update Tracker - [Pathway:5083636] Defective GALNT12 causes CRCS1 - v68:[updateContainedRLE]
[UpdateTracker:9778175] Update Tracker - [Pathway:71291] Metabolism of amino acids and derivatives - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9777918] Update Tracker - [Reaction:5690157] USP16,USP21 deubiquitinate Histone H2A - v68:[add_removeOutput]
[UpdateTracker:9900204] Update Tracker - [DefinedSet:8868710] CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedMemberOrCandidate]
[UpdateTracker:9900119] Update Tracker - [EntityWithAccessionedSequence:8869115] SYT11 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900260] Update Tracker - [Complex:8869194] DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9778303] Update Tracker - [Pathway:8941858] Regulation of RUNX3 expression and activity - v68:[updateContainedRLE]
[UpdateTracker:9778559] Update Tracker - [Pathway:2206281] Mucopolysaccharidoses - v68:[updateIndirectRLE]
[UpdateTracker:9778208] Update Tracker - [Pathway:181431] Acetylcholine binding and downstream events - v68:[addLiteratureReference, add_removeHasEvent, modifyText]
[UpdateTracker:9778073] Update Tracker - [FailedReaction:5621918] Defective GCK does not phosphorylate Glc to form G6P - v68:[addCatalystActivity]
[UpdateTracker:9900297] Update Tracker - [Complex:8869176] AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778670] Update Tracker - [Pathway:168325] Viral Messenger RNA Synthesis - v68:[removeHasEvent, updateContainedRLE]
[UpdateTracker:9900047] Update Tracker - [Complex:159259] NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] - v68:[updateContainedComponent]
[UpdateTracker:9778359] Update Tracker - [Pathway:4793952] Defective MGAT2 causes CDG-2a - v68:[updateContainedRLE]
[UpdateTracker:9777984] Update Tracker - [Pathway:2024101] CS/DS degradation - v68:[addHasEvent]
[UpdateTracker:9778111] Update Tracker - [FailedReaction:3323184] Defective HLCS does not biotinylate ACACA:Mn2+ - v68:[addCatalystActivity]
[UpdateTracker:9778131] Update Tracker - [Pathway:5619077] Defective SLC24A1 causes congenital stationary night blindness 1D (CSNB1D) - v68:[updateContainedRLE]
[UpdateTracker:9900187] Update Tracker - [SimpleEntity:1605641] GM3 [lysosomal lumen] - v68:[addName]
[UpdateTracker:9778191] Update Tracker - [Pathway:5619098] Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS) - v68:[updateContainedRLE]
[UpdateTracker:9777953] Update Tracker - [Reaction:5690080] USP3,SAGA deubiquitinate Histone H2A,H2B - v68:[add_removeOutput]
[UpdateTracker:9778093] Update Tracker - [Reaction:354073] Autophosphorylation of PTK2 at Y397 - v68:[modifyText]
[UpdateTracker:9900329] Update Tracker - [DefinedSet:5672601] RAS GEFs [plasma membrane] - v68:[updateContainedMemberOrCandidate]
[UpdateTracker:9778000] Update Tracker - [Pathway:1187000] Fertilization - v68:[removeHasEvent, updateContainedPathway]
[UpdateTracker:9777875] Update Tracker - [FailedReaction:3797226] Defective NHLRC1 does not ubiquitinate EPM2A (laforin) and PPP1R3C (PTG) (type 2B disease) - v68:[addCatalystActivity]
[UpdateTracker:9778039] Update Tracker - [FailedReaction:5603208] Defective OPLAH does not hydrolyse OPRO - v68:[addCatalystActivity]
[UpdateTracker:9900345] Update Tracker - [Complex:1226013] Ligand-responsive p-6Y-EGFR mutants:GRB2:GAB1:PI3K [plasma membrane] - v68:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9778421] Update Tracker - [Pathway:3656534] Loss of Function of TGFBR1 in Cancer - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9900334] Update Tracker - [Complex:9606627] Active FLT3:GRB2:p-Y-GAB2 [plasma membrane] - v68:[modifyName, updateContainedComponent]
[UpdateTracker:9900351] Update Tracker - [Complex:2033037] IgD [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778635] Update Tracker - [Pathway:3906995] Diseases associated with O-glycosylation of proteins - v68:[updateIndirectRLE]
[UpdateTracker:9777888] Update Tracker - [Pathway:2206292] MPS VII - Sly syndrome - v68:[updateContainedRLE]
[UpdateTracker:9778620] Update Tracker - [Pathway:450724] JNK signalling - v68:[removeHasEvent, updateContainedPathway]
[UpdateTracker:9777995] Update Tracker - [Pathway:525793] Myogenesis - v68:[addLiteratureReference, add_removeHasEvent, modifyText]
[UpdateTracker:9778630] Update Tracker - [Pathway:198753] ERK/MAPK targets - v68:[updateContainedRLE]
[UpdateTracker:9778290] Update Tracker - [Pathway:69601] Ubiquitin Mediated Degradation of Phosphorylated Cdc25A - v68:[removeHasEvent]
[UpdateTracker:9778132] Update Tracker - [FailedReaction:5660015] Defective RPIA does not isomerize R5P to RU5P - v68:[addCatalystActivity]
[UpdateTracker:9777892] Update Tracker - [Reaction:8875431] LRIG1 undergoes ubiquitination - v68:[add_removeInput]
[UpdateTracker:9778217] Update Tracker - [FailedReaction:5483229] HHAT G287V doesn't palmitoylate Hh-Np - v68:[addCatalystActivity]
[UpdateTracker:9778048] Update Tracker - [FailedReaction:3656269] Defective CHST6 does not transfer SO4(2-) to GlcNAc residues on keratan-PG - v68:[addCatalystActivity]
[UpdateTracker:9900122] Update Tracker - [SimpleEntity:71067] Fe2+ [cytosol] - v68:[add_removeReferenceEntity]
[UpdateTracker:9777999] Update Tracker - [Pathway:5619056] Defective HK1 causes hexokinase deficiency (HK deficiency) - v68:[updateContainedRLE]
[UpdateTracker:9778597] Update Tracker - [BlackBoxEvent:381128] Translation of ATF4 - v68:[addLiteratureReference, add_removeRegulator, modifyText]
[UpdateTracker:9778319] Update Tracker - [BlackBoxEvent:1989767] Expression of TRIB3 - v68:[add_removeOutput]
[UpdateTracker:9778633] Update Tracker - [BlackBoxEvent:8850992] Proteasome degrades polyubiquitinated PTEN - v68:[add_removeOutput]
[UpdateTracker:9900270] Update Tracker - [EntityWithAccessionedSequence:8854153] RAB35 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778399] Update Tracker - [Pathway:4551295] Defective ALG11 causes CDG-1p - v68:[updateContainedRLE]
[UpdateTracker:9778244] Update Tracker - [FailedReaction:5625029] SLC1A1 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9777900] Update Tracker - [FailedReaction:2318373] Defective GUSB does not hydrolyse (HA)2 - v68:[addCatalystActivity]
[UpdateTracker:9777908] Update Tracker - [Pathway:1430728] Metabolism - v68:[updateContainedPathway]
[UpdateTracker:9900325] Update Tracker - [GenomeEncodedEntity:9604605] Unknown protein kinase [nucleoplasm] - v68:[modifyName]
[UpdateTracker:9778625] Update Tracker - [FailedReaction:5661086] Defective SLC9A9 does not exchange Na+ for H+ across the late endosome membrane - v68:[addCatalystActivity]
[UpdateTracker:9900235] Update Tracker - [CandidateSet:4127419] RDH8-like proteins [photoreceptor outer segment membrane] - v68:[add_removeHasMember]
[UpdateTracker:9778567] Update Tracker - [FailedReaction:3791349] Defective EPM2A does not dephosphorylate phosphoglycogen (type 2A disease) - v68:[addCatalystActivity]
[UpdateTracker:9777961] Update Tracker - [Pathway:6791461] RPIA deficiency: failed conversion of RU5P to R5P - v68:[updateContainedRLE]
[UpdateTracker:9900086] Update Tracker - [EntityWithAccessionedSequence:209969] CYP24A1 [mitochondrial inner membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778153] Update Tracker - [Pathway:156580] Phase II - Conjugation of compounds - v68:[updateContainedPathway]
[UpdateTracker:9778377] Update Tracker - [Reaction:354066] Translocation of PTK2 to Focal complexes - v68:[modifyText]
[UpdateTracker:9778265] Update Tracker - [Pathway:382556] ABC-family proteins mediated transport - v68:[updateContainedRLE]
[UpdateTracker:9778367] Update Tracker - [Pathway:209405] JAK/STAT pathway - v68:[add_removeHasEvent]
[UpdateTracker:9778351] Update Tracker - [Pathway:437987] Toll-like receptors (TLR) cascades - v68:[updateContainedPathway]
[UpdateTracker:9777957] Update Tracker - [Pathway:201451] Signaling by BMP - v68:[updateContainedRLE]
[UpdateTracker:9777932] Update Tracker - [Pathway:5637812] Signaling by EGFRvIII in Cancer - v68:[updateIndirectRLE]
[UpdateTracker:9778657] Update Tracker - [Reaction:212356] Formation of CSL-NICD coactivator complex - v68:[add_removeInput]
[UpdateTracker:9778127] Update Tracker - [Pathway:70326] Glucose metabolism - v68:[updateContainedPathway]
[UpdateTracker:9778149] Update Tracker - [Reaction:4084999] NEU1 hydrolyses Neu5Ac from glycoconjugates - v68:[add_removeInput]
[UpdateTracker:9777978] Update Tracker - [BlackBoxEvent:452894] Expression of SOX2 - v68:[removeCatalystActivity]
[UpdateTracker:9778440] Update Tracker - [Pathway:5603029] IkBA variant leads to EDA-ID - v68:[addHasEvent, modifyText, updateContainedRLE]
[UpdateTracker:9900233] Update Tracker - [Complex:429424] Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9777884] Update Tracker - [Pathway:4043916] Defective MPI causes MPI-CDG - v68:[updateContainedRLE]
[UpdateTracker:9777849] Update Tracker - [Pathway:5579030] Defective CYP19A1 causes AEXS - v68:[updateContainedRLE]
[UpdateTracker:9777838] Update Tracker - [Pathway:3108232] SUMO E3 ligases SUMOylate target proteins - v68:[modifyText]
[UpdateTracker:9777835] Update Tracker - [Reaction:2408546] tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex - v68:[modifyText]
[UpdateTracker:9778327] Update Tracker - [Pathway:5678771] Defective ABCB4 causes PFIC3, ICP3 and GBD1 - v68:[updateContainedRLE]
[UpdateTracker:9778176] Update Tracker - [Reaction:8854041] SCF-FBXL7 ubiquitinates AURKA - v68:[add_removeInput]
[UpdateTracker:9778302] Update Tracker - [Pathway:170670] Adenylate cyclase inhibitory pathway - v68:[addLiteratureReference]
[UpdateTracker:9900264] Update Tracker - [DefinedSet:188019] PI3K-containing complexes [cytosol] - v68:[addCompartment, updateContainedMemberOrCandidate]
[UpdateTracker:9900302] Update Tracker - [Complex:8868626] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9778097] Update Tracker - [FailedReaction:5626356] Defective SLC24A5 does not exchange cytosolic 4Na+ for Golgi luminal Ca2+, K+ - v68:[addCatalystActivity]
[UpdateTracker:9777830] Update Tracker - [FailedReaction:9036046] Defective IDS does not hydrolyse Heparan sulfate chain(5) - v68:[addCatalystActivity]
[UpdateTracker:9900074] Update Tracker - [EntityWithAccessionedSequence:2466827] ABCA4 R943Q [photoreceptor disc membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778190] Update Tracker - [FailedReaction:9035990] Defective HLCS does not biotinylate 6x(PCCA:PCCB) - v68:[addCatalystActivity]
[UpdateTracker:9778033] Update Tracker - [FailedReaction:5678517] Defective ABCB11 does not transport bile salts from cytosol to extracellular region - v68:[addCatalystActivity]
[UpdateTracker:9778181] Update Tracker - [FailedReaction:9608288] Defective MUTYH mutants do not bind adenine mispaired with 8-oxoguanine - v68:[add_removeInput]
[UpdateTracker:9777906] Update Tracker - [Pathway:69278] Cell Cycle, Mitotic - v68:[updateContainedPathway]
[UpdateTracker:9777891] Update Tracker - [Pathway:162582] Signal Transduction - v68:[updateContainedPathway]
[UpdateTracker:9900044] Update Tracker - [EntityWithAccessionedSequence:8869109] SLC18A3 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777927] Update Tracker - [FailedReaction:5658163] Defective SLC5A2 does not cotransport Glc and Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778424] Update Tracker - [Reaction:5694436] MIA2 and MIA3 dissociate from procollagen VII vesicle - v68:[modifyText]
[UpdateTracker:9778654] Update Tracker - [FailedReaction:5602966] Defective FMO3 does not N-oxidise TMA - v68:[addCatalystActivity]
[UpdateTracker:9778416] Update Tracker - [Pathway:5683678] Defective ABCA3 causes SMDP3 - v68:[updateContainedRLE]
[UpdateTracker:9778680] Update Tracker - [Reaction:1226012] Binding of PI3K to complex of GRB2:GAB1 and ligand-responsive p-6Y-EGFR mutants - v68:[add_removeInput, modifyText]
[UpdateTracker:9778442] Update Tracker - [FailedReaction:4755545] Defective DHDDS does not elongate E,E-FPP - v68:[addCatalystActivity]
[UpdateTracker:9900236] Update Tracker - [Complex:354080] Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] - v68:[modifyName, updateContainedComponent]
[UpdateTracker:9778322] Update Tracker - [Reaction:198706] ERK1/2 activates ELK1 - v68:[modifyText]
[UpdateTracker:9900238] Update Tracker - [Complex:1839061] Activated FGFR1 mutants and fusions:PLCG1 [cytosol] - v68:[updateContainedComponent]
[UpdateTracker:9777861] Update Tracker - [FailedReaction:4549334] Defective DPAGT1 does not transfer GlcNAc to DOLP - v68:[addCatalystActivity]
[UpdateTracker:9900148] Update Tracker - [Complex:354135] Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] - v68:[modifyName, updateContainedComponent]
[UpdateTracker:9778563] Update Tracker - [Pathway:5619081] Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) - v68:[updateContainedRLE]
[UpdateTracker:9900076] Update Tracker - [DefinedSet:2471705] RDH12 mutants [photoreceptor inner segment membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778589] Update Tracker - [Reaction:109536] Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 - v68:[add_removeInput, add_removeOutput]
[UpdateTracker:9778642] Update Tracker - [Pathway:975155] MyD88 dependent cascade initiated on endosome - v68:[updateContainedPathway]
[UpdateTracker:9778003] Update Tracker - [Pathway:8878159] Transcriptional regulation by RUNX3 - v68:[updateIndirectRLE]
[UpdateTracker:9778318] Update Tracker - [Pathway:9609507] Protein localization - v68:[addHasEvent]
[UpdateTracker:9778494] Update Tracker - [FailedReaction:5579081] Defective ACY1 does not hydrolyse mercapturic acids - v68:[addCatalystActivity]
[UpdateTracker:9900315] Update Tracker - [EntityWithAccessionedSequence:2471667] RDH12 Q189X [photoreceptor inner segment membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900046] Update Tracker - [Complex:164386] G-beta:G-gamma dimer [plasma membrane] - v68:[add_removeHasComponent]
[UpdateTracker:9900239] Update Tracker - [SimpleEntity:159939] SUCCA [nucleoplasm] - v68:[add_removeReferenceEntity]
[UpdateTracker:9900108] Update Tracker - [EntityWithAccessionedSequence:9628815] EPGN(23-154) [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900328] Update Tracker - [DefinedSet:8869159] AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedMemberOrCandidate]
[UpdateTracker:9778085] Update Tracker - [Reaction:8952382] MDM2 polyubiquitinates RUNX3 - v68:[add_removeInput]
[UpdateTracker:9778220] Update Tracker - [Pathway:1222499] Latent infection - Other responses of Mtb to phagocytosis - v68:[updateIndirectRLE]
[UpdateTracker:9778605] Update Tracker - [Pathway:4717374] Defective DPM1 causes DPM1-CDG - v68:[updateContainedRLE]
[UpdateTracker:9778030] Update Tracker - [FailedReaction:9036285] Defective EXT1 (in EXT1:EXT2) does not transfer GlcA to heparan - v68:[addCatalystActivity]
[UpdateTracker:9778248] Update Tracker - [Reaction:392129] Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate - v68:[modifyText]
[UpdateTracker:9777994] Update Tracker - [Pathway:2022870] Chondroitin sulfate biosynthesis - v68:[addHasEvent]
[UpdateTracker:9778501] Update Tracker - [Pathway:5083625] Defective GALNT3 causes HFTC - v68:[updateContainedRLE]
[UpdateTracker:9778233] Update Tracker - [Pathway:1679131] Trafficking and processing of endosomal TLR - v68:[updateContainedRLE]
[UpdateTracker:9778309] Update Tracker - [Pathway:5578995] Defective TPMT causes TPMT deficiency - v68:[updateContainedRLE]
[UpdateTracker:9778330] Update Tracker - [Pathway:442755] Activation of NMDA receptors and postsynaptic events - v68:[addHasEvent, updateIndirectRLE]
[UpdateTracker:9778078] Update Tracker - [Reaction:1225949] Binding of CBL to ligand-responsive p-6Y-EGFR mutants - v68:[add_removeInput]
[UpdateTracker:9900161] Update Tracker - [Complex:9618649] Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778284] Update Tracker - [Pathway:6809583] Retinoid metabolism disease events - v68:[updateContainedRLE]
[UpdateTracker:9778498] Update Tracker - [Pathway:83936] Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane - v68:[addHasEvent, updateContainedRLE]
[UpdateTracker:9900332] Update Tracker - [DefinedSet:5688020] pro-SFTPB mutants [endoplasmic reticulum membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778581] Update Tracker - [Pathway:166166] MyD88-independent TLR4 cascade - v68:[updateContainedPathway]
[UpdateTracker:9778415] Update Tracker - [Pathway:73929] Base-Excision Repair, AP Site Formation - v68:[addHasEvent, updateContainedPathway]
[UpdateTracker:9900261] Update Tracker - [EntityWithAccessionedSequence:8869097] LDLRAP1 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900149] Update Tracker - [Complex:2064263] CSL NCOR co-repressor complex [nucleoplasm] - v68:[add_removeHasComponent]
[UpdateTracker:9778450] Update Tracker - [Pathway:4793954] Defective MOGS causes CDG-2b - v68:[updateContainedRLE]
[UpdateTracker:9777854] Update Tracker - [Pathway:5689880] Ub-specific processing proteases - v68:[updateContainedRLE]
[UpdateTracker:9900201] Update Tracker - [DefinedSet:6785476] processed tRNA [cytosol] - v68:[modifyName]
[UpdateTracker:9778499] Update Tracker - [BlackBoxEvent:983427] Expression of peptide bound class I MHC on cell surface - v68:[modifyText]
[UpdateTracker:9778403] Update Tracker - [BlackBoxEvent:452392] Transcription of POU5F1 (OCT4) - v68:[removeCatalystActivity]
[UpdateTracker:9900169] Update Tracker - [Complex:8876211] InlB:MET dimer [plasma membrane] - v68:[add_removeEntityOnOtherCell, updateContainedComponent]
[UpdateTracker:9778204] Update Tracker - [FailedReaction:5688397] Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body - v68:[addCatalystActivity]
[UpdateTracker:9900256] Update Tracker - [SimpleEntity:8869056] ADR [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777926] Update Tracker - [FailedReaction:5632871] Defective SLC2A10 does not transport Glc from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9900223] Update Tracker - [EntityWithAccessionedSequence:9028500] IL7R [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900318] Update Tracker - [Complex:165531] Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP:NPC [nuclear envelope] - v68:[updateContainedComponent]
[UpdateTracker:9778578] Update Tracker - [FailedReaction:5651971] Defective SLC34A3 does not cotransport Pi, 2Na+ - v68:[addCatalystActivity]
[UpdateTracker:9777934] Update Tracker - [Pathway:450799] RHO1 signalling - v68:[updateContainedPathway]
[UpdateTracker:9778140] Update Tracker - [FailedReaction:9035949] Defective B4GALT1 does not transfer Gal to the N-glycan precursor - v68:[addCatalystActivity]
[UpdateTracker:9778385] Update Tracker - [Reaction:8877003] CBLL1 ubiqutinates the InlA-bound CDH1 complex - v68:[add_removeInput]
[UpdateTracker:9778146] Update Tracker - [Pathway:5689603] UCH proteinases - v68:[updateContainedRLE]
[UpdateTracker:9778105] Update Tracker - [FailedReaction:5652099] Defective SLC35A2 does not exchange UDP-Gal, UDP-GalNAc for UMP - v68:[addCatalystActivity]
[UpdateTracker:9778226] Update Tracker - [Pathway:3560782] Diseases associated with glycosaminoglycan metabolism - v68:[updateIndirectRLE]
[UpdateTracker:9778286] Update Tracker - [BlackBoxEvent:8866858] CFTR F508del is degraded by the 26S proteasome - v68:[add_removeOutput]
[UpdateTracker:9900073] Update Tracker - [Complex:8866535] Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778523] Update Tracker - [Pathway:452723] Transcriptional regulation of pluripotent stem cells - v68:[updateContainedRLE]
[UpdateTracker:9778014] Update Tracker - [Pathway:4719360] Defective DPM3 causes DPM3-CDG - v68:[updateContainedRLE]
[UpdateTracker:9778245] Update Tracker - [FailedReaction:3636919] Defective CHST14 does not transfer SO4(2-) to GalNAc in dermatan or DS - v68:[addCatalystActivity]
[UpdateTracker:9778340] Update Tracker - [FailedReaction:4225086] Defective mitochondrial BTD does not hydrolyse BCTN - v68:[addCatalystActivity]
[UpdateTracker:9778238] Update Tracker - [Pathway:383280] Nuclear Receptor transcription pathway - v68:[addHasEvent]
[UpdateTracker:9900237] Update Tracker - [Complex:9611369] GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] - v68:[addHasComponent]
[UpdateTracker:9778487] Update Tracker - [FailedReaction:5683325] Defective ABCD4:LMBRD1 does not transport Cbl from lysosomal lumen to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9900097] Update Tracker - [SimpleEntity:8855489] OSCN- [extracellular region] - v68:[add_removeReferenceEntity]
[UpdateTracker:9900296] Update Tracker - [Complex:8876257] InlB:MonoUb-K,p-4Y-MET dimer [plasma membrane] - v68:[add_removeEntityOnOtherCell, removeCompartment, updateContainedComponent]
[UpdateTracker:9900234] Update Tracker - [EntityWithAccessionedSequence:157736] NUP58-1 [nuclear envelope] - v68:[addName]
[UpdateTracker:9778482] Update Tracker - [FailedReaction:3322125] Defective MMAB does not transfer adenosyl group from ATP to B12s - v68:[addCatalystActivity]
[UpdateTracker:9900183] Update Tracker - [Complex:879260] mca:Zn2+ [cytosol] - v68:[add_removeHasComponent, modifyName]
[UpdateTracker:9778234] Update Tracker - [FailedReaction:5628807] Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778570] Update Tracker - [Pathway:991365] Activation of GABAB receptors - v68:[add_removeHasEvent, updateContainedPathway]
[UpdateTracker:9778483] Update Tracker - [BlackBoxEvent:8854071] Proteasome-mediated degradation of PolyUb-FBXL7 - v68:[add_removeOutput]
[UpdateTracker:9900125] Update Tracker - [SimpleEntity:1650774] Fe2+ [endoplasmic reticulum lumen] - v68:[add_removeReferenceEntity, removeName]
[UpdateTracker:9778456] Update Tracker - [FailedReaction:3656523] An anchoring protein ZFYVE9 (SARA) does not recruit SMAD2/3 to TGFB1:TGFBR2:p-TGFBR1 KD Mutants - v68:[modifyText]
[UpdateTracker:9778587] Update Tracker - [FailedReaction:9035982] Defective HEXB does not cleave the terminal GalNAc from HA fragments - v68:[addCatalystActivity]
[UpdateTracker:9777993] Update Tracker - [Pathway:1632852] Macroautophagy - v68:[addHasEvent]
[UpdateTracker:9778036] Update Tracker - [Reaction:1222655] AhpD reactivates AhpC - v68:[modifyText]
[UpdateTracker:9778502] Update Tracker - [Pathway:168188] Toll Like Receptor TLR6:TLR2 Cascade - v68:[updateContainedPathway, updateContainedRLE]
[UpdateTracker:9778156] Update Tracker - [Pathway:5660724] Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) - v68:[updateContainedRLE]
[UpdateTracker:9778072] Update Tracker - [Pathway:2160456] Phenylketonuria - v68:[updateContainedRLE]
[UpdateTracker:9778547] Update Tracker - [Pathway:5678895] Defective CFTR causes cystic fibrosis - v68:[updateContainedRLE]
[UpdateTracker:9778316] Update Tracker - [Pathway:5579019] Defective FMO3 causes TMAU - v68:[updateContainedRLE]
[UpdateTracker:9778660] Update Tracker - [Pathway:2408522] Selenoamino acid metabolism - v68:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9900249] Update Tracker - [Complex:8869184] PICALM:VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9900202] Update Tracker - [Complex:174222] multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] - v68:[updateContainedComponent]
[UpdateTracker:9778077] Update Tracker - [Pathway:390178] DS ligand not bound to FT receptor - v68:[add_removeHasEvent]
[UpdateTracker:9778055] Update Tracker - [BlackBoxEvent:8854044] Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 - v68:[add_removeOutput]
[UpdateTracker:9778394] Update Tracker - [Pathway:4755583] Defective DOLK causes DOLK-CDG - v68:[updateContainedRLE]
[UpdateTracker:9778221] Update Tracker - [FailedReaction:5625674] Defective SLC22A5 does not cotransport CAR, Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778437] Update Tracker - [Pathway:8878166] Transcriptional regulation by RUNX2 - v68:[updateIndirectRLE]
[UpdateTracker:9778571] Update Tracker - [Pathway:5579029] Metabolic disorders of biological oxidation enzymes - v68:[updateIndirectRLE]
[UpdateTracker:9778137] Update Tracker - [Pathway:948021] Transport to the Golgi and subsequent modification - v68:[updateContainedPathway]
[UpdateTracker:9778205] Update Tracker - [Pathway:5657562] Essential fructosuria - v68:[updateContainedRLE]
[UpdateTracker:9778151] Update Tracker - [Reaction:2559464] TLR6/2 ligand associates with CD14 and CD36 within lipid rafts - v68:[addLiteratureReference]
[UpdateTracker:9778627] Update Tracker - [FailedReaction:5658195] Defective SLC5A5 does not cotransport Na+ with I- from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778102] Update Tracker - [Pathway:212436] Generic Transcription Pathway - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9900104] Update Tracker - [Complex:9027648] ESRs:STRN:ESTG [cytosol] - v68:[addHasComponent, modifyName]
[UpdateTracker:9900081] Update Tracker - [DefinedSet:5691527] Activated FGFR1 mutants and fusions [plasma membrane] - v68:[addDisease]
[UpdateTracker:9900176] Update Tracker - [DefinedSet:9626909] ?2-agonists [extracellular region] - v68:[removeHasMember]
[UpdateTracker:9778387] Update Tracker - [FailedReaction:5661198] Defective SLCO1B3 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte) - v68:[addCatalystActivity]
[UpdateTracker:9778643] Update Tracker - [Pathway:5579024] Defective MAT1A causes MATD - v68:[updateContainedRLE]
[UpdateTracker:9778485] Update Tracker - [Reaction:6807206] USP13 and OTUD3 deubiquitinate PTEN - v68:[add_removeOutput]
[UpdateTracker:9778242] Update Tracker - [Pathway:5619083] Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS) - v68:[updateContainedRLE]
[UpdateTracker:9778492] Update Tracker - [Pathway:451927] Interleukin-2 family signaling - v68:[updateIndirectRLE]
[UpdateTracker:9778435] Update Tracker - [Pathway:6806834] Signaling by MET - v68:[updateIndirectRLE]
[UpdateTracker:9778143] Update Tracker - [Pathway:73884] Base Excision Repair - v68:[updateContainedPathway]
[UpdateTracker:9900084] Update Tracker - [CandidateSet:8869166] SYT dimers [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedMemberOrCandidate]
[UpdateTracker:9777920] Update Tracker - [FailedReaction:5654125] Defective SLC39A4 does not transport Zn2+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778453] Update Tracker - [Pathway:5659898] Intestinal saccharidase deficiencies - v68:[updateContainedRLE]
[UpdateTracker:9900143] Update Tracker - [EntityWithAccessionedSequence:9628816] EREG(60-108) [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778092] Update Tracker - [FailedReaction:5096538] Defective LFNG does not transfer GlcNAc to Pre-NOTCH - v68:[addCatalystActivity]
[UpdateTracker:9778661] Update Tracker - [Pathway:380994] ATF4 activates genes in response to endoplasmic reticulum stress - v68:[updateContainedRLE]
[UpdateTracker:9777913] Update Tracker - [BlackBoxEvent:1791118] Expression of ASNS (Asparagine Synthetase) - v68:[addLiteratureReference, add_removeRegulator, modifyText]
[UpdateTracker:9778391] Update Tracker - [FailedReaction:5660840] Defective SLC6A5 does not cotransport Gly, Cl-, Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9900166] Update Tracker - [Complex:8869145] holoTF:TFRC dimer [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9778555] Update Tracker - [FailedReaction:5655702] Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu - v68:[addCatalystActivity]
[UpdateTracker:9900331] Update Tracker - [Complex:9617320] Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors:CALM1:4xCa2+ [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9900323] Update Tracker - [EntityWithAccessionedSequence:8869133] VAMP4 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778304] Update Tracker - [Pathway:5579032] Defective TBXAS1 causes GHDD - v68:[updateContainedRLE]
[UpdateTracker:9778549] Update Tracker - [Reaction:5576895] SCNAs:SNCBs transport Na+ from extracellular region to cytosol - v68:[addRegulator]
[UpdateTracker:9778557] Update Tracker - [Pathway:5083635] Defective B3GALTL causes PpS - v68:[updateContainedRLE]
[UpdateTracker:9900344] Update Tracker - [Complex:8877010] InlA:Ub-K,p-Y753,Y754-CDH1:Ub-K,p-Y-CTNNB1:CBLL1 dimer:Zn2+ [plasma membrane] - v68:[removeCompartment, updateContainedComponent]
[UpdateTracker:9777887] Update Tracker - [Pathway:5687583] Defective SLC34A2 causes PALM - v68:[updateContainedRLE]
[UpdateTracker:9778580] Update Tracker - [Pathway:375165] NCAM signaling for neurite out-growth - v68:[updateContainedRLE]
[UpdateTracker:9778142] Update Tracker - [Pathway:5660686] Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) - v68:[updateContainedRLE]
[UpdateTracker:9777972] Update Tracker - [Pathway:5619071] Defective SLC22A12 causes renal hypouricemia 1 (RHUC1) - v68:[updateContainedRLE]
[UpdateTracker:9777846] Update Tracker - [Pathway:166058] MyD88:MAL(TIRAP) cascade initiated on plasma membrane - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9900298] Update Tracker - [EntityWithAccessionedSequence:8869079] CD3D [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900215] Update Tracker - [Complex:8871149] PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9778129] Update Tracker - [Pathway:933542] TRAF6 mediated NF-kB activation - v68:[updateContainedRLE]
[UpdateTracker:9778356] Update Tracker - [FailedReaction:5602186] Defective CYP27B1 does not hydroxylate CDL - v68:[addCatalystActivity]
[UpdateTracker:9777980] Update Tracker - [Pathway:2022857] Keratan sulfate degradation - v68:[addHasEvent]
[UpdateTracker:9778342] Update Tracker - [Pathway:5579012] Defective MAOA causes BRUNS - v68:[updateContainedRLE]
[UpdateTracker:9900216] Update Tracker - [Complex:8868620] PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9777839] Update Tracker - [Pathway:5619114] Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) - v68:[updateContainedRLE]
[UpdateTracker:9778683] Update Tracker - [FailedReaction:4686998] Defective MPDU1 does not promote transfer of Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 by ALG12 - v68:[addRegulator]
[UpdateTracker:9778281] Update Tracker - [FailedReaction:5684043] Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix - v68:[addCatalystActivity]
[UpdateTracker:9900063] Update Tracker - [EntityWithAccessionedSequence:8869122] TACR1 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778231] Update Tracker - [FailedReaction:6785565] Defective B3GALTL does not transfer glucose to O-fucosyl-proteins - v68:[addCatalystActivity]
[UpdateTracker:9900310] Update Tracker - [Complex:9607300] Active FLT3:GRB2:SOS1 [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778470] Update Tracker - [Pathway:870392] Mycobacterium tuberculosis biological processes - v68:[addHasEvent]
[UpdateTracker:9777931] Update Tracker - [FailedReaction:5623705] Defective SLC12A3 does not cotransport Cl-, Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778495] Update Tracker - [Pathway:1839124] FGFR1 mutant receptor activation - v68:[updateIndirectRLE]
[UpdateTracker:9900058] Update Tracker - [SimpleEntity:352605] Fe2+ [mitochondrial inner membrane] - v68:[add_removeReferenceEntity]
[UpdateTracker:9900130] Update Tracker - [DefinedSet:418560] cGMP phosphodiesterases [cytosol] - v68:[updateContainedMemberOrCandidate]
[UpdateTracker:9778061] Update Tracker - [BlackBoxEvent:1791107] Expression of DDIT3 (CHOP, GADD153) in response to unfolded protein - v68:[addLiteratureReference, add_removeRegulator, modifyText]
[UpdateTracker:9778457] Update Tracker - [Pathway:4085011] Defective GNE causes sialuria, NK and IBM2 - v68:[updateContainedRLE]
[UpdateTracker:9778652] Update Tracker - [Pathway:9035968] Defective GGT1 in aflatoxin detoxification causes GLUTH - v68:[updateContainedRLE]
[UpdateTracker:9900342] Update Tracker - [DefinedSet:9628820] EGF-like ligands [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900139] Update Tracker - [DefinedSet:1605688] NEU1,4 [lysosomal lumen] - v68:[updateContainedMemberOrCandidate]
[UpdateTracker:9778594] Update Tracker - [FailedReaction:9036041] Defective IDUA does not hydrolyse the unsulfated alpha-L-iduronosidic link in DS - v68:[addCatalystActivity]
[UpdateTracker:9778634] Update Tracker - [Pathway:5083629] Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 - v68:[updateContainedRLE]
[UpdateTracker:9778512] Update Tracker - [Pathway:6807004] Negative regulation of MET activity - v68:[updateContainedRLE]
[UpdateTracker:9778066] Update Tracker - [Pathway:5682113] Defective ABCA1 causes TGD - v68:[updateContainedRLE]
[UpdateTracker:9778436] Update Tracker - [Pathway:3304349] Loss of Function of SMAD2/3 in Cancer - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9900226] Update Tracker - [DefinedSet:8869154] Catecholamine [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778054] Update Tracker - [Pathway:5619104] Defective SLC12A1 causes Bartter syndrome 1 (BS1) - v68:[updateContainedRLE]
[UpdateTracker:9778383] Update Tracker - [Pathway:5083628] Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 - v68:[updateContainedRLE]
[UpdateTracker:9778626] Update Tracker - [Pathway:5619109] Defective SLC6A2 causes orthostatic intolerance (OI) - v68:[updateContainedRLE]
[UpdateTracker:9900172] Update Tracker - [Complex:8869193] ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9900312] Update Tracker - [Complex:377622] Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] - v68:[modifyName]
[UpdateTracker:9777898] Update Tracker - [FailedReaction:5603297] Defective SLC35D1 does not transport UDP-GlcA, UDPGlcNAc - v68:[addCatalystActivity]
[UpdateTracker:9900241] Update Tracker - [Complex:8866534] Ub-misfolded nascent CFTR [cytosol] - v68:[add_removeHasComponent]
[UpdateTracker:9900335] Update Tracker - [Complex:8869203] AGFG1:VAMP7 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777974] Update Tracker - [FailedReaction:5655760] Defective SLC40A1 does not transport Fe3+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778544] Update Tracker - [FailedReaction:9036065] Defective ARSB does not hydrolyse DS - v68:[addCatalystActivity]
[UpdateTracker:9777842] Update Tracker - [Pathway:3304356] SMAD2/3 Phosphorylation Motif Mutants in Cancer - v68:[removeHasEvent, updateContainedRLE]
[UpdateTracker:9778374] Update Tracker - [Reaction:203977] SAR1 Activation And Membrane Binding - v68:[modifyText]
[UpdateTracker:9900136] Update Tracker - [Complex:8942094] PAF1c:WAC:RNF20:RNF40:Ub:UBE2A,B:HIST1H2B [nucleoplasm] - v68:[updateContainedComponent]
[UpdateTracker:9777866] Update Tracker - [Pathway:4724289] Defective ALG6 causes CDG-1c - v68:[updateContainedRLE]
[UpdateTracker:9777850] Update Tracker - [Pathway:2219528] PI3K/AKT Signaling in Cancer - v68:[updateIndirectRLE]
[UpdateTracker:9778100] Update Tracker - [Pathway:211859] Biological oxidations - v68:[updateContainedPathway]
[UpdateTracker:9778543] Update Tracker - [Reaction:8854051] SCF-FBXL18 ubiquitinates FBXL7 - v68:[add_removeInput]
[UpdateTracker:9778282] Update Tracker - [Pathway:5658208] Defective SLC5A2 causes renal glucosuria (GLYS1) - v68:[updateContainedRLE]
[UpdateTracker:9900218] Update Tracker - [Complex:2990903] Nuclear Pore Complex (p-2S,3T-NUP98) [nuclear envelope] - v68:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9778161] Update Tracker - [FailedReaction:3858506] Defective GYS2 does not transfer glucose to growing glycogen chains - v68:[addCatalystActivity]
[UpdateTracker:9900321] Update Tracker - [SimpleEntity:8869062] NAd [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900317] Update Tracker - [EntityWithAccessionedSequence:9628809] AREG(101-187) [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778215] Update Tracker - [FailedReaction:5603108] Defective MAOA does not oxidatively deaminate 5HT - v68:[addCatalystActivity]
[UpdateTracker:9778258] Update Tracker - [FailedReaction:3560789] Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778193] Update Tracker - [Pathway:5658034] HHAT G278V doesn't palmitoylate Hh-Np - v68:[updateContainedRLE]
[UpdateTracker:9778645] Update Tracker - [Pathway:5619041] Defective SLC36A2 causes iminoglycinuria (IG) and hyperglycinuria (HG) - v68:[updateContainedRLE]
[UpdateTracker:9900263] Update Tracker - [Complex:4411397] TCF/LEF:CTNNB1 [nucleoplasm] - v68:[add_removeHasComponent]
[UpdateTracker:9778639] Update Tracker - [FailedReaction:9035956] Defective CYP17A1 does not cleave 17aHPROG - v68:[addCatalystActivity]
[UpdateTracker:9900251] Update Tracker - [Complex:8869191] AP-2:cargo [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9778686] Update Tracker - [FailedReaction:3656258] Defective ST3GAL3 does not transfer SA to keratan - v68:[addCatalystActivity]
[UpdateTracker:9900266] Update Tracker - [EntityWithAccessionedSequence:8869104] PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777910] Update Tracker - [Reaction:5696960] USP49 deubiquitinates H2B - v68:[add_removeOutput]
[UpdateTracker:9900095] Update Tracker - [Complex:6803120] DCD dimer:Zn(2+):anionic phospholipids: [extracellular region] - v68:[removeCompartment]
[UpdateTracker:9778241] Update Tracker - [FailedReaction:9036070] Defective GUSB does not hydrolyse CS/HS precursor - v68:[addCatalystActivity]
[UpdateTracker:9900132] Update Tracker - [SimpleEntity:8856237] GD2 [Golgi membrane] - v68:[addName]
[UpdateTracker:9900283] Update Tracker - [SimpleEntity:113531] Fe2+ [mitochondrial matrix] - v68:[add_removeReferenceEntity, removeName]
[UpdateTracker:9778380] Update Tracker - [Pathway:5679090] Defective ABCG8 causes GBD4 and sitosterolemia - v68:[updateContainedRLE]
[UpdateTracker:9778200] Update Tracker - [FailedReaction:5609939] Defective PGM1 does not isomerise G6P to G1P - v68:[addCatalystActivity]
[UpdateTracker:9778373] Update Tracker - [FailedReaction:4793956] Defective B4GALT1 does not add Gal to N-glycan - v68:[addCatalystActivity]
[UpdateTracker:9778603] Update Tracker - [Reaction:372693] Phosphorylation of BCAR1 by SRC-PTK2 complex - v68:[modifyText]
[UpdateTracker:9777997] Update Tracker - [Pathway:5205647] Mitophagy - v68:[updateIndirectRLE]
[UpdateTracker:9778182] Update Tracker - [FailedReaction:3656254] Defective EXT2 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain - v68:[addCatalystActivity]
[UpdateTracker:9900292] Update Tracker - [Complex:8869170] SYT2 dimer [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778609] Update Tracker - [Reaction:1678920] TLR processing at low pH - v68:[add_removeRegulator]
[UpdateTracker:9778165] Update Tracker - [FailedReaction:5617096] Defective POMGNT1 does not transfer GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 - v68:[addCatalystActivity]
[UpdateTracker:9778355] Update Tracker - [FailedReaction:5605147] Defective CYP1B1 does not 4-hydroxylate EST17b - v68:[addCatalystActivity]
[UpdateTracker:9778345] Update Tracker - [Pathway:168273] Influenza Viral RNA Transcription and Replication - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9900348] Update Tracker - [Complex:8869168] SYT11 dimer [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900157] Update Tracker - [EntityWithAccessionedSequence:5602426] IRAK4 Q293TER [cytosol] - v68:[addName]
[UpdateTracker:9778493] Update Tracker - [Pathway:209397] Formation of the cytosolic BSK 'scaffolding complex' - v68:[addHasEvent]
[UpdateTracker:9900352] Update Tracker - [SimpleEntity:8856228] GD3 [Golgi membrane] - v68:[addName]
[UpdateTracker:9778126] Update Tracker - [Pathway:421984] Heme synthesis - v68:[add_removeHasEvent, add_removeSummation]
[UpdateTracker:9900174] Update Tracker - [Complex:8943053] HLTF:monoUb:K164-PCNA:RAD18:UBE2B:Ub:UBE2N:UBE2V2 [nucleoplasm] - v68:[updateContainedComponent]
[UpdateTracker:9777889] Update Tracker - [Pathway:168176] Toll Like Receptor 5 (TLR5) Cascade - v68:[updateContainedPathway]
[UpdateTracker:9900288] Update Tracker - [Complex:174232] Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] - v68:[add_removeHasComponent]
[UpdateTracker:9778019] Update Tracker - [FailedReaction:5627891] Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778650] Update Tracker - [Pathway:4720475] Defective ALG3 causes CDG-1d - v68:[updateContainedRLE]
[UpdateTracker:9778636] Update Tracker - [FailedReaction:3325540] Defective extracellular BTD does not hydrolyse BCTN - v68:[addCatalystActivity]
[UpdateTracker:9900316] Update Tracker - [EntityWithAccessionedSequence:8869071] AGTR1 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900339] Update Tracker - [EntityWithAccessionedSequence:8869130] VAMP3 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900243] Update Tracker - [Complex:9604751] Active FLT3 [plasma membrane] - v68:[modifyName]
[UpdateTracker:9778328] Update Tracker - [Reaction:5694435] MIA2 and MIA3 load procollagen VII into COPII vesicles - v68:[modifyText]
[UpdateTracker:9778572] Update Tracker - [Reaction:4722133] KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 - v68:[add_removeSummation]
[UpdateTracker:9900301] Update Tracker - [Complex:444796] CaMKII [nucleoplasm] - v68:[add_removeHasComponent]
[UpdateTracker:9778477] Update Tracker - [Pathway:73854] RNA Polymerase I Promoter Clearance - v68:[updateContainedPathway]
[UpdateTracker:9778135] Update Tracker - [FailedReaction:2466710] Defective LRAT does not esterify RBP1:atROL and FACYLs to atREs - v68:[addCatalystActivity]
[UpdateTracker:9777869] Update Tracker - [FailedReaction:3645780] TGFBR2 KD mutants do not phosphorylate TGFBR1 - v68:[modifyText]
[UpdateTracker:9900278] Update Tracker - [Complex:8869163] EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9900066] Update Tracker - [Complex:442735] Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9900051] Update Tracker - [EntityWithAccessionedSequence:5658476] SLC5A7 K499Nfs*13 [plasma membrane] - v68:[addDisease]
[UpdateTracker:9900295] Update Tracker - [EntityWithAccessionedSequence:4754226] JMJD6 [nucleoplasm] - v68:[removeName]
[UpdateTracker:9778056] Update Tracker - [FailedReaction:4719354] Defective DPM3 does not transfer mannose to DOLP to form DOLPman - v68:[addCatalystActivity]
[UpdateTracker:9900214] Update Tracker - [Complex:1889995] B3GAT3:Mn2+ dimer [Golgi membrane] - v68:[modifyName]
[UpdateTracker:9778472] Update Tracker - [FailedReaction:5602242] Defective CYP2U1 does not omega-hydroxylate ARA - v68:[addCatalystActivity]
[UpdateTracker:9778576] Update Tracker - [Pathway:112315] Transmission across Chemical Synapses - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9777963] Update Tracker - [FailedReaction:5601843] Defective CYP17A1 does not 17-hydroxylate PREG - v68:[addCatalystActivity]
[UpdateTracker:9778086] Update Tracker - [Pathway:5619039] Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) - v68:[updateContainedRLE]
[UpdateTracker:9778535] Update Tracker - [Pathway:110331] Cleavage of the damaged purine - v68:[addHasEvent]
[UpdateTracker:9778250] Update Tracker - [Pathway:3595172] Defective CHST3 causes SEDCJD - v68:[updateContainedRLE]
[UpdateTracker:9777942] Update Tracker - [FailedReaction:2318585] Defective HYAL1 does not hydrolyse Chondroitin chains - v68:[addCatalystActivity]
[UpdateTracker:9778222] Update Tracker - [Reaction:5691381] MYSM1 deubiquitinates Histone H2A - v68:[add_removeOutput]
[UpdateTracker:9778013] Update Tracker - [FailedReaction:5579084] Defective AHCY does not hydrolyse AdoHcy - v68:[addCatalystActivity]
[UpdateTracker:9900142] Update Tracker - [Complex:2400008] PI3K Inhibitors:PI3K [cytosol] - v68:[updateContainedComponent]
[UpdateTracker:9900240] Update Tracker - [EntityWithAccessionedSequence:5688015] SFTPB Q45Kfs*8 [endoplasmic reticulum membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777933] Update Tracker - [FailedReaction:9036037] Defective IDUA does not hydrolyse Heparan sulfate chain(1) - v68:[addCatalystActivity]
[UpdateTracker:9777983] Update Tracker - [Pathway:9608287] Defective MUTYH substrate binding - v68:[updateContainedRLE]
[UpdateTracker:9900246] Update Tracker - [EntityWithAccessionedSequence:8869082] CD4 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778628] Update Tracker - [Pathway:3656243] Defective ST3GAL3 causes MCT12 and EIEE15 - v68:[updateContainedRLE]
[UpdateTracker:9778548] Update Tracker - [Pathway:3304351] Signaling by TGF-beta Receptor Complex in Cancer - v68:[updateContainedPathway]
[UpdateTracker:9778354] Update Tracker - [Pathway:3323169] Defects in biotin (Btn) metabolism - v68:[updateIndirectRLE]
[UpdateTracker:9778170] Update Tracker - [Pathway:350054] Notch-HLH transcription pathway - v68:[addHasEvent, updateContainedRLE]
[UpdateTracker:9778445] Update Tracker - [Pathway:9605310] Defective Base Excision Repair Associated with MUTYH - v68:[updateIndirectRLE]
[UpdateTracker:9778196] Update Tracker - [Pathway:5659996] RPIA deficiency: failed conversion of R5P to RU5P - v68:[updateContainedRLE]
[UpdateTracker:9778120] Update Tracker - [FailedReaction:4088338] Defective GNE does not hydrolyse UDP-GlcNAc - v68:[addCatalystActivity]
[UpdateTracker:9900313] Update Tracker - [EntityWithAccessionedSequence:8869092] KIAA0319 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900153] Update Tracker - [CandidateSet:8934444] Activated PRKCA,(PRKCD,PRKCE) [plasma membrane] - v68:[modifyName]
[UpdateTracker:9778134] Update Tracker - [Pathway:4570571] Defective RFT1 causes CDG-1n - v68:[updateContainedRLE]
[UpdateTracker:9778341] Update Tracker - [Pathway:73864] RNA Polymerase I Transcription - v68:[removeHasEvent, updateContainedPathway]
[UpdateTracker:9778395] Update Tracker - [Pathway:5609976] Defective GALK1 causes GALCT2 - v68:[updateContainedRLE]
[UpdateTracker:9777970] Update Tracker - [Pathway:438066] Unblocking of NMDA receptors, glutamate binding and activation - v68:[updateContainedRLE]
[UpdateTracker:9778117] Update Tracker - [Pathway:5660862] Defective SLC7A7 causes lysinuric protein intolerance (LPI) - v68:[updateContainedRLE]
[UpdateTracker:9778390] Update Tracker - [Pathway:433822] NFkB and MAPK activation mediated by TRAF6 - v68:[updateContainedPathway]
[UpdateTracker:9778528] Update Tracker - [Pathway:1971475] A tetrasaccharide linker sequence is required for GAG synthesis - v68:[addHasEvent, updateContainedRLE]
[UpdateTracker:9778136] Update Tracker - [Pathway:5663084] Diseases of carbohydrate metabolism - v68:[updateIndirectRLE]
[UpdateTracker:9900281] Update Tracker - [Complex:8871145] PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9777939] Update Tracker - [FailedReaction:5601976] Defective CYP21A2 does not 21-hydroxylate PROG - v68:[addCatalystActivity]
[UpdateTracker:9778405] Update Tracker - [Reaction:8948832] RNF146 polyubiquitinates PARylated PTEN - v68:[add_removeInput]
[UpdateTracker:9778575] Update Tracker - [Reaction:210404] SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ - v68:[add_removeCatalystActivity]
[UpdateTracker:9778376] Update Tracker - [Pathway:3645790] TGFBR2 Kinase Domain Mutants in Cancer - v68:[removeHasEvent, updateContainedRLE]
[UpdateTracker:9778593] Update Tracker - [Pathway:163685] Integration of energy metabolism - v68:[updateContainedPathway]
[UpdateTracker:9777874] Update Tracker - [Pathway:2990846] SUMOylation - v68:[updateContainedPathway]
[UpdateTracker:9778162] Update Tracker - [FailedReaction:4720497] Defective ALG12 does not add mannose to the N-glycan precursor - v68:[addCatalystActivity]
[UpdateTracker:9778139] Update Tracker - [BlackBoxEvent:432510] CLK is degraded by the 26S proteasome - v68:[addLiteratureReference]
[UpdateTracker:9778400] Update Tracker - [Pathway:5619072] Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M) - v68:[updateContainedRLE]
[UpdateTracker:9777956] Update Tracker - [Pathway:390150] DS ligand bound to FT receptor - v68:[add_removeHasEvent]
[UpdateTracker:9778503] Update Tracker - [Pathway:382551] Transport of small molecules - v68:[updateIndirectRLE]
[UpdateTracker:9778551] Update Tracker - [Reaction:8985929] IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B - v68:[add_removeInput]
[UpdateTracker:9777896] Update Tracker - [FailedReaction:9035966] Defective GGT1 does not hydrolyse GSH - v68:[addCatalystActivity]
[UpdateTracker:9778053] Update Tracker - [Pathway:3858516] Glycogen storage disease type 0 (liver GYS2) - v68:[updateContainedRLE]
[UpdateTracker:9900070] Update Tracker - [Complex:1226015] Ligand-responsive p-6Y-EGFR mutants:GRB2:GAB1 [plasma membrane] - v68:[add_removeHasComponent, modifyName]
[UpdateTracker:9900068] Update Tracker - [Complex:157689] Nuclear Pore Complex (NPC) [nuclear envelope] - v68:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9777885] Update Tracker - [Pathway:353234] Base Excision Repair, AP site formation by depyrimidination - v68:[add_removeHasEvent, modifyText]
[UpdateTracker:9900275] Update Tracker - [Complex:2066711] Dner:Notch1:Dtx1/2/4 [plasma membrane] - v68:[removeCompartment]
[UpdateTracker:9778419] Update Tracker - [Pathway:4420332] Defective B3GALT6 causes EDSP2 and SEMDJL1 - v68:[updateContainedRLE]
[UpdateTracker:9900082] Update Tracker - [EntityWithAccessionedSequence:8869113] SYT1 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778384] Update Tracker - [Pathway:2206282] MPS IIIB - Sanfilippo syndrome B - v68:[updateContainedRLE]
[UpdateTracker:9777834] Update Tracker - [Pathway:9605308] Diseases of Base Excision Repair - v68:[addHasEvent]
[UpdateTracker:9900085] Update Tracker - [EntityWithAccessionedSequence:8869085] CHRM2 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778539] Update Tracker - [Reaction:5637764] Binding of GRB2:GAB1 complex to p-EGFRvIII mutant - v68:[add_removeInput, modifyText]
[UpdateTracker:9778189] Update Tracker - [BlackBoxEvent:168301] Elongation, Polyadenylation and Termination - v68:[addLiteratureReference, add_removeInput, modifyText]
[UpdateTracker:9778310] Update Tracker - [FailedReaction:5633241] Defective ALG14 does not transfer GlcNAc from UDP-GlcNAc to GlcNAcDOLP - v68:[addCatalystActivity]
[UpdateTracker:9900075] Update Tracker - [Complex:8869169] SYT1 dimer [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777990] Update Tracker - [Pathway:3595177] Defective CHSY1 causes TPBS - v68:[updateContainedRLE]
[UpdateTracker:9778148] Update Tracker - [Pathway:453279] Mitotic G1 phase and G1/S transition - v68:[updateContainedPathway]
[UpdateTracker:9778520] Update Tracker - [FailedReaction:2466861] Defective RDH12 does not reduce atRAL to atROL and causes LCA13 - v68:[addCatalystActivity]
[UpdateTracker:9900268] Update Tracker - [Complex:8869173] WNT5A:FZD4:p-DVL2 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9778026] Update Tracker - [FailedReaction:5632804] SLC2A1 tetramer does not transport Glc from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9900338] Update Tracker - [SimpleEntity:917810] Fe2+ [endosome lumen] - v68:[add_removeReferenceEntity, removeName]
[UpdateTracker:9900287] Update Tracker - [Complex:8876263] InlB:MonoUb-K,p-4Y-MET:GRB2-1:p-Y-CBL:CIN85:endophilin:EPS15:HGS:STAM [plasma membrane] - v68:[add_removeEntityOnOtherCell, removeCompartment, updateContainedComponent]
[UpdateTracker:9778015] Update Tracker - [FailedReaction:5656219] Defective SLC4A4 does not cotransport Na+ with 3HCO3- - v68:[addCatalystActivity]
[UpdateTracker:9778029] Update Tracker - [Pathway:388396] GPCR downstream signalling - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778118] Update Tracker - [Pathway:350416] Regulation of non-muscle Myosin II - v68:[add_removeHasEvent]
[UpdateTracker:9778675] Update Tracker - [Pathway:1296065] Inwardly rectifying K+ channels - v68:[updateContainedPathway]
[UpdateTracker:9778684] Update Tracker - [FailedReaction:9036061] Defective GLB1 does not hydrolyse linker chain(2) - v68:[addCatalystActivity]
[UpdateTracker:9778079] Update Tracker - [FailedReaction:5627870] SLC26A4 does not transport I- from cytosol to extracellular region - v68:[addCatalystActivity]
[UpdateTracker:9900272] Update Tracker - [EntityWithAccessionedSequence:9008913] PTPN7 [nucleoplasm] - v68:[modifyEndCoordinate]
[UpdateTracker:9777860] Update Tracker - [Pathway:4549380] Defective ALG1 causes CDG-1k - v68:[updateContainedRLE]
[UpdateTracker:9900353] Update Tracker - [EntityWithAccessionedSequence:157748] NUP35 [nuclear envelope] - v68:[addName]
[UpdateTracker:9778423] Update Tracker - [Pathway:8982491] Glycogen metabolism - v68:[updateContainedPathway]
[UpdateTracker:9778187] Update Tracker - [Pathway:9020702] Interleukin-1 signaling - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9777858] Update Tracker - [FailedReaction:3656267] Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan - v68:[addCatalystActivity]
[UpdateTracker:9900308] Update Tracker - [SimpleEntity:1981115] Fe2+ [endoplasmic reticulum membrane] - v68:[add_removeReferenceEntity, removeName]
[UpdateTracker:9777975] Update Tracker - [Reaction:8876258] CBL monoubiquitinates InlB-bound MET - v68:[add_removeInput]
[UpdateTracker:9778068] Update Tracker - [FailedReaction:5659764] Defective SLC6A2 does not cotransport NAd, Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9777882] Update Tracker - [Pathway:419469] Pyrimidine metabolism: de novo synthesis of UMP - v68:[add_removeHasEvent, modifyText]
[UpdateTracker:9900077] Update Tracker - [EntityWithAccessionedSequence:8869138] p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778439] Update Tracker - [Pathway:5619053] Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP) - v68:[updateContainedRLE]
[UpdateTracker:9900124] Update Tracker - [Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v68:[addName, updateContainedComponent]
[UpdateTracker:9778283] Update Tracker - [FailedReaction:5679145] Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region - v68:[addCatalystActivity]
[UpdateTracker:9778312] Update Tracker - [FailedReaction:3560785] Defective PAPSS2 does not transfer PO4(2-) group from ATP to APS to form PAPS - v68:[addCatalystActivity]
[UpdateTracker:9778125] Update Tracker - [FailedReaction:5602272] Defective CYP4F22 does not 20-hydroxylate TrXA3 - v68:[addCatalystActivity]
[UpdateTracker:9778525] Update Tracker - [FailedReaction:5659899] Defective SI does not hydrolyze maltotriose - v68:[addCatalystActivity]
[UpdateTracker:9778067] Update Tracker - [FailedReaction:5687585] Defective SLC34A2 does not cotransport HPO4(2-), 3Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778174] Update Tracker - [Reaction:1888198] FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3 - v68:[add_removeInput, add_removeOutput]
[UpdateTracker:9778314] Update Tracker - [FailedReaction:5653622] Defective SLC35A3 does not exchange UDP-GlcNAc for UMP - v68:[addCatalystActivity]
[UpdateTracker:9900101] Update Tracker - [SimpleEntity:2318766] Fe2+ [nuclear envelope] - v68:[add_removeReferenceEntity, removeName]
[UpdateTracker:9900340] Update Tracker - [SimpleEntity:1362385] Fe2+ [mitochondrial intermembrane space] - v68:[add_removeReferenceEntity, removeName]
[UpdateTracker:9900265] Update Tracker - [SimpleEntity:1605649] GM3 [plasma membrane] - v68:[addName]
[UpdateTracker:9900294] Update Tracker - [EntityWithAccessionedSequence:8869119] SYT8 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777941] Update Tracker - [Pathway:1483206] Glycerophospholipid biosynthesis - v68:[updateIndirectRLE]
[UpdateTracker:9777944] Update Tracker - [Reaction:8939706] SCF(SKP2) polyubiquitinates RUNX2 - v68:[add_removeInput]
[UpdateTracker:9900193] Update Tracker - [Complex:8875370] InlB:MET [plasma membrane] - v68:[addDisease, add_removeEntityOnOtherCell, add_removeHasComponent, removeCompartment]
[UpdateTracker:9778274] Update Tracker - [Pathway:1638074] Keratan sulfate/keratin metabolism - v68:[updateContainedPathway]
[UpdateTracker:9900168] Update Tracker - [SimpleEntity:29434] SUCCA [cytosol] - v68:[add_removeReferenceEntity]
[UpdateTracker:9778476] Update Tracker - [Reaction:437192] PDPK1 binds PRKCZ - v68:[modifyText]
[UpdateTracker:9900306] Update Tracker - [Complex:372652] CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v68:[addName, updateContainedComponent]
[UpdateTracker:9778337] Update Tracker - [Pathway:433871] TRAF6 mediated induction of proinflammatory cytokines - v68:[updateContainedPathway]
[UpdateTracker:9778464] Update Tracker - [FailedReaction:5602892] Defective GCLC does not ligate L-Glu to L-Cys - v68:[addCatalystActivity]
[UpdateTracker:9900282] Update Tracker - [Complex:5228516] RANBP2:RANGAP1-SUMO1:UBE2I:Nuclear Pore Complex (NPC) [nuclear envelope] - v68:[updateContainedComponent]
[UpdateTracker:9778361] Update Tracker - [Pathway:3214842] HDMs demethylate histones - v68:[updateContainedRLE]
[UpdateTracker:9778023] Update Tracker - [Pathway:5678520] Defective ABCB11 causes PFIC2 and BRIC2 - v68:[updateContainedRLE]
[UpdateTracker:9778260] Update Tracker - [FailedReaction:9036025] Defective MPDU1 does not promote transfer of Man to (GlcNAc)2 (Man)5 (PP-Dol)1 by ALG3 - v68:[addRegulator]
[UpdateTracker:9778398] Update Tracker - [FailedReaction:5602901] Defective GSS does not synthesize GSH - v68:[addCatalystActivity]
[UpdateTracker:9778141] Update Tracker - [Reaction:4085029] NEU2 hydrolyzes Neu5Ac from glycoconjugates - v68:[add_removeInput]
[UpdateTracker:9778481] Update Tracker - [Pathway:71387] Metabolism of carbohydrates - v68:[addHasEvent, updateContainedPathway]
[UpdateTracker:9900254] Update Tracker - [Complex:8868624] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9778230] Update Tracker - [FailedReaction:3274540] Defective G6PC does not hydrolyze glucose 6-phosphate - v68:[addCatalystActivity]
[UpdateTracker:9777895] Update Tracker - [Pathway:5619050] Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) - v68:[updateContainedRLE]
[UpdateTracker:9900206] Update Tracker - [DefinedSet:418562] cAMP PDEs [cytosol] - v68:[updateContainedMemberOrCandidate]
[UpdateTracker:9778253] Update Tracker - [FailedReaction:5603379] TPMT does not transfer CH3 from AdoMet to 6MP - v68:[addCatalystActivity]
[UpdateTracker:9778076] Update Tracker - [Pathway:70171] Glycolysis - v68:[add_removeHasEvent]
[UpdateTracker:9900198] Update Tracker - [Complex:9604756] Active FLT3: GRB2 [plasma membrane] - v68:[modifyName, updateContainedComponent]
[UpdateTracker:9778035] Update Tracker - [FailedReaction:9035988] Defective HLCS does not biotinylate PC:Mn2+ - v68:[addCatalystActivity]
[UpdateTracker:9778681] Update Tracker - [Pathway:204174] Regulation of pyruvate dehydrogenase (PDH) complex - v68:[updateContainedRLE]
[UpdateTracker:9778311] Update Tracker - [FailedReaction:5626270] Defective SLC24A4 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ - v68:[addCatalystActivity]
[UpdateTracker:9900114] Update Tracker - [SimpleEntity:5695963] BH-CoA [mitochondrial matrix] - v68:[addName]
[UpdateTracker:9778409] Update Tracker - [Pathway:3371599] Defective HLCS causes multiple carboxylase deficiency - v68:[updateContainedRLE]
[UpdateTracker:9778216] Update Tracker - [Pathway:6807070] PTEN Regulation - v68:[updateIndirectRLE]
[UpdateTracker:9778155] Update Tracker - [FailedReaction:3781926] Defective PMM2 does not isomerise Man6P to Man1P - v68:[addCatalystActivity]
[UpdateTracker:9900257] Update Tracker - [DefinedSet:179743] ligands of SLC28A3 & 29A1 [cytosol] - v68:[modifyName]
[UpdateTracker:9900052] Update Tracker - [Complex:8869182] STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9900299] Update Tracker - [Complex:9626923] ?2-agonists:ADRA2A,B,C [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778104] Update Tracker - [FailedReaction:4793955] Defective MGAT2 does not transfer GlcNAc to N-glycans - v68:[addCatalystActivity]
[UpdateTracker:9778201] Update Tracker - [Pathway:68875] Mitotic Prophase - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9900267] Update Tracker - [Complex:8869147] TFRC dimer [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778235] Update Tracker - [FailedReaction:4420365] Defective B3GALT6 does not transfer Gal to the tetrasaccharide linker - v68:[addCatalystActivity]
[UpdateTracker:9777954] Update Tracker - [Pathway:111885] Opioid Signalling - v68:[updateContainedPathway]
[UpdateTracker:9778491] Update Tracker - [Pathway:8939211] ESR-mediated signaling - v68:[addHasEvent, modifyText]
[UpdateTracker:9778326] Update Tracker - [FailedReaction:5656438] Defective ALDOB does not cleave Fru 1-P to GA and DHAP - v68:[addCatalystActivity]
[UpdateTracker:9778263] Update Tracker - [Pathway:1296041] Activation of G protein gated Potassium channels - v68:[addHasEvent]
[UpdateTracker:9900078] Update Tracker - [Complex:429434] Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778188] Update Tracker - [Pathway:5619110] Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) - v68:[updateContainedRLE]
[UpdateTracker:9778236] Update Tracker - [Pathway:5619060] Defective CP causes aceruloplasminemia (ACERULOP) - v68:[updateContainedRLE]
[UpdateTracker:9777851] Update Tracker - [FailedReaction:3656257] Defective EXT1 (in EXT1:EXT2) does not transfer GlcA to heparan - v68:[addCatalystActivity]
[UpdateTracker:9778038] Update Tracker - [Pathway:381183] ATF6 (ATF6-alpha) activates chaperone genes - v68:[updateContainedRLE]
[UpdateTracker:9778622] Update Tracker - [Pathway:5083633] Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 - v68:[updateContainedRLE]
[UpdateTracker:9900102] Update Tracker - [SimpleEntity:9008281] estetrol [nucleoplasm] - v68:[add_removeReferenceEntity]
[UpdateTracker:9778417] Update Tracker - [Pathway:5619096] Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1) - v68:[updateContainedRLE]
[UpdateTracker:9778592] Update Tracker - [Pathway:419470] Nucleotide metabolism - v68:[updateContainedPathway]
[UpdateTracker:9778558] Update Tracker - [Pathway:112040] G-protein mediated events - v68:[updateContainedPathway]
[UpdateTracker:9778431] Update Tracker - [Pathway:4755609] Defective DHDDS causes RP59 - v68:[updateContainedRLE]
[UpdateTracker:9778607] Update Tracker - [Pathway:202131] Metabolism of nitric oxide: NOS3 activation and regulation - v68:[addLiteratureReference, add_removeHasEvent, modifyText]
[UpdateTracker:9777877] Update Tracker - [Pathway:110329] Cleavage of the damaged pyrimidine - v68:[addHasEvent]
[UpdateTracker:9778616] Update Tracker - [FailedReaction:3229118] Defective SLC37A4 does not exchange G6P and Pi across the ER membrane - v68:[addCatalystActivity]
[UpdateTracker:9778638] Update Tracker - [Pathway:2262752] Cellular responses to stress - v68:[add_removeHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778658] Update Tracker - [Pathway:983169] Class I MHC mediated antigen processing & presentation - v68:[updateIndirectRLE]
[UpdateTracker:9900120] Update Tracker - [Complex:2033050] Antigen:BCR [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778051] Update Tracker - [FailedReaction:9036012] Defective MAN1B1 does not hydrolyse 1,2-linked mannose (c branch) - v68:[addCatalystActivity]
[UpdateTracker:9900258] Update Tracker - [Complex:2990888] Partially Disassembled NPC [nuclear envelope] - v68:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9778294] Update Tracker - [Pathway:5619087] Defective SLC12A3 causes Gitelman syndrome (GS) - v68:[updateContainedRLE]
[UpdateTracker:9778574] Update Tracker - [Pathway:2534343] Interaction With Cumulus Cells And The Zona Pellucida - v68:[addHasEvent, addLiteratureReference, modifyText]
[UpdateTracker:9778229] Update Tracker - [Reaction:5690790] Histone H2A is dubiquitinated by the PR-DUB complex - v68:[add_removeOutput]
[UpdateTracker:9900346] Update Tracker - [EntityWithAccessionedSequence:9628812] BTC(32-111) [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778133] Update Tracker - [Pathway:110328] Recognition and association of DNA glycosylase with site containing an affected pyrimidine - v68:[addHasEvent]
[UpdateTracker:9778183] Update Tracker - [FailedReaction:5228811] NFKBIA variant is not phosphorylated within IkBA:NF-kappaB - v68:[modifyText]
[UpdateTracker:9900145] Update Tracker - [Complex:164384] G-protein with G(s) alpha:GDP [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9900057] Update Tracker - [CandidateSet:2400011] PI3K mutants,Activator:PI3K [plasma membrane] - v68:[updateContainedMemberOrCandidate]
[UpdateTracker:9778382] Update Tracker - [Pathway:8849469] PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 - v68:[updateContainedRLE]
[UpdateTracker:9777905] Update Tracker - [Pathway:5637810] Constitutive Signaling by EGFRvIII - v68:[updateContainedRLE]
[UpdateTracker:9778278] Update Tracker - [Pathway:3878781] Glycogen storage disease type IV (GBE1) - v68:[updateContainedRLE]
[UpdateTracker:9778632] Update Tracker - [Pathway:392499] Metabolism of proteins - v68:[updateContainedPathway]
[UpdateTracker:9778186] Update Tracker - [Pathway:2206305] MPS IIID - Sanfilippo syndrome D - v68:[updateContainedRLE]
[UpdateTracker:9778168] Update Tracker - [Pathway:5619048] Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1) - v68:[updateContainedRLE]
[UpdateTracker:9778042] Update Tracker - [FailedReaction:3560794] Defective PAPSS2 does not transfer SO4(2-) group to ATP to form APS - v68:[addCatalystActivity]
[UpdateTracker:9778590] Update Tracker - [Pathway:2422406] Innate Immune System - v68:[updateContainedPathway]
[UpdateTracker:9778588] Update Tracker - [FailedReaction:9035976] Defective HEXA does not cleave the terminall GalNAc from small HA fragments - v68:[addCatalystActivity]
[UpdateTracker:9778280] Update Tracker - [Pathway:76009] Platelet Aggregation (Plug Formation) - v68:[updateIndirectRLE]
[UpdateTracker:9778637] Update Tracker - [Pathway:2206291] MPS IIIC - Sanfilippo syndrome C - v68:[updateContainedRLE]
[UpdateTracker:9778553] Update Tracker - [Pathway:5578998] Defective OPLAH causes OPLAHD - v68:[updateContainedRLE]
[UpdateTracker:9777872] Update Tracker - [Pathway:448706] Interleukin-1 processing - v68:[updateContainedRLE]
[UpdateTracker:9778021] Update Tracker - [FailedReaction:9036011] Defective MAN1B1 does not hydrolyse 1,2-linked mannose (b branch) - v68:[addCatalystActivity]
[UpdateTracker:9778154] Update Tracker - [Pathway:5679001] Defective ABCC2 causes DJS - v68:[updateContainedRLE]
[UpdateTracker:9778407] Update Tracker - [Pathway:353377] DNA repair - v68:[updateContainedPathway]
[UpdateTracker:9900196] Update Tracker - [EntityWithAccessionedSequence:157746] NUP58-2 [nuclear envelope] - v68:[addName]
[UpdateTracker:9900279] Update Tracker - [Complex:6783460] TYW5:Fe2+ dimer [cytoplasm] - v68:[updateContainedComponent]
[UpdateTracker:9778624] Update Tracker - [Pathway:5662853] Essential pentosuria - v68:[updateContainedRLE]
[UpdateTracker:9900245] Update Tracker - [EntityWithAccessionedSequence:9628819] HBEGF(63-148) [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778292] Update Tracker - [Reaction:432164] Ca2+ influx into the post-synaptic cell - v68:[addRegulator]
[UpdateTracker:9777923] Update Tracker - [Pathway:3642278] Loss of Function of TGFBR2 in Cancer - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778065] Update Tracker - [Reaction:8875443] USP8 deubiquitinates LRIG1 - v68:[add_removeOutput]
[UpdateTracker:9778353] Update Tracker - [Pathway:5579027] Defective CYP27B1 causes VDDR1B - v68:[updateContainedRLE]
[UpdateTracker:9900259] Update Tracker - [DefinedSet:418547] Phosphodiesterases, dual (cAMP, cGMP) activity [cytosol] - v68:[removeHasMember]
[UpdateTracker:9778656] Update Tracker - [Pathway:166016] Toll Like Receptor 4 (TLR4) Cascade - v68:[updateContainedPathway]
[UpdateTracker:9778043] Update Tracker - [FailedReaction:4551297] Defective ALG11 does not transfer Man to the N-glycan precursor - v68:[addCatalystActivity]
[UpdateTracker:9778121] Update Tracker - [FailedReaction:5625015] Defective SLC1A3 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9900358] Update Tracker - [DefinedSet:6783491] processed tRNA [nucleoplasm] - v68:[modifyName]
[UpdateTracker:9778349] Update Tracker - [FailedReaction:5624211] Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778096] Update Tracker - [Pathway:1638091] Heparan sulfate/heparin (HS-GAG) metabolism - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778599] Update Tracker - [Pathway:69205] G1/S-Specific Transcription - v68:[addLiteratureReference, add_removeHasEvent, modifyText]
[UpdateTracker:9778508] Update Tracker - [Reaction:1889955] B3GAT dimers transfer GlcA to tetrasaccharide linker - v68:[modifyText]
[UpdateTracker:9777959] Update Tracker - [Pathway:433794] TLR4 cascade - v68:[removeHasEvent]
[UpdateTracker:9778673] Update Tracker - [BlackBoxEvent:480301] Expression of EPAS1 (HIF2A) - v68:[removeCatalystActivity]
[UpdateTracker:9900173] Update Tracker - [Complex:9628276] GRIN1:p-Y-GRIN2 NMDA receptors:PSD proteins [plasma membrane] - v68:[addHasComponent]
[UpdateTracker:9778089] Update Tracker - [Pathway:1483191] Synthesis of PC - v68:[updateContainedRLE]
[UpdateTracker:9778109] Update Tracker - [FailedReaction:6785524] Defective C1GALT1C1 does not bind C1GALT1 - v68:[addCatalystActivity]
[UpdateTracker:9900159] Update Tracker - [EntityWithAccessionedSequence:8869135] VAMP7 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777848] Update Tracker - [FailedReaction:5658483] Defective SLC5A7 does not cotransport Cho, Cl-, Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9900291] Update Tracker - [Complex:2033022] IgM [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9777982] Update Tracker - [FailedReaction:4755572] Defective SRD5A3 does not reduce pPNOL to DCHOL - v68:[addCatalystActivity]
[UpdateTracker:9778583] Update Tracker - [FailedReaction:5655733] Defective SLC40A1 does not transport Fe2+ from cytosol to extracellular region - v68:[addCatalystActivity]
[UpdateTracker:9778507] Update Tracker - [FailedReaction:9036729] Defective GAA does not hydrolyze lysosomal glycogen - v68:[addCatalystActivity]
[UpdateTracker:9777928] Update Tracker - [FailedReaction:5682111] Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane - v68:[addCatalystActivity]
[UpdateTracker:9778569] Update Tracker - [Pathway:5579022] Defective GGT1 causes GLUTH - v68:[updateContainedRLE]
[UpdateTracker:9777852] Update Tracker - [Pathway:168255] Influenza Infection - v68:[updateContainedPathway]
[UpdateTracker:9778468] Update Tracker - [FailedReaction:5656459] Defective KHK does not phosphorylate beta-D-fructose - v68:[addCatalystActivity]
[UpdateTracker:9900277] Update Tracker - [Complex:6802672] mutant RAS:GTP:p-RAF:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [plasma membrane] - v68:[addDisease]
[UpdateTracker:9900105] Update Tracker - [Complex:400482] GPR119:monoacylglycerol [plasma membrane] - v68:[modifyName]
[UpdateTracker:9900175] Update Tracker - [EntityWithAccessionedSequence:8869080] CD3G [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900207] Update Tracker - [DefinedSet:913988] PKA catalytic subunits, PKG type I [cytosol] - v68:[add_removeHasMember]
[UpdateTracker:9778040] Update Tracker - [Pathway:400451] Free fatty acids regulate insulin secretion - v68:[addHasEvent, updateContainedPathway]
[UpdateTracker:9778329] Update Tracker - [FailedReaction:5580292] Defective CYP11B1 does not oxidise 11DCORT - v68:[addCatalystActivity]
[UpdateTracker:9778579] Update Tracker - [FailedReaction:9035960] Defective CYP27A1 does not 27-hydroxylate 5?-CHOL3?,7?,24(s)-triol - v68:[addCatalystActivity]
[UpdateTracker:9778184] Update Tracker - [Pathway:5579017] Defective CYP11B1 causes AH4 - v68:[updateContainedRLE]
[UpdateTracker:9900244] Update Tracker - [Complex:8932150] B4GAT1:GYLTL1B [Golgi membrane] - v68:[add_removeHasComponent, modifyName]
[UpdateTracker:9900107] Update Tracker - [Complex:113815] NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] - v68:[updateContainedComponent]
[UpdateTracker:9777847] Update Tracker - [Pathway:5579005] Defective CYP4F22 causes ARCI5 - v68:[updateContainedRLE]
[UpdateTracker:9778090] Update Tracker - [Pathway:5682294] Defective ABCA12 causes ARCI4B - v68:[updateContainedRLE]
[UpdateTracker:9778082] Update Tracker - [Pathway:5619094] Variant SLC6A14 may confer susceptibility towards obesity - v68:[updateContainedRLE]
[UpdateTracker:9778538] Update Tracker - [FailedReaction:5651697] Defective SLC34A2 does not cotransport Pi, 3Na+ - v68:[addCatalystActivity]
[UpdateTracker:9900284] Update Tracker - [Complex:8871142] GGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9777890] Update Tracker - [Pathway:3656237] Defective EXT2 causes exostoses 2 - v68:[updateContainedRLE]
[UpdateTracker:9900039] Update Tracker - [Complex:354113] GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778682] Update Tracker - [Pathway:3229133] Glycogen storage disease type Ib (SLC37A4) - v68:[updateContainedRLE]
[UpdateTracker:9778545] Update Tracker - [Pathway:5619040] Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1) - v68:[updateContainedRLE]
[UpdateTracker:9778546] Update Tracker - [Pathway:381070] IRE1alpha activates chaperones - v68:[updateContainedPathway]
[UpdateTracker:9778653] Update Tracker - [Pathway:5657560] Hereditary fructose intolerance - v68:[updateContainedRLE]
[UpdateTracker:9778447] Update Tracker - [FailedReaction:5623051] Defective RHAG does not transport NH4+ from cytosol to extracellular region (rbc) - v68:[addCatalystActivity]
[UpdateTracker:9778114] Update Tracker - [Pathway:5602358] Diseases associated with the TLR signaling cascade - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778171] Update Tracker - [Pathway:4341670] Defective NEU1 causes sialidosis - v68:[updateContainedRLE]
[UpdateTracker:9900079] Update Tracker - [Complex:5694292] MIA2:MIA3 [endoplasmic reticulum membrane] - v68:[add_removeHasComponent, modifyName]
[UpdateTracker:9778299] Update Tracker - [Reaction:5661114] KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 - v68:[addLiteratureReference, add_removeCatalystActivity, modifyText]
[UpdateTracker:9778449] Update Tracker - [FailedReaction:5601849] Defective CYP19A1 does not convert ANDST to E1 - v68:[addCatalystActivity]
[UpdateTracker:9778128] Update Tracker - [Pathway:5609977] Defective GALE causes EDG - v68:[updateContainedRLE]
[UpdateTracker:9778665] Update Tracker - [Pathway:5619043] Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) - v68:[updateContainedRLE]
[UpdateTracker:9778321] Update Tracker - [FailedReaction:5659674] Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778489] Update Tracker - [FailedReaction:5679031] Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region - v68:[addCatalystActivity]
[UpdateTracker:9778490] Update Tracker - [Pathway:1989781] PPARA activates gene expression - v68:[updateContainedRLE]
[UpdateTracker:9778336] Update Tracker - [FailedReaction:9036289] Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan - v68:[addCatalystActivity]
[UpdateTracker:9900303] Update Tracker - [Complex:372688] BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] - v68:[addName, updateContainedComponent]
[UpdateTracker:9778225] Update Tracker - [FailedReaction:5610036] Defective GALE does not epimerise UDP-Gal to UDP-Glc - v68:[addCatalystActivity]
[UpdateTracker:9778144] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v68:[updateContainedPathway]
[UpdateTracker:9900220] Update Tracker - [Complex:198299] Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] - v68:[add_removeHasComponent]
[UpdateTracker:9900092] Update Tracker - [Complex:8866846] ub-CFTR F508del:ERAD complex [endoplasmic reticulum membrane] - v68:[add_removeHasComponent]
[UpdateTracker:9778659] Update Tracker - [Pathway:4720489] Defective ALG12 causes CDG-1g - v68:[updateContainedRLE]
[UpdateTracker:9778339] Update Tracker - [Pathway:5619088] Defective SLC39A4 causes acrodermatitis enteropathica, zinc-deficiency type (AEZ) - v68:[updateContainedRLE]
[UpdateTracker:9778062] Update Tracker - [FailedReaction:3282876] Defective G6PC3 does not hydrolyze glucose 6-phosphate - v68:[addCatalystActivity]
[UpdateTracker:9778455] Update Tracker - [Pathway:381042] PERK regulates gene expression - v68:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9777916] Update Tracker - [FailedReaction:5625123] Defective SLC20A2 does not cotransport Pi, Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778325] Update Tracker - [Pathway:73927] Depurination - v68:[updateContainedPathway]
[UpdateTracker:9778199] Update Tracker - [FailedReaction:5615556] Defective POMT2 does not transfer Man from Dol-P-Man to DAG1 - v68:[addCatalystActivity]
[UpdateTracker:9900189] Update Tracker - [Complex:8876983] InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1:CBLL1 dimer:Zn2+ [plasma membrane] - v68:[removeCompartment, updateContainedComponent]
[UpdateTracker:9778610] Update Tracker - [Pathway:114604] GPVI-mediated activation cascade - v68:[updateContainedRLE]
[UpdateTracker:9778259] Update Tracker - [Pathway:210500] Glutamate Neurotransmitter Release Cycle - v68:[updateContainedRLE]
[UpdateTracker:9900192] Update Tracker - [Complex:8876251] InlB:MonoUb-K,p-4Y-MET dimer:GRB2-1:p-Y-CBL:CIN85:endophilin [plasma membrane] - v68:[add_removeEntityOnOtherCell, removeCompartment, updateContainedComponent]
[UpdateTracker:9900271] Update Tracker - [EntityWithAccessionedSequence:8857584] p-Y565-HIF1A [cytosol] - v68:[modifyName, removeHasModifiedResidue]
[UpdateTracker:9778358] Update Tracker - [Pathway:5260271] Diseases of Immune System - v68:[updateContainedPathway]
[UpdateTracker:9778662] Update Tracker - [FailedReaction:9035954] Defective CYP17A1 does not 17-hydroxylate P4 - v68:[addCatalystActivity]
[UpdateTracker:9900155] Update Tracker - [EntityWithAccessionedSequence:1222708] lpdC [cytosol] - v68:[modifyName]
[UpdateTracker:9777924] Update Tracker - [Pathway:5656364] Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) - v68:[updateContainedRLE]
[UpdateTracker:9778364] Update Tracker - [Pathway:8854050] FBXL7 down-regulates AURKA during mitotic entry and in early mitosis - v68:[updateContainedRLE]
[UpdateTracker:9778412] Update Tracker - [Pathway:73857] RNA Polymerase II Transcription - v68:[updateContainedPathway]
[UpdateTracker:9900106] Update Tracker - [DefinedSet:179737] ligands of SLC28A3 & 29A1 [extracellular region] - v68:[modifyName]
[UpdateTracker:9900309] Update Tracker - [EntityWithAccessionedSequence:2685598] p-T1381,T1393-Mekk1 [cytosol] - v68:[modifyName]
[UpdateTracker:9900179] Update Tracker - [Complex:8871137] GGC-RAB5:GDP [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedComponent]
[UpdateTracker:9777853] Update Tracker - [Pathway:354194] GRB2:SOS provides linkage to MAPK signaling for Integrins - v68:[updateContainedRLE]
[UpdateTracker:9778401] Update Tracker - [FailedReaction:5602885] Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL - v68:[addCatalystActivity]
[UpdateTracker:9778247] Update Tracker - [FailedReaction:3304394] Activated TGFBR1 cannot phosphorylate SMAD2 and SMAD3 Phosphorylation Motif Mutants - v68:[modifyText]
[UpdateTracker:9900304] Update Tracker - [EntityWithAccessionedSequence:2471697] RDH12 Y226C [photoreceptor inner segment membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777945] Update Tracker - [Pathway:5619047] Defective SLC2A9 causes hypouricemia renal 2 (RHUC2) - v68:[updateContainedRLE]
[UpdateTracker:9777951] Update Tracker - [BlackBoxEvent:8866553] misfolded CFTR is degraded by the 26S proteasome - v68:[add_removeOutput]
[UpdateTracker:9777844] Update Tracker - [Pathway:983170] Antigen Presentation: Folding, assembly and peptide loading of class I MHC - v68:[updateContainedRLE]
[UpdateTracker:9778451] Update Tracker - [Reaction:9011543] DCA binds PDK2 - v68:[modifyText]
[UpdateTracker:9778306] Update Tracker - [Pathway:5619085] Defective SLC26A3 causes congenital secretory chloride diarrhea 1 (DIAR1) - v68:[updateContainedRLE]
[UpdateTracker:9900190] Update Tracker - [Complex:3304396] TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 Phosphorylation Motif Mutants [early endosome membrane] - v68:[modifyName]
[UpdateTracker:9900355] Update Tracker - [Complex:8876253] InlB:MonoUb-K,p-4Y-MET dimer:GRB2-1:p-Y-CBL [plasma membrane] - v68:[add_removeEntityOnOtherCell, removeCompartment, updateContainedComponent]
[UpdateTracker:9900300] Update Tracker - [Complex:1222635] lpdC dimer [cytosol] - v68:[modifyName]
[UpdateTracker:9778297] Update Tracker - [Pathway:4549349] Defective ALG2 causes CDG-1i - v68:[updateContainedRLE]
[UpdateTracker:9778352] Update Tracker - [Reaction:372519] AcCho is hydrolyzed to Cho and acetate by ACHE - v68:[addRegulator]
[UpdateTracker:9777965] Update Tracker - [FailedReaction:5625210] Defective SLC22A12 does not exchange extracellular urate for cytosolic LACT - v68:[addCatalystActivity]
[UpdateTracker:9778671] Update Tracker - [Pathway:451524] MAPK activation in TLR cascade - v68:[updateContainedPathway]
[UpdateTracker:9778667] Update Tracker - [Pathway:5602498] MyD88 deficiency (TLR2/4) - v68:[updateContainedRLE]
[UpdateTracker:9778049] Update Tracker - [Pathway:3247509] Chromatin modifying enzymes - v68:[modifyText, updateIndirectRLE]
[UpdateTracker:9778057] Update Tracker - [Pathway:112314] Neurotransmitter receptors and postsynaptic signal transmission - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778362] Update Tracker - [FailedReaction:9036056] Defective HGSNAT does not acetylate Heparan sulfate chain(3) - v68:[addCatalystActivity]
[UpdateTracker:9900165] Update Tracker - [SimpleEntity:879558] AA [cytosol] - v68:[addName]
[UpdateTracker:9777991] Update Tracker - [Reaction:1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) - v68:[addLiteratureReference, modifyText]
[UpdateTracker:9778651] Update Tracker - [FailedReaction:6785245] Defective CYP11B2 does not oxidise CORST - v68:[addCatalystActivity]
[UpdateTracker:9777886] Update Tracker - [Pathway:5659735] Defective SLC6A19 causes Hartnup disorder (HND) - v68:[updateContainedRLE]
[UpdateTracker:9777969] Update Tracker - [FailedReaction:5602004] Defective CYP24A1 does not 24-hydroxylate CALTOL - v68:[addCatalystActivity]
[UpdateTracker:9900115] Update Tracker - [Complex:8877012] InlA:Ub-K,p-Y753,Y754-CDH1:Ub-K,p-Y-CTNNB1 [plasma membrane] - v68:[addHasComponent, removeCompartment, updateContainedComponent]
[UpdateTracker:9777925] Update Tracker - [Pathway:198725] Nuclear Events (kinase and transcription factor activation) - v68:[updateIndirectRLE]
[UpdateTracker:9778562] Update Tracker - [FailedReaction:5658001] Defective LCT does not hydrolyze Lac - v68:[addCatalystActivity]
[UpdateTracker:9778020] Update Tracker - [Pathway:4085023] Defective GFPT1 causes CMSTA1 - v68:[updateContainedRLE]
[UpdateTracker:9900177] Update Tracker - [CandidateSet:8871134] GGC-RAB5 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778202] Update Tracker - [Pathway:177929] Signaling by EGFR - v68:[updateIndirectRLE]
[UpdateTracker:9777909] Update Tracker - [FailedReaction:4724330] Defective ALG8 does not add glucose to the N-glycan precursor - v68:[addCatalystActivity]
[UpdateTracker:9900280] Update Tracker - [SimpleEntity:8868704] PI4P [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9900111] Update Tracker - [DefinedSet:8869161] AP-2 cargo [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment, updateContainedMemberOrCandidate]
[UpdateTracker:9778649] Update Tracker - [Pathway:4720454] Defective ALG9 causes CDG-1l - v68:[updateContainedRLE]
[UpdateTracker:9777864] Update Tracker - [Reaction:8866856] RNF5 and RNF185 ubiquitinate CFTR F508del - v68:[add_removeInput]
[UpdateTracker:9778287] Update Tracker - [Pathway:5619063] Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS) - v68:[updateContainedRLE]
[UpdateTracker:9777996] Update Tracker - [Reaction:2993898] VRK1/VRK2 phosphorylate BANF1 - v68:[modifyText]
[UpdateTracker:9778600] Update Tracker - [FailedReaction:5602984] Defective GGT1 does not hydrolyse glutamate from AFXBO-SG, AFNBO-SG - v68:[addCatalystActivity]
[UpdateTracker:9778509] Update Tracker - [Pathway:5619073] Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) - v68:[updateContainedRLE]
[UpdateTracker:9900217] Update Tracker - [EntityWithAccessionedSequence:2471928] RBP4 G75D [extracellular region] - v68:[add_removeCompartment]
[UpdateTracker:9778017] Update Tracker - [Reaction:354087] Recruitment of GRB2 to p-PTK2 - v68:[modifyText]
[UpdateTracker:9778370] Update Tracker - [Pathway:5683371] Defective ABCB6 causes MCOPCB7 - v68:[updateContainedRLE]
[UpdateTracker:9778585] Update Tracker - [Pathway:1839117] Signaling by cytosolic FGFR1 fusion mutants - v68:[updateContainedRLE]
[UpdateTracker:9778223] Update Tracker - [Pathway:110526] Insulin receptor mediated signaling - v68:[add_removeHasEvent]
[UpdateTracker:9778169] Update Tracker - [FailedReaction:4720473] Defective ALG3 does not add mannose to the N-glycan precursor - v68:[addCatalystActivity]
[UpdateTracker:9900093] Update Tracker - [Complex:2033055] Antigen:p-BCR [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9900156] Update Tracker - [Complex:8876999] InlA:p-Y753,Y754-CDH1:p-Y-CTNNB1 [plasma membrane] - v68:[removeCompartment]
[UpdateTracker:9778429] Update Tracker - [Pathway:5205685] PINK1-PRKN Mediated Mitophagy - v68:[updateContainedRLE]
[UpdateTracker:9777894] Update Tracker - [FailedReaction:4793949] Defective MAN1B1 does not hydrolyse 1,2-linked mannose (a branch) - v68:[addCatalystActivity]
[UpdateTracker:9777897] Update Tracker - [Pathway:5633231] Defective ALG14 causes ALG14-CMS - v68:[updateContainedRLE]
[UpdateTracker:9778428] Update Tracker - [Pathway:4043911] Defective PMM2 causes PMM2-CDG - v68:[updateContainedRLE]
[UpdateTracker:9777947] Update Tracker - [FailedReaction:2466828] Defective RBP4 does not bind atROL - v68:[add_removeInput]
[UpdateTracker:9778446] Update Tracker - [Pathway:73928] Depyrimidination - v68:[updateContainedPathway]
[UpdateTracker:9900158] Update Tracker - [Complex:168130] NFkB inhibitor:NFkB complex [cytosol] - v68:[addLiteratureReference, addName, updateContainedComponent]
[UpdateTracker:9777981] Update Tracker - [FailedReaction:5624256] Defective SLC17A8 does not exchange cytosolic L-Glu for synaptic vesicle H+ - v68:[addCatalystActivity]
[UpdateTracker:9778676] Update Tracker - [Pathway:3560796] Defective PAPSS2 causes SEMD-PA - v68:[updateContainedRLE]
[UpdateTracker:9900211] Update Tracker - [Complex:354168] GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] - v68:[modifyName, updateContainedComponent]
[UpdateTracker:9778059] Update Tracker - [Pathway:73772] RNA Polymerase I Promoter Escape - v68:[addHasEvent, modifyText]
[UpdateTracker:9777837] Update Tracker - [Reaction:1222690] DlaT reactivates AhpD - v68:[modifyText]
[UpdateTracker:9778178] Update Tracker - [Pathway:8948747] Regulation of PTEN localization - v68:[updateContainedRLE]
[UpdateTracker:9778534] Update Tracker - [Pathway:5578997] Defective AHCY causes HMAHCHD - v68:[updateContainedRLE]
[UpdateTracker:9778332] Update Tracker - [FailedReaction:4724291] Defective ALG6 does not add glucose to the N-glycan precursor - v68:[addCatalystActivity]
[UpdateTracker:9900350] Update Tracker - [EntityWithAccessionedSequence:8869106] SCARB2 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778672] Update Tracker - [Pathway:5687613] Diseases associated with surfactant metabolism - v68:[updateIndirectRLE]
[UpdateTracker:9777977] Update Tracker - [FailedReaction:4717406] Defective DPM1 does not transfer mannose to DOLP to form DOLPman - v68:[addCatalystActivity]
[UpdateTracker:9778461] Update Tracker - [Pathway:5579002] Defective UGT1A1 causes hyperbilirubinemia - v68:[updateContainedRLE]
[UpdateTracker:9778157] Update Tracker - [Pathway:354192] Integrin signaling - v68:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9900252] Update Tracker - [Complex:212451] CSL NICD coactivator complex [nucleoplasm] - v68:[add_removeHasComponent]
[UpdateTracker:9777992] Update Tracker - [Pathway:1266738] Developmental Biology - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778640] Update Tracker - [Pathway:3656244] Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) - v68:[updateContainedRLE]
[UpdateTracker:9900290] Update Tracker - [Complex:2033053] p-BCR [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778209] Update Tracker - [Pathway:5619102] SLC transporter disorders - v68:[updateIndirectRLE]
[UpdateTracker:9778537] Update Tracker - [Pathway:204005] COPII-mediated vesicle transport - v68:[updateContainedRLE]
[UpdateTracker:9778647] Update Tracker - [Pathway:5688399] Defective ABCA3 causes SMDP3 - v68:[updateContainedRLE]
[UpdateTracker:9777855] Update Tracker - [FailedReaction:5660706] Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol - v68:[addCatalystActivity]
[UpdateTracker:9778516] Update Tracker - [Pathway:5619045] Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) - v68:[updateContainedRLE]
[UpdateTracker:9778469] Update Tracker - [Pathway:381038] XBP1(S) activates chaperone genes - v68:[removeHasEvent]
[UpdateTracker:9900242] Update Tracker - [DefinedSet:8869153] DAB2,LDLRAP1 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778393] Update Tracker - [FailedReaction:5678749] Defective ABCB4 does not transport PC from plasma membrane to extracellular region - v68:[addCatalystActivity]
[UpdateTracker:9778269] Update Tracker - [Pathway:168179] Toll Like Receptor TLR1:TLR2 Cascade - v68:[updateContainedPathway]
[UpdateTracker:9778018] Update Tracker - [Reaction:168950] TLR6:TLR2 is recruited to ligand:CD14:CD36 - v68:[addLiteratureReference]
[UpdateTracker:9778009] Update Tracker - [BlackBoxEvent:1791173] Expression of ATF3 - v68:[addLiteratureReference, add_removeRegulator, modifyText]
[UpdateTracker:9778264] Update Tracker - [Pathway:3359471] Defective MMAB causes MMA, cblB type - v68:[updateContainedRLE]
[UpdateTracker:9778438] Update Tracker - [Pathway:2474795] Diseases associated with visual transduction - v68:[updateIndirectRLE]
[UpdateTracker:9778219] Update Tracker - [Pathway:8848021] Signaling by PTK6 - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778350] Update Tracker - [FailedReaction:5096537] Defective GALNT3 does not transfer GalNAc to mucins - v68:[addCatalystActivity]
[UpdateTracker:9778027] Update Tracker - [FailedReaction:5662851] Defective DCXR does not reduce L-xylulose to xylitol - v68:[addCatalystActivity]
[UpdateTracker:9778103] Update Tracker - [Pathway:3781860] Diseases associated with N-glycosylation of proteins - v68:[updateIndirectRLE]
[UpdateTracker:9778655] Update Tracker - [Reaction:975449] GABRR pentamers:GABA transports extracellular Cl- to cytosol - v68:[modifyText]
[UpdateTracker:9778623] Update Tracker - [FailedReaction:5603087] Defective MAT1A does not transfer Ado from ATP to L-Met - v68:[addCatalystActivity]
[UpdateTracker:9778002] Update Tracker - [Pathway:422475] Axon guidance - v68:[updateIndirectRLE]
[UpdateTracker:9778584] Update Tracker - [Pathway:5658471] Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) - v68:[updateContainedRLE]
[UpdateTracker:9900253] Update Tracker - [Complex:174140] Cdc2:Cyclin A:MCC:APC/C complex [cytosol] - v68:[updateContainedComponent]
[UpdateTracker:9777917] Update Tracker - [Reaction:8848829] CBL autoubiquitinates - v68:[add_removeInput]
[UpdateTracker:9900134] Update Tracker - [EntityWithAccessionedSequence:2466821] ABCA4 G863A [photoreceptor disc membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778211] Update Tracker - [Reaction:8857583] LINC01139 promotes phosphorylation of HIF1A by PTK6 - v68:[modifyText]
[UpdateTracker:9778595] Update Tracker - [FailedReaction:3595178] Defective CHSY1 does not transfer GlcA to chondroitin - v68:[addCatalystActivity]
[UpdateTracker:9778529] Update Tracker - [Pathway:879518] Transport of organic anions - v68:[addHasEvent]
[UpdateTracker:9778365] Update Tracker - [FailedReaction:5659989] Defective TALDO1 does not transform SH7P, GA3P to Fru(6)P, E4P - v68:[addCatalystActivity]
[UpdateTracker:9777836] Update Tracker - [Pathway:5609978] Defective GALT can cause GALCT - v68:[updateContainedRLE]
[UpdateTracker:9778397] Update Tracker - [FailedReaction:5602147] Defective CYP2R1 does not 25-hydroxylate vitamin D - v68:[addCatalystActivity]
[UpdateTracker:9778159] Update Tracker - [FailedReaction:5659926] Defective SI does not hydrolyze Suc - v68:[addCatalystActivity]
[UpdateTracker:9778591] Update Tracker - [Pathway:5619092] Defective SLC9A6 causes X-linked, syndromic mental retardation,, Christianson type (MRXSCH) - v68:[updateContainedRLE]
[UpdateTracker:9778227] Update Tracker - [FailedReaction:2466802] Defective ABCA4 does not transport NRPE from disc membranes - v68:[addCatalystActivity]
[UpdateTracker:9778298] Update Tracker - [Pathway:1660598] Metabolism - v68:[updateContainedPathway]
[UpdateTracker:9777989] Update Tracker - [Pathway:5660883] Defective SLC7A9 causes cystinuria (CSNU) - v68:[updateContainedRLE]
[UpdateTracker:9778069] Update Tracker - [Reaction:198731] ERK1/2 activates ELK1 - v68:[modifyText]
[UpdateTracker:9778389] Update Tracker - [Reaction:8866546] RNF5 and RNF185 ubiquitinate misfolded CFTR - v68:[add_removeInput]
[UpdateTracker:9778641] Update Tracker - [FailedReaction:9036008] Defective MAN1B1 does not hydrolyse a second 1,2-linked mannose (a branch) - v68:[addCatalystActivity]
[UpdateTracker:9778001] Update Tracker - [FailedReaction:9036104] Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BMG - v68:[addCatalystActivity]
[UpdateTracker:9777857] Update Tracker - [Pathway:2453864] Retinoid cycle disease events - v68:[updateContainedRLE]
[UpdateTracker:9778363] Update Tracker - [Pathway:5688426] Deubiquitination - v68:[updateIndirectRLE]
[UpdateTracker:9900194] Update Tracker - [Complex:437184] PDPK1:PIP3:p-T410-PRKCZ [plasma membrane] - v68:[modifyName]
[UpdateTracker:9778343] Update Tracker - [Reaction:8875371] InlB binds MET - v68:[add_removeInput]
[UpdateTracker:9778218] Update Tracker - [Pathway:168164] Toll Like Receptor 3 (TLR3) Cascade - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9900330] Update Tracker - [SimpleEntity:113671] 2OG [nucleoplasm] - v68:[add_removeReferenceEntity]
[UpdateTracker:9778116] Update Tracker - [Pathway:2206308] MPS IV - Morquio syndrome B - v68:[updateContainedRLE]
[UpdateTracker:9778163] Update Tracker - [Pathway:5619101] Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) - v68:[updateContainedRLE]
[UpdateTracker:9778418] Update Tracker - [Pathway:1296059] G protein gated Potassium channels - v68:[updateContainedPathway]
[UpdateTracker:9900262] Update Tracker - [Complex:9614256] Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778486] Update Tracker - [Pathway:3656248] Defective HEXB causes GM2G2 - v68:[updateContainedRLE]
[UpdateTracker:9900327] Update Tracker - [EntityWithAccessionedSequence:60537] NTHL1 [nucleoplasm] - v68:[modifyStartCoordinate]
[UpdateTracker:9778602] Update Tracker - [Pathway:5679096] Defective ABCG5 causes sitosterolemia - v68:[updateContainedRLE]
[UpdateTracker:9900056] Update Tracker - [EntityWithAccessionedSequence:2471748] RDH12 Ala269Glyfs*2 [photoreceptor inner segment membrane] - v68:[add_removeCompartment]
[UpdateTracker:9778160] Update Tracker - [Pathway:5173105] O-linked glycosylation - v68:[addHasEvent, updateContainedRLE]
[UpdateTracker:9900305] Update Tracker - [Complex:2033035] B Cell Receptor [plasma membrane] - v68:[updateContainedComponent]
[UpdateTracker:9778617] Update Tracker - [Pathway:977443] GABA receptor activation - v68:[add_removeHasEvent, updateContainedPathway, updateContainedRLE]
[UpdateTracker:9900289] Update Tracker - [EntityWithAccessionedSequence:8869077] AVPR2 [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]
[UpdateTracker:9777949] Update Tracker - [Pathway:112310] Neurotransmitter release cycle - v68:[updateIndirectRLE]
[UpdateTracker:9777870] Update Tracker - [Pathway:5694530] Cargo concentration in the ER - v68:[modifyText, updateContainedRLE]
[UpdateTracker:9900083] Update Tracker - [SimpleEntity:8869060] Fe3+ [clathrin-coated endocytic vesicle membrane] - v68:[add_removeCompartment]

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