Reactome | 81 on 2022-06-09

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81 on 2022-06-09 Show undefined attributes

dbId	9774624
displayName	81 on 2022-06-09
modified	[InstanceEdit:9982963] Weiser, Joel, 2026-02-20
releaseDate	2022-06-09
releaseNumber	81
schemaClass	Release

Referrals

(release)

[UpdateTracker:9774721] Update Tracker - [Pathway:5362517] Signaling by Retinoic Acid - v81:[addHasEvent]
[UpdateTracker:9904229] Update Tracker - [Complex:77470] ATAC B Complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904286] Update Tracker - [Complex:3222583] Group I Metabotropic glutamate receptors:Glu [plasma membrane] - v81:[add_removeHasComponent]
[UpdateTracker:9774643] Update Tracker - [Pathway:400508] Incretin synthesis, secretion, and inactivation - v81:[updateContainedPathway]
[UpdateTracker:9774743] Update Tracker - [Pathway:9694548] Maturation of spike protein - v81:[addHasEvent, updateContainedRLE]
[UpdateTracker:9774810] Update Tracker - [Pathway:2672351] Stimuli-sensing channels - v81:[addHasEvent, updateContainedPathway]
[UpdateTracker:9904248] Update Tracker - [SimpleEntity:6787326] dR1P [cytosol] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9904204] Update Tracker - [Complex:113724] Elongation complex prior to separation [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904325] Update Tracker - [EntityWithAccessionedSequence:71991] CPSF2 [nucleoplasm] - v81:[addName]
[UpdateTracker:9774832] Update Tracker - [Pathway:140179] Amine Oxidase reactions - v81:[updateContainedPathway]
[UpdateTracker:9774639] Update Tracker - [Pathway:72172] mRNA Splicing - v81:[updateIndirectRLE]
[UpdateTracker:9774778] Update Tracker - [Pathway:166058] MyD88:MAL(TIRAP) cascade initiated on plasma membrane - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904237] Update Tracker - [Complex:167199] P-TEFb(Cyclin T1:Cdk9)-containing elongation complex with separated and uncleaved transcript [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904305] Update Tracker - [DefinedSet:6803738] GlcNAc-6-P, GlcNGc-6-P [cytosol] - v81:[add_removeHasMember]
[UpdateTracker:9904344] Update Tracker - [Complex:9713634] m7GpppA-capped SARS-CoV-2 genomic RNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904338] Update Tracker - [SimpleEntity:744227] UDP-D-glucose(2-) [Golgi lumen] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9904278] Update Tracker - [EntityWithAccessionedSequence:71887] SNU13 [nucleoplasm] - v81:[addName]
[UpdateTracker:9904249] Update Tracker - [SimpleEntity:29548] G1P [cytosol] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9904290] Update Tracker - [EntityWithAccessionedSequence:9694791] complex N-glycan-PALM-Spike S2 Fragment [virion membrane] - v81:[addHasModifiedResidue, modifyEndCoordinate, modifyStartCoordinate]
[UpdateTracker:9774836] Update Tracker - [Pathway:3322077] Glycogen synthesis - v81:[removeHasEvent, updateContainedRLE]
[UpdateTracker:9774647] Update Tracker - [Pathway:162582] Signal Transduction - v81:[updateContainedPathway]
[UpdateTracker:9774825] Update Tracker - [Reaction:9638127] PGM1:Mg2+ isomerises G6P to G1P - v81:[add_removeLiteratureReference, modifyText]
[UpdateTracker:9904309] Update Tracker - [Complex:9694458] SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9774843] Update Tracker - [BlackBoxEvent:2186780] Degradation of Ub-SMAD7 - v81:[modifyText]
[UpdateTracker:9904227] Update Tracker - [Complex:9694717] nsp7:nsp8:nsp12:nsp14:nsp10:nsp13 [cytosol] - v81:[updateContainedComponent]
[UpdateTracker:9904298] Update Tracker - [Complex:72074] Spliceosomal Intermediate C Complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904242] Update Tracker - [Complex:9694302] RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9774785] Update Tracker - [Pathway:2173795] Downregulation of SMAD2/3:SMAD4 transcriptional activity - v81:[addHasEvent, updateContainedRLE]
[UpdateTracker:9904267] Update Tracker - [EntityWithAccessionedSequence:6806143] GPI-PLAUR [specific granule membrane] - v81:[addHasModifiedResidue, modifyName]
[UpdateTracker:9774649] Update Tracker - [Pathway:390666] Serotonin receptors - v81:[addHasEvent]
[UpdateTracker:9774718] Update Tracker - [Pathway:109606] Intrinsic Pathway for Apoptosis - v81:[updateContainedPathway]
[UpdateTracker:9774811] Update Tracker - [Pathway:5603029] IkBA variant leads to EDA-ID - v81:[updateContainedRLE]
[UpdateTracker:9904209] Update Tracker - [EntityWithAccessionedSequence:6808777] GPI-FOLR1 [Golgi membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9904289] Update Tracker - [Complex:8867145] CEACAM1,3,5,6:opa proteins [plasma membrane] - v81:[updateContainedComponent]
[UpdateTracker:9774819] Update Tracker - [Pathway:141333] Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB - v81:[addHasEvent]
[UpdateTracker:9904206] Update Tracker - [EntityWithAccessionedSequence:169104] CPSF4 [nucleoplasm] - v81:[modifyName]
[UpdateTracker:9774808] Update Tracker - [Pathway:983695] Antigen activates B Cell Receptor (BCR) leading to generation of second messengers - v81:[addHasEvent]
[UpdateTracker:9774683] Update Tracker - [Pathway:445989] TAK1-dependent IKK and NF-kappa-B activation - v81:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9774732] Update Tracker - [Reaction:168166] NF-kappa-B complex is transported from cytosol to nucleus - v81:[modifyText]
[UpdateTracker:9774681] Update Tracker - [Pathway:5684264] MAP3K8 (TPL2)-dependent MAPK1/3 activation - v81:[updateContainedRLE]
[UpdateTracker:9774638] Update Tracker - [Pathway:5576891] Cardiac conduction - v81:[updateContainedPathway]
[UpdateTracker:9774648] Update Tracker - [Pathway:9678108] SARS-CoV-1 Infection - v81:[updateIndirectRLE]
[UpdateTracker:9774713] Update Tracker - [Pathway:211859] Biological oxidations - v81:[updateContainedPathway]
[UpdateTracker:9904316] Update Tracker - [Complex:6797611] Elongation Complex at DNA Repair Genes [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774737] Update Tracker - [Pathway:388396] GPCR downstream signalling - v81:[updateContainedPathway]
[UpdateTracker:9904301] Update Tracker - [EntityWithAccessionedSequence:140704] PalmC, 2HC-F3 [plasma membrane] - v81:[addHasModifiedResidue, modifyName]
[UpdateTracker:9774744] Update Tracker - [Reaction:168184] Activated TAK1 mediates phosphorylation of the IKK Complex - v81:[addLiteratureReference, add_removeOutput, modifyText]
[UpdateTracker:9904180] Update Tracker - [Complex:112425] Elongin Complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774790] Update Tracker - [Pathway:5578775] Ion homeostasis - v81:[addHasEvent]
[UpdateTracker:9904274] Update Tracker - [EntityWithAccessionedSequence:6808779] GPI-FOLR1 [transport vesicle] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9904312] Update Tracker - [Complex:167184] HIV-1 Tat-containing processive elongation complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774627] Update Tracker - [Pathway:381676] Glucagon-like Peptide-1 (GLP1) regulates insulin secretion - v81:[addHasEvent]
[UpdateTracker:9904205] Update Tracker - [Complex:975037] KRAB-ZNF / KAP Complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904333] Update Tracker - [DefinedSet:8867228] CEACAM1,3,5,6 [plasma membrane] - v81:[add_removeHasMember]
[UpdateTracker:9904319] Update Tracker - [Complex:9694269] SARS coronavirus gRNA:RTC:nascent RNA minus strand with mismatched nucleotide [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904324] Update Tracker - [SimpleEntity:6787328] dR5P [cytosol] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9904186] Update Tracker - [EntityWithAccessionedSequence:9694745] complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane] - v81:[modifyEndCoordinate, removeHasModifiedResidue]
[UpdateTracker:9904258] Update Tracker - [EntityWithAccessionedSequence:6814858] SRRT [nucleoplasm] - v81:[modifyName]
[UpdateTracker:9904287] Update Tracker - [Complex:870520] Ub-SMAD4:USP9X [cytosol] - v81:[add_removeHasComponent]
[UpdateTracker:9904252] Update Tracker - [DefinedSet:8940978] GPI-anchored proteins [plasma membrane] - v81:[removeHasMember]
[UpdateTracker:9904276] Update Tracker - [EntityWithAccessionedSequence:204085] GPI-CEACAM6 [plasma membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9904332] Update Tracker - [SimpleEntity:9699093] CMP-Neu5Ac [endoplasmic reticulum-Golgi intermediate compartment] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9904283] Update Tracker - [DefinedSet:1306878] NLRP3 elicitors:NLRP3 [cytosol] - v81:[updateContainedMemberOrCandidate]
[UpdateTracker:9904219] Update Tracker - [Complex:749447] Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904208] Update Tracker - [EntityWithAccessionedSequence:71868] PXLP-p-S15-PYGB [cytosol] - v81:[modifyName]
[UpdateTracker:9774682] Update Tracker - [Pathway:9020702] Interleukin-1 signaling - v81:[updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9904256] Update Tracker - [Complex:453332] PYGB b dimer:AMP [cytosol] - v81:[modifyName]
[UpdateTracker:9774702] Update Tracker - [Pathway:9694301] Maturation of replicase proteins - v81:[addHasEvent, updateContainedRLE]
[UpdateTracker:9904257] Update Tracker - [EntityWithAccessionedSequence:8850837] DHX16 [nucleoplasm] - v81:[addName]
[UpdateTracker:9774691] Update Tracker - [Pathway:2173793] Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9774701] Update Tracker - [FailedReaction:5228811] NFKBIA variant is not phosphorylated within IkBA:NF-kappaB - v81:[add_removeCatalystActivity]
[UpdateTracker:9774684] Update Tracker - [Pathway:2262752] Cellular responses to stress - v81:[updateContainedPathway]
[UpdateTracker:9904221] Update Tracker - [DefinedSet:4568769] AcK-histone H2B, H3, H4 [nucleoplasm] - v81:[add_removeHasMember]
[UpdateTracker:9904294] Update Tracker - [CandidateSet:974995] KRAB-ZNF [nucleoplasm] - v81:[removeHasCandidate]
[UpdateTracker:9904244] Update Tracker - [Complex:9713636] SARS-CoV-2 genomic RNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9774726] Update Tracker - [Pathway:382551] Transport of small molecules - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904174] Update Tracker - [Complex:77469] U4 ATAC:U5:U6 ATAC Complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904211] Update Tracker - [EntityWithAccessionedSequence:6799164] PXLP-PYGB [azurophil granule lumen] - v81:[modifyName]
[UpdateTracker:9774657] Update Tracker - [Reaction:2179276] SMURF2 monoubiquitinates SMAD3 - v81:[add_removeOutput]
[UpdateTracker:9904202] Update Tracker - [Complex:9694597] nsp7:nsp8:nsp12:nsp14:nsp10 [cytosol] - v81:[updateContainedComponent]
[UpdateTracker:9904233] Update Tracker - [EntityWithAccessionedSequence:6808768] GPI-CD55 [Golgi membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9904321] Update Tracker - [Complex:167071] HIV-1 Tat-containing paused processive elongation complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774733] Update Tracker - [Pathway:2173789] TGF-beta receptor signaling activates SMADs - v81:[updateContainedRLE]
[UpdateTracker:9904195] Update Tracker - [Complex:77475] ATAC C Complex with lariat containing 5'-end cleaved mRNA [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774664] Update Tracker - [Pathway:418555] G alpha (s) signalling events - v81:[addHasEvent]
[UpdateTracker:9774748] Update Tracker - [Pathway:71387] Metabolism of carbohydrates - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904320] Update Tracker - [SimpleEntity:8931886] UDP-GalNAc [endoplasmic reticulum lumen] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9774722] Update Tracker - [Pathway:1566948] Elastic fibre formation - v81:[updateIndirectRLE]
[UpdateTracker:9774765] Update Tracker - [Pathway:196071] Metabolism of steroid hormones - v81:[updateContainedPathway]
[UpdateTracker:9774766] Update Tracker - [Pathway:8982491] Glycogen metabolism - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904260] Update Tracker - [Complex:9713651] m7GpppA-SARS-CoV-2 plus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9774801] Update Tracker - [Pathway:9694635] Translation of Structural Proteins - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904323] Update Tracker - [Complex:71513] PYGM dimer a form [cytosol] - v81:[modifyName]
[UpdateTracker:9904296] Update Tracker - [Complex:9713644] SARS-CoV-2 genomic RNA (plus strand):RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9774820] Update Tracker - [Pathway:189200] Cellular hexose transport - v81:[addHasEvent]
[UpdateTracker:9774641] Update Tracker - [Reaction:5691439] BRISC complex deubiquitinates NLRP3 - v81:[modifyText]
[UpdateTracker:9904189] Update Tracker - [DefinedSet:791493] GPCRs that activate Gq/11 [plasma membrane] - v81:[add_removeHasMember]
[UpdateTracker:9774760] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v81:[addHasEvent, updateContainedPathway]
[UpdateTracker:9774788] Update Tracker - [Pathway:2142691] Synthesis of Leukotrienes (LT) and Eoxins (EX) - v81:[addHasEvent]
[UpdateTracker:9904343] Update Tracker - [Complex:113726] Elongation complex with separated and uncleaved transcript [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774771] Update Tracker - [Reaction:9694287] Cleavage of S protein into S1:S2 - v81:[addRegulator, modifyText]
[UpdateTracker:9904225] Update Tracker - [SimpleEntity:727815] CMP-Neu5Ac [Golgi lumen] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9774642] Update Tracker - [Pathway:8939211] ESR-mediated signaling - v81:[addHasEvent]
[UpdateTracker:9774800] Update Tracker - [Pathway:168179] Toll Like Receptor TLR1:TLR2 Cascade - v81:[updateContainedPathway]
[UpdateTracker:9904300] Update Tracker - [EntityWithAccessionedSequence:71862] PXLP-PYGB [cytosol] - v81:[modifyName]
[UpdateTracker:9904334] Update Tracker - [Complex:420519] GRM1-8:L-Glu [plasma membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904243] Update Tracker - [Complex:6794319] NRXNs:LIN7:CASK:APBA1 [plasma membrane] - v81:[updateContainedComponent]
[UpdateTracker:9774750] Update Tracker - [Pathway:5602358] Diseases associated with the TLR signaling cascade - v81:[updateIndirectRLE]
[UpdateTracker:9774630] Update Tracker - [Pathway:5689901] Metalloprotease DUBs - v81:[updateContainedRLE]
[UpdateTracker:9774780] Update Tracker - [Reaction:433823] Released NFkB complex migrates to the nucleus and turns on transcription - v81:[modifyText]
[UpdateTracker:9904268] Update Tracker - [EntityWithAccessionedSequence:6807756] GPI-CD55 [endoplasmic reticulum-Golgi intermediate compartment membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9774637] Update Tracker - [BlackBoxEvent:9694572] 3a localizes to the cell membrane - v81:[add_removeOutput]
[UpdateTracker:9904253] Update Tracker - [Complex:9694327] SARS-CoV-2 gRNA:RTC:nascent RNA minus strand:RTC inhibitors [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9774779] Update Tracker - [Reaction:9691335] nsp7 binds nsp8 - v81:[addLiteratureReference, add_removeInput, modifyText]
[UpdateTracker:9774757] Update Tracker - [Pathway:1296071] Potassium Channels - v81:[updateContainedPathway]
[UpdateTracker:9904277] Update Tracker - [Complex:9754743] SARS-CoV-2 dsRNA intermediates:IFIH1 [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904190] Update Tracker - [EntityWithAccessionedSequence:3900136] DDX5 [nucleoplasm] - v81:[addName]
[UpdateTracker:9774703] Update Tracker - [Pathway:168164] Toll Like Receptor 3 (TLR3) Cascade - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9774745] Update Tracker - [Pathway:390696] Adrenoceptors - v81:[addHasEvent]
[UpdateTracker:9904272] Update Tracker - [SimpleEntity:173594] UDP-D-glucose(2-) [endoplasmic reticulum lumen] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9774686] Update Tracker - [Pathway:1606322] ZBP1(DAI) mediated induction of type I IFNs - v81:[updateIndirectRLE]
[UpdateTracker:9774635] Update Tracker - [Pathway:168249] Innate Immune System - v81:[updateContainedPathway]
[UpdateTracker:9774734] Update Tracker - [Pathway:450294] MAP kinase activation - v81:[updateIndirectRLE]
[UpdateTracker:9774829] Update Tracker - [Pathway:390651] Dopamine receptors - v81:[addHasEvent]
[UpdateTracker:9774626] Update Tracker - [Pathway:434316] Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion - v81:[addHasEvent]
[UpdateTracker:9774736] Update Tracker - [Pathway:390648] Muscarinic acetylcholine receptors - v81:[addHasEvent]
[UpdateTracker:9774787] Update Tracker - [Pathway:400206] Regulation of lipid metabolism by PPARalpha - v81:[addHasEvent]
[UpdateTracker:9774772] Update Tracker - [Pathway:112315] Transmission across Chemical Synapses - v81:[updateContainedPathway]
[UpdateTracker:9904302] Update Tracker - [Complex:9694359] SARS coronavirus gRNA with secondary structure:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904214] Update Tracker - [Complex:9694618] SARS-CoV-2 gRNA:RTC:nascent RNA minus strand [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904266] Update Tracker - [DefinedSet:9754749] SARS-CoV-2 dsRNA with poly(U)-containing (-) strand:RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedMemberOrCandidate]
[UpdateTracker:9774759] Update Tracker - [Reaction:9699007] FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis - v81:[addLiteratureReference, addRegulator, add_removeOutput, modifyText]
[UpdateTracker:9774799] Update Tracker - [Pathway:8956320] Nucleotide biosynthesis - v81:[updateContainedPathway]
[UpdateTracker:9774826] Update Tracker - [Reaction:2328033] Fibrillin-1 binds latent TGF-beta - v81:[modifyText]
[UpdateTracker:9774812] Update Tracker - [Pathway:9694271] Assembly of the SARS-CoV-2 Replication-Transcription Complex (RTC) - v81:[addHasEvent, updateContainedRLE]
[UpdateTracker:9774633] Update Tracker - [Pathway:425407] SLC-mediated transmembrane transport - v81:[updateContainedPathway]
[UpdateTracker:9904213] Update Tracker - [Complex:9760493] LARP1:SARS-CoV-2 gRNA:RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9774828] Update Tracker - [Pathway:434048] TLR3 cascade - v81:[updateIndirectRLE]
[UpdateTracker:9774636] Update Tracker - [Pathway:391903] Eicosanoid ligand-binding receptors - v81:[updateContainedPathway]
[UpdateTracker:9904181] Update Tracker - [EntityWithAccessionedSequence:162687] GPI-PLAUR [endoplasmic reticulum membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9774677] Update Tracker - [Pathway:434131] NFkB activation mediated by RIP1 complexed with activated TLR3 - v81:[updateContainedRLE]
[UpdateTracker:9904273] Update Tracker - [EntityWithAccessionedSequence:6808771] GPI-CD55 [transport vesicle] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9774731] Update Tracker - [Pathway:9694676] Translation of Replicase and Assembly of the Replication Transcription Complex - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9774730] Update Tracker - [Pathway:375281] Hormone ligand-binding receptors - v81:[addHasEvent]
[UpdateTracker:9774781] Update Tracker - [Pathway:9705671] SARS-CoV-2 activates/modulates innate and adaptive immune responses - v81:[updateContainedRLE]
[UpdateTracker:9774827] Update Tracker - [Pathway:196791] Vitamin D (calciferol) metabolism - v81:[addHasEvent]
[UpdateTracker:9904239] Update Tracker - [Complex:9691364] nsp7:nsp8:nsp12 [cytosol] - v81:[add_removeHasComponent, updateContainedComponent]
[UpdateTracker:9774725] Update Tracker - [Pathway:428157] Sphingolipid metabolism - v81:[updateContainedPathway]
[UpdateTracker:9774792] Update Tracker - [Reaction:1467457] ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region - v81:[addLiteratureReference, add_removeInput, add_removeOutput, modifyText]
[UpdateTracker:9774709] Update Tracker - [Pathway:3295583] TRP channels - v81:[addHasEvent]
[UpdateTracker:9774655] Update Tracker - [Pathway:1430728] Metabolism - v81:[updateContainedPathway]
[UpdateTracker:9774671] Update Tracker - [Pathway:975871] MyD88 cascade initiated on plasma membrane - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904176] Update Tracker - [Complex:6797607] CDK12-Phosphorylated Elongation Complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904314] Update Tracker - [EntityWithAccessionedSequence:6801642] PLK2 gene [nucleoplasm] - v81:[modifyName]
[UpdateTracker:9904250] Update Tracker - [Complex:9759705] CNBP:SARS-CoV-2 G-rich RNA:RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904217] Update Tracker - [Complex:167091] HIV-1 Tat-containing arrested processive elongation complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904184] Update Tracker - [EntityWithAccessionedSequence:8940811] GPI-CEACAM5 [plasma membrane] - v81:[modifyName]
[UpdateTracker:9774707] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v81:[updateContainedPathway]
[UpdateTracker:9774741] Update Tracker - [Pathway:373080] Class B/2 (Secretin family receptors) - v81:[updateContainedPathway]
[UpdateTracker:9774803] Update Tracker - [Pathway:937061] TRIF(TICAM1)-mediated TLR4 signaling - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9774817] Update Tracker - [Pathway:163685] Integration of energy metabolism - v81:[updateContainedPathway]
[UpdateTracker:9774768] Update Tracker - [Pathway:8964038] LDL clearance - v81:[addHasEvent]
[UpdateTracker:9904201] Update Tracker - [Complex:9713653] SARS-CoV-2 plus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904228] Update Tracker - [Complex:6794330] LIN7:CASK:APBA1 [plasma membrane] - v81:[add_removeHasComponent]
[UpdateTracker:9774837] Update Tracker - [Reaction:9638125] PGM1:Mg2+ isomerises G1P to G6P - v81:[add_removeLiteratureReference, modifyText]
[UpdateTracker:9774776] Update Tracker - [Pathway:9694719] Maturation of protein 3a - v81:[updateContainedRLE]
[UpdateTracker:9774704] Update Tracker - [Pathway:975138] TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9774763] Update Tracker - [Pathway:380615] Serotonin clearance from the synaptic cleft - v81:[addHasEvent]
[UpdateTracker:9774631] Update Tracker - [Pathway:70370] Galactose catabolism - v81:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9774815] Update Tracker - [Pathway:191273] Cholesterol biosynthesis - v81:[addHasEvent]
[UpdateTracker:9774727] Update Tracker - [Pathway:211945] Phase I - Functionalization of compounds - v81:[addHasEvent, updateContainedPathway]
[UpdateTracker:9774809] Update Tracker - [Reaction:870479] USP9X (FAM) binds to ubiquitinated SMAD4 - v81:[add_removeInput]
[UpdateTracker:9774667] Update Tracker - [Pathway:196849] Metabolism of water-soluble vitamins and cofactors - v81:[updateContainedPathway]
[UpdateTracker:9774644] Update Tracker - [Pathway:8978868] Fatty acid metabolism - v81:[updateContainedPathway]
[UpdateTracker:9904327] Update Tracker - [EntityWithAccessionedSequence:6791189] SKIV2L2 [nucleoplasm] - v81:[addName]
[UpdateTracker:9774806] Update Tracker - [Pathway:375280] Amine ligand-binding receptors - v81:[updateContainedPathway]
[UpdateTracker:9904275] Update Tracker - [DefinedSet:380110] Ligand:GPCR complexes that activate Gq/11 [plasma membrane] - v81:[updateContainedMemberOrCandidate]
[UpdateTracker:9904297] Update Tracker - [SimpleEntity:4085435] CMP-Neu5Ac [cytosol] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9904285] Update Tracker - [EntityWithAccessionedSequence:5689801] GPI-CD59 [ER to Golgi transport vesicle membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9774676] Update Tracker - [Reaction:9694661] TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis - v81:[addLiteratureReference, addOutput, addRegulator, modifyText]
[UpdateTracker:9774669] Update Tracker - [Reaction:9691363] nsp12 binds nsp7 and nsp8 - v81:[add_removeInput]
[UpdateTracker:9774821] Update Tracker - [Pathway:72163] mRNA Splicing - Major Pathway - v81:[updateContainedRLE]
[UpdateTracker:9774670] Update Tracker - [Pathway:5688426] Deubiquitination - v81:[updateIndirectRLE]
[UpdateTracker:9774841] Update Tracker - [Reaction:168910] RIP1 facilitates IKK complex phosphorylation - v81:[modifyText]
[UpdateTracker:9904255] Update Tracker - [SimpleEntity:532204] AcGlcN1P [cytosol] - v81:[add_removeReferenceEntity, modifyName]
[UpdateTracker:9904234] Update Tracker - [Complex:9694731] SARS coronavirus 2 gRNA with secondary structure:RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904329] Update Tracker - [SimpleEntity:735700] UDP-GalNAc [Golgi lumen] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9904340] Update Tracker - [DefinedSet:9759710] SARS-CoV-2 G-rich RNA:RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedMemberOrCandidate]
[UpdateTracker:9904231] Update Tracker - [Complex:1306879] NLRP3 elicitor proteins:NLRP3 [cytosol] - v81:[add_removeHasComponent]
[UpdateTracker:9904306] Update Tracker - [Complex:9713652] SARS-CoV-2 minus strand subgenomic mRNAs:RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904194] Update Tracker - [Complex:71538] PYGM dimer, b form [cytosol] - v81:[modifyName]
[UpdateTracker:9774838] Update Tracker - [Pathway:1280218] Adaptive Immune System - v81:[updateContainedPathway]
[UpdateTracker:9904223] Update Tracker - [Complex:77473] ATAC C Complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774729] Update Tracker - [Pathway:913531] Interferon Signaling - v81:[updateContainedPathway]
[UpdateTracker:9904177] Update Tracker - [EntityWithAccessionedSequence:5689453] GPI-CD59 [endoplasmic reticulum membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9774719] Update Tracker - [Pathway:8953897] Cellular responses to stimuli - v81:[updateContainedPathway]
[UpdateTracker:9904187] Update Tracker - [Complex:9754740] SARS-CoV-2 5'-poly(U)-gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9774687] Update Tracker - [Pathway:379401] Dopamine clearance from the synaptic cleft - v81:[addHasEvent]
[UpdateTracker:9904171] Update Tracker - [Complex:167286] HIV-1 arrested processive elongation complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774761] Update Tracker - [Pathway:109581] Apoptosis - v81:[updateContainedPathway]
[UpdateTracker:9774712] Update Tracker - [Pathway:375276] Peptide ligand-binding receptors - v81:[addHasEvent, updateContainedPathway]
[UpdateTracker:9774650] Update Tracker - [Reaction:5609665] CHUK, IKBKB and IKBKG form IKK complex - v81:[modifyText]
[UpdateTracker:9774831] Update Tracker - [Pathway:418346] Platelet homeostasis - v81:[updateContainedPathway]
[UpdateTracker:9904339] Update Tracker - [Complex:113721] Arrested processive elongation complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904230] Update Tracker - [EntityWithAccessionedSequence:6808772] GPI-CD59 [Golgi membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9904315] Update Tracker - [Complex:9754744] SARS-CoV-2 gRNA:RTC: 5'-poly(U) RNA minus strand [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904245] Update Tracker - [EntityWithAccessionedSequence:264893] INS(25-110) [endoplasmic reticulum lumen] - v81:[addCellType]
[UpdateTracker:9774754] Update Tracker - [Pathway:193048] Androgen biosynthesis - v81:[addHasEvent]
[UpdateTracker:9774742] Update Tracker - [Pathway:1638091] Heparan sulfate/heparin (HS-GAG) metabolism - v81:[updateIndirectRLE]
[UpdateTracker:9774629] Update Tracker - [Reaction:2076611] HS3STs sulfate GlcN at C3 in heparan sulfate - v81:[modifyText]
[UpdateTracker:9904291] Update Tracker - [Complex:9683316] CTSL:CTSL inhibitors [endocytic vesicle lumen] - v81:[updateContainedComponent]
[UpdateTracker:9904328] Update Tracker - [SimpleEntity:735683] UDP-GalNAc [cytosol] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9774715] Update Tracker - [Pathway:422356] Regulation of insulin secretion - v81:[addHasEvent, updateContainedPathway]
[UpdateTracker:9774675] Update Tracker - [Pathway:3371497] HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand - v81:[addHasEvent]
[UpdateTracker:9774692] Update Tracker - [Pathway:397014] Muscle contraction - v81:[updateContainedPathway]
[UpdateTracker:9774770] Update Tracker - [Pathway:5578768] Physiological factors - v81:[addHasEvent]
[UpdateTracker:9774679] Update Tracker - [Pathway:933542] TRAF6 mediated NF-kB activation - v81:[updateContainedRLE]
[UpdateTracker:9774656] Update Tracker - [Pathway:388479] Vasopressin-like receptors - v81:[addHasEvent]
[UpdateTracker:9774660] Update Tracker - [Pathway:168928] DDX58/IFIH1-mediated induction of interferon-alpha/beta - v81:[updateIndirectRLE]
[UpdateTracker:9904175] Update Tracker - [Complex:877381] NLRP3 elicitors:NLRP3 oligomer:ASC [cytosol] - v81:[updateContainedComponent]
[UpdateTracker:9774735] Update Tracker - [Pathway:111453] BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members - v81:[addHasEvent]
[UpdateTracker:9774720] Update Tracker - [Pathway:1296061] HCN channels - v81:[addHasEvent]
[UpdateTracker:9774783] Update Tracker - [Pathway:168188] Toll Like Receptor TLR6:TLR2 Cascade - v81:[updateContainedPathway]
[UpdateTracker:9774711] Update Tracker - [Pathway:196757] Metabolism of folate and pterines - v81:[addHasEvent]
[UpdateTracker:9774802] Update Tracker - [Pathway:168638] NOD1/2 Signaling Pathway - v81:[updateContainedRLE]
[UpdateTracker:9774767] Update Tracker - [Reaction:9694579] Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell - v81:[addRegulator]
[UpdateTracker:9904299] Update Tracker - [EntityWithAccessionedSequence:5689804] GPI-CD59 [endoplasmic reticulum-Golgi intermediate compartment membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9774774] Update Tracker - [Pathway:9679506] SARS-CoV Infections - v81:[updateContainedPathway]
[UpdateTracker:9904270] Update Tracker - [CandidateSet:453340] active PYGM and PYGB dimers [cytosol] - v81:[updateContainedMemberOrCandidate]
[UpdateTracker:9774804] Update Tracker - [Pathway:166658] Complement cascade - v81:[updateContainedPathway]
[UpdateTracker:9774823] Update Tracker - [Pathway:390650] Histamine receptors - v81:[addHasEvent]
[UpdateTracker:9904212] Update Tracker - [Complex:9755962] SARS-CoV-2 dsRNA intermediates:DDX58 [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904196] Update Tracker - [Complex:925458] NLRP3 elicitors:NLRP3 oligomer:ASC:Procaspase-1 [cytosol] - v81:[updateContainedComponent]
[UpdateTracker:9774756] Update Tracker - [Pathway:109582] Hemostasis - v81:[updateContainedPathway]
[UpdateTracker:9774652] Update Tracker - [Pathway:5689880] Ub-specific processing proteases - v81:[updateContainedRLE]
[UpdateTracker:9904331] Update Tracker - [Complex:113720] Paused processive elongation complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904247] Update Tracker - [Complex:167283] HIV-1 paused processive elongation complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904182] Update Tracker - [Complex:6797614] CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904337] Update Tracker - [EntityWithAccessionedSequence:9694638] complex N-glycan-PALM-Spike S1 Fragment [virion membrane] - v81:[modifyEndCoordinate, removeHasModifiedResidue]
[UpdateTracker:9774658] Update Tracker - [Pathway:419812] Calcitonin-like ligand receptors - v81:[addHasEvent]
[UpdateTracker:9774708] Update Tracker - [Pathway:2129379] Molecules associated with elastic fibres - v81:[updateContainedRLE]
[UpdateTracker:9904308] Update Tracker - [Complex:9691348] nsp7:nsp8 [cytosol] - v81:[add_removeHasComponent]
[UpdateTracker:9774688] Update Tracker - [Pathway:170834] Signaling by TGF-beta Receptor Complex - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9774661] Update Tracker - [Pathway:9006335] Signaling by Erythropoietin - v81:[addHasEvent]
[UpdateTracker:9904191] Update Tracker - [Complex:2161325] Elastic fibre with associated proteins [extracellular region] - v81:[updateContainedComponent]
[UpdateTracker:9904280] Update Tracker - [EntityWithAccessionedSequence:5689806] GPI-FOLR1 [ER to Golgi transport vesicle membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9904269] Update Tracker - [EntityWithAccessionedSequence:5689457] GPI-FOLR1 [endoplasmic reticulum membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9774663] Update Tracker - [Pathway:9678110] Attachment and Entry - v81:[updateContainedRLE]
[UpdateTracker:9904263] Update Tracker - [Complex:71581] PYGL dimer b form [cytosol] - v81:[modifyName]
[UpdateTracker:9774839] Update Tracker - [Pathway:70221] Glycogen breakdown (glycogenolysis) - v81:[addLiteratureReference, add_removeHasEvent, modifyText, updateContainedRLE]
[UpdateTracker:9774693] Update Tracker - [Pathway:166016] Toll Like Receptor 4 (TLR4) Cascade - v81:[updateContainedPathway]
[UpdateTracker:9774716] Update Tracker - [Pathway:166166] MyD88-independent TLR4 cascade - v81:[updateContainedPathway]
[UpdateTracker:9774844] Update Tracker - [Pathway:936837] Ion transport by P-type ATPases - v81:[addHasEvent]
[UpdateTracker:9904281] Update Tracker - [SimpleEntity:742361] UDP-Xyl [Golgi lumen] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9774645] Update Tracker - [Pathway:9694631] Maturation of nucleoprotein - v81:[addHasEvent]
[UpdateTracker:9774749] Update Tracker - [Pathway:5619115] Disorders of transmembrane transporters - v81:[updateContainedPathway]
[UpdateTracker:9904203] Update Tracker - [Complex:9698995] S2 trimer [plasma membrane] - v81:[addName]
[UpdateTracker:9904282] Update Tracker - [SimpleEntity:1889970] UDP-GlcA [Golgi lumen] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9774782] Update Tracker - [Pathway:1266738] Developmental Biology - v81:[addHasEvent, modifyText, updateContainedPathway]
[UpdateTracker:9774755] Update Tracker - [Pathway:8964043] Plasma lipoprotein clearance - v81:[updateContainedPathway]
[UpdateTracker:9774751] Update Tracker - [Pathway:382556] ABC-family proteins mediated transport - v81:[updateContainedRLE]
[UpdateTracker:9904345] Update Tracker - [Complex:9694725] SARS-CoV-2 gRNA:RTC:RNA primer [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904188] Update Tracker - [Complex:167482] HIV-1 aborted elongation complex after arrest [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904236] Update Tracker - [DefinedSet:8941069] proteins with cleaved GPI-anchors [extracellular region] - v81:[removeHasMember]
[UpdateTracker:9774696] Update Tracker - [Pathway:112316] Neuronal System - v81:[updateContainedPathway]
[UpdateTracker:9774798] Update Tracker - [Pathway:372790] Signaling by GPCR - v81:[updateContainedPathway]
[UpdateTracker:9774717] Update Tracker - [Pathway:9705683] SARS-CoV-2-host interactions - v81:[updateIndirectRLE]
[UpdateTracker:9904254] Update Tracker - [SimpleEntity:417855] UDP-D-glucose(2-) [extracellular region] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9774724] Update Tracker - [Pathway:2022928] HS-GAG biosynthesis - v81:[updateContainedRLE]
[UpdateTracker:9904226] Update Tracker - [DefinedSet:481033] Platelet alpha granule contents [extracellular region] - v81:[add_removeHasMember]
[UpdateTracker:9904336] Update Tracker - [SimpleEntity:4085418] CMP-Neu5Ac [nucleoplasm] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9774672] Update Tracker - [Pathway:2142753] Arachidonic acid metabolism - v81:[updateContainedPathway]
[UpdateTracker:9904200] Update Tracker - [SimpleEntity:1678617] aldehydo-L-iduronic acid [lysosomal lumen] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9904246] Update Tracker - [EntityWithAccessionedSequence:6799133] GPI-CEACAM6 [azurophil granule membrane] - v81:[addHasModifiedResidue, modifyName]
[UpdateTracker:9774697] Update Tracker - [Pathway:445355] Smooth Muscle Contraction - v81:[addHasEvent]
[UpdateTracker:9904303] Update Tracker - [Complex:453344] PYGM b dimer:AMP [cytosol] - v81:[modifyName]
[UpdateTracker:9774769] Update Tracker - [Pathway:9694614] Attachment and Entry - v81:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9904235] Update Tracker - [SimpleEntity:29410] UDP-D-glucose(2-) [cytosol] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9904271] Update Tracker - [ChemicalDrug:9731198] nirmatrelvir [cytosol] - v81:[modifyName]
[UpdateTracker:9774753] Update Tracker - [Pathway:500753] Pyrimidine biosynthesis - v81:[addHasEvent]
[UpdateTracker:9774796] Update Tracker - [Pathway:400451] Free fatty acids regulate insulin secretion - v81:[updateContainedPathway]
[UpdateTracker:9904232] Update Tracker - [Complex:9713643] m7GpppA-capped SARS-CoV-2 genomic RNA (plus strand):RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904317] Update Tracker - [Polymer:1296409] NLRP3 elicitors:NLRP3 oligomer [cytosol] - v81:[updateContainedRepeatedUnit]
[UpdateTracker:9774833] Update Tracker - [Pathway:5663205] Infectious disease - v81:[updateContainedPathway]
[UpdateTracker:9774673] Update Tracker - [Pathway:381340] Transcriptional regulation of white adipocyte differentiation - v81:[addHasEvent]
[UpdateTracker:9774689] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v81:[addHasEvent]
[UpdateTracker:9774700] Update Tracker - [Pathway:381771] Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) - v81:[addHasEvent]
[UpdateTracker:9904335] Update Tracker - [EntityWithAccessionedSequence:6808775] GPI-CD59 [transport vesicle] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9774816] Update Tracker - [Pathway:76002] Platelet activation, signaling and aggregation - v81:[updateContainedPathway]
[UpdateTracker:9774764] Update Tracker - [Pathway:196854] Metabolism of vitamins and cofactors - v81:[updateContainedPathway]
[UpdateTracker:9774794] Update Tracker - [Pathway:168181] Toll Like Receptor 7/8 (TLR7/8) Cascade - v81:[addHasEvent]
[UpdateTracker:9904210] Update Tracker - [EntityWithAccessionedSequence:8867890] PRPF40A [nucleoplasm] - v81:[addName]
[UpdateTracker:9904207] Update Tracker - [Complex:112433] Elongation complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774665] Update Tracker - [BlackBoxEvent:870477] Ubiquitinated SMAD4 translocates from the nucleus to the cytosol - v81:[add_removeInput, add_removeOutput]
[UpdateTracker:9904224] Update Tracker - [EntityWithAccessionedSequence:158946] GPI-PLAUR [plasma membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9904241] Update Tracker - [EntityWithAccessionedSequence:5689808] GPI-FOLR1 [endoplasmic reticulum-Golgi intermediate compartment membrane] - v81:[add_removeHasModifiedResidue]
[UpdateTracker:9904215] Update Tracker - [SimpleEntity:9034046] UDP-GalNAc [extracellular region] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9774834] Update Tracker - [Reaction:9630923] NF-kappa-B inhibitor binds NF-kappa-B complex - v81:[modifyText]
[UpdateTracker:9774824] Update Tracker - [Pathway:112314] Neurotransmitter receptors and postsynaptic signal transmission - v81:[addHasEvent]
[UpdateTracker:9904284] Update Tracker - [EntityWithAccessionedSequence:9694343] complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane] - v81:[addHasModifiedResidue, modifyEndCoordinate, modifyStartCoordinate]
[UpdateTracker:9904218] Update Tracker - [Complex:113722] Aborted elongation complex after arrest [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774805] Update Tracker - [Pathway:877300] Interferon gamma signaling - v81:[addHasEvent]
[UpdateTracker:9774791] Update Tracker - [Pathway:5576890] Phase 3 - rapid repolarisation - v81:[addHasEvent]
[UpdateTracker:9774632] Update Tracker - [Pathway:168898] Toll-like Receptor Cascades - v81:[updateContainedPathway]
[UpdateTracker:9774706] Update Tracker - [Pathway:446652] Interleukin-1 family signaling - v81:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9904279] Update Tracker - [Complex:749451] Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904322] Update Tracker - [Complex:9694404] SARS-CoV-2 gRNA complement (minus strand):RTC [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904222] Update Tracker - [Complex:5420896] PRP19-CDC5L complex [nucleoplasm] - v81:[addName]
[UpdateTracker:9774752] Update Tracker - [Pathway:392851] Prostacyclin signalling through prostacyclin receptor - v81:[addHasEvent]
[UpdateTracker:9904199] Update Tracker - [Complex:167193] Tat-containing elongation complex prior to separation [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774674] Update Tracker - [Pathway:556833] Metabolism of lipids - v81:[updateContainedPathway]
[UpdateTracker:9774775] Update Tracker - [Pathway:434001] TAK1 activates NFkB by phosphorylation and activation of IKKs complex - v81:[updateContainedRLE]
[UpdateTracker:9774747] Update Tracker - [Pathway:983712] Ion channel transport - v81:[updateContainedPathway]
[UpdateTracker:9904220] Update Tracker - [Complex:167460] HIV-1 Tat-containing aborted elongation complex after arrest [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774710] Update Tracker - [BlackBoxEvent:9694592] 3CLp dimer binds 3CLp inhibitors - v81:[modifyText]
[UpdateTracker:9904295] Update Tracker - [Complex:9694740] nsp7:nsp8:nsp12:nsp14:nsp10:nsp13:nsp15 [cytosol] - v81:[updateContainedComponent]
[UpdateTracker:9774813] Update Tracker - [Pathway:15869] Metabolism of nucleotides - v81:[updateContainedPathway]
[UpdateTracker:9774814] Update Tracker - [Pathway:909733] Interferon alpha/beta signaling - v81:[addHasEvent]
[UpdateTracker:9774723] Update Tracker - [Reaction:5684275] IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 - v81:[add_removeCatalystActivity]
[UpdateTracker:9774646] Update Tracker - [Pathway:9006931] Signaling by Nuclear Receptors - v81:[updateContainedPathway]
[UpdateTracker:9904304] Update Tracker - [Complex:6797602] CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774797] Update Tracker - [Reaction:9685655] CTSL bind CTSL inhibitors - v81:[addLiteratureReference]
[UpdateTracker:9774705] Update Tracker - [Pathway:1660661] Sphingolipid de novo biosynthesis - v81:[addHasEvent]
[UpdateTracker:9774762] Update Tracker - [Pathway:433871] TRAF6 mediated induction of proinflammatory cytokines - v81:[updateIndirectRLE]
[UpdateTracker:9774835] Update Tracker - [Pathway:75105] Fatty acyl-CoA biosynthesis - v81:[addHasEvent]
[UpdateTracker:9904259] Update Tracker - [Complex:167081] HIV-1 processive elongation complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774842] Update Tracker - [Pathway:212436] Generic Transcription Pathway - v81:[updateContainedPathway]
[UpdateTracker:9774746] Update Tracker - [Pathway:75205] Dissolution of Fibrin Clot - v81:[addHasEvent]
[UpdateTracker:9774690] Update Tracker - [Pathway:1280215] Cytokine Signaling in Immune system - v81:[updateContainedPathway]
[UpdateTracker:9774795] Update Tracker - [Pathway:9694516] SARS-CoV-2 Infection - v81:[add_removeHasEvent]
[UpdateTracker:9774654] Update Tracker - [Pathway:433822] NFkB and MAPK activation mediated by TRAF6 - v81:[updateIndirectRLE]
[UpdateTracker:9774739] Update Tracker - [Pathway:168176] Toll Like Receptor 5 (TLR5) Cascade - v81:[updateContainedPathway]
[UpdateTracker:9774634] Update Tracker - [Pathway:500792] GPCR ligand binding - v81:[updateContainedPathway]
[UpdateTracker:9904193] Update Tracker - [Complex:71586] PYGL dimer a form [cytosol] - v81:[modifyName]
[UpdateTracker:9774659] Update Tracker - [Pathway:5678895] Defective CFTR causes cystic fibrosis - v81:[addHasEvent]
[UpdateTracker:9774793] Update Tracker - [Pathway:1810476] RIP-mediated NFkB activation via ZBP1 - v81:[updateContainedRLE]
[UpdateTracker:9904238] Update Tracker - [EntityWithAccessionedSequence:71993] CPSF3 [nucleoplasm] - v81:[addName]
[UpdateTracker:9774840] Update Tracker - [Pathway:2980736] Peptide hormone metabolism - v81:[updateContainedPathway]
[UpdateTracker:9904288] Update Tracker - [EntityWithAccessionedSequence:71989] CPSF1 [nucleoplasm] - v81:[addName]
[UpdateTracker:9774685] Update Tracker - [Pathway:426117] Cation-coupled Chloride cotransporters - v81:[addHasEvent]
[UpdateTracker:9774698] Update Tracker - [Pathway:9679191] Potential therapeutics for SARS - v81:[addHasEvent]
[UpdateTracker:9904313] Update Tracker - [DefinedSet:2161378] Elastic fibre-asociated proteins [extracellular region] - v81:[removeHasMember]
[UpdateTracker:9904240] Update Tracker - [Complex:167082] HIV-1 elongation complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9904262] Update Tracker - [DefinedSet:420516] GRM1-8 [plasma membrane] - v81:[add_removeHasMember]
[UpdateTracker:9774623] Update Tracker - [Pathway:1237044] Erythrocytes take up carbon dioxide and release oxygen - v81:[addHasEvent]
[UpdateTracker:9774773] Update Tracker - [Pathway:112311] Neurotransmitter clearance - v81:[updateContainedPathway]
[UpdateTracker:9774628] Update Tracker - [Pathway:2162123] Synthesis of Prostaglandins (PG) and Thromboxanes (TX) - v81:[addHasEvent]
[UpdateTracker:9774653] Update Tracker - [BlackBoxEvent:9694780] Spike translocates to ERGIC - v81:[addLiteratureReference, modifyText]
[UpdateTracker:9774666] Update Tracker - [Reaction:5684267] IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex - v81:[add_removeCatalystActivity]
[UpdateTracker:9774830] Update Tracker - [Pathway:8957322] Metabolism of steroids - v81:[updateContainedPathway]
[UpdateTracker:9774786] Update Tracker - [Pathway:174577] Activation of C3 and C5 - v81:[addHasEvent]
[UpdateTracker:9904307] Update Tracker - [CandidateSet:9693170] CTSL inhibitors [endocytic vesicle lumen] - v81:[addHasCandidate]
[UpdateTracker:9904261] Update Tracker - [Complex:167185] HIV-1 elongation complex containing Tat [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774680] Update Tracker - [Pathway:193144] Estrogen biosynthesis - v81:[addHasEvent]
[UpdateTracker:9904341] Update Tracker - [Complex:9698997] S1:S2:M lattice:E protein [plasma membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904192] Update Tracker - [Complex:9694255] SARS-CoV-2 gRNA:RTC:RNA primer:RTC inhibitors [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904251] Update Tracker - [Complex:71869] PYGB dimer a form [cytosol] - v81:[modifyName]
[UpdateTracker:9774758] Update Tracker - [Pathway:2173796] SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription - v81:[addHasEvent, updateContainedRLE]
[UpdateTracker:9774699] Update Tracker - [Reaction:140761] sequestered tissue factor -> tissue factor - v81:[modifyText]
[UpdateTracker:9774662] Update Tracker - [Pathway:174824] Plasma lipoprotein assembly, remodeling, and clearance - v81:[updateContainedPathway]
[UpdateTracker:9774740] Update Tracker - [Pathway:573298] NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation - v81:[updateIndirectRLE]
[UpdateTracker:9904179] Update Tracker - [Complex:71981] U5 snRNP [nucleoplasm] - v81:[removeHasComponent]
[UpdateTracker:9904265] Update Tracker - [EntityWithAccessionedSequence:3700996] MDM2 gene [nucleoplasm] - v81:[modifyName]
[UpdateTracker:9904292] Update Tracker - [Complex:9694690] SARS-CoV-2 gRNA complement (minus strand):RTC:RTC inhibitors [double membrane vesicle viral factory outer membrane] - v81:[updateContainedComponent]
[UpdateTracker:9904198] Update Tracker - [Complex:113719] Processive elongation complex [nucleoplasm] - v81:[updateContainedComponent]
[UpdateTracker:9774678] Update Tracker - [Reaction:870449] TRIM33 monoubiquitinates SMAD4 - v81:[add_removeOutput]
[UpdateTracker:9774789] Update Tracker - [Pathway:391908] Prostanoid ligand receptors - v81:[addHasEvent]
[UpdateTracker:9904326] Update Tracker - [EntityWithAccessionedSequence:1234098] ARNT [nucleoplasm] - v81:[addName, modifyStartCoordinate]
[UpdateTracker:9774695] Update Tracker - [Pathway:1480926] O2/CO2 exchange in erythrocytes - v81:[updateContainedPathway]
[UpdateTracker:9774668] Update Tracker - [Pathway:5576893] Phase 2 - plateau phase - v81:[addHasEvent]
[UpdateTracker:9774694] Update Tracker - [Pathway:168643] Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways - v81:[updateIndirectRLE]
[UpdateTracker:9904216] Update Tracker - [EntityWithAccessionedSequence:6801536] PXLP-PYGB [extracellular region] - v81:[modifyName]
[UpdateTracker:9904330] Update Tracker - [DefinedSet:5144545] AcK15-histone H3, AcK-HIST1H4 [nucleoplasm] - v81:[add_removeHasMember]
[UpdateTracker:9774640] Update Tracker - [Pathway:5619084] ABC transporter disorders - v81:[updateContainedPathway]
[UpdateTracker:9904342] Update Tracker - [Complex:71863] PYGB dimer b form [cytosol] - v81:[modifyName]
[UpdateTracker:9774822] Update Tracker - [Reaction:168140] Active IKK Complex phosphorylates NF-kappa-B inhibitor - v81:[modifyText]
[UpdateTracker:9774777] Update Tracker - [Pathway:456926] Thrombin signalling through proteinase activated receptors (PARs) - v81:[addHasEvent]
[UpdateTracker:9774818] Update Tracker - [Pathway:983705] Signaling by the B Cell Receptor (BCR) - v81:[updateContainedPathway]
[UpdateTracker:9904178] Update Tracker - [Complex:77506] U4:U5:U6 tri-snRNP complex [nucleoplasm] - v81:[addHasComponent, updateContainedComponent]
[UpdateTracker:9904183] Update Tracker - [SimpleEntity:742353] UDP-Xyl [cytosol] - v81:[addName, add_removeReferenceEntity]
[UpdateTracker:9774738] Update Tracker - [Reaction:2186775] Rnf111 ubiquitinates Smad7 - v81:[modifyText]
[UpdateTracker:9774651] Update Tracker - [Pathway:975155] MyD88 dependent cascade initiated on endosome - v81:[updateContainedPathway]
[UpdateTracker:9904185] Update Tracker - [SimpleEntity:449703] AcGlcN6P [cytosol] - v81:[addName, add_removeReferenceEntity]

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