Reactome | Goding, CR

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created	[InstanceEdit:9730406] Rothfels, Karen, 2021-05-07
dbId	9730402
displayName	Goding, CR
firstname	Colin R
initial	CR
publications	[LiteratureReference:9730403] MITF-the first 25 years [LiteratureReference:9854810] Connecting Metabolic Rewiring With Phenotype Switching in Melanoma [LiteratureReference:9857138] Cancer stem cells versus phenotype-switching in melanoma [LiteratureReference:9926258] Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities [LiteratureReference:9857331] Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas [LiteratureReference:9768259] Tbx3 represses E-cadherin expression and enhances melanoma invasiveness [LiteratureReference:9857326] Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor [LiteratureReference:9858184] The Brn-2 transcription factor links activated BRAF to melanoma proliferation [LiteratureReference:9855344] UV-induced expression of key component of the tanning process, the POMC and MC1R genes, is dependent on the p-38-activated upstream stimulating factor-1 (USF-1) [LiteratureReference:9917229] The microphthalmia-associated transcription factor Mitf interacts with beta-catenin to determine target gene expression [LiteratureReference:9858091] Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin [LiteratureReference:9825487] Oncogenic B-RAF(V600E) signaling induces the T-Box3 transcriptional repressor to repress E-cadherin and enhance melanoma cell invasion [LiteratureReference:9825509] TBX3 Promotes Melanoma Migration by Transcriptional Activation of ID1, which Prevents Activation of E-Cadherin by MITF [LiteratureReference:9825809] Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression [LiteratureReference:9858093] Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells [LiteratureReference:9857178] Mitf regulation of Dia1 controls melanoma proliferation and invasiveness [LiteratureReference:9863499] ERK-regulated differential expression of the Mitf 6a/b splicing isoforms in melanoma [LiteratureReference:9732011] MITF is a critical regulator of the carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in malignant melanoma [LiteratureReference:9912067] Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy [LiteratureReference:9863234] Acetylation reprograms MITF target selectivity and residence time [LiteratureReference:9824912] BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export [LiteratureReference:9858083] BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma [LiteratureReference:9857276] Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma [LiteratureReference:9907059] BRN2 is a non-canonical melanoma tumor-suppressor [LiteratureReference:9863228] Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution
schemaClass	Person
surname	Goding

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