Based on studies in Drosophila, RAP1GDS1, an orthologue of D...
| created | [InstanceEdit:9693761] Orlic-Milacic, Marija, 2020-07-06 |
| dbId | 9693765 |
| displayName | Based on studies in Drosophila, RAP1GDS1, an orthologue of D... |
| literatureReference | |
| schemaClass | Summation |
| text | Based on studies in Drosophila, RAP1GDS1, an orthologue of Drosophila Vimar, is a mitochondrial outer membrane-bound atypical guanine nucleotide exchange factor (GEF) that activates mitochondria-associated atypical RHO GTPase RHOT2, an orthologue of Drosophila Miro, by catalyzing GDP to GTP exchange, resulting in formation of the active RHOT2:GTP complex (Ding et al. 2016). |
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