Active GTP bound RHOJ binds the following effectors:
FMNL...

created [InstanceEdit:9693383] Orlic-Milacic, Marija, 2020-07-01
dbId 9693381
displayName Active GTP bound RHOJ binds the following effectors:
FMNL...
modified [InstanceEdit:9714877] Orlic-Milacic, Marija, 2021-02-16
schemaClass Summation
text Active GTP bound RHOJ binds the following effectors:
FMNL3 (Richards et al. 2015)
PAK1 (Vignal et al. 2000, Ho et al. 2012; Bagci et al. 2020)
PAK3 (Sundararaman et al. 2020)
WIP2 WASP complex, through direct interaction with WAS (WASP) (Vignal et al. 2000), WASL (Abe et al. 2003, Bagci et al. 2020) and WIPF2 (Bagci et al. 2020)

The following RHOJ effectors are annotated as candidates because the knowledge on their relationship with RHOJ is limited:
ARHGAP1 (Bagci et al. 2020)
ARHGEF7 (Bagci et al. 2020)
ARL13B (Bagci et al. 2020)
CAV1 (Bagci et al. 2020)
CDC42 (Bagci et al. 2020)
CDC42BPA (Bagci et al. 2020)
CDC42BPB (Bagci et al. 2020)
CDC42EP1 (Bagci et al. 2020)
CPNE8 (Bagci et al. 2020)
DEPDC1B (Bagci et al. 2020)
DIAPH3 (Bagci et al. 2020)
FNBP1 (Bagci et al. 2020)
FNBP1L (Bagci et al. 2020)
GIT1 (Bagci et al. 2020)
GIT2 (Bagci et al. 2020)
GJA1 (Bagci et al. 2020)
IQGAP3 (Bagci et al. 2020)
JUP (Bagci et al. 2020)
LAMTOR1 (Bagci et al. 2020)
MPP7 (Bagci et al. 2020)
NIPSNAP2 (Bagci et al. 2020)
PAK2 (Bagci et al. 2020)
PAK4 (Bagci et al. 2020)
RAB7A (Bagci et al. 2020)
SCRIB (Bagci et al. 2020)
SLC1A5 (Bagci et al. 2020)
SLC4A7 (Bagci et al. 2020)
SNAP23 (Bagci et al. 2020)
STEAP3 (Bagci et al. 2020)
STOM (Bagci et al. 2020)
TFRC (Bagci et al. 2020)
TMPO (Bagci et al. 2020)
VAMP3 (Bagci et al. 2020)
VANGL1 (Bagci et al. 2020)
WWP2 (Bagci et al. 2020)

In the screen by Bagci et al. 2020, active RHOJ was found to interact with LBR and YKT6, two proteins that localize to the endoplasmic reticulum membrane. However, since RHOJ localization at the endoplasmic reticulum membrane has not been reported, these two interactions have not been annotated.

RHOJ does not interact with the following RHO GTPase effectors:
ARFGAP2 (Bagci et al. 2020)
ARFGAP3 (Bagci et al. 2020)
CDC42EP2 (Bagci et al. 2020)
CDC42EP4 (Bagci et al. 2020)
CDC42SE2 (Bagci et al. 2020)
FMNL1 (Bagci et al. 2020)
FMNL2 (Bagci et al. 2020)
GFOD1 (Bagci et al. 2020)
GOLGA8R (Bagci et al. 2020)
KCTD3 (Bagci et al. 2020)
KIAA0355 (Bagci et al. 2020)
PLEKHG3 (Bagci et al. 2020)
ROCK1 (Bagci et al. 2020)
ROCK2 (Bagci et al. 2020)
SH3PXD2A (Bagci et al. 2020)
SHKBP1 (Bagci et al. 2020)
SLK (Bagci et al. 2020)
WDR81 (Bagci et al. 2020)
WDR91 (Bagci et al. 2020)
WIPF1 (Bagci et al. 2020)
WIPF3 (Bagci et al. 2020)
Cite Us!