KIT receptors with mutations at residue D816 are resistant t...

created [InstanceEdit:9671482] Rothfels, Karen, 2019-12-19
dbId 9671474
displayName KIT receptors with mutations at residue D816 are resistant t...
modified [InstanceEdit:9672956] Rothfels, Karen, 2020-01-03
schemaClass Summation
text KIT receptors with mutations at residue D816 are resistant to inhibition by sorafenib, while other activation loop mutations show variable sensitivity (Guida et al, 2007; Heinrich et al, 2012; Serrano et al, 2019).
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