Reactome | Kaufman, RJ

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Kaufman, RJ Show undefined attributes

created	[InstanceEdit:9661631] Shamovsky, Veronica, 2019-09-18
dbId	9661662
displayName	Kaufman, RJ
firstname	R J
initial	RJ
publications	[LiteratureReference:9661613] Post-translational modifications required for coagulation factor secretion and function [LiteratureReference:9661577] Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells [LiteratureReference:9661682] Biosynthesis, assembly and secretion of coagulation factor VIII [LiteratureReference:9670687] Expression, purification, and characterization of recombinant gamma-carboxylated factor IX synthesized in Chinese hamster ovary cells [LiteratureReference:9662038] Factor VIII C2 domain missense mutations exhibit defective trafficking of biologically functional proteins [LiteratureReference:9833780] Double-stranded (ds) RNA binding and not dimerization correlates with the activation of the dsRNA-dependent protein kinase (PKR) [LiteratureReference:9934348] Proteolytic requirements for thrombin activation of anti-hemophilic factor (factor VIII) [LiteratureReference:9822569] Cleavage requirements for activation of factor V by factor Xa [LiteratureReference:9668041] Identification and functional importance of tyrosine sulfate residues within recombinant factor VIII [LiteratureReference:9661561] Sequences in the coding region of clotting factor VIII act as dominant inhibitors of RNA accumulation and protein production [LiteratureReference:9661553] A 110-amino acid region within the A1-domain of coagulation factor VIII inhibits secretion from mammalian cells [LiteratureReference:9661645] ATP-dependent dissociation of non-disulfide-linked aggregates of coagulation factor VIII is a rate-limiting step for secretion [LiteratureReference:9661616] Differential interaction of coagulation factor VIII and factor V with protein chaperones calnexin and calreticulin [LiteratureReference:9661574] Mutagenesis of a potential immunoglobulin-binding protein-binding site enhances secretion of coagulation factor VIII [LiteratureReference:9668032] Identification of individual tyrosine sulfation sites within factor VIII required for optimal activity and efficient thrombin cleavage [LiteratureReference:9670046] Mild hemophilia A caused by increased rate of factor VIII A2 subunit dissociation: evidence for nonproteolytic inactivation of factor VIIIa in vivo [LiteratureReference:9670042] Hemophilia A mutations associated with 1-stage/2-stage activity discrepancy disrupt protein-protein interactions within the triplicated A domains of thrombin-activated factor VIIIa [LiteratureReference:9667136] The role of von Willebrand factor multimers and propeptide cleavage in binding and stabilization of factor VIII [LiteratureReference:9662324] The molecular basis for cross-reacting material-positive hemophilia A due to missense mutations within the A2-domain of factor VIII [LiteratureReference:9667163] The effect of plasma von Willebrand factor on the binding of human factor VIII to thrombin-activated human platelets [LiteratureReference:9661611] Molecular cloning of a cDNA encoding human antihaemophilic factor [LiteratureReference:9835351] TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR
schemaClass	Person
surname	Kaufman

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