Reactome | Kazi, JU

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Kazi, JU Show undefined attributes

created	[InstanceEdit:9605256] Varusai, Thawfeek, 2018-04-09
crossReference	[DatabaseIdentifier:9706531] ORCID:0000-0002-0719-5336
dbId	9605262
displayName	Kazi, JU
firstname	Julhash U
initial	JU
modified	[InstanceEdit:9706532] Rothfels, Karen, 2020-11-06
orcidId	0000-0002-0719-5336
publications	[LiteratureReference:9706157] The tyrosine kinase CSK associates with FLT3 and c-Kit receptors and regulates downstream signaling [LiteratureReference:9706120] SOCS proteins in regulation of receptor tyrosine kinase signaling [LiteratureReference:9706052] ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling [LiteratureReference:9706132] Src-Like adaptor protein (SLAP) binds to the receptor tyrosine kinase Flt3 and modulates receptor stability and downstream signaling [LiteratureReference:9706144] Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling [LiteratureReference:9706148] Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal transduction through direct binding to phosphorylated tyrosines 591 and 919 of Flt3 [LiteratureReference:9706098] FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia [LiteratureReference:9697902] The role of SRC family kinases in FLT3 signaling [LiteratureReference:9697909] Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD [LiteratureReference:9697839] FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications [LiteratureReference:9706150] The Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation [LiteratureReference:9605263] FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia [LiteratureReference:9706095] Expression of GADS enhances FLT3-induced mitogenic signaling [LiteratureReference:9706142] Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling [LiteratureReference:9706128] SYK is a critical regulator of FLT3 in acute myeloid leukemia [LiteratureReference:9706062] Adaptor protein Lnk binds to and inhibits normal and leukemic FLT3
schemaClass	Person
surname	Kazi

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