IRS2 is constitutively associated with EPOR and is phosphory...

created [InstanceEdit:9030315] May, Bruce, 2017-11-27
dbId 9030319
displayName IRS2 is constitutively associated with EPOR and is phosphory...
modified [InstanceEdit:9032547] May, Bruce, 2017-12-13
schemaClass Summation
text IRS2 is constitutively associated with EPOR and is phosphorylated on tyrosine residues in response to EPO (Verdier et al. 1997, Bouscary et al. 2003). The phosphorylated IRS2 serves as a docking site for downstream signaling proteins, notably phosphatidylinositol 4,5-bisphosphate 3-kinase (PI3K) (Bouscary et al. 2003).
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