Reactome | The neurotrophic factor BDNF (brain-derived neurotrophic fac...

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created	[InstanceEdit:9024944] Orlic-Milacic, Marija, 2017-10-10
dbId	9024943
displayName	The neurotrophic factor BDNF (brain-derived neurotrophic fac...
literatureReference	[LiteratureReference:9024942] The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor [LiteratureReference:9024955] The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3 [LiteratureReference:9024938] Purification and identification of brain-derived neurotrophic factor from human serum
modified	[InstanceEdit:9025056] Orlic-Milacic, Marija, 2017-10-11
schemaClass	Summation
text	The neurotrophic factor BDNF (brain-derived neurotrophic factor), which functions as a homodimer (Rosenfeld et al. 1995), is a ligand for the neurotrophin receptor tyrosine kinase NTRK2 (TRKB) (Soppet et al. 1991, Klein et al. 1991).

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