Binding of the NOTCH3 coactivator complex to RBPJ response e...
| created | [InstanceEdit:9018554] Orlic-Milacic, Marija, 2017-09-01 |
| dbId | 9018555 |
| displayName | Binding of the NOTCH3 coactivator complex to RBPJ response e... |
| schemaClass | Summation |
| text | Binding of the NOTCH3 coactivator complex to RBPJ response elements in the promoter of the DLGAP5 gene stimulates DLGAP5 transcription. DLGAP5 is involved in G2/M transition and is overexpressed in ovarian cancer cells. NOTCH3 gene is frequently amplified in ovarian cancer (Chen et al. 2012). |
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