Reactome | Signal transducer and activator of transcription 1 alpha/bet...

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created	[InstanceEdit:8987035] Duenas, Corina, 2017-05-05
dbId	8987269
displayName	Signal transducer and activator of transcription 1 alpha/bet...
literatureReference	[LiteratureReference:448739] Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions [LiteratureReference:914210] STATs and gene regulation
modified	[InstanceEdit:9023722] Duenas, Corina, 2017-09-28
schemaClass	Summation
text	Signal transducer and activator of transcription 1 alpha/beta (STAT1) dimer translocates from the cytosol to the nucleus after Interleukin-24 stimulus (IL24) (in BHK cells bearing IL 20RA/IL 20RB) (Parrish Novak et al. 2007). This is a black box event because the mechanism by which this event occurs (diffusion, transport) is unknown (Darnell 1997).

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