Polycistronic transcripts, where a single mRNA can encode se...

created [InstanceEdit:8957402] Jassal, Bijay, 2017-01-25
dbId 8957398
displayName Polycistronic transcripts, where a single mRNA can encode se...
schemaClass Summation
text Polycistronic transcripts, where a single mRNA can encode several different polypeptide chains, are common in prokaryotes. In humans, only 3 bicistronic transcripts have been characterised to date. Human cDNAs encoding both RPP14 of the RNase P complex and mitochondrial 3-hydroxyacyl thioester dehydratase (HTD2) have been isolated. HTD2 functions in the mitochondrial fatty acid synthesis (FAS) pathway, dehydrating (3R)-hydroxyacyl-CoA (3HA-CoA) to trans-2-enoyl-CoA (t2E-CoA) (Autio et al. 2008).
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