Binding of the RUNX1:CBFB or RUNX2:CBFB complex to RUNX resp...

created [InstanceEdit:8938385] Orlic-Milacic, Marija, 2016-09-09
dbId 8938381
displayName Binding of the RUNX1:CBFB or RUNX2:CBFB complex to RUNX resp...
literatureReference
modified [InstanceEdit:9009687] Orlic-Milacic, Marija, 2017-06-22
schemaClass Summation
text Binding of the RUNX1:CBFB or RUNX2:CBFB complex to RUNX response elements in the promoter of the LGALS3 gene stimulates LGLAS3 transcription. The LGALS3 gene encodes Galectin-3, which is highly expressed in pituitary tumors and glioma (Vladimirova et al. 2008, Zhang et al. 2009). Galectin-3 is expressed in myeloid progenitors and its levels increase during the maturation process (Le Marer 2000).
Cite Us!