Binding of the RUNX1:CBFB complex to the promoter of the NFE...

created [InstanceEdit:8938339] Orlic-Milacic, Marija, 2016-09-09
dbId 8938337
displayName Binding of the RUNX1:CBFB complex to the promoter of the NFE...
modified [InstanceEdit:8957311] Orlic-Milacic, Marija, 2017-01-24
schemaClass Summation
text Binding of the RUNX1:CBFB complex to the promoter of the NFE2 gene stimulates NFE2 transcription. The NFE2 gene encodes the Transcription factor NF-E2 45 kDa subunit. The NF-E2 transcription factor regulates erythroid and megakaryocytic maturation and differentiation and is overexpressed in myeloproliferative neoplasms (Wang et al. 2010).
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