Mature single stranded microRNA miR-302b-3p, one of the two ...

created [InstanceEdit:8935882] Orlic-Milacic, Marija, 2016-08-15
dbId 8935881
displayName Mature single stranded microRNA miR-302b-3p, one of the two ...
modified [InstanceEdit:8941592] Orlic-Milacic, Marija, 2016-10-04
schemaClass Summation
text Mature single stranded microRNA miR-302b-3p, one of the two products of miR-302b encoded by the MIR302B gene, binds to the 3'UTR of RUNX1 mRNA, which results in decreased RUNX1 mRNA and protein levels. As it affects RUNX1 mRNA levels, miR-302b is assumed to function as a component of the endonucleolytic RISC, but it is possible that it additionally functions as a component of the nonendonucleolytic RISC. Levels of miR-302b are decreased in epithelial ovarian carcinoma (Ge et al. 2014).
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