Reactome | Bae, SC

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created	[InstanceEdit:8865456] Orlic-Milacic, Marija, 2016-03-22
dbId	8865462
displayName	Bae, SC
firstname	Suk-Chul
initial	SC
publications	[LiteratureReference:9009692] The RUNX family: developmental regulators in cancer [LiteratureReference:8878057] PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis [LiteratureReference:8941878] Pim-1 kinase phosphorylates and stabilizes RUNX3 and alters its subcellular localization [LiteratureReference:8951953] Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation [LiteratureReference:9009301] Prolyl isomerase Pin1-mediated conformational change and subnuclear focal accumulation of Runx2 are crucial for fibroblast growth factor 2 (FGF2)-induced osteoblast differentiation [LiteratureReference:9007714] Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter [LiteratureReference:8952161] The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis [LiteratureReference:8865447] Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons [LiteratureReference:8952372] Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination [LiteratureReference:8937789] Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm [LiteratureReference:8878139] RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD [LiteratureReference:8951941] Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
schemaClass	Person
surname	Bae

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