Reactome | Direct binding of Cbfb to Runx2 was demonstrated using recom...

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created	[InstanceEdit:8865412] Orlic-Milacic, Marija, 2016-03-22
dbId	8865421
displayName	Direct binding of Cbfb to Runx2 was demonstrated using recom...
literatureReference	[LiteratureReference:8865398] Cbfbeta interacts with Runx2 and has a critical role in bone development [LiteratureReference:8865422] Core-binding factor beta interacts with Runx2 and is required for skeletal development
schemaClass	Summation
text	Direct binding of Cbfb to Runx2 was demonstrated using recombinant mouse proteins. The complex of Cbfb and Runx2 plays a critical role in bone development (Kundu et al. 2002, Yoshida et al. 2002).

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