Rab8 is a small GTPase that is specifically involved in the ...

created [InstanceEdit:8854260] Garapati, Phani Vijay, 2016-01-27
dbId 8854248
displayName Rab8 is a small GTPase that is specifically involved in the ...
modified [InstanceEdit:8942936] Garapati, Phani Vijay, 2016-10-21
schemaClass Summation
text Rab8 is a small GTPase that is specifically involved in the regulation of secretory/recycling vesicles, modulation of the actin cytoskeleton, and cell polarity. TBC (Tre2/Bub2/Cdc16) domain family member 17 (TAB1CD17), a member of the Rab GTPase-activating protein, regulates Rab8-mediated endocytic trafficking of transferrin receptor through its interaction with optineurin (OPTN) (Vaibhava et al. 2012).
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