Once recruited to the activated receptor, PI3K phosphorylate...

created [InstanceEdit:8853075] Rothfels, Karen, 2016-01-21
dbId 8853071
displayName Once recruited to the activated receptor, PI3K phosphorylate...
modified [InstanceEdit:9753865] Rothfels, Karen, 2021-09-15
schemaClass Summation
text Once recruited to the activated receptor, PI3K phosphorylates PIP2 to PIP3, leading to activation of AKT signaling. PI3K signaling has been demonstrated downstream of a number of other FGFR mutants (Chen, 2004; Demiroglu, 2001; Guasch, 2001; Byron, 2008; Kunii, 2008; Agazie, 2003; Takeda, 2007; reviewed in Parker et al, 2014; Carter et al, 2015).
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