PTK6 (BRK) phosphorylates tumor suppressor DOK1 on tyrosine ...

created [InstanceEdit:8848786] Orlic-Milacic, Marija, 2015-12-10
dbId 8848787
displayName PTK6 (BRK) phosphorylates tumor suppressor DOK1 on tyrosine ...
modified [InstanceEdit:8849449] Orlic-Milacic, Marija, 2015-12-15
schemaClass Summation
text PTK6 (BRK) phosphorylates tumor suppressor DOK1 on tyrosine residue Y362. PTK6-mediated phosphorylation of DOK1 targets DOK1, through an unknown mechanism, for ubiquitin-dependent proteasome degradation (Miah et al. 2014).
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