Reactome | West, SC

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affiliation	[Affiliation:1243088] Cancer Research UK, London Research Institute
dbId	76734
displayName	West, SC
firstname	Stephen C
initial	SC
modified	[InstanceEdit:8932050] D'Eustachio, Peter, 2016-07-20
publications	[LiteratureReference:216961] Cross-links between Fanconi anaemia and BRCA2 [LiteratureReference:6786163] DNA interstrand crosslink repair and cancer [LiteratureReference:76322] DNA end-joining catalyzed by human cell-free extracts. [LiteratureReference:5686444] Substrate specificity of the MUS81-EME2 structure selective endonuclease [LiteratureReference:83614] Heteroduplex formation by human Rad51 protein: effects of DNA end-structure, hRP-A and hRad52. [LiteratureReference:913303] Synergistic actions of Rad51 and Rad52 in recombination and DNA repair [LiteratureReference:913202] Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1 [LiteratureReference:913262] Distribution of the Rad51 recombinase in human and mouse spermatocytes [LiteratureReference:913216] Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro [LiteratureReference:5686497] Roles of SLX1-SLX4, MUS81-EME1, and GEN1 in avoiding genome instability and mitotic catastrophe [LiteratureReference:5686436] Identification and characterization of the human mus81-eme1 endonuclease [LiteratureReference:913267] Visualization of recombination intermediates produced by RAD52-mediated single-strand annealing [LiteratureReference:83613] Visualisation of human rad52 protein and its complexes with hRad51 and DNA. [LiteratureReference:83611] Precise binding of single-stranded DNA termini by human RAD52 protein. [LiteratureReference:109575] Structure of the single-strand annealing domain of human RAD52 protein. [LiteratureReference:5685830] Role of RAD51C and XRCC3 in genetic recombination and DNA repair [LiteratureReference:5686478] Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells [LiteratureReference:265856] Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2 [LiteratureReference:5677003] DNA-dependent SUMO modification of PARP-1 [LiteratureReference:76312] Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair. [LiteratureReference:5685834] RAD51C is required for Holliday junction processing in mammalian cells [LiteratureReference:83607] Reconstitution of the strand invasion step of double-strand break repair using human Rad51 Rad52 and RPA proteins [LiteratureReference:265918] CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair [LiteratureReference:5685323] The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA [LiteratureReference:83612] The human Rad52 protein exists as a heptameric ring. [LiteratureReference:5686094] Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombination [LiteratureReference:913251] The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51 [LiteratureReference:6785977] Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2 [LiteratureReference:5696661] Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1 [LiteratureReference:914112] RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females [LiteratureReference:5686219] RTEL1 maintains genomic stability by suppressing homologous recombination [LiteratureReference:5686434] Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM
schemaClass	Person
surname	West

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