methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity

accession 0004491
databaseName GO
dbId 70889
definition Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + hydrogencarbonate + NADH + H+. Can also use malonate (3-oxopropanoate) as a substrate. The reaction occurs in two steps with the decarboxylation process preceding CoA-binding. Bicarbonate rather than CO2 is released as a final product.
displayName methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
ecNumber 1.2.1.27
modified [InstanceEdit:9676538] Cook, Justin, 2020-02-17
name methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
referenceDatabase [ReferenceDatabase:1] GO
schemaClass GO_MolecularFunction
url https://www.ebi.ac.uk/QuickGO/term/GO:0004491

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