The human nudix hydrolase peroxisomal NADH pyrophosphatase (...

created [InstanceEdit:6809290] Jassal, Bijay, 2015-11-10
dbId 6809291
displayName The human nudix hydrolase peroxisomal NADH pyrophosphatase (...
modified [InstanceEdit:8940012] Jassal, Bijay, 2016-09-22
schemaClass Summation
text The human nudix hydrolase peroxisomal NADH pyrophosphatase (NUDT12) shows in vitro hydrolase activity towards NAD(P)H, NAD(P)+, ADP-ribose and diadenosine triphosphate. Like other NADH diphosphatases of the Nudix family, NUDT12 has a marked substrate preference for reduced nicotinamide nucleotides. It can hydrolyse NAD(H) to the nicotinamide mononucleotide NMN(H) and may act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism here (Abdelraheim et al. 2003).
Cite Us!