Reactome | A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis

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A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis Show undefined attributes

author	[Person:6786826] Vilardo, E [Person:6786886] Nachbagauer, C [Person:6786870] Buzet, A [Person:6786857] Taschner, A [Person:6785716] Holzmann, J [Person:5696735] Rossmanith, W
created	[InstanceEdit:6786846] May, Bruce, 2015-07-10
dbId	6786889
displayName	A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis
journal	Nucleic Acids Res.
pages	11583-93
pubMedIdentifier	23042678
schemaClass	LiteratureReference
title	A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis
url	http://www.ncbi.nlm.nih.gov/pubmed/23042678
volume	40
year	2012

Referrals

(literatureReference)

[Reaction:R-HSA-6787594] TRMT10C:HSD17B10 (TRMT10C:SDR5C1) methylates adenosine-9 in tRNA yielding 1-methyladenosine-9
[CatalystActivityReference:9643853] tRNA (adenine-N1-)-methyltransferase activity of mtRNase P [mitochondrial matrix] A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis
[Reaction:R-HSA-6787591] TRMT10C:HSD17B10 (TRMT10C:SDR5C1) of mitochondrial RNase P methylates guanosine-9 in tRNA yielding 1-methylguanosine-9
[CatalystActivityReference:9643118] tRNA (guanine-N1-)-methyltransferase activity of mtRNase P [mitochondrial matrix] A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis
[Complex:R-HSA-6808648] TRMT10C:HSD17B10 [mitochondrial matrix]
[Reaction:R-HSA-6786621] TRMT10A methylates guanosine-9 in tRNA
[BlackBoxEvent:R-HSA-6785722] Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript
[BlackBoxEvent:R-HSA-6786854] Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript

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