MEMO1, in complex with phosphorylated ERBB2 heterodimers, as...

created [InstanceEdit:6785650] Orlic-Milacic, Marija, 2015-06-29
dbId 6785649
displayName MEMO1, in complex with phosphorylated ERBB2 heterodimers, as...
modified [InstanceEdit:8854751] Orlic-Milacic, Marija, 2016-01-28
schemaClass Summation
text MEMO1, in complex with phosphorylated ERBB2 heterodimers, associates with the complex of activated RHOA and formin family member DIAPH1. MEMO1 maintains the plasma membrane association of the RHOA:GTP:DIAPH1 complex (Zaoui et al. 2008) and modulates RHOA:GTP:DIAPH1-regulated actin and microtubule dynamics and the consequent cell motility/migration downstream of ERBB2 (Marone et al. 2004, Zaoui et al. 2010).
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