Reactome | Deshaies, RJ

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Deshaies, RJ Show undefined attributes

created	[InstanceEdit:6783349] Jupe, Steve, 2015-06-12
dbId	6783351
displayName	Deshaies, RJ
firstname	Raymond J
initial	RJ
modified	[InstanceEdit:6783353] Jupe, Steve, 2015-06-12
publications	[LiteratureReference:8956000] Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels [LiteratureReference:8955154] Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation [LiteratureReference:8955152] Function and regulation of cullin-RING ubiquitin ligases [LiteratureReference:6783341] JAMM: a metalloprotease-like zinc site in the proteasome and signalosome [LiteratureReference:8953193] Deconjugation of Nedd8 from Cul1 is directly regulated by Skp1-F-box and substrate, and the COP9 signalosome inhibits deneddylated SCF by a noncatalytic mechanism [LiteratureReference:9949893] Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome [LiteratureReference:8956117] NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway [LiteratureReference:9758086] UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover [LiteratureReference:9948454] Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes [LiteratureReference:6783345] Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome [LiteratureReference:6783340] Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1 [LiteratureReference:8953164] Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins [LiteratureReference:9912704] Quantitative measurement of the requirement of diverse protein degradation pathways in MHC class I peptide presentation
schemaClass	Person
surname	Deshaies

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