NCR3 (NKp30) is one of the natural cytotoxicity receptors (N...

created [InstanceEdit:5685483] Garapati, Phani Vijay, 2015-03-27
dbId 5685420
displayName NCR3 (NKp30) is one of the natural cytotoxicity receptors (N...
literatureReference
modified [InstanceEdit:6793282] Garapati, Phani Vijay, 2015-08-31
schemaClass Summation
text NCR3 (NKp30) is one of the natural cytotoxicity receptors (NCRs) expressed mainly on the surface of the natural killer (NK) cells. NKp30 is a major receptor targeting virus-infected cells, malignantly transformed cells, and immature dendritic cells. NCR3 (NKp30) recognizes tumor antigens B7H6, a member of the B7 family (Kaifu et al. 2011, Brandt et al. 2009). B7H6 is not expressed normally, and is found on tumor cells, and sensitizes targets to NCR3-dependent cytotoxicity by NK cells.
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