Reactome | MTMR14 (Jumpy) and MTMR3 are PI3P phosphatases that negative...

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created	[InstanceEdit:5679261] Jupe, Steve, 2015-03-03
dbId	5679226
displayName	MTMR14 (Jumpy) and MTMR3 are PI3P phosphatases that negative...
literatureReference	[LiteratureReference:5679193] Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy [LiteratureReference:5679264] Modulation of local PtdIns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagy [LiteratureReference:5679254] The role of PI3P phosphatases in the regulation of autophagy
modified	[InstanceEdit:5683339] Jupe, Steve, 2015-03-13
schemaClass	Summation
text	MTMR14 (Jumpy) and MTMR3 are PI3P phosphatases that negatively regulate autophagosome formation by dephosphorylating PI3P on phagophores and autophagosomes (Vergne et al. 2009, Taguchi-Atarashi et al. 2010, Vergne & Deretic 2010).

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