As inferred from mouse, RORA binds the promoter of the SREBF...
| created | [InstanceEdit:5663308] May, Bruce, 2015-01-17 |
| dbId | 5663305 |
| displayName | As inferred from mouse, RORA binds the promoter of the SREBF... |
| literatureReference | |
| modified | [InstanceEdit:9936612] May, Bruce, 2025-01-24 |
| schemaClass | Summation |
| text | As inferred from mouse, RORA binds the promoter of the SREBF1 (SREBP1) gene and recruits coactivators to enhance transcription. SREBF1 is a regulator of sterol biosynthesis that interacts with the sterol sensors INSIG1 and INSIG2 in the endoplasmic reticulum membrane (reviewed in Eberle et al. 2004). |
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