Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
Person
>
Entries
Zoncu, R
Show undefined attributes
created
[InstanceEdit:5653922] Jupe, Steve, 2014-12-03
dbId
5653931
displayName
Zoncu, R
firstname
Roberto
initial
R
modified
[InstanceEdit:5653941] Jupe, Steve, 2014-12-03
publications
[LiteratureReference:9646570] mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase
[LiteratureReference:5655429] mTOR: from growth signal integration to cancer, diabetes and ageing
[LiteratureReference:8868547] Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages
[LiteratureReference:8871037] A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism
[LiteratureReference:5653913] Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
[LiteratureReference:5655439] Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1
[LiteratureReference:8871052] A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway
[LiteratureReference:9640261] The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1
[LiteratureReference:9646231] Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex
[LiteratureReference:9646240] A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold
[LiteratureReference:8952709] Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1
schemaClass
Person
surname
Zoncu
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text