Reactome | Zoncu, R

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Zoncu, R Show undefined attributes

created	[InstanceEdit:5653922] Jupe, Steve, 2014-12-03
dbId	5653931
displayName	Zoncu, R
firstname	Roberto
initial	R
modified	[InstanceEdit:5653941] Jupe, Steve, 2014-12-03
publications	[LiteratureReference:9646570] mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase [LiteratureReference:5655429] mTOR: from growth signal integration to cancer, diabetes and ageing [LiteratureReference:8868547] Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages [LiteratureReference:8871037] A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism [LiteratureReference:5653913] Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids [LiteratureReference:5655439] Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1 [LiteratureReference:8871052] A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway [LiteratureReference:9640261] The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1 [LiteratureReference:9646231] Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex [LiteratureReference:9646240] A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold [LiteratureReference:8952709] Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1
schemaClass	Person
surname	Zoncu

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