Reactome | Hannink, M

Schema > Person > Entries

created	[InstanceEdit:5364231] Shamovsky, V, 2014-04-21
dbId	5364216
displayName	Hannink, M
firstname	Mark
initial	M
publications	[LiteratureReference:8932301] Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress [LiteratureReference:9861571] PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria [LiteratureReference:9795444] Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival [LiteratureReference:8932359] Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex [LiteratureReference:9766641] Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway
schemaClass	Person
surname	Hannink

Cite Us!