Reactome | Beachy, PA

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Beachy, PA Show undefined attributes

created	[InstanceEdit:5358009] Rothfels, Karen, 2014-03-27
dbId	5358010
displayName	Beachy, PA
firstname	Philip A
initial	PA
publications	[LiteratureReference:5358251] Tissue repair and stem cell renewal in carcinogenesis [LiteratureReference:5629120] Interactions between Hedgehog proteins and their binding partners come into view [LiteratureReference:5358236] Molecular mechanisms of Sonic hedgehog mutant effects in holoprosencephaly [LiteratureReference:5609753] Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb [LiteratureReference:5610185] Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus [LiteratureReference:5610239] Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells [LiteratureReference:5629141] The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla [LiteratureReference:5362320] Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble form [LiteratureReference:5358209] Autoproteolysis in hedgehog protein biogenesis [LiteratureReference:5628964] Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2 [LiteratureReference:5362304] Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched [LiteratureReference:5358249] The product of hedgehog autoproteolytic cleavage active in local and long-range signalling [LiteratureReference:5358215] Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine [LiteratureReference:5358224] Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain
schemaClass	Person
surname	Beachy

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