Reactome | SETDB1 (ESET, KMT1E) is one of several protein lysine methy...

Schema > Summation > Entries

created	[InstanceEdit:5159248] Jupe, S, 2013-11-22
dbId	5159241
displayName	SETDB1 (ESET, KMT1E) is one of several protein lysine methy...
literatureReference	[LiteratureReference:3301877] Regulation of chromatin structure by site-specific histone H3 methyltransferases [LiteratureReference:3301890] mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression
modified	[InstanceEdit:5159252] Jupe, S, 2013-11-22
schemaClass	Summation
text	SETDB1 (ESET, KMT1E) is one of several protein lysine methyltransferases which selectively methylate lysine-10 of the amino terminus of histone H3 (H3K9) (Rea et al. 2000). It is most effective when complexed with ATF7IP (MCAF, hAM) (Wang et al. 2003).

(summation)

Cite Us!