PIAS2-2 (PIasx-alpha) SUMOylates THRA (isoform alpha-1) with...

created [InstanceEdit:4719399] May, B, 2013-10-19
dbId 4719398
displayName PIAS2-2 (PIasx-alpha) SUMOylates THRA (isoform alpha-1) with...
modified [InstanceEdit:9610530] May, Bruce, 2018-06-10
schemaClass Summation
text PIAS2-2 (PIasx-alpha) SUMOylates THRA (isoform alpha-1) with SUMO3 at lysine-283 and lysine-389 (Liu et al. 2012). (A lysine residue corresponding to lysine-389 does not exist in the alpha-2 isoform of THRA.) SUMOylation by SUMO3 enhances transcription in response to ligand binding.
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