Reactome | Johnston, JA

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created	[InstanceEdit:451894] Jupe, S, 2010-01-14
dbId	451909
displayName	Johnston, JA
initial	JA
publications	[LiteratureReference:539064] Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15 [LiteratureReference:1213519] Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2 [LiteratureReference:451897] Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID [LiteratureReference:1112582] Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways [LiteratureReference:976158] The suppressors of cytokine signalling E3 ligases behave as tumour suppressors [LiteratureReference:453110] Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association [LiteratureReference:877270] Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain [LiteratureReference:1213497] Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID) [LiteratureReference:1112736] The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling
schemaClass	Person
surname	Johnston

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