Reactome | Gherzi, R

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created	[InstanceEdit:449159] May, B, 2009-11-28
dbId	449155
displayName	Gherzi, R
initial	R
publications	[LiteratureReference:450524] A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery [LiteratureReference:449160] AU binding proteins recruit the exosome to degrade ARE-containing mRNAs [LiteratureReference:450416] Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay [LiteratureReference:450413] The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B [LiteratureReference:450498] Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding [LiteratureReference:451193] p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts
schemaClass	Person
surname	Gherzi

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