Reactome | Relaxin receptor 1 (RXFP1 or LGR7) was identified as a recep...

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created	[InstanceEdit:444871] Jupe, S, 2009-10-27
dbId	444860
displayName	Relaxin receptor 1 (RXFP1 or LGR7) was identified as a recep...
literatureReference	[LiteratureReference:444882] H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2 [LiteratureReference:444893] Activation of orphan receptors by the hormone relaxin [LiteratureReference:375241] Relaxin family peptide receptors--former orphans reunite with their parent ligands to activate multiple signalling pathways [LiteratureReference:981471] Membrane receptors: structure and function of the relaxin family peptide receptors
modified	[InstanceEdit:981476] Jupe, S, 2010-10-21
schemaClass	Summation
text	Relaxin receptor 1 (RXFP1 or LGR7) was identified as a receptor for porcine relaxin and subsequently shown to bind human relaxin-2 and relaxin-3.

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