The human gene RhBG encodes a Rhesus blood group family type...

created [InstanceEdit:444414] Jassal, Bijay, 2009-10-23
dbId 444412
displayName The human gene RhBG encodes a Rhesus blood group family type...
modified [InstanceEdit:9954888] Stephan, Ralf, 2025-06-09
schemaClass Summation
text The human gene RhBG encodes a Rhesus blood group family type B glycoprotein which is expressed mainly in the kidney but is also found in the liver (Liu Z et al, 2001). The liver and kidney are important tissues for ammonium metabolism and excretion (Liu Z et al, 2001). RhBG is located on the basolateral membrane of cells in renal collecting ducts (Ludewig U, 2004; Liu Z et al, 2001). Functional studies of human RhBG expressed in Xenopus oocytes indicate it mediates transport of the ammonium analogue methylammonium in an electroneutral manner, consistent with an NH4+/H+ exchange mechanism (Ludewig U, 2004).
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