Reactome | Members of the Vav family are guanine nucleotide exchange fa...

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created	[InstanceEdit:442288] Jupe, S, 2009-09-24
dbId	442275
displayName	Members of the Vav family are guanine nucleotide exchange fa...
literatureReference	[LiteratureReference:389268] Vav-family proteins in T-cell signalling [LiteratureReference:389291] Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product [LiteratureReference:389302] Lck regulates Vav activation of members of the Rho family of GTPases
schemaClass	Summation
text	Members of the Vav family are guanine nucleotide exchange factors (GEFs) for Rho-family GTPases. Vav2 is a GEF for RhoA, RhoB and RhoG, and possibly Rac1 and Cdc42

(summation)

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