The prolactin-releasing peptide receptor (PrRP; GRP10) (Marc...

created [InstanceEdit:388897] Jassal, B, 2008-12-17 14:36:56
dbId 388879
displayName The prolactin-releasing peptide receptor (PrRP; GRP10) (Marc...
literatureReference
modified [InstanceEdit:9024695] Jupe, Steve, 2017-10-06
schemaClass Summation
text The prolactin-releasing peptide receptor (PrRP; GRP10) (Marchese A et al, 1995) is expressed in the pituitary gland (Fujii R et al, 1999) and binds prolactin-releasing peptide (PrRP) (Hinuma S et al, 1998). PrRP is implicated in lactation, regulation of food intake and pain-signal processing. Human PrRP-20 failed to alter basal or forskolin-stimulated levels of intracellular cyclic AMP in HEK293-GPR10 cells, suggesting that GPR10 does not couple via either Gs or Gi (Langmead et al. 2000).
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