GPR31 binds with high affinity the 12-lipoxygenase-derived p...

created [InstanceEdit:3296264] Jupe, S, 2013-04-18
dbId 3296257
displayName GPR31 binds with high affinity the 12-lipoxygenase-derived p...
modified [InstanceEdit:9025131] Jupe, Steve, 2017-10-13
schemaClass Summation
text GPR31 binds with high affinity the 12-lipoxygenase-derived product 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12(S)-HETE). 12-(S)-HETE/GPR31-mediated ERK1/2 activation was inhibited by pertussis toxin, suggesting that the involvement of the G-alpha-i/o heterotrimeric G proteins.
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