Reactome | Nusse, R

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created	[InstanceEdit:3238017] Rothfels, K, 2013-03-27
dbId	3238018
displayName	Nusse, R
firstname	Roel
initial	R
publications	[LiteratureReference:5577026] Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15 [LiteratureReference:208177] The Wnt signaling pathway in development and disease [LiteratureReference:208317] The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling [LiteratureReference:3247732] Wnt proteins [LiteratureReference:517399] Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context [LiteratureReference:208137] Ligand receptor interactions in the Wnt signaling pathway in Drosophila [LiteratureReference:208276] Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless [LiteratureReference:216197] Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein [LiteratureReference:208113] Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex [LiteratureReference:3247729] Lipid-independent secretion of a Drosophila Wnt protein [LiteratureReference:208233] A Drosophila Axin homolog, Daxin, inhibits Wnt signaling [LiteratureReference:5323470] structural Studies of Wnts and identification of an LRP6 binding site [LiteratureReference:3772372] The dishevelled protein is modified by wingless signaling in Drosophila [LiteratureReference:3772328] Casein kinase 2 associates with and phosphorylates dishevelled [LiteratureReference:3238090] Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein [LiteratureReference:5255496] Illegitimate WNT pathway activation by beta-catenin mutation or autocrine stimulation in T-cell malignancies [LiteratureReference:450749] Asymmetric homotypic interactions of the atypical cadherin flamingo mediate intercellular polarity signaling [LiteratureReference:3768849] A new secreted protein that binds to Wnt proteins and inhibits their activities [LiteratureReference:3238087] Wnt proteins are lipid-modified and can act as stem cell growth factors [LiteratureReference:208349] A new member of the frizzled family from Drosophila functions as a Wingless receptor [LiteratureReference:5138423] Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4 [LiteratureReference:3322327] Telomerase modulates Wnt signalling by association with target gene chromatin
schemaClass	Person
surname	Nusse

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