Reactome | Park, M

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Park, M Show undefined attributes

created	[InstanceEdit:3108223] May, B, 2013-02-10
dbId	3108186
displayName	Park, M
firstname	Morag
initial	M
publications	[LiteratureReference:6807007] Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1 [LiteratureReference:8875502] Distinct recruitment of Eps15 via Its coiled-coil domain is required for efficient down-regulation of the met receptor tyrosine kinase [LiteratureReference:3108205] Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin [LiteratureReference:8875559] Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions [LiteratureReference:8875550] Crk synergizes with epidermal growth factor for epithelial invasion and morphogenesis and is required for the met morphogenic program [LiteratureReference:8875664] GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration [LiteratureReference:8874699] A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation [LiteratureReference:5218661] Crk associates with a multimolecular Paxillin/GIT2/beta-PIX complex and promotes Rac-dependent relocalization of Paxillin to focal contacts [LiteratureReference:6807026] Regulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphatase [LiteratureReference:8875182] Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation [LiteratureReference:8876570] DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior
schemaClass	Person
surname	Park

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